• Title/Summary/Keyword: Top Management

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Prediction of hub genes of Alzheimer's disease using a protein interaction network and functional enrichment analysis

  • Wee, Jia Jin;Kumar, Suresh
    • Genomics & Informatics
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    • v.18 no.4
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    • pp.39.1-39.8
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    • 2020
  • Alzheimer's disease (AD) is a chronic, progressive brain disorder that slowly destroys affected individuals' memory and reasoning faculties, and consequently, their ability to perform the simplest tasks. This study investigated the hub genes of AD. Proteins interact with other proteins and non-protein molecules, and these interactions play an important role in understanding protein function. Computational methods are useful for understanding biological problems, in particular, network analyses of protein-protein interactions. Through a protein network analysis, we identified the following top 10 hub genes associated with AD: PTGER3, C3AR1, NPY, ADCY2, CXCL12, CCR5, MTNR1A, CNR2, GRM2, and CXCL8. Through gene enrichment, it was identified that most gene functions could be classified as integral to the plasma membrane, G-protein coupled receptor activity, and cell communication under gene ontology, as well as involvement in signal transduction pathways. Based on the convergent functional genomics ranking, the prioritized genes were NPY, CXCL12, CCR5, and CNR2.

A Study on the Prediction Analysis of Aviation Passenger Demand after Covid-19

  • Jin, Seong Hyun;Jeon, Seung Joon;Kim, Kyoung Eun
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.28 no.4
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    • pp.147-153
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    • 2020
  • This study analyzed the outlook for aviation demand for the recovery of the aviation industry, focusing on airlines facing difficulties in management due to the Covid-19 crisis. Although the timing of the recovery in aviation demand is uncertain at the moment, this study is based on prior research related to Covid-19 and forecasts by aviation specialists, and analyzed by SWOT technique to a group of aviation experts to derive and suggest implications for the prospects of aviation demand. Looking at the implications based on the analysis results, first, customer trust to prevent infection should be considered a top priority for recovering aviation demand. Second, promote reasonable air price policy. Finally, it seeks to try various research and analysis techniques to predict long-term aviation demand to overcome Covid-19.

A Study on the Corporate Management Strategy of OTT Service: Focusing on Coupang Play

  • Jae Hyun, Cho;Min Jung, Kang
    • International Journal of Internet, Broadcasting and Communication
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    • v.15 no.1
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    • pp.150-156
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    • 2023
  • In a recent study, the phenomena of attention being drawn to the media business, particularly over-the-top (OTT) services, was the focus. Particularly, after the Squid Game was broadcast in September 2021, the total number of Netflix users had topped 213.6 million since the company first entered the domestic market. Domestic companies have also introduced OTT services like 'Wave', 'Tving', and 'Watcha Play' to capitalize on this market trend. However, questions persist about how Korea's native OTT providers, both large and small, are being harmed by Netflix's strong financial position and massive content quantity. In order to offer realistic performance metrics, we analyze Coupang Play among domestic OTT service providers after reviewing the business model and management strategy of representative OTT service firms.

Explainable Software Employment Model Development of University Graduates using Boosting Machine Learning and SHAP (부스팅 기계 학습과 SHAP를 이용한 설명 가능한 소프트웨어 분야 대졸자 취업 모델 개발)

  • Kwon Joonhee;Kim Sungrim
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.19 no.3
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    • pp.177-192
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    • 2023
  • The employment rate of university graduates has been decreasing significantly recently. With the advent of the Fourth Industrial Revolution, the demand for software employment has increased. It is necessary to analyze the factors for software employment of university graduates. This paper proposes explainable software employment model of university graduates using machine learning and explainable AI. The Graduates Occupational Mobility Survey(GOMS) provided by the Korea Employment Information Service is used. The employment model uses boosting machine learning. Then, performance evaluation is performed with four algorithms of boosting model. Moreover, it explains the factors affecting the employment using SHAP. The results indicates that the top 3 factors are major, employment goal setting semester, and vocational education and training.

Skeleton Model-Based Unsafe Behaviors Detection at a Construction Site Scaffold

  • Nguyen, Truong Linh;Tran, Si Van-Tien;Bao, Quy Lan;Lee, Doyeob;Oh, Myoungho;Park, Chansik
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.361-369
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    • 2022
  • Unsafe actions and behaviors of workers cause most accidents at construction sites. Nowadays, occupational safety is a top priority at construction sites. However, this problem often requires money and effort from investors or construction owners. Therefore, decreasing the accidents rates of workers and saving monitoring costs for contractors is necessary at construction sites. This study proposes an unsafe behavior detection method based on a skeleton model to classify three common unsafe behaviors on the scaffold: climbing, jumping, and running. First, the OpenPose method is used to obtain the workers' key points. Second, all skeleton datasets are aggregated from the temporary size. Third, the key point dataset becomes the input of the action classification model. The method is effective, with an accuracy rate of 89.6% precision and 90.5% recall of unsafe actions correctly detected in the experiment.

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Globalizing the MEDIHEAL Brand: L&P Cosmetic's Collaboration with BTS

  • Kwon, Ick Hyun
    • Asia Marketing Journal
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    • v.21 no.2
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    • pp.51-71
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    • 2019
  • L&P Cosmetic, the leading company selling mask packs on the global market, produces MEDIHEAL, the number-one best-selling mask pack brand in Korea and the best-selling imported mask pack brand in China (2017). The company pioneered the premium market for mask packs through its launch of premium mask packs in 2009, and has subsequently achieved outstanding success in Korea and China. Three key factors have contributed to the success of L&P Cosmetic: product leadership with R&D capability, strategic marketing programs tailored for each market segment, and operational excellence focusing on strategic outsourcing and partnership management. Nonetheless, globalization beyond the Chinese market remains a major challenge for the potential of L&P Cosmetic. The company has embarked upon a collaboration with BTS, the world's top K-pop stars, as an optimally effective way to achieve its goals and a highly efficient strategy to manage the risks of globalization. The global branding collaboration project with BTS has succeeded in generating primary demand for mask packs on the global market, spreading brand awareness of MEDIHEAL, and establishing global channel networks. L&P Cosmetic will continue to grow worldwide on the basis of this outstanding performance.

A Study on the Cost Estimate System Development Method for Nuclear Power Plant Construction Projects

  • Lee, Sang Hyun
    • International conference on construction engineering and project management
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    • 2017.10a
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    • pp.133-137
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    • 2017
  • Nuclear power plants in Korea are usually built based on a duplicated model; so the project cost data of the preceding unit can be used as reference when estimating the project cost for the succeeding unit. However, since the contracting method is oriented towards the price, empirical factors such as making top-down estimations using the reverse calculation method based on the completion cost of the preceding unit is dominant. In order to develop a project cost database to resolve such problems, the detailed cost boundary of the project cost data must be categorized by project and by system. This study proposes a method to connect the code of account with the base quantities and the IAEA account, and proposes a database structure for the development of a project cost estimation system. The estimation system developed in the future is expected to utilize the proposed project cost data structure.

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Optimal Distribution Strategies by Considering Inbound and Outbound Transportation Costs (입고 출고 수송비용을 고려한 최적 배송전략)

  • Gitae Kim
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.46 no.4
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    • pp.116-123
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    • 2023
  • In supply chain, most partners except the top level suppliers have inbound and outbound logistics. For example, toll manufacturing companies get unprocessed materials from a requesting company and send the processed materials back to the company after toll processing. Accordingly, those companies have inbound and outbound transportation costs in their total logistics costs. For many cases, the company may make the schedule of distributions by considering only the due delivery dates. However, the inbound and outbound transportation costs could significantly affect the total logistics costs. Thus, this paper considers the inbound and outbound transportation costs to find the optimal distribution plans. In addition, we have considered the inventory holding costs as well with transportation costs. From the experimental results, we have provided the optimal strategies for the distributions of replenishment as well as deliveries.

HOLISTIC DECISION SUPPORT FOR BRIDGE REMEDIATION

  • Maria Rashidi;Brett Lemass
    • International conference on construction engineering and project management
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    • 2011.02a
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    • pp.52-57
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    • 2011
  • Bridges are essential and valuable elements in road and rail transportation networks. Bridge remediation is a top priority for asset managers, but identifying the nature of true defect deterioration and associated remediation treatments remains a complex task. Nowadays Decision Support Systems (DSS) are used extensively to assist in decision-making across a wide spectrum of unstructured decision environments. In this paper a requirements-driven framework is used to develop a risk based decision support model which has the ability to quantify the bridge condition and find the best remediation treatments using Multi Attribute Utility Theory (MAUT), with the aim of maintaining a bridge within acceptable limits of safety, serviceability and sustainability.

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A Study about The Impact of Music Recommender Systems on Online Digital Music Rankings (음원 추천시스템이 온라인 디지털 음원차트에 미치는 파급효과에 대한 연구)

  • Kim, HyunMo;Kim, MinYong;Park, JaeHong
    • Information Systems Review
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    • v.16 no.3
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    • pp.49-68
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    • 2014
  • These days, consumers have increasingly preferred to digital real-time streamlining and downloading to listen to music because this is convenient and affordable for the consumers. Accordingly, sales of music in compact disk formats have steadily declined. In this regards, online digital music has become a new communication channel to listen musics, where digital files can be delivered over various online networks to people's computing devices. The majority of online digital music distributors has Music Recommender Systems for sales of digital music on their websites. Music Recommender Systems are parts of information filtering systems that provide the ratings or preferences that users give to music. Korean online digital music distributors have Music Recommender Systems. But those online music distributors didn't provide any rules or clear procedures that recommend music. Therefore, we raise important questions as follows: "Is Music Recommender Systems Fair?", "What is the impact of Music Recommender Systems on online music rankings and sales?" While previous studies have focused on usefulness of Music Recommender Systems, this study investigates not only fairness of Current Music Recommender Systems but also Relationship between Music Recommender Systems and online Music Charts. This study examines these issues based on Bandwagon effect, ranking effect, Slot effect theories. For our empirical analysis, we selected the most famous five online digital music distributors in terms of market shares. We found that all recommended music is exposed to the top of 'daily music charts' in online digital music distributors' websites. We collected music ranking data and recommended music data from 'daily music chart' during a one month. The result shows that online music recommender systems are not fair, since they mainly recommend particular music that supported by a specific music production company. In addition, the recommended music are always exposed to the top of music ranking charts. We also find that recommended music usually appear at the top 20 ranking charts within one or two days. Also, the most music in the top 50 or 100 ranks are the recommended music. Moreover, recommended music usually remain the ranking charts more than one month while non-recommended music often disappear at the ranking charts within two week. Our study provides an important implication to online music industry. Because music recommender systems and music ranking charts are closely related, music distributors may improperly use their recommender systems to boost the sales of music that related to their own companies. Therefore, online digital music distributor must clearly announce the rules and procedures about music recommender systems for the better music industry.