• Title/Summary/Keyword: Treatment support

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Current Status of Noninvasive Ventilation Use in Korean Intensive Care Units: A Prospective Multicenter Observational Study

  • Nam, Hyunseung;Cho, Jae Hwa;Choi, Eun Young;Chang, Youjin;Choi, Won-Il;Hwang, Jae Joon;Moon, Jae Young;Lee, Kwangha;Kim, Sei Won;Kang, Hyung Koo;Sim, Yun Su;Park, Tai Sun;Park, Seung Yong;Park, Sunghoon;Korean NIV Study Group
    • Tuberculosis and Respiratory Diseases
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    • v.82 no.3
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    • pp.242-250
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    • 2019
  • Background: Data on noninvasive ventilation (NIV) use in intensive care units (ICUs) are very limited in South Korea. Methods: A prospective observational study was performed in 20 ICUs of university-affiliated hospitals from June 2017 to February 2018. Adult patients (age>18 years) who were admitted to the ICU and received NIV treatment for acute respiratory failure were included. Results: A total of 156 patients treated with NIV were enrolled (mean age, $71.9{\pm}11.6years$). The most common indications for NIV were acute hypercapnic respiratory failure (AHRF, n=89) and post-extubation respiratory failure (n=44). The main device for NIV was an invasive mechanical ventilator with an NIV module (61.5%), and the majority of patients (87.2%) used an oronasal mask. After the exclusion of 32 do-not-resuscitate patients, NIV success rate was 68.5% (85/124); ICU and hospital mortality rates were 8.9% and 15.3%, respectively. However, the success rate was lower in patients with de novo respiratory failure (27.3%) compared to that of patients with AHRF (72.8%) or post-extubation respiratory failure (75.0%). In multivariate analysis, immunocompromised state, de novo respiratory failure, post-NIV (2 hours) respiratory rate, NIV mode (i.e., non-pressure support ventilation mode), and the change of NIV device were significantly associated with a lower success rate of NIV. Conclusion: AHRF and post-extubation respiratory failure were the most common indications for NIV in Korean ICUs. Overall NIV success was achieved in 68.5% of patients, with the lowest rate in patients with de novo respiratory failure.

A study on the factors influence on the family function of persons with mental illness - Comparison of the persons with recent onset and chronic mental illness - (정신질환자 가족기능에 영향을 미치는 요인연구: 발병초기와 만성 정신질환자의 비교)

  • Jo, Eun Jung;Kim, HyunSoo;Kim, Jong Chun
    • Korean Journal of Family Social Work
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    • no.57
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    • pp.99-124
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    • 2017
  • The primary objective of this study is to examine differences between the persons with recent onset and chronic mental illness in their family function; and analyze factors influence on the family function. The independent variables are divided into four sets: socio-economic, clinical, familial, and social characteristics. The subjects of this study are the 628 with mental disorders, and the sample was selected in Pusan and Gyeong-nam area. The findings of this study can be summarized as followed: The family with chronic mental illness showed higher family function in comparison with recent onset. Result of hierarchical multiple regression analysis show that age of onset, difference between ideal and reality in family function variable only influenced family function for the recent onset group, and activities of daily living, difference between ideal and reality in family function, caregiver's health, community support variables influenced family function for the chronic group. The results suggest a need for using different treatment approaches for recent onset versus chronic mentally disabled families. Implications for mental health social work practice for family with disabled are suggested.

Herbal Medicine (Cheonwangbosim-Dan, Tianwangbuxin-Pellet) for Insomnia Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (불면장애에 대한 천왕보심단의 체계적 문헌 고찰 및 메타분석 연구)

  • Sakong, Jong-Won;Kim, Dong-Hee;Ha, Ji-Won;Cho, Yun-Song;Kim, Bo-Kyung
    • Journal of Oriental Neuropsychiatry
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    • v.29 no.4
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    • pp.267-280
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    • 2018
  • Objectives: The objective of this study was to provide clinical evidence to support the use of a herbal medicine (Cheonwangbosim-Dan/Tianwangbuxin-Pellet (TWBXP)) for insomnia. Methods: Randomized controlled trials that verified effects of Herbal Medicine (Cheonwangbosim-Dan, Tianwangbuxin-Pellet) treating primary insomnia were carried out. A literature search of English, Chinese, Korean databases was also performed. The selected literature were assessed by Risk of Bias (RoB). Results: The total number of selected trials was 13 RCTs. Among the 13 RCTs, 10 were meta-analyzed. The Chinese Classification of Mental Disorders-3 (CCMD-3) was frequently used as the diagnostic criteria for interventions during the analysis of the use of herbal medicine (Cheonwangbosim-Dan/Tianwangbuxin-Pellet) for management of primary insomnia. As for outcome measurement, the effective rate was used. From the Meta-analysis of the studies, it was established that the insomnia cure effective rate in the TWBXP group was higher than that in the Western Medicine (WM) group (RR: 1.15, 95% CI: 1.07 to 1.24, p<0.0001, $I^2=33%$). Also, the effective rate in the TWBXP+ACU group was significantly different compared to the WM group (RR: 1.32, 95% CI: 1.13 to 1.54, p=0.0004, $I^2=0%$). The quality of the selected RCTs was low. Conclusions: Herbal medicine (Cheonwangbosim-Dan/Tianwangbuxin-Pellet) is effective for treating primary insomnia. It is worth noting that this studies were of relatively poor quality. The sample sizes were also small. Therefore, further investigations into the diagnosis and treatment of insomnia are warranted.

Systematic Review of Method for Application of Oral Sensorimotor Intervention for Feeding Disorders in Children with Cerebral Palsy (섭식 장애가 있는 뇌성마비 아동에게 적용된 구강감각운동치료방법에 대한 체계적 고찰)

  • Seo, Sang-Min;Min, Kyung-Chul
    • Therapeutic Science for Rehabilitation
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    • v.8 no.3
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    • pp.31-41
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    • 2019
  • Objective: This study was conducted to comprehensively analyze domestic and international literature on the oral sensorimotor intervention approaches and evaluation/non-instrumental assessment methods for children with cerebral palsy with feeding disorders. Methods: One hundred and seventy-six papers published from January 2009 to December 2018 were screened. Forty-seven papers were selected based on the abstract and title, and five papers were selected through a secondary search. Results: The PEDro scale of the selected papers was high with an average of 7 points, and the therapeutic intervention period was found to be between 2 and 6 months, providing therapeutic interventions once to 5 times a week, at least 15 minutes to 1 hour a day. The treatment approach was used with impairment-based intervention and adaptive-based intervention, and the assessment method was divided into clinical evaluation and non-instrumental assessments. Conclusion: Through this systematic review, we found that there are a variety of oral sensorimotor interventions for children with cerebral palsy with feeding disorders. This study provides support for planning oral sensorimotor intervention programs for occupational therapy in clinical practice for children with cerebral palsy.

Effects of Music Therapy Activity on the Stress Change of Alcoholics with Extended Song Sharing (확장된 노래나누기를 중심으로 한 음악치료 활동이 알코올중독자의 스트레스 변화에 미치는 효과)

  • Choi, Kyeong-Yoon;Kim, Sun-Sik
    • Journal of Convergence for Information Technology
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    • v.9 no.9
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    • pp.229-236
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    • 2019
  • This study aims to examine the moderating effect of Extended Song Sharing for helping alcoholics to deal with stress. ESS is structure with non-verbal techniques approaches traditional Song Sharing technique. For this study, 64 alcoholics hospitalized were experimental (n=33) and control groups (n=31). The group was asked to participate in 12 ESS programs twice a week, every 45 minutes for six weeks. During this period, all those who belonged to the experimental and control groups were required to continue to participate in treatment programs prescribed by hospitals. Result: ESS interventional effects on subjects were evaluated using a stress response scale. As a result of the experiment, the WCC score of the experimental group increased 7.3% (p=0.000) but there was almost no change in the control group (1.5% increase, p=0.019). Effects of WCC types were higher in the experimental group, followed by 13.67% (p=0.006) in coping with wishful thinking, 9.66% (p=0.000) in the pursuit of social support, 6.35% (p=0.000) in dealing with problems, and 4% (p=0.000) in coping with emotions. ESS activities have been confirmed to improve the way alcoholics cope with stress.

Taxonomic studies of the tribe Potentilleae (Rosaceae) in Korea (한국산 양지꽃족(장미과)의 분류학적 연구)

  • HEO, Kyeong-In;LEE, Sangryong;KIM, Yongsung;PARK, Jongsun;LEE, Sangtae
    • Korean Journal of Plant Taxonomy
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    • v.49 no.1
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    • pp.28-69
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    • 2019
  • We conducted taxonomical investigations based on morphological characteristics, fruit morphology, and literature research on the tribe Potentilleae (Rosaceae) in Korea covering seven genera and 24 species. The style position on the ovary and the shape of style were useful characteristics for the classification of subtribal and generic levels in the tribe Potentilleae. The subtribe Fragariinae is characterized by subbasal or lateral style on the ovary and anthers with one theca. The subtribe Potentillinae has a subterminal style on the ovary, except for Argentina, which presents a subterminal and lateral style and anthers with two thecae. These results support the recent taxonomic recognition that i) the tribe Potentilleae consists of two subtribes, and ii) genera such as Dasiphora, Comarum, and Sibbaldianthe sometimes included in Potentilla s.l. are treated as independent genus. In the subtribe Potentillinae, Argentina, which has been treated as Potentilla, is supported as a distinct genus according to the characteristics of the subterminal and lateral style position and the ventral stipular auricles. In Fragaria, F. nipponica subsp. chejuensis, which has generally small leaves and a limited distribution only on Hallasan Mt., is supported by treatment as an endemic species. Duchesnea chrysantha is distinguished from D. indica by the characteristics of light green or yellowish green leaves, thin and somewhat membranous leaflets, and broad ovate or obovate leaflets. Each complex of P. dickinsii and P. chinensis remains unresolved with regard to controversy over the taxonomic circumscription due to their external morphological variations. Additional taxonomical research and molecular population studies are required for a more in-depth understanding of the tribe Potentilleae in Korea.

Technology Convergence & Trend Analysis of Biohealth Industry in 5 Countries : Using patent co-classification analysis and text mining (5개국 바이오헬스 산업의 기술융합과 트렌드 분석 : 특허 동시분류분석과 텍스트마이닝을 활용하여)

  • Park, Soo-Hyun;Yun, Young-Mi;Kim, Ho-Yong;Kim, Jae-Soo
    • Journal of the Korea Convergence Society
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    • v.12 no.4
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    • pp.9-21
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    • 2021
  • The study aims to identify convergence and trends in technology-based patent data for the biohealth sector in IP5 countries (KR, EP, JP, US, CN) and present the direction of development in that industry. We used patent co-classification analysis-based network analysis and TF-IDF-based text mining as the principal methodology to understand the current state of technology convergence. As a result, the technology convergence cluster in the biohealth industry was derived in three forms: (A) Medical device for treatment, (B) Medical data processing, and (C) Medical device for biometrics. Besides, as a result of trend analysis based on technology convergence results, it is analyzed that Korea is likely to dominate the market with patents with high commercial value in the future as it is derived as a market leader in (B) medical data processing. In particular, the field is expected to require technology convergence activation policies and R&D support strategies for the technology as the possibility of medical data utilization by domestic bio-health companies expands, along with the policy conversion of the "Data 3 Act" passed by the National Assembly in January 2019.

Restoration of patient accelerating anterior teeth wear by loss of posterior support: Case report (구치부 지지 소실에 의한 전치부 마모 가속화 환자의 수복: 증례보고)

  • Choi, Hyejin;Lee, Jaehoon
    • The Journal of Korean Academy of Prosthodontics
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    • v.57 no.4
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    • pp.382-388
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    • 2019
  • Increased anterior teeth mastication following posterior teeth loss leads to greater anterior occlusal force. It may cause greater attrition of anterior teeth, traumatic force occlusion (TFO), also often followed by antagonist extrusion and occlusal disharmony. This clinical report describes the treatment for a 67-year-old female patient diagnosed with loss of both maxillary and left mandibular posterior teeth, severe attrition of maxillary and mandibular anterior teeth and extrusion of multiple teeth. A diagnostic cast was mounted on articular in centric relation (CR) position to evaluate vertical dimension (VD) and interspace. To provide adequate space for the prosthetic reconstructions, VD was increased by 3 mm on the anterior pin. And then diagnostic wax-up was completed upon that VD. Wax-up was converted to provisional restorations and verified in the patient's mouth and the final restorations were delivered. Clinical follow up examination held 3 months after temporary restoration owing to changes in vertical dimension revealed proper function in mastication without evidence of temporo-mandibular joint (TMJ) disorders. This clinical report presents successfully restoring severe attrition case with increasing vertical dimension resulting in satisfaction in esthetics and function.

Induction of systemic resistance against Phytophthora blight by Enterobacter asburiae ObRS-5 with enhancing defense-related genes expression (역병에 대한 Enterobacter asburiae ObRS-5 처리의 유도저항성 발현)

  • Kim, Dayeon;Jeon, Yong Hee;Ahn, Jea-Hyung;Ahn, Si Hyeon;Yoon, Young Gun;Park, In Cheol;Park, Jin Woo
    • Korean Journal of Environmental Biology
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    • v.38 no.4
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    • pp.724-732
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    • 2020
  • Phytophthora capsici is the organism that causes Phytophthora blight which infects red pepper plants prolifically, ultimately leading to crop loss. A previous study revealed that Enterobacter asburiae ObRS-5 suppresses Phytophthora blight in both red pepper and Ligularia fischeri plants. In order to determine whether the induced systemic resistance (ISR) was triggered by pre-infection with the ObRS-5 strain, we conducted quantitative PCR using primers for PR1, PR4, and PR10, which correlate with systemic resistance in red-pepper plants. In our results, red pepper plants treated with the ObRS-5 strain demonstrated increased expression of all three systemic resistance genes when compared to controls in the glasshouse seedling assay. In addition, treatment of red peppers with the ObRS-5 strain led to reduced Phytophthora blight symptoms caused by P. capsici, whereas all control seedlings were severely affected. Perhaps most importantly, E. asburiae ObRS-5 was shown to induce the ISR response in red peppers without inhibiting growth. These results support that the defense mechanisms are triggered by ObRS-5 strain prior to infection by P. capsici and ObRS-5 strain-mediated ISR action are linked events for protection to Phytophthora blight.

Efficacy of glycine powder air-polishing in supportive periodontal therapy: a systematic review and meta-analysis

  • Zhu, Mengyuan;Zhao, Meilin;Hu, Bo;Wang, Yunji;Li, Yao;Song, Jinlin
    • Journal of Periodontal and Implant Science
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    • v.51 no.3
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    • pp.147-162
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    • 2021
  • Purpose: This systematic review and meta-analysis was conducted to assess the effects of glycine powder air-polishing (GPAP) in patients during supportive periodontal therapy (SPT) compared to hand instrumentation and ultrasonic scaling. Methods: The authors searched for randomized clinical trials in 8 electronic databases for relevant studies through November 15, 2019. The eligibility criteria were as follows: population, patients with chronic periodontitis undergoing SPT; intervention and comparison, patients treated by GPAP with a standard/nozzle type jet or mechanical instrumentation; and outcomes, bleeding on probing (BOP), patient discomfort/pain (assessed by a visual analogue scale [VAS]), probing depth (PD), gingival recession (Rec), plaque index (PI), clinical attachment level (CAL), gingival epithelium score, and subgingival bacteria count. After extracting the data and assessing the risk of bias, the authors performed the meta-analysis. Results: In total, 17 studies were included in this study. The difference of means for BOP in patients who received GPAP was lower (difference of means: -8.02%; 95% confidence interval [CI], -12.10% to -3.95%; P<0.00001; I2=10%) than that in patients treated with hand instrumentation. The results of patient discomfort/pain measured by a VAS (difference of means: -1.48, 95% CI, -1.90 to -1.06; P<0.001; I2=83%) indicated that treatment with GPAP might be less painful than ultrasonic scaling. The results of PD, Rec, PI, and CAL showed that GPAP had no advantage over hand instrumentation or ultrasonic scaling. Conclusions: The findings of this study suggest that GPAP may alleviate gingival inflammation more effectively and be less painful than traditional methods, which makes it a promising alternative for dental clinical use. With regards to PD, Rec, PI, and CAL, there was insufficient evidence to support a difference among GPAP, hand instrumentation, and ultrasonic scaling. Higher-quality studies are still needed to assess the effects of GPAP.