• Applied Chemistry for Engineering
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• v.29 no.3
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• pp.325-329
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• 2018

In this study, polyphenols were extracted from Angelica, which are known to have a high antioxidant content and the extraction process was optimized using the response surface methodology. The extraction yield and the total polyphenols were set as response values for the methodology. Quantitative factors in the extraction process were the extraction time, volume ratio of alcohol/ultrapure water, and extraction temperature. When considering both the main and interaction effects, the greatest influence factor on the extraction yield and total polyphenols was the extraction time. The optimum extraction time and temperature and alcohol/ultrapure water volume ratio for angelica were 2.8 h, $56.6^{\circ}C$ and 64.0 vol% respectively. The extraction yield and total polyphenols when using the conditions were calculated to be 24.6% and 8.76 mg GAE/g. respectively. Determination coefficients of regression equations for the extraction yield and total polyphenols were 81.4 and 75.4%, respectively. Also the overall satisfaction level was found to be 0.80 and the significance was confirmed within 5%.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.17 no.7
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• pp.754-759
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• 2004

We have studied the fringe field switching (FFS) mode with the positive dielectric anisotropy for the fast response time. The factors such as the physical properties of the LC, the cell gap, and the rubbing angle were critical for the fast response time of the FFS mode. The response time became 10 ms faster when the rotational viscosity of the new LC is 20 mPa.s lower than the conventional LC. When the cell gap changed from 3.6 ${\mu}{\textrm}{m}$ to 3.0 ${\mu}{\textrm}{m}$, it was possible to achieve the total response time and response times associated with grey-to-grey transitions under 16 ms. And the response times including grey-to-grey transitions become fast as the rubbing angle decreases.

• Industrial Engineering and Management Systems
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• v.13 no.3
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• pp.297-303
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• 2014

Stock pre-positioning is one of the most important decisions for preparing the stage of emergency logistics planning. In this paper, a mixed integer model for stock pre-positioning is derived to support an emergency disaster relief response against the event of earthquake. A maximum response time limit, budget availability, multiple item types, and capacity restrictions are considered. In the model, the decision of the distribution centers to cover a disaster area and the amount of supplies to be stocked in each distribution center are simultaneously determined to maximize the total expected relief demand of the disaster areas covered by the existing distribution centers. The proposed model is applied to a real case with 33 disaster areas and 16 distribution centers in Indonesia. Several sensitivity analyses are conducted to estimate the fluctuation on the emergency stock pre-positioning planning by changing the maximum response time and budgets.

• KEPCO Journal on Electric Power and Energy
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• v.1 no.1
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• pp.79-84
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• 2015

Transformer is widely used element on power system and industrial area. Especially the transformers installed at power system are exposed to an environment of arbitrary changed. Thus the prediction of degradation and the analysis of response to impulse are important. To conduct those works, the electrical characteristics of system should be analyzed, effectively. But the analysis of electrical characteristic in electric machine level such as pole and pad-mounted transformer is almost no, thus commercial VNA (Vector Network Analyzer) is used to getting the response in wide frequency range. However, the output power of VNA is usually under 10mW, so verification for effectiveness of measuring electrically large component should be conducted, firstly. Next, after getting total S-parameter of transformer, predicting impulse response can be performed in time-domain with circuit simulator. In this paper, it is introduced that verification effectiveness of VNA using transfer function from SFRA (Sweep Frequency Response Analyzer), firstly. Next, total S-parameter, six by six matix form, was built using measured 2 port S-parameter from vector network analyzer. To get the response to impulse which is defined by IEC 60060-1, time-domain simulation is conducted to ADS (Advenced Design System) circuit simulator.

• Radiation Oncology Journal
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• v.36 no.2
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• pp.153-162
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• 2018

Purpose: We aimed to evaluate clinical outcomes including progression-free survival (PFS), overall survival (OS), partial response, and complete response in patients who underwent radiation therapy (RT) for mycosis fungoides (MF). Also, we sought to find prognostic factors for clinical outcomes. Materials and Methods: Total 19 patients confirmed with MF between 1999-2015 were retrospectively reviewed. Clinical and treatment characteristics, clinical outcomes, and and toxicities were analyzed. Results: Eleven patients were treated with total skin electron beam radiotherapy (TSEBT) and 8 patients with involved field radiation therapy (IFRT) with median dose of 30 Gy, respectively. The median time interval from diagnosis to RT was 2.6 months (range, 0.4 to 87.3 months). The overall response rate was 100%; 11 patients (57.9%) had a complete response and 8 patients (42.1%) a partial response. The presence of positive lymph node at the time of consultation of RT was associated with lower OS (p = 0.043). In multivariate analysis, PFS was significantly lower for patients with increased previous therapies experienced following RT (p = 0.019) and for patients showing PR during RT (p = 0.044). There were no reported grade 3 or more skin toxicities related with RT. Conclusion: Both IFRT and TSEBT are effective treatment for MF patients. Patients with short disease course before RT or complete response during RT are expected to have longer PFS. Positive lymph node status at the initiation of RT was associated woth poor OS, suggesting other treatment modalities such as low-dose RT for patients with low life-expectancy.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2005.03a
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• pp.487-494
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• 2005

In this study, a set of artificial earthquake time histories, which can be used for the earthquake-resistant design of seismically isolated highway bridges, was presented. In addition, adequateness of the generated ground accelerations was investigated. These were performed based on the seismic design standard for seismically isolated bridges. Total of 22 acceleration time histories were generated for each soil condition by the spectral method. The time histories were verified to meet the code provisions including (1) mean response spectrum at control frequencies, (2) EPGA (effective peak ground acceleration), and (3) correlation coefficient. Finally, the maximum response corresponding to four time histories and the mean response associated with seven time histories were computed using the generated acceleration time histories, which shows validity of the proposed artificial earthquake time histories.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.43 no.3
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• pp.68-76
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• 2020

In a series of recent launch tests, North Korea has been improving the firepower of its missiles that can target South Korea. North Korea's missiles and submarines are capable of threatening targets in South Korea and are likely faster and more covert than the systems previously seen in North Korea. The advanced threats require that ROK Navy should not only detect them earlier than ever but also response quicker than ever. In addition to increasing threats, the number of young man that can be enlisted for military service has been dramatically decreasing. To deal with these difficulty, ROK navy has been making various efforts to acquire a SMART warship having enhanced defense capability with fewer human resources. For quick response time with fewer operators, ROK Navy should improve the efficiency of systems and control tower mounted on the ship by promoting the Ship System Integration. Total Ship Computing Environment (TSCE) is a method of providing single computing environment for all ship systems. Though several years have passed since the first proposal of TSCE, limited information has been provided and domestic research on the TSCE is still in its infancy. In this paper, we apply TSCE with open architecture (OA) to solve the problems that ROK Navy is facing in order to meet the requirements for the SMART ship. We first review the level of Ship System Integration of both domestic and foreign ships. Then, based on analyses of integration demands for SMART warship, we apply real time OA to design architecture for TSCE from functional view and physical view. Simulation result shows that the proposed architecture has faster response time than the response time of the existing architecture and satisfies its design requirements.

• Journal of Biosystems Engineering
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• v.21 no.2
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• pp.155-166
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• 1996

A direct injection sprayer was designed using the concepts of injection mixing and total flow control, flowrate-based system compensating for the variation of forwarding speed. A metered rate, proportionally to the actual diluent flow rate, of a tracer chemical was injected directly into the diluent stream. The injection of chemical may improve the precision and safety of chemical application process. The control system was evaluated for the variables of the control interval, tolerances and sensitivities of flow regulation valve and injection pump. Performance of the system was assessed as that the response time of flow rate, response time of injection rate, absolute steady state error, and the coefficient of variance(C.V.) of concentration were 8.5 and -0.53 seconds, 0.067 lpm(0.8%) and 3.15%, respectively, at optimal parameters of control interval of 1.0 sec, fast sensitivity of flow regulation valve, medium sensitivity of injection pump and medium tolerance of flow rate. Performance of the system can be improved by increasing the sensitivity of flow regulating valve and employing a high resolution velocimeter, such as Doppler radar.

• Applied Chemistry for Engineering
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• v.28 no.4
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• pp.442-447
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• 2017

In this study, we extracted an antioxidant from natural products which are known to have a high antioxidant content and also optimized the extraction process by applying a response surface methodology (RSM). In addition, by measuring the total flavonoids and total polyphenols of the active ingredient extracted persimmon leaf and thistle, the functionality of the active ingredient was evaluated. Both ultrapure water and alcohol were used as extraction solvents and the ratio of ultrapure and alcohol, amount of sample, extraction time, extraction temperature were set as independence variables. Also, the yield, total polyphenols, and flavonoids was set as the response. Optimal extraction conditions were as follows; for persimmon leaf, the extraction time = 3.1 h, ratio of alcohol/ultrapure = 63.4 vol%, and temperature = $54.6^{\circ}C$ while for thistle the extraction time = 2.9 h, ratio of alcohol/ultrapure = 40.7 vol%, and temperature = $68.4^{\circ}C$. Also, the response were as follows; for persimmon leaf, the yield = 27.7%, total polyphenols = 33.2 mg GAE/g, and total flavonoids = 47.8 mg QE/mg dw, whereas for thistle the yield = 27.0%, total polyphenols = 17.9 mg GAE/g, and total flavonoids = 28.8 mg QE/mg dw at the optimal conditions. The overall satisfaction level was 71.7%.

• Korean Journal of Food Science and Technology
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• v.50 no.5
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• pp.474-479
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• 2018

In this study, ultrasound-assisted extraction conditions of total anthocyanins and total phenolic compounds from Campbell early grape (Vitis labruscana) were optimized via response surface methodology using a Box-Behnken design. Three independent variables, including solid-liquid ratio (1/30-1/50 g/mL), extraction time (2-10 min), and amplitude (20-100%), significantly affected total anthocyanin content. However, no significant effect of these variables was observed in the total phenolic compound content. The optimized extraction conditions were solid-liquid ratio of 1/48.13 g/mL, extraction time of 2 min, and amplitude of 20%. Under these conditions, the predicted values of total anthocyanins and total phenolic compounds were 94.96 and 1,661.16 mg/100 g dry weight (DW), respectively. The experimental values of total anthocyanins and total phenolic compounds were 88.25 and 1,554.37 mg/100 g DW, respectively, which is well matched with the predicted values within 7.5% difference.