• Journal of Pharmacopuncture
• /
• v.22 no.2
• /
• pp.109-114
• /
• 2019

Objectives: Oxidative stress plays a central role in diabetes-induced complications. In the present study, the protevtive effect of Artemisia turanica (A. turanica) was evaluated against diabetes-induced liver oxidative stress and dysfunction. Methods: Fifty male Wistar rats were randomly divided into five groups: control, diabetic, diabetic + metformin, diabetic + A. turanica extract, and diabetic + A. turanica extract + metformin. Experimental diabetes was induced by a single-dose (55 mg/kg, intraperitoneally (ip)) injection of streptozotocin (STZ). Metformin (300 mg/kg) and A. turanica extract (70 mg/kg) were orally administrated three days after STZ injection for four weeks. The levels of malondialdehyde (MDA), total thiol content and superoxide dismutase (SOD) and catalase activities were measured in the liver tissue. Serum glucose concentration, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities were also determined. Results: In the diabetic group, serum glucose concentration, serum AST and ALT activities and liver MDA level were significantly higher while tissue total thiol content as well as catalase and SOD activities were lower, compared to the control group. Serum glucose in diabetic rats treated with metformin + A. turanica extract showed a significant decrease compared with the diabetic group. In all the A. turanica extract and metformin treated groups, serum ALT, tissue MDA level, total thiol content and SOD activity significantly improved compared with the diabetic rats. However, treatment of the diabetic rats only with metformin could not significantly change the activities of catalase and AST compared with the diabetic group. Conclusion: These findings suggested that A. turanica extract had a therapeutic effect on liver dysfuncyion and oxidative stress induced by diabetes, that may be probably due to its antioxidant and antiinflammatory effects.

• Animal Bioscience
• /
• v.34 no.5
• /
• pp.844-854
• /
• 2021

Objective: The potential of extra virgin olive oil (EVOO), betaine (BET), and ginger (GIN), as natural antioxidants, in reducing negative effects of heat stress on physiological responses, antioxidant capacity, semen quality and fertility of bucks under heat stress were investigated. Methods: Forty adult Animal Production Research Institute line rabbit bucks were distributed randomly into four experimental treatments of ten rabbits each. The first treatment was fed the commercial pellet diet (CPD) without supplementation and served as a control. The other three treatments were fed CPD supplemented with EVOO (300 mg), BET (1,000 mg), and GIN (200 mg) per kg diet for 3 consecutive months during the summer season. Results: Supplementation of EVOO, BET, or GIN improved (p<0.05) the sexual desire, progressive motility, vitality, intact acrosome and membrane integrity, sperm cell concentration, sperm outputs and fertility. Seminal plasma total proteins, globulin, total antioxidant capacity, glutathione and glutathione S-transferase, and initial fructose increased (p<0.05), while total lipids, aspartate and alanine aminotransferases and malondialdehyde decreased (p<0.05) compared with the control. In comparing the natural antioxidants treatments, GIN evoked the largest improvement. Conclusion: The inclusion of GIN (200 mg/kg diet) appeared to improve the sexual desire, semen quality and oxidative stress of bucks. This may be a beneficial supplement for the management of rabbit bucks used in natural mating or artificial insemination.

• Korean Journal of Human Ecology
• /
• v.21 no.2
• /
• pp.213-223
• /
• 2012

The purpose of this study was to evaluate the relationship between stress, temperament and maternal-fetal attachment in pregnant women. The respondents in this research were 249 pregnant women who were participating in a Parent Education project. Data was collected by way of a questionnaire. A summary of the findings were as follows: Among the pregnant women in this study, total stress level was below the average and maternal fetal attachment level was above the average. The group demonstrating high levels of stress exhibited low level of maternal-fetal attachment when compared to those with low levels stress. Pregnant woman's stress and maternal temperament demonstrated a significant correlation with maternal-fetal attachment.

• Korean Journal of Occupational Health Nursing
• /
• v.19 no.2
• /
• pp.268-277
• /
• 2010

Purpose: To examine the relations among occupational satisfaction, stress, and customer orientation of upper-scale general hospital nurses. Method: We studied with structured questionnaires with total 66 questions for 218 nurses working at university hospitals in Gangwon-do from February 2 to 22, 2010. Result: Occupational satisfaction and customer-oriented character increased when nurses' ages and career experiences were higher, married, working in daytime without shift and in higher positions. Occupational stress increased when nurses were younger, not married, with three shifts, and when they were general nurses. However, there was no statistical difference. Customer-oriented character had positive correlation with occupational satisfaction and stress while occupational satisfaction had negative correlation(r=-0.358) with occupational stress. Conclusion: As occupational stress and satisfaction of nurses in university hospitals showed significant relations with customer-oriented character, t is necessary to reduce occupational stress of nurses, and strengthen occupational satisfaction of them.

• Women's Health Nursing
• /
• v.1 no.2
• /
• pp.244-259
• /
• 1995

This study was designed and carried out to describe the stress of the infertile women and identify its predictors. The subjects of this study, 131 infertile women, were in primary or secondary infertility. the were conveniently sampled out from the infertility clinics of K University Medical Center and C Hospital in Seoul. The data were collected by using the Infertility Stress Scale which consisted of 35 items with four dimensions(cognitive, affective, marital and social stress) from August to November 1994. The data were analyzed by using the pc-SAS program. The information was obtained of Mean, Standard Deviation, Frequencies, Percentile, t-test, ANOVA, Duncan's multiple comparison test and Multiple Regression. The results are as follows; 1. The Mean of the stress of the infertile women is 2.78. The Means of the stress in 4 dimensions are 3.81 in the cognitive dimension, 3.05 in the affective dimension, 2.06 in the marital adjustment dimension and 2.41 in the social adjustment dimension. 2. The predictors of the stress of the infertile women are their educational levels and subjective economic status. They explain 14.08% of total variance.

• Korean Journal of Adult Nursing
• /
• v.23 no.4
• /
• pp.397-402
• /
• 2011

Purpose: This study was designed to explore the relationship of depression with stress, anxiety and mindfulness in nursing students in 2010. Methods: A cross-sectional design was used and data was collected through structured questionnaires. Depression, stress, anxiety, and mindfulness were measured by using the Depression, Anxiety and Stress Scale (DASS) and the Mindfulness Attention Awareness Scale (MAAS). The data were analyzed using t-test, one-way ANOVA, Pearson correlation coefficient, and stepwise multiple regression. Results: A total of 131 nursing students participated in this study. Depression was positively associated with stress (r=.81, p<.001) and anxiety (r=.76, p<.001), and negatively associated with mindfulness (r=-.73, p<.001). Multiple regression analyses showed that in different type of residence, anxiety and mindfulness were statistically significant predictors of depression with explanatory power of 67%. Conclusion: When nurse instructors manage depression among nursing students, the strategies need to address stress, anxiety, and mindfulness. This study may help nursing students to better manage their depression.

• International Journal of Reliability and Applications
• /
• v.17 no.1
• /
• pp.21-49
• /
• 2016

Many mechanical, electrical and electronic products have more than one performance characteristics (PCs). For example the performance degradation of rubidium discharge lamps can be characterized by the rubidium consumption or the decreasing intensity the lamp. The product may degrade due to all the PCs which may be independent or dependent. This paper deals with the design of optimal bivariate step-stress partially accelerated degradation test (PADT) with degradation paths modelled by gamma process. The dependency between PCs has been modelled through Frank copula function. In partial step-stress loading, the unit is tested at usual stress for some time, and then the stress is accelerated. This helps in preventing over-stressing of the test specimens. Failure occurs when the performance characteristic crosses the critical value the first time. Under the constraint of total experimental cost, the optimal test duration and the optimal number of inspections at each intermediate stress level are obtained using variance optimality criterion.

• Research in Community and Public Health Nursing
• /
• v.27 no.2
• /
• pp.124-131
• /
• 2016

Purpose: The purpose of this paper was to identify the correlations among academic stress and adjustment at university life in university students. Methods: A total of 489 subjects aged 17 and 36 were selected through convenient sampling. Data were collected with a self reported questionnaire from September 2 to November 30, 2015. Collected data were analyzed with SPSS/WIN. Results: There were statistical differences between academic stress and adjustment at university life. Academic stress were significantly different according to gender, grade, economic status, health status major department of study, drinking and smoking. Adjustment at university life were significantly different according to gender, economic status, health status. 25.4% of variance in adjustment at university life were explained by academic stress, major department of study, health status. Conclusion: The finding of this study may be useful in understanding the academic stress expression of university students and developing more specific programs on adjustment at university life.

• Geomechanics and Engineering
• /
• v.12 no.3
• /
• pp.347-360
• /
• 2017

The problem of cylindrical cavity expansion incorporating deformation dependent of intermediate principal stress in rock or soil mass is investigated in the paper. Assumptions that the initial axial total strain is a non-zero constant and the axial plastic strain is not zero are defined to obtain the numerical solution of strain which incorporates deformation-dependent intermediate principal stress. The numerical solution of plastic strains are achieved by the 3-D plastic potential functions based on the M-C and generalized H-B failure criteria, respectively. The intermediate principal stress is derived with the Hook's law and plastic strains. Solution of limited expansion pressure, stress and strain during cylindrical cavity expanding are given and the corresponding calculation approaches are also presented, which the axial stress and strain are incorporated. Validation of the proposed approach is conducted by the published results.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 2002.05a
• /
• pp.195-198
• /
• 2002

Residual stress of sheet occurs during cold rolling and it is hard to avoid and inevitable. The residual stress in the sheet cause etching curls when it suffers peroration process. The residual stress through the thickness direction in the sheet is a function of a friction coefficient, total reduction, mil size and initial sheet thickness. To estimate the residual stress and deformation due to etching curl, FEM analysis is performed. A numerical analysis is used a ANSYS 5.6 and an elastic-plastic constitutive equations. rho simulation results indicate a distribution of residual stress.