• 신재생에너지
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• 제20권2호
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• pp.35-43
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• 2024

A pump turbine is a technically matured option for energy production and storage systems. At the off-design operating range, the pump turbine succumbed to flow instabilities, which correlated with the pump turbine geometry. A low specific speed pump turbine was designed and modified according to the impeller blade angle. Reynolds-Average Navier-Stokes is carried out with a shear stress transport turbulence model to evaluate the detailed flow characteristics in the pump turbine. The impeller blade inlet angle (𝛽₁) and outlet angle (𝛽₂) are used to evaluate hydraulic loss in the pump turbine. When 𝛽₁ changed from low to high value, the maximum efficiency is increased by 4.75% in turbine mode. The S-Curve inclination is reduced by 8% and 42% for changes in 𝛽₁ and 𝛽₂ from low to high values, respectively. At α = 21°, the shock loss coefficient (𝜁_s) is reduced by 16% and 19% with increases of 𝛽₁ and 𝛽₂ from low to high values, respectively. When 𝛽₁ and 𝛽₂ values increased from low to high, the impeller friction coefficient (𝜁_f) increased and decreased by 20% and 8%, respectively. Hence, the high 𝛽₂ effectively reduced the loss coefficient and S-Curve inclination.

• 한국ITS학회 논문지
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• 제13권1호
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• pp.1-14
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• 2014

국가정책 및 사회적 여건의 변화에 따라 도시부의 교통혼잡 완화를 위한 물리적 도로 확대가 한계에 다다른 지금 혼잡 완화를 위해서는 기존 도로의 효율성을 재고하는 방안이 간구되어야한다. 또한 지능형교통체계(ITS)는 과거 루프 및 영상검지기 등을 통한 도로기반 지점검지 중심의 교통정보 수집체계에서 도로, 자동차 및 보행자간의 다양한 수집 체계를 통한 실시간 구간검지 체계 중심의 차세대 지능형교통체계(C-ITS :Co-operative ITS)로 빠르게 진화하고 있으나 현재 교차로의 운영 및 제어를 위한 교통정보의 수집방법은 지점검지체계에 국한되어 있는 실정이다. 따라서 본 연구는 현재 Hi-pass에 적용된 DSRC기술을 통해 수집이 가능한 구간정보를 이용하여 접근로의 대기행렬 길이를 산정하고 이를 활용하는 독립교차로의 실시간 신호제어모형의 개발 및 평가를 목적으로 하였다. 대기행렬길이 추정을 위해 구간검지기를 통해 수집된 개별차량의 통행시간을 이용하여 시공도 상에 4개의 좌표값을 추정하였으며 한 주기동안 추정된 좌표값들을 통해 대기행렬이 생성되는 충격파의 속도 및 대기행렬길이를 추정하였다. 실시간 신호제어를 위해 각 방향별 추정된 대기행렬길이를 통해 전체 교차로의 대기행렬길이의 합이 최소가 되는 신호시간을 산정하였으며 API 기능을 제공하는 미시적 시뮬레이션 프로그램인 VISSIM을 활용하여 총 3개의 시나리오를 평가하여 알고리즘에 의해 교차로의 대기행렬 길이의 합이 최소가 되는 신호시간의 산정이 가능함을 확인하였다.

• 한국ITS학회 논문지
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• 제15권3호
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• pp.45-51
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• 2016

기존 실시간 신호제어시스템은 과포화 상황, 지점검지 및 매설식 검지체계의 문제점이 제기됨에 따라 ITS의 활성화와 검지체계의 발전 등으로 진보된 차세대 신호제어시스템의 개발이 요구되고 있다. 본 논문은 차세대 신호제어시스템을 위해 신호제어 기초 변수를 기존 통과교통량이 아닌 교차로 대기행렬을 활용할 수 있도록 대기행렬길이의 산출을 목적으로 하였다. 기존 시스템의 한계로 나타난 과포화 상황에 중점을 두어 범위를 설정하였다. 실시간으로 수집되는 개별차량 위치정보를 좌표로 변환하여 최소제곱법을 이용한 회귀모형에 적용하여 추출한 직선식을 충격파 모형에 적용하였다. 산출된 대기길이와 링크길이의 비교를 통해 대기길이가 링크를 초과하는 경우 상류부 대기차량이 하류부 교차로에 영향을 미친다고 판단하여 하류부 교차로 대기행렬까지 대기길이로 포함하였다. 추출된 대기행렬길이의 신뢰성을 판단하고자 링크 통행시간과의 상관분석을 실시한 결과 두 링크 모두 0.9이상의 수치를 나타내며 높은 상관관계를 보이는 것으로 판단되었다. 본 연구는 실시간으로 수집되는 데이터를 이용하여 대기행렬길이를 산출할 수 있다는 점과 이를 이용하여 신호제어시스템의 개선에 기여할 수 있다는데 의의가 있다.

• Korean Journal of Acupuncture
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• 제29권2호
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• pp.260-270
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• 2012

Objectives : Hippocampus, a region of temporal lobe, plays an important role in the pathogenic mechanisms of brain diseases such as Alzheimer's disease, depression and temporal lobe epilepsy. This research is designed to investigate hippocampal changes after acupuncture stimulation at Shinmun(HT7) using 2-dimensional gel electrophoresis(2-DE). Methods : On postnatal-day 15, rat pups were randomly devided into Normal(NOR) or HT7 group. All of Pups kept with their mothers for 7 days, but pups in HT7 group received acupuncture stimulation at HT7 daily. On postnatal-day 21, hippocampus of each rat pup was dissceted 30 minutes after last acupuncture stimulation and the protein expressions were investigated using 2-DE. Results : After acupuncture stimulation at HT7, expression of 20 proteins were significantly increased. Succinate semialdehyde dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase-like, transketolase, aconitate hydratase and phosphoglucomutase-1 were related to glucose methabolism. Eukaryotic initiation factor(eIF) 4A-II, eIF 4A-III, mitochondrial Tu translation elongation factor and chain A of crystal structure of the 70-Kda heat shock cognate protein involve in the protein synthesis in ribosome. Tubulin ${\beta}$-4 chain, tubulin T ${\beta}$-15 and tubulin ${\alpha}$-1B chain comprise cytoskeleton. Glutathione S-transferase(GST) ${\omega}$-1, GST P and GST Yb-3 can reduce oxidative stress. ${\beta}$-soluble N-ethylmaleimide-sensitive fusion protein attachment protein is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus, glycerol-3-phosphate dehydrogenase plays a major role in lipid biosynthesis, creatine kinase U-type catalyses the conversion of creatine and consumes adenosine triphosphate to create phosphocreatine and adenosine diphosphate. Platelet-activating factor acetylhydrolase IB subunit alpha and voltage depedent anion-selective channel protein 2 were also increased. Conclusions : The results suggest that acupuncture stimulation at HT7 may enhance glucose and lipid metabolism, protein synthesis, cytoskeletal substance and anti-oxidative stress in hippocampus.

• Journal of Trauma and Injury
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• 제25권3호
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• pp.79-86
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• 2012

Purpose: The most common cuase of transfusion for trauma victims in an emergency department is hypovolemic shock due to injury. After an injury to an internal organ of the chest or the abdomen, transfusion is needed to supply blood products and to compensate tissue oxygen transport and bleeding. From the 1990's, there have been some reports that transfusion is one of the major factors causing multiple-organ failure. Thus, as much as possible, tranfusion has been minimized in the clinical setting. This study aims to analyze the prognostic factors for mortality among trauma victims transfused with blood products in an emergency department. Methods: We conducted this study for the year of 2010 retrospectively. The study group included adult trauma victims tranfused with blood products in our ED. The exclusion criteria were discharge against medical advice, and missing follow-up due to transfer to another facility. During the study period, 34 adult trauma victims were enrolled. We compared the clinical variables between survivors and non-survivors. Results: the mean age of the 34 victims was 58.06 years, and males account for 58.5% of the study group. The most-frequently used form transportation was ambulance(119, 55.9%), and the most common injury mechanism was mobile vehicle accidents(67.6%). The mean revised trauma score (RTS) was 5.9, and the mean injury severity score (ISS) was 47.76. The mortality rate in the ED was 58.5%, Comparison of survivors with non-survivors showed statistical differences in injury mechanism, initial SBP, DBP, RTS, ISS, and some laboratory data such as AST, ALT, pH, PO2, HCO3, glucose (p<0.05). Regression analyses showed that mortality among adult trauma victims transfused in the ED correlated with RTS. Conclusion: When an adult trauma victim is transported to the ED and needs a tranfusion, the emergency physician carefully assess the victim by using physiologic data.

• 자원ㆍ환경경제연구
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• 제23권4호
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• pp.689-718
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• 2014

본 연구는 홍수피해가 관련 산업부문의 자본을 감소시킬 경우 국가경제에 미치는 파급효과를 완전예측형 동태CGE모형을 이용하여 2010년을 기준연도로 분석하였다. 여러 홍수피해 항목들 중에서 통계자료가 확보될 수 있는 농경지, 선박, 공공시설의 물적 피해 항목에 분석을 한정하였다. 홍수피해의 시나리오는 1991년~2010년 기간 홍수피해를 2010년 기준으로 불 변화하여 항목별 홍수피해의 평균과 최대로 각각 채택하였다. 분석 결과, 산업별 생산의 경우에는 자본스톡이 직접적으로 감소하는 수산업+운송업의 생산 감소율이 가장 크고 다음으로 농임 업의 생산감소율이 큰 것으로 나타났다. GDP는 충격 기준연도에 벤치마크 해 대비로는 0.001%~0.057% 그리고 초기 자본감소 대비로는 약 11% 감소하는 것으로 분석되었다. 동태적으로는 GDP는 말기로 가정된 2030년까지 서서히 감소하는 것으로 분석되어서 홍수피해가 자본을 감소시킬 경우 국가경제에 미치는 영향력은 오래 지속되는 것으로 나타났다.

• 한국초지조사료학회지
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• 제36권3호
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• pp.237-242
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• 2016

Copper (Cu) is a necessary microelement for plants. However, high concentrations of Cu are toxic to plants that change the regulation of several stress-induced proteins. In this study, an annealing control primer (ACP) based approach was used to identify differentially expressed Cu-induced genes in alfalfa leaves. Two-week-old alfalfa plants (Medicago sativa L.) were exposed to Cu for 6 h. Total RNAs were isolated from treated and control leaves followed by ACP-based PCR technique. Using GeneFishing ACPs, we obtained several genes those expression levels were induced by Cu. Finally, we identified several genes including UDP-glucuronic acid decarboxylase, transmembrane protein, small heat shock protein, C-type cytochrome biogenesis protein, mitochondrial 2-oxoglutarate, and trans-2,3-enoyl-CoA reductase in alfalfa leaves. These identified genes have putative functions in cellular processes such as cell wall structural rearrangements, transduction, stress tolerance, heme transport, carbon and nitrogen assimilation, and lipid biosynthesis. Response of Cu-induced genes and their identification in alfalfa would be useful for molecular breeding to improve alfalfa with tolerance to heavy metals.

• Journal of Microbiology and Biotechnology
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• 제17권6호
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• pp.934-944
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• 2007

Paenibacillus polymyxa E681 is known to be able to suppress plant diseases by producing antimicrobial compounds and to promote plant growth by producing phytohormones, and secreting diverse degrading enzymes. In spite of these capabilities, little is known regarding the flow of information from the bacterial strain to the barley roots. In an attempt to determine the flow of information from the bacterial strain to barley roots, the strain was grown in the presence and absence of barley, and two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and MALDI-TOF mass spectrometry were used. 2D-PAGE detected approximately 1,000 spots in the cell and 1,100 spots in the supernatant at a pH 4-10 gradient. Interestingly, about 80 spots from each sample showed quantitative variations. Fifty-three spots from these were analyzed by MALDI-TOF mass spectrometry and 28 proteins were identified. Most of the cytosolic proteins expressed at higher levels were found in P. polymyxa E681 cells grown in the presence of barley rather than in the absence of barley. Proteins detected at a lower level in the surpernatant of P. polymyxa E68l cells grown in the presence of barley were lipoprotein, glucose-6-phosphate 1-dehydrogenase, heat-shock protein HtpG, spermidine synthase, OrfZ, ribonuclease PH, and coenzyme PQQ synthesis protein, and flagellar hook-associated protein 2 whereas proteins detected at a higher level in the surpernatant of P. polymyxa E681 cells grown in the presence of barley included D-alanyl-D-alanine ligase A, isopentenyl-diphosphate delta-isomerase, ABC transporter ATP-binding protein Uup, lipase. Many of the proteins belonging to plant-induced stimulons are associated with biosynthetic metabolism and metabolites of proteins and transport. Some of these proteins would be expected to be induced by environmental changes resulting from the accumulation of plant-secreted substances.

• Journal of Microbiology and Biotechnology
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• 제18권8호
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• pp.1368-1376
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• 2008

In our previous study, the expression of active H-ferritins in Saccharomyces cerevisiae was found to reduce cell growth and reactive oxygen species (ROS) generation upon exposure to oxidative stress; such expression enhanced that of high-affinity iron transport genes (FET3 and FTR1). The results suggested that the recombinant cells expressing H-ferritins induced cytosolic iron depletion. The present study analyzes metabolic changes under these circumstances via proteomic methods. The YGH2 yeast strain expressing A-ferritin, the YGH2-KG (E62K and H65G) mutant strain, and the YGT control strain were used. Comparative proteomic analysis showed that the synthesis of 34 proteins was at least stimulated in YGH2, whereas the other 37 proteins were repressed. Among these, the 31 major protein spots were analyzed via nano-LC/MS/MS. The increased proteins included major heat-shock proteins and proteins related to endoplasmic reticulum-associated degradation (ERAD). On the other hand, the proteins involved with folate metabolism, purine and methionine biosynthesis, and translation were reduced. In addition, we analyzed the insoluble protein fractions and identified the fragments of Idh1p and Pgk1p, as well as several ribosomal assembly-related proteins. This suggests that intracellular iron depletion induces imperfect translation of proteins. Although the proteins identified above result from changes in iron metabolism (i.e., iron deficiency), definitive evidence for iron-related proteins remains insufficient. Nevertheless, this study is the first to present a molecular model for iron deficiency, and the results may provide valuable information on the regulatory network of iron metabolism.

• Journal of Chest Surgery
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• 제23권5호
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• pp.929-935
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• 1990

Violence in our society, combined with improving transport system, resulted in increased numbers of patients with cardiac wounds reaching the hospital alive. Most patients with penetrating cardiac injury, rather than blunt injury, present with a syndrome of either hemorrhagic shock or cardiac tamponade. And they should be operated upon as soon as possible. Often the atrioventricular valves and other important cardiac structures are also damaged by the penetrating instruments or missile. Both intracardiac communications and atrioventricular fistulas may result in significant left-to-right shunts accompanied by congestive heart failure, necessitating surgical correction. Usually, retained cardiac foreign bodies, which are almost always bullets or fragments of missiles, may lie within a cardiac chamber or in the myocardium. Emboli of bullets or other missiles from distant sites to the right side of the heart are numerous enough to require attention. Recently we experienced a case with intracardiac foreign body due to penetrating cardiac injury. A 19 year-old man was admitted to our hospital due to penetrating anterior chest wound by iron segment. The roentgenogram of the chest revealed a radio-opaque metallic shadow in left lower chest around the cardiac apex, mild blunting of left costophrenic space, but no cardiomegaly. During operation the foreign body was noted to be present in the cardiac chamber by the portable C-arm fluoroscopy. But during the manipulation it moved into left inferior pulmonary vein from left ventricle by way of left atrium. So we could manage to remove it from left inferior pulmonary vein by direct approach to the vein. It was iron segment, sized 0.lcm x0.6cmx0.5cm, with sharp margins. The patient had an uneventful postoperative recovery except for chylopericardium and was discharged.