• 청정기술
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• 제22권1호
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• pp.45-52
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• 2016

This study reports on the modeling and simulation of heat transfer in packaging boxes used for vaccine shipping. Both water and n-tetradecane are used as primary insulation materials inside a multi-slab system. The one-dimensional model, which is a spherical model using a radius equivalent to the rectangular geometry of container, is applied in this study. N-tetradecane with low thermal diffusivity and proper phase transition temperature exhibits higher heat transfer resistance during both heating and cooling processes compared to water. Thus, n-tetradecane is a better candidate as an insulating material for packaging containers for vaccine shipping. Furthermore, the developed method can also become a rapid and economic tool for screening appropriate phase change materials used as insulation materials with suitable properties in logistics applications.

• Journal of Microbiology and Biotechnology
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• 제9권5호
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• pp.655-660
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• 1999

Sphingomyelinase (SMase EC:3.l.4.l2) has been suggested to play important roles in the cell cycle, differentiation, apoptosis, inflammation, and the regulation of eukaryotic stress responses. SMase inhibitors may be a powerful tool to elucidate and regulate these cellular responses in which SMase involves. We first isolated an SMase inhibitor, named sphinin, from a strain of soil actinomycetes, F50970. Sphinin inhibited Mg/sup 2+/ -dependent neutral SMase from chicken embryo at 1.2 ㎍/㎖ of IC/sub 50/ Sphinin also inhibited acidic SMase, but it had no inhibitory activity on PI-PLC and PC-PLC, suggesting that sphinin is a specific inhibitor of SMase. The strain F50970 was identified as a Streptomyces sp. by its spiral spore chain, LL-diaminopimelic acid, menaquinone patterns of MK-9 (H'6) and MK-9 (H'8), FA-2c type of fatty acid pattern, and other morphological, physiological, and cultural characteristics.

• 품질경영학회지
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• 제29권4호
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• pp.116-132
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• 2001

The world wide web has been growing rapidly. Due to the development, many companies are using the e-commerce through the web as an another tool for the their deal with customers. The internet is utilized as the new distribution business and channel for the most companies. This innovative changes made many people to purchase products through the web. However, there are a lot of problems during the process of supply chain channels. This research is about the impact of service quality on the customer satisfaction in the business-to-consumer(B2C) e-commerce. It was performed by utilizing the methodology for measuring the degree of service quality which has been adopted in the service quality research area. The quality of service is made up of six dimensions(factors): reliability, responsiveness, assurance, empathy, tangible, and convenience. Therefore, we studied the influence of these six factors upon the customer satisfaction, and the results will be summarized.

• 한국공작기계학회논문집
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• 제13권2호
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• pp.81-87
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• 2004

This paper deals with a new approach to tolerance optimization problems. Optimal tolerance allotment problems can be formulated as stochastic optimization problems. Most schemes to solve the stochastic optimization problems have been found to exhibit difficulties in multivariate integration of the probability density function. As a typical example of stochastic optimization the optimal tolerance allotment problem has the same difficulties. In this stochastic model, manufacturing system is represented by Gauss-Markov stochastic process and the manufacturing unit availability is characterized for realistic optimization modeling. The new algorithm performed robustly for a large deviation approximation. A significant reduction in computation time was observed compared to the results obtained in previous studies.

• 한국컴퓨터정보학회논문지
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• 제22권7호
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• pp.93-100
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• 2017

In this paper, we propose a methodology of using time-lag, make it serve the sound field, in order to smoothen the music production and reduce conflicts. The importance of music production in today's music industry chain is becoming more and more apparent. In the process of music production, the creators pay more attention to the design and adjustment of virtual sound field, especially the late mixing and production. In the process, as a commonly used tool for the adjustment of sound field, "time-lapse" plays a decisive role.

• 대한안전경영과학회지
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• 제6권3호
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• pp.327-337
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• 2004

The soaring increase in the number of Internet users combined with the constant computerization of business process has created new opportunities for computer criminals and terrorist. Fortunately, the computer security field is also progressing at a brisk rate. In particular, the field of computer forensics brings new ways of preserving and analyzing evidence related to computer crime. Computer forensics is a new emerging professions of the 21st century. It is the collection, preservation, analysis, and presentation of computer related evidence. For this reason, the various technology of computer forensics is regarded as a powerful tool for suppressing computer crime. Our aims is to introduce the overview of computer forensics technology. We also present the survey results of the state of the art of computer forensics in the domestics and of foreign country.

• 대한안전경영과학회지
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• 제5권2호
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• pp.215-223
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• 2003

GE, as well as Motorola, TI, HP, ABB, and other companies, which have several suppliers from all of the world, adopted an innovation program called 6 Sigma, in order to make fundamental changes in the way they operated to fulfill customers' expectations and to evaluate and control their suppliers. Recently, as the 6 Sigma is being recognized as elementary and strategic means to improve the effectiveness of SCM(Supply Chain Management), there may be few business who does not operate 6 Sigma innovation program. Under such a circumstance, this study is aimed at expediting 6 Sigma pervasion by considering supplier evaluating scheme. It is recognized that this evaluating mechanism can be used as a great tool for the everlasting run of 6 Sigma in Korea.

• Mycobiology
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• 제30권1호
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• pp.5-12
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• 2002

A total of 100 samples of chicken-viscera were collected from different poultry-slaughtering houses in Austria;(20 samples of each of gizzard, heart, intestine, liver and spleen). Intestine and gizzard were heavy contaminated with moulds than other examined visceral organs($4.4{\times}10^5$ and $2.6{\times}10^4$ colonies/1g of the samples, respectively). Fungal contamination was not detected in all samples of heart and spleen. Eighty-five mould isolates were collected from the examined samples, the majority of isolates belonging to Aspergillus glaucus group(20.0%) and Trichoderma(14.1%). These isolates comprised 15 species belonging to 9 genera. Members of Aspergillus glaucus(telomorph: Eurotium) group and Trichoderma were further confirmed their identification using random amplified polymorphic DNA-polymerase chain reaction(RAPD-PCR) technique.

• 대한안전경영과학회지
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• 제10권1호
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• pp.139-144
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• 2008

Recently, a multi-facility, multi-product and multi-period industrial production-distribution planning problem has been widely investigated in Supply Chain Management (SCM). One of the key issues in the current SCM research area involves reducing both production and distribution costs. We have developed an optimization model to tackle the above problems under the restricted conditions such as transportation time and a zero inventory. Computational experiments using commercial tool Ms-Excel Solver show that the real size problems we encountered can be solved in reasonable time. The model can be used to decide an appropriate production-distribution planning problem in SCM research area.

• Archives of Pharmacal Research
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• 제28권2호
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• pp.129-141
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• 2005

(-)-Fumagillol (1), a hydrolysis product of fumagillin, has been synthesized by several group from commercially available 1,2:5,6-di-O-isopropylidene-${\alpha}$-D-allofuranose in a highly stereoselective manner. Chiral centers on C5 and C6 came from D-allofuranose and the asymmetric center on C4 was accomplished by 1,3-chirality transfer using the Claisen rearrangement on a chiral allyl alcohol. Chirality, which is necessary on an epoxide consisting of the spiro-ring system, was diastereoselectively constructed by the well-known reaction, intramolecular ester enolate alkylation (IEEA), which showed that this reaction can be applied to the alpha-alkoxy ester system. The epoxide on the side chain was regioselectively introduced by the difference between the number of substituents on the vinyl groups. This accomplishment proved that IEEA can be a useful tool for the synthesis of complex molecules.