• Progress in Medical Physics
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• v.32 no.1
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• pp.1-17
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• 2021

The evolution of X-ray computed tomography (CT) has been based on the discovery of X-rays, the inception of the Radon transform, and the development of X-ray digital data acquisition systems and computer technology. Unlike conventional X-ray imaging (general radiography), CT reconstructs cross-sectional anatomical images of the internal structures according to X-ray attenuation coefficients (approximate tissue density) for almost every region in the body. This article reviews the essential physical principles and technical aspects of the CT scanner, including several notable evolutions in CT technology that resulted in the emergence of helical, multidetector, cone beam, portable, dual-energy, and phase-contrast CT, in integrated imaging modalities, such as positron-emission-tomography-CT and single-photon-emission-computed-tomography-CT, and in clinical applications, including image acquisition parameters, CT angiography, image adjustment, versatile image visualizations, volumetric/surface rendering on a computer workstation, radiation treatment planning, and target localization in radiotherapy. The understanding of CT characteristics will provide more effective and accurate patient care in the fields of diagnostics and radiotherapy, and can lead to the improvement of image quality and the optimization of exposure doses.

• Applied Microscopy
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• v.38 no.3
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• pp.275-278
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• 2008

Electron tomography (ET) is an electron microscopic technique for obtaining a 3-D image from any electron microscopy specimen and its application in biomedical science has been increased thanks to development of electron microscopy and related technologies during the last decade. There are few researches on ET in Korea during this period. Although the importance of ET has been recognized recently by many researchers, initial approach to electron tomographic research is not easy for beginners. The 4th International Congress on Electron Tomography (4 ICET) was held on Nov $5{\sim}8$, 2006, at San Diego. The program dealt instrumentation, reconstruction algorithm, visualization/quantitative analysis and electron tomographic presentation of biological specimen and nano particles. 1 have summarized oral presentations and analyzed the posters presented on the meeting. Cryo-electron microscopic system was popular system for ET and followed conventional transmission electron microscopic system. Cultured cell line and tissue were most popular specimens analyzed and microorganisms including bacteria and virus also constituted important specimens. This analysis provides a current state of art in ET research and a guide line for practical application of ET and further research strategies.

• Nuclear Engineering and Technology
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• v.54 no.2
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• pp.601-607
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• 2022

In recent years, monitoring of spent nuclear fuel inside dry cask storage has become an important area of national security. Muon tomography is a useful method for monitoring spent nuclear fuel because it uses high energy muons that penetrate deep into the target material and provides a 3-D structure of the inner materials. We designed a muon tomography system consisting of four 2-D position sensitive detector and characterized and optimized the system parameters. Each detector, measuring 200 × 200 cm², consists of a plastic scintillator, wavelength shifting (WLS) fibers and, SiPMs. The reconstructed image is obtained by extracting the intersection of the incoming and outgoing muon tracks using a Point-of-Closest-Approach (PoCA) algorithm. The Geant4 simulation was used to evaluate the performance of the muon tomography system and to optimize the design parameters including the pixel size of the muon detector, the field of view (FOV), and the distance between detectors. Based on the optimized design parameters, the spent fuel assemblies were modeled and the line profile was analyzed to conduct a feasibility study. Line profile analysis confirmed that muon tomography system can monitor nuclear spent fuel in dry storage container.

• Nuclear Engineering and Technology
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• v.55 no.3
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• pp.1009-1014
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• 2023

Muon tomography is a useful method for monitoring special nuclear materials (SNMs) such as spent nuclear fuel inside dry cask storage. Multiple Coulomb scattering of muons can be used to provide information about the 3-dimensional structure and atomic number(Z) of the inner materials. Tomography using muons is less affected by the shielding material and less harmful to health than other measurement methods. We developed a muon detector for muon tomography, which consists of a plastic scintillator, 64 long wavelength-shifting (WLS) fibers attached to the top of the plastic scintillator, and silicon photomultipliers (SiPMs) connected to both ends of each WLS fiber. The muon detector can acquire X and Y positions simultaneously using a position determination algorithm. The design parameters of the muon detector were optimized using DETECT2000 and Geant4 simulations, and a muon detector prototype was built based on the results. Spatial resolution measurement was performed using simulations and experiments to evaluate the feasibility of the muon detector. The experimental results were in good agreement with the simulation results. The muon detector has been confirmed for use in a muon tomography system.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.37 no.1
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• pp.27-36
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• 2000

As a potential approach for non-destructive testing of concrete structures, we evaluate the time-of-flight (TOF) ultrasound tomography technique In conventional X ray tomography, the reconstructed Image corresponds to the internal attenuation coefficient However, in TOF ultrasound tomography, the reconstructed Image is proportional to the retractive index of the medium Because refractive effects are minimal for X-rays, conventional reconstruction techniques are applied to reconstruct the Image in X-ray tomography However, since ultrasound travels in curved path, due to the spatial variations in the refractive index of the medium, the path must be known to correctly reconstruct the Image. Algorithm for determining the ultrasound path is developed from a Geometrical Optics point view and the image reconstruction algorithm, since the paths are curved It requires the algebraic approach, namely the ART or the SIRT Here, the difference between the computed and the measured TOP data is used as a basis, for the iteration process First the initial image is reconstructed assuming straight paths. It then updates the path based on the recently reconstructed image This process of reconstruction and path determination repeats until convergence The proposed algorithm is evaluated by computer simulations, and in addition is applied to a real concrete structure.

• Archives of Plastic Surgery
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• v.36 no.4
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• pp.428-431
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• 2009

Purpose: Blow out fracture resulting from facial trauma is of high frequency among facial bone fractures, and can cause severe complications. So, proper management and close observation after operation are needed. So far, Computed tomography has been the best choice in the evalution following orbit wall reconstruction. However, cost - effectiveness, accessibility to patients and hazard of radiation exposure of computed tomography require supplementary measure for the evaluation following orbit wall reconstruction. This study was performed to describe the effectiveness of ultrasonography in the evalution following orbit wall reconstruction. Methods: A retrospective study was performed on 40 patients who underwent orbit wall reconstruction from June, 2008 to July, 2008. The patients' ages ranged from 13 to 65 years (mean 27.5 years), and this group was compsoed of 27 male and 13 female patients. The follow up period ranged from 2 weeks to 28 weeks (mean 11weeks). Preoperatively, all fractures were diagnosed using computed tomography. Ultrasonography for all cases, and computed tomography for 2 cases were performed for evaluation following orbit wall reconstruction. Results: Reduction of herniated orbital soft tissue and orbit implant was identified by using ultrasonography in 38 cases out of 40 cases. In other cases which we could not identify the orbit implant, computed tomography was performed. Con clusion: Compared to computed tomography, ultrasonography is simple, inexpensive and convenient method. Ultrasonography can be used as supplementary measure to computed tomography in the evaluation following orbit wall reconstruction for elective patients.

• Journal of Biomedical Engineering Research
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• v.27 no.4
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• pp.189-196
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• 2006

Micro computed tomography (micro-CT) has been used for in vivo animal study owing to its noninvasive and high spatial resolution capability. However, the sizes of existing detectors for micro-CT systems are too small to obtain whole-body images of a small animal object with $\sim$10 micron resolution and a part of its bones or other organs should be extracted. So, we have introduced the zoom-in micro-tomography technique which can obtain high-resolution images of a local region of an live animal object without extracting samples. In order to verify our zoom-in technique, we performed in vivo animal bone study. We prepared some SD (Sprague-Dawley) rats for making osteoporosis models. They were divided into control and ovariectomized groups. Again, the ovariectomized group is divided into two groups fed with normal food and with calcium-free food. And we took 3D tomographic images of their femurs with 20 micron resolution using our zoom-in tomography technique and observed the bone changes for 12 weeks. We selected ROI (region of interest) of a femur image and applied 2D FDT (fuzzy distance transform) to measure the trabecular bone thickness. The measured results showed obvious bone changes and big differences between control and ovariectomized groups. However, we found that the reliability of the measurement depended on the selection of ROI in a bone image for thickness calculation. So, we extended the method to 3D FDT technique. We selected 3D VOI (volume of interest) in the obtained 3D tomographic images and applied 3D FDT algorithm. The results showed that the 3D technique could give more accurate and reliable measurement.

• 한국전자현미경학회:학술대회논문집
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• 2007.05a
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• pp.32-32
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• 2007

• Proceedings of the Korean Magnestics Society Conference
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• 2001.10a
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• pp.84-85
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• 2001

• Optical Science and Technology
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• v.10 no.1
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• pp.44-50
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• 2006