• Tuberculosis and Respiratory Diseases
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• 제64권3호
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• pp.206-209
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• 2008

기관지결핵에 의한 기도폐쇄, 협착은 기관지결핵 치료 초기보다는 치료 도중 또는 치료 후기에 주로 발생하는 합병증이다. 23세 여자환자가 기관결핵을 진단받고 항결핵제 치료 시작 2주 후 급성으로 악화된 심한 기침, 호흡곤란으로 병원에 왔다. 시행한 기관지내시경에서 용종과 같은 기관종괴가 기관 내에서 호흡에 따라 상, 하 운동을 하면서 호기 시에 기도폐쇄를 일으켰고 이 종괴는 기관지 내시경을 통해 성공적으로 제거되었다. 기관결핵의 치료경과 중 발생한 드물게 보이는 형태의 급성 기도폐쇄로 사료되어 문헌고찰과 함께 보고한다.

• Biomolecules & Therapeutics
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• 제10권4호
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• pp.281-286
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• 2002

In this study, we intended to get a preliminary data for establishing rat tracheal surface epithelial(RTSE) cell culture system as an experimental model for physiology and pharmacology of tracheal epithelial cells. Primary culture on the membrane support and application of the air-liquid interface system at the level of cell layer were performed. The cell growth rate and mucin production rate were measured according to the days in culture. The results were as follows: this culture system was found to manifest mucocilliary differentiation of rat tracheal epithelial cells, the cells were confluent and the quantity of produced and released mucin was highest on culture day 9, the mucin was mainly released to the apical side and tbe free $^3{H}$-glucosamine which was not incorporated to process of synthesis of mucin was left on the basolateral side. Taken together, we suggest that air-liquid interface culture system can be used as a substitute for immersion culture system and as an experimental model for in vivo mucus-hypersecretory diseases.

• Tuberculosis and Respiratory Diseases
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• 제50권4호
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• pp.499-503
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• 2001

저자들은 7년 전 난소암으로 치료받고, 최근 호흡곤란이 발생하여 기관지 천식으로 오인된 환자가 흉부전산화단층촬영과 기관지내시경, 경기관지 조직검사를 통해 난소암으로부터 전이된 기관 종양으로 진단받은 1예를 경험하였기에 보고하는 바이다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4447-4450
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• 2015

Background: Nasopharyngeal cancer is a disease with distinct ethnic and geographical distribution. The aim of this review was to describe the epidemiological characteristics of nasopharyngeal cancer in Iran from 2004 to 2009 because no systematic study has been performed to evaluate the trends of its incidence yet. Materials and Methods: The data were derived from the databases of the National Cancer Data System Registry in the period of 2004-2009. Nasopharyngeal cancers were classified according to the International Classification of Diseases for Oncology. Incidence rates and trends were calculated and evaluated by gender, age decade, and histopathology types. Results: A total of 1,637 nasopharyngeal cancers were registered in Iran from 2004 to 2009 giving an incidence of 0.38 per 100,000. The male-to-female ratio was 2.08:1. The trend of incidence was found to have increased, with a significant increase observed in males. Undifferentiated carcinoma was the most common histopathology type in all the age decades. Conclusions: Because the incidence of nasopharyngeal cancers in Iran has increased, especially in males, further studies are recommended for understanding of the etiological factors involved in the rise of the disease.

• Tuberculosis and Respiratory Diseases
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• 제45권3호
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• pp.583-586
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• 1998

기관성 기관지는 기관분기부 상부의 기관에 이소성 기관지가 존재하는 기관지 기형으로 대부분 특별한 증상없이 기관지내시경검사 혹은 기관지조영술시에 우연히 발견되고 특별한 치료가 필요 없다. 그러나 반복적인 폐렴, 기관지확장증 등이 동반된 경우에는 수술적 치료가 필요하다.

• Tuberculosis and Respiratory Diseases
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• 제77권5호
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• pp.215-218
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• 2014

Tracheal invasion is an uncommon complication of thyroid cancer, but it can cause respiratory failure. A rigid bronchoscope may be used to help relieve airway obstruction, but general anesthesia is usually required. Tracheal balloon dilatation and stent insertion can be performed without general anesthesia, but complete airway obstruction during balloon inflation may be dangerous in some patients. Additionally, placement of the stent adjacent to the vocal cords can be technically challenging. An 86-year-old female patient with tracheal invasion resulting from thyroid cancer was admitted to our hospital because of worsening dyspnea. Due to the patient's refusal of general anesthesia and the interventional radiologist's difficulty in completing endotracheal stenting, we performed endotracheal tube balloon dilatation and argon plasma coagulation. We have successfully treated tracheal obstruction in the patient with thyroid cancer by using endotracheal tube balloon inflation and a flexible bronchoscope without general anesthesia or airway obstruction during balloon inflation.

• Journal of Chest Surgery
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• 제49권5호
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• pp.405-407
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• 2016

Tracheal diverticulum is often diagnosed incidentally and, due to its rarity, there is no standard treatment. It is a benign entity, but has the potential to cause specific symptoms, such as chronic upper respiratory infection and chronic cough. Symptomatic tracheal diverticulum can be medically treated, but likelihood of recurrence is high. We report a case of surgical resection of symptomatic tracheal diverticulum to prevent recurrence.

• Tuberculosis and Respiratory Diseases
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• 제53권4호
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• pp.450-456
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• 2002

심한 호흡부전을 보인 특발성 기관 협착증 환자에서 풍선 확장술 및 기관 스텐트 삽입술을 시행하여 호흡을 안정시킨 후 수술적 절제 및 문합술을 시행하였다.

• Tuberculosis and Respiratory Diseases
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• 제38권1호
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• pp.8-15
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• 1991

It has been well known that the integrity of airway epithelium is important in development of bronchial hyperreactivity and bronchial asthma. But the mechanisms involved are still unclear. To evaluate that airway epithelium is able to modulate the contraction of guinea pig tracheal smooth muscle, we investigated the responsiveness of intact and epithelium-denuded tracheal strips to histamine and acetylcholine. And to evaluate whether cyclooxgenase products play a role in this modulatory mechanism, we also investigated the effect of indomethacin pretreatment on the tracheal responsiveness to histamine. Results were as follows: 1) In guinea pig tracheal smooth muscle the presence of airway epithelium significantly reduced the response to histamine. 2) In the presence of indomethacin dose-response curves and $EC_{50}$ values were similar between intact and epithelium-denuded tracheal strips, that is, indomethacin abolished the influence of epithelium on the contracion of tracheal smooth muscle. 3) The response of tracheal smooth muscle to acetylcholine was similar both in the presence and absence of epithelium. These results suggest that airway epithelium of guinea pig may generate an inhibitory signal to decrease the response of tracheal smooth muscle to histamine and cyclooxygenase products may contrbute to the modulation of airway epithelium on the contracion of tracheal smooth muscle.

• 대한기관식도과학회지
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• 제3권1호
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• pp.148-153
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• 1997

Laryngotracheal stenosis is one of the most troublesome diseases in the Em field. Subglottic stenosis can be treated by a cricoid augmentation with rib cartilage. In case of tracheal stenosis, the treatment of choice is by tracheal end-to-end anastomosis after resection of the stenotic site. However, in case of subglottic stenosis combined with tracheal stenosis, it is hard to manage. Even though several methods(such as thyrotracheal anastomosis) have been tried, they have some limitations too much excision of normal trachea and too much pulling up of the trachea after resection of the stenotic lesion. The authors have managed two cases of laryngotracheal stenosis as an anterior and posterior subglottic augmentation with an autologous cartilage graft and laryngotracheal anastomosis. The first few weeks after the operation, we could do a decannulation successfully, but in one case the patient developed restenosis. Even though one case was unsuccessful, the authors believe that this method could be used in the treatment of laryngotracheal stenosis.