• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3941-3944
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• 2015

Background: Aberrant expression of HOX gene expression has been observed in cancer. The purpose of this study was to investigate the alteration of HOXA5 and HOXA9 expression and their clinical significance in acute meloid leukemia (AML). Materials and Methods: The expression of HOXA5 and HOXA9 genes of bone marrow samples from 75 newly diagnosed AML patients and 22 healthy controls for comparison were examined by Real-time quantitative PCR (RQ-PCR) assay. Statistical analysis was conducted to evaluate HOXA5 and HOXA9 expression as possible biomarkers for AML. Results: The results showed that the complete remission rate (52.6%) of the patients who highly expressed HOXA5 and HOXA9 was significantly lower than that (88.9%) in patients who lowly express the genes (P=0.015). Spearmann correlation coefficients indicated that the expression levels for HOXA5 and HOXA9 genes were highly interrelated (r=0.657, P<0.001). Meanwhile, we detected significant correlations between HOXA9 expression and age in this limited set of patients (P=0.009). Conclusions: The results suggest a prognostic impact of increased expression of HOXA5 and HOXA9 in AML patients.

• Journal of the Korean Society of Clothing and Textiles
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• v.29 no.9_10 s.146
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• pp.1265-1273
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• 2005

The objective of this study is to examine the images of the current uniforms and to provide the basic references in designing female flight attendants uniforms. In Incheon International Airlines, 11 of the major airlines with the most passengers along with the highest capacity were chosen and 22 pieces of photographs were collected, two photos coming from each airline companies. The semantic differential scale has been formed by 16 pairs of adjectives. Then, it has conducted a statistical analysis using a SPSS WINDOWS that contains 475 copies of the selected questionnaires (375 of the non-flight attendants, and 100 of the female flight attendants). The following are the results and the conclusion of this study. According to this study, four main components of the uniforms of the female flight attendants were attractiveness, femininity, noticeability, and activity, which have occupied $65.9\%$ of the total variance. It was concluded that attractiveness and femininity were two main factors in perceiving the females' uniforms. According to the results of the uniform image difference, it was shown that Asiana Airline's uniform is the most attractive and Cathay Pacific Airline uniform is the most feminine. The most noticeable uniform was from Singapore airline which included cultural and traditional components of its own national colors. Pants suits of Lufthansa airline and Northwest airline were shown as the most active uniforms. There were significant differences in uniform images according to subjects' gender, age, education, and occupation. Men perceived uniforms more attractive, feminine, and active than women. People over 40 perceived uniforms more attractive, feminine, and active, and the High School graduates perceived uniforms more feminine and active. On occupational basis, Federal workers and Educators perceived uniforms more active on uniforms. Passengers who take planes once a month perceived uniforms more attractive, feminine, and active.

• Journal of Environmental Impact Assessment
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• v.8 no.3
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• pp.35-47
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• 1999

The purpose of this study is to research the environmental amenity factors of a city to devise the strategies to preserve the factors. For this study, the area of Masan city in Korea was chosen, and questionnaires, field studies, and statistical researches were used. Based on the results, the research showed the city surveyed had expanded by 1,069%, and the population of the city had increased by 272% from 1970 to 1995. In the city-life environment, the traffic was not smooth and the streets were not safe. The number of cars increased by 40,797% from 1970 to 1995, but the total length of roads increased only by 333%. The number of traffic accidents increased by 850%. Buildings were not preserved or maintained and did not have any traditional value. Additionally, buildings were not harmonious with environmental surroundings. Land allocation for utilization was not mixed well with tradition. In relation with the surroundings, there were not enough spaces for old people, and parking spaces were limited. In the field of public policy and finance, economic support and fundamental facilities were not enough. The survey of the household environment and the neighborhood environment showed that the room temperature, sunshine, air condition, and space were medial in the household environment. Public social facilities and entertainment culture had the lowest quality in the neighborhood environment. The city-life environment, the neighborhood environment, and the household environment affected the quality of life in order. The above results showed that cities should be planned upon sustainable development with the idea of emphasizing ecological harmony and considering people first, that citizen should be planned upon sustainable life by the harmony between people and the environment. Cities should be places where all people can live together pleasantly and cooperate with each other.

• The Journal of Internal Korean Medicine
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• v.34 no.2
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• pp.192-203
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• 2013

Objectives : To investigate the incidence of drug-induced liver injury (DILI) by combined-prescription of Korean herbal medicine (KHM; prescribed herbal medicine by doctors of traditional Korean medicine) and Western medicine on liver function. Methods : Sixty-nine in-patients who took KHM and Western medicine for various conditions were enrolled for prospective observational study. All subjects were given liver and renal function tests at the start of hospitalization to establish a baseline. After taking KHM and Western medicine, tests were done at approximately 4-week intervals afterwards. Results : Fifty-three subjects showed normal liver function test (LFT) at baseline, 50 subjects (72.5%) remained within the normal range at the second test, while 3 subjects (4.3%) tests revealed slight increase of LFT. However not a single patient had a high enough raised LFT to indicate liver injury. Sixteen of 69 subjects had abnormal baseline, 11 subjects recovered to normal levels and 5 subjects remained at abnormal level. Among all subjects, there was no statistically significant increase in LFT level between the first and second tests. Conclusions : This study shows that the combined-prescription of KHM and Western medicine did not cause any DILI. In some cases, combined treatment increased LFT levels but those increases were not high enough to have statistical significance. Additional large scale and systematical studies are required for more conclusive proof and results.

• The Korean Journal of Applied Statistics
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• v.18 no.3
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• pp.533-541
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• 2005

We identify the correct chromosome and locate the corresponding markers close to the QTL in the linkage analysis of a quantitative trait by using the SSVS method. We consider several markers linked to the QTL, as well as to each oyher and thus the i.b.d. values at these loci generate collinear predictors to be evaluated when using the SSVS approach. The results on considering only closely linked markers to two QTL simultaneously showed clear evidence in favor of the closest marker to the QTL considered over other markers. The results of the analysis of collinear markers with SSVS showeed high concordance to those obtained using traditional multiple regression. We conclude based on this simulation study that the SSVS is quite useful to identify linkage with multiple linked markers simultaneously for a complex quantitative trait.

• The Korean Journal of Applied Statistics
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• v.27 no.6
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• pp.1017-1028
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• 2014

Well-known Bayes and empirical Bayes estimators have a disadvantage in respecting to overshink the parameter estimator error; therefore, a constrained Bayes estimator is suggested by matching the first two moments. Also traditional loss function such as mean square error loss function only considers the precision of estimation and to consider both precision and goodness of fit, balanced loss function is suggested. With these reasons, constrained Bayes estimators under balanced loss function is recommended for non-life insurance pricing.; however, most studies focus on the performance of estimation since Bayes risk of newly suggested estimators such as constrained Bayes and constrained empirical Bayes estimators under specific loss function is difficult to derive. This study compares the Bayes risk of several Bayes estimators under two different loss functions for estimating the risk in the auto insurance business and indicates the effectiveness of the newly suggested Bayes estimators with regards to Bayes risk perspective through auto insurance real data analysis.

• The Korean Journal of Applied Statistics
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• v.23 no.5
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• pp.845-855
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• 2010

Extensively used case-control designs in medical studies can also be powerful and efficient for family association studies as long as an analysis method is developed for the evaluation of association between candidate genes and disease. Traditional Cochran-Armitage trend test is devised for independent subjects data, and to apply this trend test to the biologically related siblings one has to take into account the covariance among related family members in order to maintain the correct type I error rate. We propose a more powerful trend test by introducing weights that reflect the number of affected siblings in families for the evaluation of the association of genetic markers related to the disease. An application of our method to a sample family data, in addition to a small-scale simulation, is presented to compare the weighted and unweighted trend tests.

• Korean Journal of Applied Biomechanics
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• v.21 no.1
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• pp.25-29
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• 2011

The purpose of this study was to analyze quantitative and qualitative differences according to shoe type for the grand jete landing in ballet. The subjects for this study were 9 female ballet majors with an average of 12 years of experience. Subjects jumped, performing a front split, and landed on 1 foot, a movement called the grand jete. Analysis was performed on the students' landing. Independent variables were 3 shoe types: split sole, traditional out sole, and 5-toed forefoot shoes, with bare feet as a control group. Dependent variables were vertical passive ground reaction force and qualitative elements. Passive ground reaction force variables(maximum passive peak value, number of passive peaks, passive force-time integral, and center of pressure) were measured by the Kistler 9281B Force Platform. Qualitative elements were comfort, cushioning, pain, and fit. Statistical analysis included both 1-way ANOVA and Tukey's test for follow-up. Finalized data demonstrated that the 5-toed forefoot shoe allows the forefoot to expand and the toes to individually press down upon landing, increasing foot contact with the surface. Five-toed forefoot shoes minimize passive peaks and pain, while increasing comfort, cushioning, and fit. Most ballet movements are composed of jumping, balancing, landing, and spinning. Wearing 5-toed forefoot shoes allows for a natural range of movement in each toe, to improve both technique and balance. Pain and injuries from ballet can be minimized by wearing the correct shoe type. According to this analysis, it is possible to customized ballet shoes to increase the efficiency of techniques and movements.

• The Journal of Korean Society for School & Community Health Education
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• v.21 no.3
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• pp.35-47
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• 2020

Objectives: This study is a descriptive research study conducted to grasp the Prediction factors of the sexual violence experience of college students. Methods: A convenience sampling was performed for 500 students from one college located in Gyeongsangbuk-do, who agreed to the purpose of this study. Data collection was conducted from October 5, 2015, to October 23, 2015, by filling out the self-report questionnaire. Among the 450 subjects excluding those with missing values, a questionnaire of dating violence experience was applied to 317 college students who answered that they had a friend of the opposite sex, and variables and prediction factors related to dating violence experiences were identified. The statistical methods used were descriptive statistics, x²-test, t-test, Pearson's correlation coefficient and binary logistic regression analysis. Results: As a result of the study, the experience of sexual behavior before entering college (𝑥²=6.52, p=.011), experience of sexual violence damage before entering college(p=.045), the experience of sexual assault before entering college (p=.007) and experience of school violence damage(p=.002) were variables related to the sexual violence experience of college students. School violence victimization (OR=4.831, p=.007) and controlling dating partners (OR=1.349, p<.001) were predictors of dating sexual violence. Dating sexual violence experience group were compared to dating sexual violence non-experience group, the relative degree of controlling dating partners was high (t=4.25, p<.001) and had a traditional gender role attitude (t=2.94, p=.004). and there was a positive correlation (r=.358, p<.001) between controlling dating partners and gender role attitude. Conclusions: In order to prevent sexual violence on dating among college students, it is expected that more effective health education results will emerge if the contents of the school-age school violence victimization experience and the control of dating partners, which are predicted factors of sexual violence on dating, are included in the sexual violence prevention program.

• Journal of Korea Game Society
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• v.9 no.6
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• pp.31-44
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• 2009

BCI (Brain-Computer Interface) is a way to control computer by using the human brain waves. As the hardware using brain wave technologies has developed, former expensive and big sized brain wave measuring devices have recently become much smaller and cheaper in their prices, making it possible for the individuals to buy them. This predicts them to be applied in various fields of multimedia industry. This thesis is to give an insight into whether the BCI device can be used as a new gaming device approaching it in a game designing point of view. At first, we proposed game play elements that can effectively utilizing the BCI devices, systematize, and produced a game prototype adopting the BCI device based on such game play elements. Next, we verified it with statistical data analysis to show that the prototype adopting the BCI device gives more clear and efficient controls in its game play than a game of only adopting keyboard & mouse devices and analysis verified that BCI-based game play elements provide users with a more intuitive and interesting experience than traditional non-BcI-based game play elements. The results will give a guideline for effective game design methodology for making BCI based games.