• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.2
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• pp.90-96
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• 2018

Tracer experiments were carried out on two laboratory modes, "without media mode" and "with media mode", to examine the hydraulic characteristics of the anaerobic fluidized bed bioreactor (AFBR). For both configurations, a formula was derived for the hydraulics and data interpretation to obtain the actual characteristics of the reactor. The dispersion model is based on the assumption that carriers are non-reacting and the dispersion coefficient is constant. The model represents the one-dimensional unsteady-state concentration distribution of the non-reacting tracer in the reactors. The experimental results showed that the media increased the mixing conditions in the reactor considerably. For the reactor without media, in the range tested, the dispersion coefficient was at least an order of magnitude smaller than that of the reactor with media. Advective transport dominates and the flow pattern approaches the plug flow reactor (PFR) regime. The dispersion coefficient increased significantly as us, the superficial liquid velocity, was increased proportionally to 0.82cm/s. On the other hand, for the reactor with media, the flow pattern was in between a PFR and a completely mixed flow reactor (CMFR) regime, and the dispersion coefficient was saturated at us=0.41cm/s, remaining relatively constant, even at us=0.82cm/s. The dispersion coefficient depends strongly on the liquid Reynolds number (Re) or the particle Reynolds number (Rep) over the range tested.

• Journal of The Korean Society of Agricultural Engineers
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• v.59 no.6
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• pp.61-71
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• 2017

The tracer gas method has an advantage that can estimate total and local ventilation rate by tracing air flow. However, the field measurement using tracer gas has disadvantages such as danger, inefficiency, and high cost. Therefore, the aim of this study was to evaluate ventilation rate in pig house by using the thermal distribution data rather than tracer gas. Especially, LMA (Local Mean Age), which is an index based on the age of air theory, was used to evaluate the ventilation rate in pig house. Firstly, the field experiment was conducted to measure micro-climate inside pig house, such as the air temperature, $CO_2$ concentration and wind velocity. And then, LMA was calculated based on the decay of $CO_2$ concentration and air temperature, respectively. This study compared between LMA determined by $CO_2$ concentration and air temperature; the average error and root mean square error were 3.76 s and 5.34 s. From these results, it was determined that thermal distribution data could be used for estimation of LMA. Finally, CFD (Computational fluid dynamic) model was validated using LMA and wind velocity. The mesh size was designed to be 0.1 m based on the grid independence test, and the Standard $k-{\omega}$ model was eventually chosen as the proper turbulence model. The developed CFD model was highly appropriate for evaluating the ventilation rate in pig house.

• The Korean Journal of Nuclear Medicine Technology
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• v.20 no.2
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• pp.62-68
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• 2016

Purpose In a cyclosporine experiment using a robotic liquid handing system has found a deviation of its standard curve and low reproducibility of patients's results. The difference of the test is that methanol is mixed with samples and the extractions are used for the test. Therefore, we assumed that the abnormal test results came from using methanol and conducted this test. In a manual of a robotic liquid handling system mentions that we can choose several setting parameters depending on the viscosity of the liquids being used, the size of the sampling tips and the motor speeds that you elect to use but there's no exact order. This study was undertaken to confirm pipetting ability depending on types of liquids and investigate proper setting parameters for the optimum dispensing ability. Materials and Methods 4types of liquids(water, serum, methanol, PEG 6000(25%)) and $TSH^{125}I$ tracer(515 kBq) are used to confirm pipetting ability. 29 specimens for Cyclosporine test are used to compare results. Prepare 8 plastic tubes for each of the liquids and with multi pipette $400{\mu}l$ of each liquid is dispensed to 8 tubes and $100{\mu}l$ of $TSH^{125}I$ tracer are dispensed to all of the tubes. From the prepared samples, $100{\mu}l$ of liquids are dispensed using a robotic liquid handing system, counted and calculated its CV(%) depending on types of liquids. And then by adjusting several setting parameters(air gap, dispense time, delay time) the change of the CV(%)are calcutated and finds optimum setting parameters. 29 specimens are tested with 3 methods. The first(A) is manual method and the second(B) is used robotic liquid handling system with existing parameters. The third(C) is used robotic liquid handling system with adjusted parameters. Pipetting ability depending on types of liquids is assessed with CV(%). On the basis of (A), patients's test results are compared (A)and(B), (A)and(C) and they are assessed with %RE(%Relative error) and %Diff(%Difference). Results The CV(%) of the CPM depending on liquid types were water 0.88, serum 0.95, methanol 10.22 and PEG 0.68. As expected dispensing of methanol using a liquid handling system was the problem and others were good. The methanol's dispensing were conducted by adjusting several setting parameters. When transport air gap 0 was adjusted to 2 and 5, CV(%) were 20.16, 12.54 and when system air gap 0 was adjusted to 2 and 5, CV(%) were 8.94, 1.36. When adjusted to system air gap 2, transport air gap 2 was 12.96 and adjusted to system air gap 5, Transport air gap 5 was 1.33. When dispense speed was adjusted 300 to 100, CV(%) was 13.32 and when dispense delay was adjusted 200 to 100 was 13.55. When compared (B) to (A), the result increased 99.44% and %RE was 93.59%. When compared (C-system air gap was adjusted 0 to 5) to (A), the result increased 6.75% and %RE was 5.10%. Conclusion Adjusting speed and delay time of aspiration and dispense was meaningless but changing system air gap was effective. By adjusting several parameters proper value was found and it affected the practical result of the experiment. To optimize the system active efforts are needed through the test and in case of dispensing new types of liquids proper test is required to check the liquid is suitable for using the equipment.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.2
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• pp.45-49
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• 2010

Purpose: Several radiopharmaceuticals were used for cisternography. But recently, due to more short acquisition time, high resolution than other radiopharmaceuticals like In-111 DTPA, we were using Tc-99m DTPA in cisternography. Using of Tc-99m DTPA for intrathecal, was not officially recognised by the FDA. And there are matters of aseptic meningitis, muscular tetany, seizures by inappropriate radiopharmaceuticals handling. So, it is necessary to prevent adverse reactions while handling the radiopharmaceuticals using in cisternography. Therefore, this study aims to evaluation of usefulness and procedures for safety of radiopharmaceuticals in cisternography. Materials and Methods: Subjects were 12radioactive tracer vials using in cisternography in 2008 Dec. 16 - 2009 Dec. 30. (1) Radioactive tracer Vial test - We were measured NaPertechnetate radiation dose and volume, normal saline volume for dilution, source volume and dose activity for patient injection. And then, calculated mass of pure DTPA. (2) Bacterial endotoxin test - We performed pyrogen test using by negative/positive control vials which was added normal saline 0.2 mL and added normal saline 0.1 mL, Tc-99m DTPA 0.1 mL in test control vial. And then, reacted by digital hot plate in $37.5^{\circ}C$ for 1 hour and compared of gel-clot in each control vials. (3) Compliance safety procedure - We were checked safety issues and wrote out a safety procedure exam sheet. Results: (1) Radioactive tracer Vial test - Mass of DTPA per dose for patient injection (mg) was 0.88 (mg) on average, and Mass of DTPA per volume for patient injection (mg) was 0.74 (mg) on average. (2) Bacterial endotoxin test - All control test vials showed negative reactions. (3) Compliance safety procedure - We were checked safety issues and wrote out a safety exam sheet in all the exams. So, there were no adverse reactions. Conclusion: We could examine easier to safety tests using by Techscan - DTPA (Mallinckrodt): CaNa3. Each test results were passed the safety tests and there are no adverse reactions. The use of Tc-99m DTPA for cisternography, always has been become an issue. Since it has occur adverse reaction while examine the cisternography using by Tc-99m DTPA, it needs to set up the 'Standard Operating procedures'.

• 한국가시화정보학회:학술대회논문집
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• 2001.12a
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• pp.100-107
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• 2001

A simple new technique of particle depth position measurement, which can be applied for three-dimensional velocity measurement of fluid flows, is proposed. Two color illumination system that intensity is encoded as a function of z-coordinate is introduced. A calibration procedure is described and a profile of small sphere is detected by using the present method as preliminary test. Then, this method is applied to three-dimensional velocity field measurement of simple flow fields seeded with tracer particles. The motion of the particles is recorded by color 3CCD camera. The particle position in the image plane is read directly from the recorded image and the depth of each particle is measured by calculation of the intensity ratio of encoded two color illumination. Therefore three-dimensional velocity components are reconstructed. Although the result includes to some extent error, the feasibility of the present technique for three-dimensional velocity measurement was confirmed.

• Journal of the Korean Society for Precision Engineering
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• v.17 no.5
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• pp.131-136
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• 2000

This paper is concerned with the surface roughness and the bending strength of ground workpiece in ZrO2 ceramic grinding. Surface roughness was measured with surface tracer and bending strength value was obtained by three-point bending test on machining center using tool dynamometer. Grinding experiments were carried out to examine the effects of grinding conditions including diamond mesh size, table speed, and depth of cut on ground surface roughness. The correlation between surface roughness and bending strength was also inspected. The experimental results indicate that the rougher surface is produced as the mesh size of diamond wheel is reduced and table speed is increased, but surface roughness is not affected by depth of cut. The values of bending strength decrease as the values of Ra, Rmax and Ku increase.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2000.04a
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• pp.465-470
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• 2000

This paper is concerned with the surface roughness and the bending strength of ground workpiece in ZrO2 ceramic grinding. Surface roughness was measured with surface tracer and bending strength value was obtained by three-point bending test on machining center using tool dynamometer. Grinding experiments were carried out to examine the effects of grinding conditions including diamond mesh size, table speed, and depth of cut on ground surface roughness. The correlation between surface roughness and bending strength was also inspected. The experimental results indicate that the rougher surface was produced as the mesh size of diamond wheel is reduced and table speed is increased, but surface roughness is not affected by depth of cut. The values of bending strength decrease as the values of Ra, Rmax and Ku increase.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2003.04a
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• pp.268-271
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• 2003

연구지역에 설치된 3개 관정에서 추적자시험 방법 중 단공 주입-회수시험을 실시하였다. Push-pull 추적자시험 자료 분석 결과 종분산지수는 0.086~0.657m의 값을 가지며(Pickens and Grisak, 1981), 지하수 유동속도는 9.07$\times$$10^{-4}$6.14$\times$$10^{-3}$m/min의 값을 보인다(Hall and other, 1991). 또한 계산된 종분산지수와 지하수 유속을 이용하여 종분산계수(3.77$\times$$10^{-4}$ ~ 9.53$\times$$10^{-4}$ $m^2$/min)를 산정하였다. 추적자의 거동특성이 크고 작음을 비교할 수 있게 하는 특성변수(Characteristic property)는 분산지수이므로, 분산지수의 크고 작음에 따라서 추적자의 거동특성이 달라짐에 주의해야 한다..

• Proceedings of the Korea Water Resources Association Conference
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• 2004.05b
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• pp.409-413
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• 2004

자연하천에서의 횡혼합 특성을 분석하고 횡분산계수를 산정하기 위해서 추적자 실험을 실시하였다. 추적자 실험은 섬강에서 세번, 홍천강에서 두번, 청미천에서 한번, 총 여섯 군데에서 실행되었다. 각각의 실험에서 속도, 수심, 유속과 같은 수리량이 측정되었다. 추적자로서는 미량으로도 관측이 용이하며 병원에서 진찰용으로 사용할 만큼 인체에 해롭지 않은 방사성 동위원소 (I-131)를 사용하였다. 추적자 실험을 통해 얻어진 농도데이터와 수리량 데이터를 이용하여 횡분산계수를 산정하였으며 이때 모멘트 방법과 수정모멘트 방법 그리고 유관모형 추적법이 사용되었다. 세가지 방법을 이용하여 산정된 횡분산계수를 토대로 각각의 방법이 자연하천에서의 횡분산계수를 산정하는데 합당할지를 비교 분석하였다. 또한 여섯 경우의 지형이 다른 자연하천에서 구한 횡분산계수를 토대로 하천의 형상에 의해 하천에서의 횡분산 거동이 어떻게 달라지는가를 분석하였다.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2005.04a
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• pp.127-130
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• 2005

The feasibility of stimulating in situ aerobic cometabolic activity of indigenous microorganisms was investigated in a trichloroethene(TCE)-contaminated aquifer, A series of single-well natural drift tests (SWNDT) was conducted by injecting site groundwater amended with a bromide tracer and combinations of toluene, oxygen, nitrate, ethylene and TCE into an existing monitoring well and by sampling the same well over time. Transformation of ethylene, a surrogate of overall TCE transformation activity, was also observed, and its transformation results in the production of ethylene oxide, suggesting that some tolune-oxidizing microorganisms stimulated may express a monooxygenase enzymes. Also in situ transformation of TCE was confirmed by dilution-adjusted data analysis developed in this study. These results indicate that, in this environment, toluene and oxygen additions stimulated the growth and aerobic cometabolic activity of indigenous microorganisms expressing monooxygenase enzymes and that these are responsible for observed toluene utilization and cometabolism of ethylene and TCE. The simple, low-cost field test method provides an effective method for conducting rapid field assessments and pilot testing of aerobic cometabolism of TCE, which has previously hindered application of this technology to groundwater remediation.