• Title/Summary/Keyword: Trans-human

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A Study on the Dualism Appearing in the Modern Unisex Mode (유니섹스 모드에 반영된 Dualism에 관한 연구)

  • 이민경;한명숙
    • The Research Journal of the Costume Culture
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    • v.3 no.2
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    • pp.277-291
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    • 1995
  • The purpose of this study is to consider the internal meaning and the external from of Dualism in Unisex Mode : to investigate the dualistic expression appeared on the Unisex Mode by analyzing the general fashion magazine. The results of the study were as follows : First, the phenomenon of Dualism in Unisex Mode may be clues indication that some roles, once assigned exclusively to either males or females, are becoming mutually shared, or what may be called human roles. Second, the expression of Dualism in Unisex Mode whether direct away of symbolic way is represented by metaphoric manner such as unisex look(mono sex look, or trans sex look) with spirit of the time’s. Third, the formality and contents that related dualistic mode shows a various method in style, coordination of texture or item.

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Phenolic Constituents of Althaea rosea Canival. (접시꽃뿌리의 페놀성 성분)

  • Kim, Do-Hoon;Yang, Min-Cheol;Lee, Kyu-Ha;Kim, Ki-Hyun;Lee, Kang-Ro
    • Korean Journal of Pharmacognosy
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    • v.38 no.3 s.150
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    • pp.222-226
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    • 2007
  • Seven compounds, scopoletin (1), p-hydroxyphenethyl trans-ferulate (2), $1-({\alpha}-L-rhamnosyl(1\;{\rightarrow}\;6)-{\beta}-D-glucopyranosyloxy)-3,4,5-trimethoxybenzene$ (3), benzyl ${\alpha}-L-rhamnopyranosyl(1\;{\rightarrow}\;6)-{\beta}-D-glucopyranoside$ (4), suberic acid (5), sebacic acid (6) and scopolin (7) were isolated from the methanol extract of the roots of Althaea rosea Canival. Compounds $1\;{\sim}\;7$ were first isolated from this plant. The isolated compounds were tested for their cytotoxicity against human cancer cell lines using a SRB method in vitro.

Inhibition of C-terminal O-Methyltransferase by a Rat Liver Cytosolic Peptide

  • Park, Seung-Hee;Lee, Hyang-Woo
    • Archives of Pharmacal Research
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    • v.17 no.5
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    • pp.354-359
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    • 1994
  • The activity of SD-framesylcysteine O-methyltransferase was assayed by incubating the enzyrne with a synthetic in vitro substrate, [N-acetyl-S-trans, trns-famesyl-L-cysteine (AFC)], together with S-adenosyl-L-[emthyl-$_{14}$C)ester(AFCME)], was then analyzed either directly on HPLC or by converting the AFC[$methyl^{14}C$]ME to [$methyl^{14}C$] aclcohol by basehydrolysis. Employing these two analytical methods, it was established that a peptide purifed from rat liver cytosol fraction [Int. J. Biochem., 25, 1157 919930] strongly inhibited the above enzyme activity with $IC_{50}\; of\; 7.1\times 10^{-8}$ M. Also, the S-famesylcysteine O-methyltransferase from several human colon cancer cells was equally inhibited by the peptide.

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Triterpenes from Perilla frutescens var. acuta and Their Cytotoxic Activity

  • Woo, Kyeong Wan;Han, Ji Young;Choi, Sang Un;Kim, Ki Hyun;Lee, Kang Ro
    • Natural Product Sciences
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    • v.20 no.2
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    • pp.71-75
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    • 2014
  • Nine triterpenes were isolated from the petroleum ether and MeOH extract of Perilla frutescens var. acuta leaves. Their structures were determined to be arjunic acid (1), maslinic acid (2), oleanolic acid (3), euscaphic acid (4), tormentic acid (5), 3-O-trans-p-coumaroyltormentic acid (6), 28-formyloxy-$3{\beta}$-hydroxy-urs-12-ene (7), ursolic acid (8), and corosolic acid (9) by spectroscopic methods. The compounds 1, 2, 4, 6, and 7 were isolated for the first time from this plant and the Genus Labiatae. The isolated compounds (1-9) were tested for cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro using a Sulforhodamin B bioassay.

Pytochemical Constituents of the Aerial Parts from Solidago virga-aurea var. gigantea

  • Choi, Sang-Zin;Choi, Sang-Un;Lee, Kang-Ro
    • Archives of Pharmacal Research
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    • v.27 no.2
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    • pp.164-168
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    • 2004
  • The chromatographic separation of the MeOH extract of the aerial parts of Solidago virga-aurea var. gigantea $M_{IQ}$ . (Compositae) led to the isolation of six terpenoids and four phenolic compounds, trans-phytol (1), ent-germacra-4(15),5,10(14 )-trien-1$\alpha$-ol (2), $\beta$-amyrin acetate (3), ent-germacra-4(15),5,10(14)-trien-1$\beta$-ol (4), $\beta$-dictyopterol (5), oleanolic acid (6), kaempferol (7), kaempferol-3-O-rutinoside (8), methyl 3,5-di-O-caffeoyl quinate (9), and 3,5-di-O-caffeoyl quinic acid (10). Their structures were established by chemical and spectroscopic methods. Compounds 4, 5, and 10 showed moderate cytotoxicity against five cultured human tumor cell lines in vitro with its E $D_{50}$ values ranging from 1.52∼18.57 $\mu\textrm{g}$/mL.L.

Control of Rotary Inverted Pendulum using ANFIS (ANFIS를 이용한 수평회전형 도립진자의 제어)

  • Min, Hyun-Ki;Ryu, Chang-Wan;Ko, Joe-Ho;Yim, Wha-Yeong
    • Proceedings of the KIEE Conference
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    • 1998.07b
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    • pp.681-683
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    • 1998
  • Fuzzy Inference System is to trans late and be concrete with human expert in to mathematical equation. It is easy to be applied for Nonlinear System and the know ledge can be applied at that. With using the rule according to the Knowledge, when it is realized simulations must be required repeatedly and small vibration is generated in steady state, too. In this paper, we applied the system to the methodology of optimization with self-learn ing by us ing ANFIS(Adaptive Network-based Fuzzy Inference System) which makes use of back-propagation and least square method at a first order Sugeno Fuzzy System. In order to show the effect of Algorithm, we demonstrated it by us ing Rotary Inverted Pendulum.

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Resveratrol Impaired the Morphological Transition of Candida albicans Under Various Hyphae-Inducing Conditions

  • Okamoto-Shibayama, Kazuko;Sato, Yutaka;Azuma, Toshifumi
    • Journal of Microbiology and Biotechnology
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    • v.20 no.5
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    • pp.942-945
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    • 2010
  • The ability of the human fungal pathogen Candida albicans to undergo the morphological transition from a single yeast form to pseudohyphal and hyphal forms in response to various conditions is known to be important for its virulence. Many studies have shown the pharmacological effects of resveratrol, a phytoalexin polyphenolic compound. In this study, we investigated the antifungal activity of resveratrol against C. albicans. Both yeast-form and mycelial growth of C. albicans were inhibited by resveratrol. In addition, normal filamentation of C. albicans was affected and yeast-to-hypha transition under serum-, pH-, and nutrient-induced hyphal growth conditions was impaired by resveratrol.

Two New Lignans from Lindera obtusiloba Blume

  • Kwon, Hak-Cheol;Choi, Sang-Un;Lee, Jung-Ock;Bae, Ki-Hwan;Zee, Ok-Pyo;Lee, Kang-Ro
    • Archives of Pharmacal Research
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    • v.22 no.4
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    • pp.417-422
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    • 1999
  • Two new furanolignans (3, 5), together with three known lignans (1, 2, 4,), were isolated from the stem of Lindera obtusiloba (Lauraceae). The structures of the compounds were determined as actifolin (1), pluviatilol (2), 5,6-dihydroxymatairesinol (3), (+)-syringaresinol (4), and $(+)-9^{l}$-O-trans-feruloyl-5,51-dimethoxylariciresinol (5) on the basis of physicochemical and spectroscopic evidences. Compounds 1, 2, 3, and 5 showed cytotoxicity against a small panel of human tumor cell lines with values of $3.40{\sim}19.27 {\mu}g/ml$.

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Design and Performance Verification of Compound CVTs with 2K-H I type Differential Gear

  • Kim Yeon-Su;Park Jae-Min;Choi Sang-Hoon
    • Journal of Mechanical Science and Technology
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    • v.20 no.6
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    • pp.770-781
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    • 2006
  • This paper defined design constraints for the compound CVTs (continuously variable trans-missions) by combining power-circulation-mode CVTs and power-split-mode CVTs, which were proposed for connecting 2K-H I-type differential gear to V-belt-type CVU (Continuously Variable Unit). The design constraints are the necessary and sufficient conditions to avoid geometrical interferences among elements in the compound CVTs, and to guarantee smooth assembly between the power-circulation-mode CVT and power-split-mode CVT Two com-pound CVTs were designed and manufactured in accordance with the design constraints. With these compound CVTs, theoretical analysis and performance experiments were conducted. The results showed that the design constraints were valid and effective design method, and that the designed compound CVTs had the improved performance.

Product Studies by HPLC on the Hydrolysis of the anti- and syn-Tetrahydrodiol Epoxides and the 1,2-Tetrahydro Epoxide of Naphthalene

  • 이용태;Jed F. Fisher
    • Bulletin of the Korean Chemical Society
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    • v.18 no.8
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    • pp.856-860
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    • 1997
  • The arene epoxides from naphthalene, 1β,2α-dihydroxy-3α,4α-epoxy- (1) and 1β,2α-dihydroxy-3β,4β-epoxy-1,2,3,4-tetrahydronaphthalene (2) (anti- and syn-diol epoxide), 1,2-epoxy-1,2,3,4-tetrahydronaphthalene (3), and 1,2-epoxy-l,2-dihydronaphthalene (4), are model compounds of the ultimate carcinogenic metabolites of polycyclic aromatic hydrocarbons, ubiquitous environmental pollutants which may be causal in several human cancers. The product distribution in the hydrolysis of 1-4 have been studied by HPLC analysis of reaction mixtures. The yields of the trans product from the hydronium-ion-catalyzed and pH-independent hydrolysis in 9 : 1 (v/v) 20 mM buffer-dioxane at 25 ℃, respectively, were; 1: 98, 100; 2: 74, 87, 3: 95, 97, 4:100, 100. The results were rationalized by conformational equilibria of the epoxides and the carbocationic and zwitterionic intermediates from the epoxides.