• Advances in concrete construction
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• v.1 no.3
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• pp.201-213
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• 2013

While recognizing the problem of reinforcement corrosion and premature structural deterioration of reinforced concrete (RC) structures as a combined effect of mechanical and environmental actions (carbonation, ingress of chlorides), emphasis is given on the effect of the latter, as most severe and unpredictable action. In this study, a simulation tool, based on proven predictive models utilizing principles of chemical and material engineering, for the estimation of concrete service life is applied on an existing reinforced concrete bridge (${\O}$resund Link) located in a chloride environment. After a brief introduction to the structure of the models used, emphasis is given on the physicochemical processes in concrete leading to chloride induced corrosion of the embedded reinforcement. By taking under consideration the concrete, structural and environmental properties of the bridge investigated, an accurate prediction of its service life is taking place. It was observed that the proposed, and already used, relationship of service lifetime- cover is almost identical with a mean line between the lines derived from the minimum and maximum critical values considered for corrosion initiation. Thus, an excellent agreement with the project specifications is observed despite the different ways used to approach the problem. Furthermore, different scenarios of concrete cover failure, in the case when a coating is utilized, and extreme deicing salts attack are also investigated.

• Architectural research
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• v.23 no.2
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• pp.19-28
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• 2021

Reduction in competence makes older adults with dementia more sensitive to the influence of the physical environment. The aim of the longitudinal study was to examine whether residents with dementia in long-term facilities with variability in physical environmental characteristics in Vancouver (N= 11), Canada and Stockholm (N=13), Sweden had a difference in their quality of life (QoL). QoL was assessed using Dementia Care Mapping tool three times over one year for the reliability of data. The results of the study demonstrated that the residents with dementia living in a homelike and positive stimulating setting showed less withdrawn behaviors and a higher level of well-being compared to those in a large-scale institutional setting. This study also found that the residents living in a large-scale institutional environment spent more monotonous times than the other groups, which may be to provision of fewer structured activity programs or less social interaction with neighbors or staff members. Residents living in a large-scale institutional setting in Canada showed so far as five times more agitated/ distressed behaviors and twice more withdrawal compared to the ones living in a small-scale homelike setting in Sweden. The study supports that the large-scale institutional environment was considerably associated with levels of lower quality of life among the residents with dementia.

• International Journal of Advanced Culture Technology
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• v.10 no.4
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• pp.181-189
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• 2022

The purpose of this study is to verify study models and examine a causal relationship among authenticity, job satisfaction, organizational commitment, quality of life and job achievement for amateur business team player. In order to achieve the purpose, this study conducted structural equation model analysis for study models consisting of extraneous variables after examining the authenticity(organization, leader) that amateur business players perceive and endogenous variables including job satisfaction, organizational commitment, quality of life, and job performance. The object of questionnaires in this study selected sports business team players nationwide as a population and 348 players were chosen as final effective samples by applying a convenient sampling method for offline and online questionnaires. The research tool for this study is a questionnaire. The two dimensions of authenticity were used by developing a scale. For all endogenous variables, the scales used in previous studies were modified and used according to the purpose of the study. This study analyzed the collected data, applying SPSS Win ver. 23.0 and AMOS 20.0 programs in order to analyze the characteristics of the study objects, describe questionnaires, and verify selected study hypothesis, individual hypothesis was verified after identifying the reliability and validity of measurement model, and the fitness verification of study models. In the results, all of the 8 hypothesis were adopted and the reciprocal relationship among each factors in the study model were observed.

• Molecules and Cells
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• v.45 no.11
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• pp.820-832
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• 2022

As a potential candidate to generate an everlasting cell source to treat various diseases, embryonic stem cells are regarded as a promising therapeutic tool in the regenerative medicine field. Cohesin, a multi-functional complex that controls various cellular activities, plays roles not only in organizing chromosome dynamics but also in controlling transcriptional activities related to self-renewal and differentiation of stem cells. Here, we report a novel role of the α-kleisin subunits of cohesin (RAD21 and REC8) in the maintenance of the balance between these two stem-cell processes. By knocking down REC8, RAD21, or the non-kleisin cohesin subunit SMC3 in mouse embryonic stem cells, we show that reduction in cohesin level impairs their self-renewal. Interestingly, the transcriptomic analysis revealed that knocking down each cohesin subunit enables the differentiation of embryonic stem cells into specific lineages. Specifically, embryonic stem cells in which cohesin subunit RAD21 were knocked down differentiated into cells expressing neural alongside germline lineage markers. Thus, we conclude that cohesin appears to control the fate determination of embryonic stem cells.

• International Journal of Advanced Culture Technology
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• v.12 no.2
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• pp.427-437
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• 2024

The purpose of this study is to determine the impact of Chinese international students' academic resilience on acculturation stress and college life adjustment. In order to achieve this research objective, the research subjects were Chinese students participating in sports in Korea. The sampling method was convenience sampling, and a total of 300 people, 150 men and 150 women, were selected as research subjects through sharing the questionnaire link online and email. The research tool used in this study was a questionnaire. Based on the questionnaire that had secured reliability and validity in previous research, it was modified and supplemented to suit this study. The statistical analysis used for data analysis was frequency analysis, exploratory factor analysis, reliability analysis, and multiple regression analysis using SPSS Windows 22.0 Version. The conclusions obtained in this study through data analysis according to these methods and procedures are as follows. First, the academic elasticity of Chinese students participating in sports has partially influenced by cultural adaptation stress. Second, the academic elasticity of Chinese students participating in sports has partially influenced by university life. Third, the acculturation stress of Chinese students participating in sports was found to partially affect their adaptation to university life.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.3
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• pp.309-315
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• 2018

Objective: This study aimed to test the expression patterns of ERBB receptor feedback inhibitor 1 (ERRFI1) before and after exercise and the association of non-synonymous single-nucleotide polymorphisms (nsSNPs) of horse ERRFI1 with racing traits in Thoroughbreds. Methods: We performed bioinformatics and gene expression analyses for horse ERRFI1. Transcription factor (TF) binding sites in the 5'-regulatory region of this gene were identified through a tool for prediction of TF-binding site (PROMO). A general linear model was used to detect the association between the nsSNP (LOC42830758 A to G) and race performance. Results: Quantitative polymerase chain reaction analysis showed that expression level of ERRFI1 after exercise was 1.6 times higher than that before exercise. Ten transcription factors were predicted from the ERRFI1 regulatory region. A novel nsSNP (LOC42830758 A to G) was found in ERRFI1, which was associated with three racing traits including average prize money, average racing index, and 3-year-old starts percentile ranking. Conclusion: Our analysis will be helpful as a basis for studying genes and SNPs that affect race performance in racehorses.

• Journal of Korean society of Dental Hygiene
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• v.12 no.5
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• pp.1039-1048
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• 2012

Objectives : The objective of this paper is to clarify the factors of the geriatric oral health influencing oral health-related quality of life by using the contracted OHIP-14 tool. Methods : This research conducted individual interview for 177 seniors using senior citizen center by using structured questionnaires. SAS(Ver.9.2) Program was used for the collected data to perform frequency analysis, reliability and scale analysis, t-test, ANOVA, correlation analysis and multiple regression analysis. Results : The oral health-related quality of life level related to oral health according to the demographical characteristics showed that it was better in case that they are younger, married, more educated and have more living expenses. Except for age, oral health-related quality of life was connected to scholastic achievement, living expenses, subjective health condition and subjective oral health condition. The factors influencing the oral health condition were subjective health condition, marriage, scholastic achievement, living expenses, age and sex. As the subjective health condition is better, in case of cohabitation of only a couple and as the age or scholastic achievement is higher and the living expenses are more, the oral health condition was better. The factors influencing oral health-related quality of life were subjective oral health condition, marriage, sex, subjective health condition, scholastic achievement and living expenses. As the subjective oral health condition and health condition were better and in case of sole living and cohabitation of only a couple, male's oral health-related quality of life was higher. Conclusions : It is considered that because the geriatric oral health condition becomes an important factor to oral health-related quality of life, the development of the geriatric oral health business and the geriatric heal education program to maintain and improve oral health is required and the activation of the oral health insurance policy for preventive dental service is necessary.

• Journal of Korean Academy of Nursing
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• v.45 no.5
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• pp.661-670
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• 2015

Purpose: The purpose of this study was to examine the mediation of psychological distress in the relationship between disturbance in ADL from chemotherapy induced peripheral neuropathy and quality of life in order to provide a basis for planning nursing interventions to improve the quality of life in cancer patients. Methods: A purposive sample of 130 patients treated with chemotherapy were recruited in the cross-sectional survey design. Data were collected using self-report questionnaires. The instruments were the Chemotherapy Induced Peripheral Neuropathy Assessment Tool (CIPNAT), Hospital Anxiety Depression Scale (HADS), and Functional Assessment of Cancer Therapy-General (FACT-G). Results: The mean score for disturbance in ADL from chemotherapy induced peripheral neuropathy was 3.30. Overall quality of life was 2.48. The mean score was 1.04 for psychological distress. The prevalence was 35.4% for anxiety and 47.7% for depression. There were significant correlations among the three variables, disturbance in ADL from chemotherapy induced peripheral neuropathy, psychosocial distress, and quality of life. Psychosocial distress had a complete mediating effect (${\beta}$= -.74, p <.001) in the relationship between disturbance in ADL from chemotherapy induced peripheral neuropathy and quality of life (Sobel test: Z= -6.11, p <.001). Conclusion: Based on the findings of this study, nursing intervention programs focusing on disturbance of ADL management, and decrease of psychological distress are highly recommended to improve quality of life in cancer patients.

• The Korean Journal of Archival Studies
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• no.67
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• pp.237-266
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• 2021

In archival science studies, personal archives is a relatively unexplored field. In particular, it is difficult to find a way for ordinary individuals to organize an archive for themselves. This study suggests how individuals organize archives for themselves and suggests life memory composition as a way to utilize them. For the structure and metadata design of life-time narratives archives, this study refers to Narratologie studies and memory studies of psychology, which are combined with the concept of hierarchy and collectivity of archives. In addition, the plot concept of the narrative was proposed to form a life narrative, which was used as a tool to construct one's own life narrative. Research into the composition and utilization of these life-time narrative archives may be helpful when individuals want to create archives for themselves in the future.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.2
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• pp.173-181
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• 2021

Purpose : The purpose of this study was to identify the clinical effect, assessment, method, and recent trend of the programs by systematically reviewed community-based programs for the elderly's quality of life conducted in the last ten years, and to present comprehensive basic data for occupational therapists who want to apply community-based programs improving quality of life. Methods : This study identified 811 studies from among those registered in the RISS, KISS, DBpia, NDSL, and KCI databases from January to September 2020, using "elderly," "community elderly," "65 aged," "quality of life," "occupational therapy," "occupational therapy program," "intervention," and "intervention program" as keywords. From these results, 11 documents were selected. Results : It was found that studies of occupational therapy programs for the quality of life of the elderly have been continuously conducted since 2010, and most of them were non-random control studies. The quality of life evaluation tool used most frequently was SF-36, and WHOQOL-BREF and SF-8 were also used. The selected programs were classified as were exercise programs and complex programs. For most of the exercise programs, interventions were carried out for 12 weeks, three times a week for 30~60 minutes. In the case of the complex programs, the duration of interventions was nine weeks, and the frequency and time per session varied. All of the exercise programs showed significant effects. Among the complex programs, two studies showed significant effects, but the remaining one study did not. Conclusion : Through this study, the types and effects of occupational therapy programs for the quality of life of the elderly were examined. Hereafter, studies of the development and to verify the effects of these programs should be actively carried out.