• Title/Summary/Keyword: Tooth generation

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Development of Organic Paste Porcelain for Fixed Prostheses (유기조성물을 이용한 페이스트형 일반도재 시스템)

  • Han, Jung-Suk;Lee, Myung-Hyun;Kim, Dae-Hyun;Chung, Hun-Young
    • Journal of Dental Rehabilitation and Applied Science
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    • v.20 no.2
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    • pp.109-120
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    • 2004
  • INTRODUCTION: The build-up method has been used for application of porcelain powder on the metal framework to make final tooth shape conventionally. This method takes time and need skill to mimic final shade and shape of porcelain fused to metal crown. The purpose of this study was to develop standard shape and shade laminating porcelain forms to reduce build-up time. METHODS: To make tooth form porcelain paste, several liquid organic compounds were added to conventional feldspathic porcelain. The amount of additives and rheologic property were tested to find out best composition. Comparison of mixing methods to reduced porosity, proper heating schedule, and measurement of shrinkage amount and residual organic materials were performed to set-up standard procedures. Finally, biaxial flexural strength and color of preformed laminated paste porcelain were compared with those of porcelain which fabricated by the conventional build-up method. RESULTS: There was no significant difference in physical properties and color stability between two fabrication methods after various testing methods. Conclusion: This new build-up method can be applied to fabricate the PFM crown and bridge without any loss of strength and optical properties.

Generation of antibodies against N-terminus fragment of AgI/II protein from Streptococcus mutans GS-5 (연쇄상구균(Streptococcus mutans GS-5)의 항원단백질 AgI/II의 N-terminus절편에 대한 항체형성)

  • Han, Ji-Hye;Baik, Byeong-Ju;Yang, Yeon-Mi;Park, Jeong-Yeol;Kim, Jae-Gon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.33 no.3
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    • pp.401-410
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    • 2006
  • Dental caries results from localized demineralization of tooth enamel by acids of bacterial origin produced from the fermentation of dietary sugars. A group of related oral bacteria, collectively known as mutans streptococci, are implicated as the primary etiological agents of human caries. Within this group, Streptococcus mutans has been known as a causative agent for dental caries. As well as acid production yielding the demineralization of tooth enamel, adherence and colonization of S. mutans to the teeth are also important for their virulence Cell-surface fibrillar proteins, which mediate adherence to the salivary pellicle are virulence components of mutans streptococci, and primary candidates for a human caries vaccine. Here we report that the AgI/II gene from S. mutans GS-5 were cloned by PCR amplification of the bacterial chromosomal DNA and the integrity of cloned genes were confirmed by nucleotide sequencing. Sequence analyses showed the sequence alignment of 280 nucleotides between the cloned AgI/II and the reported sequence of S. mutans GS-5 showed the perfect match The cloned genes which signal nucleotide was truncated, were transferred into bacterial expression vector and the recombinant proteins were purified as His-tag fusion proteins In order to generate polyclonal antibodies against the recombinant proteins, AgI/II mr, some $100{\mu}g$ of the proteins was injected into mice three times. It can be used for an effective vaccine production to prevent dental caries caused by pathogenic S. mutans.

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Successful Conservative Surgical Treatment of Ameloblastic Fibroma in the Posterior Maxilla : A Case Report (상악 구치부에 발생한 법랑모세포섬유종의 성공적인 보존적 수술 : 증례 보고)

  • Lee, Youngeun;Ahn, Hyojung;Lee, Sooeon;Kim, Euncheol;Choi, Sungchul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.40 no.4
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    • pp.321-327
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    • 2013
  • Ameloblastic fibroma (AF) is a rare odontogenic ectomesenchymal tumor that is frequently seen in the first two decades of life, and occurs in the mandible. The most proper management of AF has been a recent topic of debate because of its recurrence and malignant transformation. This report describes AF in a 4-year-old male, which was a unilocular radiolucency on the maxillary right primary molar area with a scalloped border and corticated margin. The tumor was treated conservatively with enucleation and curettage, and the decision was made to preserve the right primary second molar. A biopsy confirmed it as AF. During the 43 months of follow-up, the patient had no evidence of recurrence or malignant transformation. Moreover, the radiographic examination revealed the generation of tooth germ to be a permanent second premolar. This report shows a case of AF in the posterior maxilla of a 4-year-old boy and discusses the conservative therapeutic approach to this tumor. Therefore, the age of the patients should be an important consideration when choosing conservative or radical surgery in a young AF patient.

Blood Vessel Regeneration using Human Umbilical Cord-derived Endothelial Progenitor Cells in Cyclophosphamide-treated Immune-deficient Mice

  • Kwon, Soon-Keun;Ko, Yu-Jin;Cho, Tae-Jun;Park, Eu-Gene;Kang, Byung-Chul;Lee, Gene;Cho, Jae-Jin
    • International Journal of Oral Biology
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    • v.36 no.3
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    • pp.117-122
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    • 2011
  • Endothelial cells are a vital constituent of most mammalian organs and are required to maintain the integrity of these tissues. These cells also play a major role in angiogenesis, inflammatory reactions, and in the regulation of thrombosis. Angiogenesis facilitates pulp formation and produces the vessels which are essential for the maintenance of tooth homeostasis. These vessels can also be used in bone and tissue regeneration, and in surgical procedures to place implants or to remove cancerous tissue. Furthermore, endothelial cell regeneration is the most critical component of the tooth generation process. The aim of the present study was to stimulate endothelial regeneration at a site of acute cyclophosphamide (CP)-induced endothelial injury by treatment with human umbilical cord-derived endothelial/mesenchymal stem cells (hEPCs). We randomly assigned 16 to 20-week-old female NOD/SCID mice into three separate groups, a hEPC ($1{\times}10^5$ cells) transplanted, 300mg/kg CP treated and saline (control) group. The mice were sacrificed on days 5 and 10 and blood was collected via the abdominal aorta for analysis. The alanine transaminase (ALT), aspartate aminotransferase (AST), serum alkaline phosphatase (s-ALP), and albumin (ALB) levels were then evaluated. Tissue sections from the livers and kidneys were stained with hematoxylin and eosin (HE) for microscopic analysis and were subjected to immunohistochemistry to evaluate any changes in the endothelial layer. CP treatment caused a weight reduction after one day. The kidney/body weight ratio increased in the hEPC treated animals compared with the CP only group at 10 days. Moreover, hEPC treatment resulted in reduced s-ALP, AST, ALT levels compared with the CP only group at 10 days. The CP only animals further showed endothelial injuries at five days which were recovered by hEPC treatment at 10 days. The number of CD31-positive cells was increased by hEPC treatment at both 5 and 10 days. In conclusion, the CP-induced disruption of endothelial cells is recovered by hEPC treatment, indicating that hEPC transplantation has potential benefits in the treatment of endothelial damage.

Effect of different denture cleansers on surface roughness and microhardness of artificial denture teeth

  • Yuzugullu, Bulem;Acar, Ozlem;Cetinsahin, Cem;Celik, Cigdem
    • The Journal of Advanced Prosthodontics
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    • v.8 no.5
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    • pp.333-338
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    • 2016
  • PURPOSE. The aim of this study was to compare the effects of different denture cleansers on the surface roughness and microhardness of various types of posterior denture teeth. MATERIALS AND METHODS. 168 artificial tooth specimens were divided into the following four subgroups (n=42): SR Orthotyp PE (polymethylmethacrylate); SR Orthosit PE (Isosit); SR Postaris DCL (double cross-linked); and SR Phonares II (nanohybrid composite). The specimens were further divided according to the type of the denture cleanser (Corega Tabs (sodium perborate), sodium hypochlorite (NaOCl), and distilled water (control) (n=14)) and immersed in the cleanser to simulate a 180-day immersion period, after which the surface roughness and microhardness were tested. The data were analyzed using the Kruskal-Wallis test, Conover's nonparametric multiple comparison test, and Spearman's rank correlation analysis (P<.05). RESULTS. A comparison among the denture cleanser groups showed that NaOCl caused significantly higher roughness values on SR Orthotyp PE specimens when compared with the other artificial teeth (P<.001). Furthermore, Corega Tabs resulted in higher microhardness values in SR Orthotyp PE specimens than distilled water and NaOCl (P<.005). The microhardness values decreased significantly from distilled water, NaOCl, to Corega Tabs for SR Orthosit PE specimens (P<.001). SR Postaris DLC specimens showed increased microhardness when immersed in distilled water or NaOCl when compared with immersion in Corega Tabs (P<.003). No correlation was found between surface roughness and microhardness (r=0.104, P=.178). CONCLUSION. NaOCl and Corega Tabs affected the surface roughness and microhardness of all artificial denture teeth except for the new generation nanohybrid composite teeth.

In vivo assessment of accuracy of Propex II, Root ZX II, and radiographic measurements for location of the major foramen

  • Tampelini, Fernanda Garcia;Coelho, Marcelo Santos;de Azevedo Rios, Marcos;Fontana, Carlos Eduardo;Rocha, Daniel Guimaraes Pedro;Pinheiro, Sergio Luiz;da Silveira Bueno, Carlos Eduardo
    • Restorative Dentistry and Endodontics
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    • v.42 no.3
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    • pp.200-205
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    • 2017
  • Objectives: The aim of this in vivo study was to assess the accuracy of 2 third-generation electronic apex locators (EALs), Propex II (Dentsply Maillefer) and Root ZX II (J. Morita), and radiographic technique for locating the major foramen (MF). Materials and Methods: Thirty-two premolars with single canals that required extraction were included. Following anesthesia, access, and initial canal preparation with size 10 and 15 K-flex files and SX and S1 rotary ProTaper files, the canals were irrigated with 2.5% sodium hypochlorite. The length of the root canal was verified 3 times for each tooth using the 2 apex locators and once using the radiographic technique. Teeth were extracted and the actual WL was determined using size 15 K-files under a ${\times}25$ magnification. The Biostat 4.0 program (AnalystSoft Inc.) was used for comparing the direct measurements with those obtained using radiographic technique and the apex locators. Pearson's correlation analysis and analysis of variance (ANOVA) were used for statistical analyses. Results: The measurements obtained using the visual method exhibited the strongest correlation with Root ZX II (r = 0.94), followed by Propex II (r = 0.90) and Ingle's technique (r = 0.81; p < 0.001). Descriptive statistics using ANOVA (Tukey's post hoc test) revealed significant differences between the radiographic measurements and both EALs measurements (p < 0.05). Conclusions: Both EALs presented similar accuracy that was higher than that of the radiographic measurements obtained with Ingle's technique. Our results suggest that the use of these EALs for MF location is more accurate than the use of radiographic measurements.

A CAD/CAM-based strategy for concurrent endodontic and restorative treatment

  • Escobar, Patricia Maria;Kishen, Anil;Lopes, Fabiane Carneiro;Borges, Caroline Cristina;Kegler, Eugenio Gabriel;Sousa-Neto, Manoel Damiao
    • Restorative Dentistry and Endodontics
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    • v.44 no.3
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    • pp.27.1-27.12
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    • 2019
  • This case report describes a technique in which endodontic treatment and permanent indirect restoration were completed in the same clinical appointment with the aid of a computer-aided design/computer-aided manufacturing (CAD/CAM) system. Two patients were diagnosed with irreversible pulpitis of the mandibular first molar. After access preparation, root canals were located, irrigation was performed until bleeding ceased, and the coronal tooth structure was prepared for indirect restoration. Then, utilizing an interim 3-mm build-up of the endodontic access cavity, a hemi-arch digital scan was performed with an intraoral scanner. Subsequent to digital scanning, restoration design was performed simultaneously with the endodontic procedure. The root canals were shaped using the Race system under irrigation with 2.5% sodium hypochlorite followed by root canal filling. The pulp chamber was subsequently filled with a 3-mm-thick composite resin restoration mimicking the interim build-up previously utilized to facilitate block milling in the CAD/CAM system. Clinical try-in of the permanent onlay restoration was followed by acid etching, application of a 5th generation adhesive, and cementation of the indirect restoration. Once the restoration was cemented, rubber dam isolation was removed, followed by occlusal adjustment and polishing. After 2 years of follow-up, the restorations were esthetically and functionally satisfactory, without complications.

Real-time Tooth Region Detection in Intraoral Scanner Images with Deep Learning (딥러닝을 이용한 구강 스캐너 이미지 내 치아 영역 실시간 검출)

  • Na-Yun, Park;Ji-Hoon Kim;Tae-Min Kim;Kyeong-Jin Song;Yu-Jin Byun;Min-Ju Kang․;Kyungkoo Jun;Jae-Gon Kim
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.46 no.3
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    • pp.1-6
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    • 2023
  • In the realm of dental prosthesis fabrication, obtaining accurate impressions has historically been a challenging and inefficient process, often hindered by hygiene concerns and patient discomfort. Addressing these limitations, Company D recently introduced a cutting-edge solution by harnessing the potential of intraoral scan images to create 3D dental models. However, the complexity of these scan images, encompassing not only teeth and gums but also the palate, tongue, and other structures, posed a new set of challenges. In response, we propose a sophisticated real-time image segmentation algorithm that selectively extracts pertinent data, specifically focusing on teeth and gums, from oral scan images obtained through Company D's oral scanner for 3D model generation. A key challenge we tackled was the detection of the intricate molar regions, common in dental imaging, which we effectively addressed through intelligent data augmentation for enhanced training. By placing significant emphasis on both accuracy and speed, critical factors for real-time intraoral scanning, our proposed algorithm demonstrated exceptional performance, boasting an impressive accuracy rate of 0.91 and an unrivaled FPS of 92.4. Compared to existing algorithms, our solution exhibited superior outcomes when integrated into Company D's oral scanner. This algorithm is scheduled for deployment and commercialization within Company D's intraoral scanner.

PHYSICAL PROPERTIES OF VAR10US BRANDS OF ELASTOMERIC CHAINS (수종의 합성 고무탄성재의 성질에 관한 연구)

  • Kim, Kyung-Ho;Hwang, Chung-Ju;Sung, Sang-Jin
    • The korean journal of orthodontics
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    • v.27 no.6 s.65
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    • pp.943-954
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    • 1997
  • Forces needed for orthodontic tooth movement are obtained from various appliances such as orthodontic wires or elastic rubber. Orthodontic elastic rubber is widely used clinically, but permanent deformation and force decay may occur from the environmental changes, time of clinical use and the extent of the stretch, making the Prediction of force being applied difficult. The Present study examined and compared the changes in residual force between three brands of elastomeric chains (Ormco Generation II Power Chains ; brand A, RMO : Energy-Chain ; brand B, Unitek : AlastiK ; brand C) under various environmental conditions, amount of initial force, types of elastomer and the rate of extension. The characteristic physical properies of the elastomeric chains were as follows. 1. In all three brands, the residual force ratio was largest when the chains were stored in air, with no difference between water and saliva. 2. In all three brands, after 24 hours, there was no statistical difference in residual force ratio according to the initial force level. 3. In Brand A and B, the presence of filament had no correlation with the residual force ratio. In Brand C force decay was more severe when the chain contained filament. 4. In each brand, rate of extension had no effect on residual force ratio. 5. Brand B showed relatively higher residual force ratio compared to other brands.

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Development of Round Trip Occurrence Simulator Considering Tooth Wear of Drill Bit (시추비트의 마모도를 고려한 라운드 트립 발생 예측 시뮬레이터 개발)

  • Lee, Seung Soo;Kim, Kwang Yeom;Shin, Hyu-Soung
    • Tunnel and Underground Space
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    • v.23 no.6
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    • pp.480-492
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    • 2013
  • After the introduction of geothermal power generation technology based on engineering reservoir creation that can be applied on non-volcanic region, industrial need for studies on the efficient and economic execution of costly deep-depth drilling work becomes manifest increasingly. However, since it is very difficult to predict duration and cost of boring work with acceptable reliability because of many uncertain events during the execution, efficient and organized work management for drilling is not easily achievable. Especially, the round trip that discretely occurs because of the abrasion of bit takes more time as the depth goes deeper and it has a great impact on the work performance. Therefore, a technology that can simulate the occurrence timing and depth of round trip in advance and therefore optimize them is essentially required. This study divided the abrasion state of bit into eight steps for simulation cases and developed a forecast algorithm, i.e., TOSA which can analyze the depth and timing of round trip occurrence. A methodology that can divide a unit section for simulation has been suggested; while the Bourgoyne and Young model has been used for the forecast of drilling rates and bit abrasion extent by section. Lastly, the designed algorithm has been systemized for the convenience of the user.