• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.60-60
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• 2003

GSH-dependent glutaredoxinl (Grxl) was characterized in Dictyostelium discoideum. After starvation, the mRNA levels of grx1 gene increased during aggregation, thereafter decreased up to tip formation and increased again during culmination. To investigate the function of Grxl, the protein was overexpressed in D. discoideum using actinl5 promoter, The phenotype analysis on Grxl-overexpressed cells showed the maintenance of slug stage for a long period and delayed culmination under dark condition. To corroborate these phenotype by the enzyme, the two mutant forms of Grxl (C21S and C24S) were overexpressed in D. discoideum. The phenotype of two mutant cells represented no slug formation and the early culmination on dark condition. These results indicate that Grxl might regulate the transition from slug to culminant in darkness.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.18 no.12
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• pp.1301-1309
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• 2008

The curved portion fur each section running safety evaluation interpretation according to the track condition for improving the curved portion passage rate of a vehicle by using the multibody analysis model of the Saemaeul train was carried out. As a result, The excess of cant reaches the bad effect to the running safety in case the radius of curvature is small. In case the radius of curvature was large, we could confirm that the deficiency of cant reached the bad effect to the running safety. In the curved portion, the circular curve section most badly showed the running safety. The deficiency of curve length reaches the bad to the running safety. In the curved portion, the circular curve section most badly showed the running safety. Therefore the track condition(cant, transition curve length, etc) can reach the bad effect to the running safety of a vehicle, the exact design is required.

• Journal of the Korean Magnetic Resonance Society
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• v.27 no.1
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• pp.1-4
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• 2023

Transthyretin (TTR) is an indispensable transporter protein of thyroxine and a retinol molecule in humans. TTR has a stable homo-tetrameric structure in its native state, while upon dissociation into monomers, it becomes aggregation-prone and can form an amyloid fibril. Although the amyloidogenic propensity of TTR has been known and investigated since the late 1990s, the structural information regarding TTR's amyloidogenic species is still elusive. Here, we employed high-pressure nuclear magnetic resonance (HP-NMR) approaches on the monomeric variant of TTR (TTR[F87M/L110M]; M-TTR) and observed that it experiences a two-step transition in response to the pressurized condition. Our study demonstrated that M-TTR in an ambient condition has heterogeneous structural features, which is likely related to the amyloidogenic propensity of TTR.

• Journal of the Korean Geotechnical Society
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• v.31 no.9
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• pp.29-38
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• 2015

In this study, track dynamic interaction characteristics caused by the vehicle running through transitional section such as bridge abutments were studied using the finite element analysis program. The geometric condition of track was generated by trigonometric function and allowable maximum track irregularity is determined by KORAIL track maintenance criteria. The sub-infrastructure under rail fastener system was modelled by 3D solid elements. To reduce computational cost only half track line is numerically considered and the roller boundary condition was applied to each side of model. In this study, the vehicle-track dynamic interaction analysis was carried out for standard Korean transition section of concrete track and the dynamic behaviors were investigated. The dynamic characteristics considered are wheel load variation, vertical acceleration at body, and maximum Mises stress at each part of transitional section.

• Proceedings of the KIEE Conference
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• 2005.11b
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• pp.46-48
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• 2005

This paper discusses a probabilistic method for power system security assessment. The security analysis relates to the ability of the electric power systems to survive sudden disturbances such as electric short circuits or unanticipated loss of system elements. It consists of both steady state and dynamic security analyses, which are not two separate issues but should be considered together. In steady state security analysis including voltage security analysis, the analysis checks that the system is operated within security limits by OPF (optimal power flow) after the transition to a new operating point. Until now, many utilities have difficulty in including dynamic aspects due to computational capabilities. On the other hand. dynamic security analysis is required to ensure that the transition may lead to an acceptable operating condition. Transient stability, which is the ability of power systems to maintain synchronism when subjected to a large disturbance. is a principal component in dynamic security analysis. Usually any loss of synchronism may cause additional outages and make the present steady state analysis of the post-contingency condition inadequate for unstable cases. This is the reason for the need of dynamic studies in power systems. Probabilistic criterion can be used to recognize the probabilistic nature of system components while considering system security. In this approach. we do not have to assign any predetermined margin of safety. A comprehensive conceptual framework for probabilistic static and dynamic assessment is presented in this paper. The simulation results of the Western System Coordinating Council (WSCC) system compare an analytical method with Monte-Carlo simulation (MCS).

• Journal of Ocean Engineering and Technology
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• v.3 no.2
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• pp.125-137
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• 1989

To check technical improvement in the soundness and strength of 12% Cr steel rotor, a 25 tons of rotor with 65 tons of ingot was made in real size and was cut to pieces to take test samples, and the various mechanical tests such as impact, tensile, creep, and fatigue were carried out. The strengths are compared with those of 1% Cr-Mo-V rotor of same size. Microstructures of the samples are examined and reviewed. The results can be summarized as follows. 1) Fracture appearance transition temperatures are 80.deg. C at the center part and 60.deg. C near surface of 12% Cr rotor, and 8.deg. C near surface of 1% Cr-Mo-V rotor. 2) Comparative rapid softening occurs at higher temperatures above 600.deg. C for 12% Cr steel and 550.deg. C for 1% Cr-Mo-V steel in tension tests. 3) Fatigue crack propagation rate of 12% Cr steel is almost same as that of 1% Cr-Mo-V steel at the same corresponding surface part of the rotors. The crack growth rate of center part of 12% Cr rotor is faster than near surface part of the rotor, and the crack growth rate at the load condition of R=0.04 is slower than that of the load condition of R=0.5 for both 12% Cr steel and 1% Cr-Mo-V steel. 4) Crack growth rate of radial direction near surface of 12% Cr rotor is faster than that of transverse direction at the same part because of the difference in residual stresses. 5) Both creep and fatigue strengths of 12% Cr steel are superior to those of 1% Cr-Mo-V steel and the difference is thought the effect of climb and glide controlled creep by solid solution of alloying elements and dispersion of carbides.

• Journal of Ocean Engineering and Technology
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• v.3 no.2
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• pp.625-625
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• 1989

To check technical improvement in the soundness and strength of 12% Cr steel rotor, a 25 tons of rotor with 65 tons of ingot was made in real size and was cut to pieces to take test samples, and the various mechanical tests such as impact, tensile, creep, and fatigue were carried out. The strengths are compared with those of 1% Cr-Mo-V rotor of same size. Microstructures of the samples are examined and reviewed. The results can be summarized as follows. 1) Fracture appearance transition temperatures are 80.deg. C at the center part and 60.deg. C near surface of 12% Cr rotor, and 8.deg. C near surface of 1% Cr-Mo-V rotor. 2) Comparative rapid softening occurs at higher temperatures above 600.deg. C for 12% Cr steel and 550.deg. C for 1% Cr-Mo-V steel in tension tests. 3) Fatigue crack propagation rate of 12% Cr steel is almost same as that of 1% Cr-Mo-V steel at the same corresponding surface part of the rotors. The crack growth rate of center part of 12% Cr rotor is faster than near surface part of the rotor, and the crack growth rate at the load condition of R=0.04 is slower than that of the load condition of R=0.5 for both 12% Cr steel and 1% Cr-Mo-V steel. 4) Crack growth rate of radial direction near surface of 12% Cr rotor is faster than that of transverse direction at the same part because of the difference in residual stresses. 5) Both creep and fatigue strengths of 12% Cr steel are superior to those of 1% Cr-Mo-V steel and the difference is thought the effect of climb and glide controlled creep by solid solution of alloying elements and dispersion of carbides.

• The KIPS Transactions:PartA
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• v.9A no.3
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• pp.371-378
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• 2002

The EMFG (Extended Mark Flow Graph) is known as a graph model for representing the discrete event systems. In this paper, we introduce input/output matrixes representing the marking variance of input/output boxes when each transition fires in an EMFG, and compute an incidence matrix. We represent firing conditions of transitions to a firing condition matrix for computing a firable vector, and introduce the firing completion vector to decide completion of each transition’s firing. By using them, we improve an analysis algorithm of the EMFG’s operation to be represented all the process of EMFG’s operation mathematically. We apply the proposed algorithm to the system repeating the forward and reverse revolution, and then confirm that it is valid. The proposed algorithm is useful to analysis the variant discrete event systems.

• Nuclear Engineering and Technology
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• v.52 no.5
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• pp.925-936
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• 2020

To ascertain the characteristics of pool sloshing behavior that might be encountered during a core disruptive accident of sodium-cooled fast reactors, in our earlier work several series of experiments were conducted under various scenarios including the condition with mono-sized solid particles. It is found that under the particle-bed condition, three typical flow regimes (namely the bubble-impulsion dominant regime, the transitional regime and the bed-inertia dominant regime) could be identified and a flow-regime model (base model) has been even successfully established to estimate the regime transition. In this study, aimed to further understand this behavior at more realistic particle-bed conditions, a series of simulated experiments is newly carried out using mixed-size particles. Through analyses, it is verified that for present scenario, by applying the area mean diameter, our previously-developed base model can provide the most appropriate predictive results among the various effective diameters. To predict the regime transition with a form of extension scheme, a correction factor which is based on the volume-mean diameter and the degree of convergence in particle-size distribution is suggested and validated. The conducted analyses in this work also indicate that under certain conditions, the potential separation between different particle components might exist during the sloshing process.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2009.10a
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• pp.267-270
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• 2009

In the present investigation, we are newly developing a new forming process which can fabricate micro patterns on large-area polymeric substrates for high speed mass production. The key idea of the new process is to pressurize multiple vacuum-packed substrate-mold stacks above the glass transition temperature ($T_g$) of the polymeric substrates. The new process is thought to be promising micro-pattern fabrication technique in three aspects; firstly, isostatic pressing ensures the uniform micro-pattern replicating condition regardless of the substrate area. Secondly, the control of forming condition such as temperature and pressure can realize well-defined process condition exploited in the conventional hot embossing research field. Thirdly, multiple substrates can be patterned at the same time. A prototype forming machine for the new process was developed with the design consideration realizing the present idea. With a developed machine, micro prismatic array patterns with 50 um in size were successfully made on the $380{\times}300{\times}6\;mm$ PMMA plate.