• Title/Summary/Keyword: Treatment failures

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Analysis of Treatment Failures in Early Uterine Cervical Cancer (조기 자궁경부 악성종양의 치료실패에 대한 분석)

  • Kim Joo-Young;Lee Kyu-Chan;Choi Hyung-Sun
    • Radiation Oncology Journal
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    • v.9 no.2
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    • pp.285-291
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    • 1991
  • One hundred and twenty six patients with early uterine cervical cancer who had been treated at Departmen of Radiation Oncology of Korea University Hospital from Jan.1981 to Dec.1988 were analysed retrospectively by the treatment result and pattern of of failures. All patients had stage Ia to IIa disease and were grouped whether they had combination of operation and postop irradiation or radiation therapy alone. 1) Sixty six patients belonged to the combination treatment group and 60 patients to the radiation alone group. 2) Combination group consisted of $18.1\%$(12/66) stage Ia, $71.2\%$(47/66) stage Ib and $10.6\%$ (7/66) stage IIa patients. There were no stage Ia, 18.8$\%$(l1/60) stage Ib and 81.6$\%$(49/60) stage IIa patients for RT alone gronp. 3) There were total 23$\%$(29/126) treatment failures,13 patients in combination group and 16 patients in RT alone group. In 66 patients of combination group, they were found to have 5 locoregional failures, 7 distant failures and 1 at both sites. In 60 patients of RT alone group, 9 locoreginal failure and 7 distant failures occured. Eighty six percent (25/29) of total failures appeared within 18 month after completion of treatment. About 60$\%$ of the patients with regional recurrences which were located at pelvic side wall or pelvic lymph nodes paesented their recurrent disease after 1 year of completion of treatment, whereas same percent of distant failures appeared within 6 month. 5) In RT alone group, the first sites of distant failure were mostly para-aortic lymph node and/or left supraclavicular lymph node (71.4$\%$,5/7). In combination group, various sites such as inguinal lymph node, mediastinal lymph node, liver, lung and bone appeared first or at the same time with para-aortic and supraclavicular lymph node metastasis. 6) Logistic regression analysis was done for multivariate analysis of the factors contributing to locoregional and distant failures. In combination group, adequacy of the resection margin and the presence of positive pelvic node were found to be the most significant factors (p=0.0423 & 0.0060 respectively). In RT alone group, less than complete regression of the tumor at the end of treatment was the only significant contributing factor for the treatment failures (p=0.0013) with good liklihood ratio.

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Studies on Diagnosis and Treatment of Major Reproductive Failures in Dairy Cows (젖소 번식장애 주요 유형별 치료방법에 관한 연구)

  • 조성우;김용준;이해이;김용수
    • Korean Journal of Animal Reproduction
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    • v.25 no.3
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    • pp.207-217
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    • 2001
  • Diagnosis and treatment of major reproductive failures were carried out for 836 dairy cows of 12 farms in Kimje area from May 1999 to May 2000. Reproductive failures were classified into four categories: uterine diseases, ovarian diseases, combination of uterine and ovarian diseases, and anestrus with corpus luteum (CL), based on the diagnosis by both rectal palpation and ultrasonography (SA 600, Medison, 5.OMHz transducer). 1. Of 102 cows examined, 15 cows were diagnosed as pregnant. Cows with real reproductive failures were therefore 87 cows and the rate of reproductive failures far all the cows of 12 farms was 10.4% (87/836). 2. Of 57 cows with reproductive failures, the cows with uterine diseases were 33 heads (37.9%), with ovarian diseases: 30 heads (34.5%), with combination form: 16 heads (18.4%), and with anestrus with CL: 8 heads (9.2%). 3. Of 87 cows with reproductive failures, 7 cows were slaughtered and 80 cows were treated by hormone or douche. The cows expressed estrus were 74 cows (92.5%, 74/80 heads) and 56 cows were pregnant (70.0%, 56/80 heads) following treatment. 4. The reproductive failures tended to be increased as the period proceeded from 30 days (2.3%, 2/87 heads) to over 120 days (56.3%, 49/87 heads) after parturition. 5. Associated other diseases to reproductive failures were foot diseases(5 cows), joint diseases (5 heads), urovagina (6 heads), and rectovaginal fistula (2 cows) and the rate of occurrence of associated diseases was 20.7% (18/87 heads). 6. No reproductive record was used in 7 farms of 12 farms and 5 farms had no play ground or not used for the cows. These results indicated that diagnosis fur reproductive failures by rectal palpation along with ultrasonography was more accurate than the conventional rectal palpation and brought better result of treatment for major types of reproductive failures. It was also indicated that non-uses of reproductive record and play ground were also important factors in occurrence of reproductive failures.

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Statistical analysis of failures of a medical linear accelerator over ten years (선형가속기의 10년간 관리 자료를 바탕으로 한 통계분석)

  • Ju, Sang-Gyu;Huh, Seung-Jae;Han, Young-Yih;Seo, Jeong-Min;Kim, Won-Kyou;Kim, Tae-Jong;Park, Young-Hwan
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2004.11a
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    • pp.158-161
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    • 2004
  • In order for better management of a medical linear accelerator, the records of the operational failures of Varian CL2100C over ten years were analyzed. The failures were classified according to the involved functional subunits and each class was rated into three levels depending on operational conditions. The relationship between the failure rate and working ratio was investigated. Among the recorded failures ( total 587 failures), the most frequent failure, which was 20% of the total. was observed in the parts related to the collimation system including monitor chamber. Regrading to the operational conditions, the 2nd level of failures, that temporally interrupted treatments, was the most frequent. The 3rd level of failures, that interrupted treatment for more than several hours, was mostly caused by the accelerating subunit. The average life-time of a Klystron and Thyratron became shorter as the working ratio increased, which was 42 and 83% of the expected values, respectively. Recording equipment problems and failures in detail over a long period of time can provide a good knowledge of equipment function as well as the capability to forecast future failure. More rigorous equipment maintenance is required for old medical linear accelerator to avoid the serious failure in advance, and improve the patient treatment quality.

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Effect on the Stabilizing Heat Treatment to Weld Joint for the USC Coal Boiler Tubes(SA213 TP347H) (초초임계 석탄발전 보일러 튜브(SA213 TP347H) 용접부 안정화 열처리 효과)

  • Ahn, Jong-Seok;Park, Jin-Keun;Lee, Gil-Jae;Yoon, Jae-Yeon
    • Journal of Welding and Joining
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    • v.33 no.4
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    • pp.30-36
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    • 2015
  • Austenite stainless steel(SA213-TP347H) has widely been used for the superheater & reheater tube in USC(ultra-supercritica) coal boiler because of its high creep rupture strength and anti-oxidation. But recently, the short-term failures have happened frequently in heat affected zone for only 4,000~15,000hours of service. Many investigations have been conducted to understand the failure mechanism. The root cause of failure was comfirmed to "strain induce participation hardening crack" or "reheat cracking". This mechanism often occurred due to weld residual stress and precipitation of the Cr, Nb carbides in the stabilized stainless steel such as TP347H. This paper presents an analysis of failure tube and effect of the sample tubes that conducting stabilizing heat treatment in site after 11,380hours & 16,961hours of service. Visual inspection was performed. In addition, microscopic characteristics was identified by O.M, SEM, and hardness test was carried out to find out the heat treatment effects. Failures seem to happen because of being not conducted stabilizing heat treatment in site. And another cause is inadequate weld parameter such as pass, ampere, voltage, inter-pass temperature. Thus, this paper has the purpose to describe that how to prevent similar failures in those weld-joints.

Development of a Computer Code for Common Cause Failure Analysis (공통원인 고장분석을 위한 전산 코드 개발)

  • Park, Byung-Hyun;Cho, Nam-Zin
    • Nuclear Engineering and Technology
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    • v.24 no.1
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    • pp.14-29
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    • 1992
  • COMCAF, a computer code for the common-cause failure analysis, is developed to treat the common-cause failures in nuclear power plants. In the treatment of common-cause failures, the minimal cut sets of the system are obtained first without changing the fault-tree structure. The occurrence probabilities of the minimal cut sets are then calculated accounting for the common-cause failures among components in the same minimal cut set or in different minimal cut sets. The basic parameter model is used to model the common-cause failures between similar or identical components. For dissimilar components, the assumption of symmetry used in the basic parameter model is applied to the basic events affecting two or more components. The top event probability is evaluated using the inclusion-exclusion method. In addition to the common-cause failures of components in the same minimal cut sets, failures of components in the different minimal cut sets are also easily accounted for by this method. This study applied this common-cause failure analysis to the PWR auxiliary feedwater system. The results in the top event probability for the system are compared with those of no common-cause failures.

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Microsurfacing Successes and Failures (마이크로서페이싱의 성공과 실패 사례)

  • Kim, Hyun Hwan;Benjamin, Broughton;Lee, Moon Sup;Lee, Soon Jae
    • International Journal of Highway Engineering
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    • v.17 no.2
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    • pp.71-78
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    • 2015
  • PURPOSES: This study set out to investigate the current state of microsurfacing in Texas and compared the results with the current state of the practice nationwide. METHODS: For this study, case studies were extracted from the existing literature and compared with the data obtained both from site visits by the research team and data obtained from a survey by Texas Department of Transportation (TxDOT) personnel. The successes and failures of microsurfacing are detailed and explanations of different issues are outlined. Forensic studies from Texas are included in the descriptions of those microsurfacings that failed when configured as part of the cape seals. RESULTS : Microsurfacing has been shown to be an effective pavement preservation technique when applied to an appropriate road, at an appropriate timing, and as a remedy for certain issues. The failures experienced in Texas can mostly be attributed to cape seals and an inability to recognize structurally faulty pavement. CONCLUSIONS : When applied to an appropriate road, at an appropriate timing, and as a remedy for certain issues, microsurfacing has been shown to perform well in numerous case studies. The majority of microsurfacing failures are the result of poor project selection, usually involving the treatment being applied to structurally unsound pavement.

Dental implant failures and complications - Retrospective study (치과 임플란트 실패와 합병증의 후향적 연구)

  • Park, Ju-Hee;Jo, Chan Woo;Woo, Jae-Man;Kahm, Se Hoon
    • The Journal of the Korean dental association
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    • v.57 no.7
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    • pp.372-378
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    • 2019
  • The dental implants in modern dentistry brought out a new era in everyday dental practice. Increasing of dental implants usage, various failures and complications has occurred. Failures and complications of dental implant treatments that can happen in implant surgery, in mechanical or prosthetic problem and in biological aspect. The aim of this study was to assess implant failures for 6 years as well as find out how to overcome implant failure. In Jeju National University hospital, 26 dental implants in 17 patients were removed by implant failure through 2013.1.1.-2018.12.31. Each implant failure case was analyzed in report form with various informations about failure retrospectively. The present study showed 26 failed dental implants of 17 patients were removed. 13 implants(50%) of 8 patients(47.06%) were failed before functional loading and 13 implants(50%) of 9 patients(52.94%) were failed after functional loading. 11 implants(42.31%) of 7 patients(41.18%) with medical disease were extracted. 6 implants(23.08%) of 5 patients(29.41%) with additive bone graft were failed. We discuss with 26 failed dental implants of 17 patients about their causes, solutions and prevention retrospectively for 6 past years. Precise diagnosis and treatment planning are needed. Medically compromised patients and patients with implants and additive bone grafts should be cautiously treated with high failing possibilities.

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Spontaneous Lead Breakage in Implanted Spinal Cord Stimulation Systems

  • Kim, Tae-Hun;Lee, Pyung-Bok;Son, Hye-Min;Choi, Jong-Bum;Moon, Jee-Youn
    • The Korean Journal of Pain
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    • v.23 no.1
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    • pp.78-81
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    • 2010
  • Spinal cord stimulation (SCS) has become an established clinical option for treatment of refractory chronic pain. Current hardware and implantation techniques for SCS are already highly developed and continuously improving; however, equipment failures over the course of long-term treatment are still encountered in a relatively high proportion of the cases treated with it. Percutaneous SCS leads seem to be particularly prone to dislocation and insulation failures. We describe our experience of lead breakage in the inserted spinal cord stimulator to a complex regional pain syndrome patient who obtained satisfactory pain relief after the revision of SCS.