• 대한두개안면성형외과학회지
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• 제18권1호
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• pp.21-24
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• 2017

Background: In evaluation of craniosynostosis patients in terms of neurodevelopmental delay, positron emission tomography computed tomography (PET-CT) scan can be used to assess brain abnormalities through glucose metabolism. We aimed to determine the unnecessity of PET-CT in this study. Methods: Thirty-eight patients diagnosed with craniosynostosis who underwent distraction osteogenesis from October, 2010 to November, 2013 were reviewed. Magnetic resonance imaging (MRI) and PET-CT scan were carried out for evaluation of the brain structure and function, whereas X-ray and CT scan were taken for evaluation of the skull. Results: Nine patients reported abnormal MRI findings which were not significant, and five patients showed local problem on brain on PET-CT scan. No correlation was found among them. Conclusion: PET-CT evaluation of possible abnormal brain findings do not affect surgical planning or require additional therapy. Preoperative PET-CT scan is not the essential study to get any etiologic information of the disease consequences or to establish the treatment plan.

• 대한종양외과학회지
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• 제14권2호
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• pp.135-141
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• 2018

Purpose: Axillary lymph node dissection (ALND) and sentinel lymph node biopsy (SLNB) are important for staging of patients with node-positive breast cancer. However, these can be avoided in select micrometastatic diseases, preventing postoperative complications. The present study evaluated the ability of axillary lymph node maximum standardized uptake value (SUVmax) on positron emission tomography-computed tomography (PET-CT) to predict axillary metastasis of breast cancer. Methods: The records of invasive breast cancer patients who underwent pretreatment (surgery and/or chemotherapy) PET-CT between January 2006 and December 2014 were reviewed. ALNs were preoperatively evaluated by PET-CT. Lymph nodes were dissected by SLNB or ALND. SUVmax was measured in both the axillary lymph node and primary tumor. Student t-test and chi-square test were used to analyze sensitivity and specificity. Receiver operating characteristic (ROC) and area under the ROC curve (AUC) analyses were performed. Results: SUV-tumor (SUV-T) and SUV-lymph node (SUV-LN) were significantly higher in the triple-negative breast cancer (TNBC) group than in other groups (SUV-T: 5.99, P<0.01; SUV-LN: 1.29, P=0.014). The sensitivity (0.881) and accuracy (0.804) for initial ALN staging were higher in fine needle aspiration+PET-CT than in other methods. For PET-CT alone, the subtype with the highest sensitivity (0.870) and negative predictive value (0.917) was TNBC. The AUC for SUV-LN was greatest in TNBC (0.797). Conclusion: The characteristics of SUV-T and SUV-LN differed according to immunohistochemistry subtype. Compared to other subtypes, the true positivity of axillary metastasis on PET-CT was highest in TNBC. These findings could help tailor management for therapeutic and diagnostic purposes.

• 치과방사선
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• 제27권2호
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• pp.27-47
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• 1997

The purpose of this study was to evaluate the accuracy and usefulness of spiral tomography through the comparison and analysis of SCANORA cross-sectional tomographs and DentaScan computed tomographic images of dry mandibles taken by a SCANORA spiral tomographic machine and a computed tomographic machine. Thirty-one dry mandibles with full or partial edentulous areas were used. To evaluate the possible effect of location in the edentulous area, it was divided into 4 regions of Me (region of mental foramen), MI (the midportion between Me and M2), M2 (the midportion between mental foramen and mandibular foramen) and S (the midportion of the mandibular symphysis). A ZPC column (sized 4 mm x 5 mm) was seated on the edentulous regions of Me, MI, M2 and S using the acrylic stent. Then SCANORA spiral tomography and computed tomography were taken on the edentulous regions which contained the ZPC column. The ZPC columns and cross-sectional images of the mandible were measured in the radiographs by three observers and the differences between the two imaging modalities were analysed. The results were as follows: 1. In comparing the actual measurements of the ZPC column and measurements in the radiographs, the mean error of the DentaScan computed tomography was 0.07 mm in vertical direction and -0.06 mm in horiwntal direction, while the mean error of the SCANORA spiral tomography was 0.06 mm in vertical direction and -0.12 mm in horizontal direction. There was a significant difference between the two radiographic techniques in the horizontal measurement of the ZPC column of the symphysis region (p<0.05). But there was no significant difference in the measurements of other regions (p>0.05). 2. In measurements of the distance from the alveolar crest to the inferior border of the mandible (H), and of the distance from the alveolar crest to the superior border of the mandibular canal (Y), there was no significant difference between the two radiographic techniques (p>0.05). 3. In measurements of the distance from the lingual border of the mandible to the buccal border of the mandible (W), and of the distance from the lingual border of the mandible to the lingual border of the mandibular canal (X), there was a significant difference between the two radiographic techniques in measurements of the midportion between the mental foramen and the mandibular foramen (M2) (p<0.05). But there were no significant differences in measurements of the other regions of symphysis (S), mental foramen (Me), the first one-fourth portion between the mental foramen and the mandibular foramen (M1) (p>0.05). 4. Considering the mean range of measurements between observers, the measurements of SCANORA spiral tomography showed higher value than those of DentaScan computed tomography, except in measurements of symphysis (S). 5. On the detectability of the mandibular canal, there was no significant difference between the two radiographic techniques (p>0.05). In conclusion, SCANORA spiral tomography demonstrated a higher interobserver variance than that of DentaScan computed tomography for implant site measurements in the posterior edentulous area of the mandible. These differences were mainly the result of difficulty in the detection of the border of the mandible in SCANORA spiral tomography. But considering the cost and the radiation exposure, SCANORA spiral tomography can be said to be a relatively good radiographic technique for implant site measurement.

• 한국임상수의학회지
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• 제33권1호
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• pp.51-57
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• 2016

In this study, the features of canine lymphoma on fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) were evaluated in three small breed dogs. In case 1, ultrasonography and CT indicated neoplastic involvement of the sternal, right axillary, submandibular, lower cervical, tracheobronchial, mesenteric, and sublumbar lymph nodes; spleen; and liver. However, intense FDG uptake on PET/CT images was detected only for the lymph nodes and spleen. No FDG uptake by the liver was detected for case 1 despite the confirmation of lymphoma by cytology. In case 2, ultrasonography and CT indicated neoplastic involvement of the axillary, mesenteric, and sublumbar lymph nodes and the spleen, while intense FDG uptake on PET/CT images was detected for the axillary and a few mesenteric lymph nodes, and the spleen. FDG uptake was additionally observed from popliteal lymph nodes, however there was no uptake by the sublumbar lymph nodes and some mesenteric lymph nodes. In case 3, neoplastic changes in the splenic, mesenteric, and sublumbar lymph nodes and spleen were suspected on ultrasonography, and lower cervical and popliteal lymph node involvements were additionally detected on PET/CT. Compared to ultrasonography, repeated PET/CT showed increased FDG uptake by the lymph nodes at an earlier stage after chemotherapy in case 3. This study illustrated the features of PET/CT in canine lymphomas and compared those to ultrasonography and CT findings. FDG uptakes were not detected from some lesions which were suspected to be neoplastic involvement in case 1 and 2. We could not clearly explain the reason of this result in the present study because cytological or histological examination was not performed for lesions that showed different results on ultrasonography, CT, and PET/CT. Further studies on the subclassification of canine lymphoma and the sensitivity and specificity of PET/CT for the detection of canine lymphoma are required. PET/CT data can provide useful information for predicting the therapeutic response at an early stage after treatment.

• Journal of the Korean Wood Science and Technology
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• 제36권6호
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• pp.13-22
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• 2008

보드의 기계적 성질에 영향을 미치는 공극에 대하여 공극을 두가지로 분류하고 밀도에 따른 오에스비의 내부 공극구조의 특성에 대하여 살펴보고자 하였다. 스트랜드보드의 내부공극을 X-ray 단층촬영기로 측정하고 이미지분석 소프트웨어를 사용하여 밀도에 따른 공극의 분포와 공극의 함유량을 조사하였다. 측정 전에 보드의 밀도를 밀도측정기와 전건법으로 측정하였으며 이 두 방법에 의해 측정된 결과는 아주 높은 상관관계를 보여주었다. X-ray를 서로 다른 배율로 조사하여 획득한 이미지를 바탕으로 분석한 결과, 저해상도에서는 스트랜드간의 공극(macro-void)의 측정이 가능하나 스트랜드내의 미세공극(micro-void)은 이미지획득이 불가능하였다. 중해상도에서는 두가지 형태 모두의 이미지 획득이 가능하였고, 고해상도에서는 대부분의 미세공극 이미지의 획득이 가능하였다. 저배율을 채택하여 스트랜드간의 공극을 측정하고 스트랜드내의 미세공극은 관련식을 이용하여 추정하였다. 이를 통해 보드내부에 존재하는 스트랜드간의 공극분포를 파악할 수 있었으며 그 공극의 함유비율을 정확하게 산정할 수 있었다.

• 대한치과교정학회지
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• 제44권5호
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• pp.263-267
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• 2014

Objective: To three-dimensionally elucidate the effects of occlusal hypofunction on the periodontal ligament and alveolar bone proper of rat molars by micro-computed tomography (micro-CT). Methods: Occlusal function in the molar area was restricted by attaching an anterior bite plate on the maxillary incisors and a metal cap on the mandibular incisors of 5-week-old male Wistar rats for 1 week. The periodontal ligament space and alveolar bone proper around roots of the mandibular first molar were assessed by histology and micro-CT. Results: The periodontal ligament space was narrower and the alveolar bone proper was sparser and less continuous in the hypofunction group than in the control group. Further, both the volume of the periodontal ligament and the volumetric ratio of the alveolar bone proper to the total tissue in the region of interest were significantly lower in the hypofunction group (p < 0.05). Conclusions: Occlusal hypofunction induces atrophic changes in the periodontal ligament and alveolar bone proper of rat molars.

• 대한치과교정학회지
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• 제43권4호
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• pp.160-167
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• 2013

Objective: To evaluate the shapes and sizes of nasopharyngeal airways by using cone-beam computed tomography and to assess the relationship between nasopharyngeal airway shape and adenoid hypertrophy in children. Methods: Linear and cross-sectional measurements on frontal and sagittal cross-sections containing the most enlarged adenoids and nasopharyngeal airway volumes were obtained from cone-beam computed tomography scans of 64 healthy children ($11.0{\pm}1.8$ years), and the interrelationships of these measurements were evaluated. Results: On the basis of frontal section images, the subjects' nasopharyngeal airways were divided into the following 2 types: the broad and long type and the narrow and flat type. The nasopharyngeal airway sizes and volumes were smaller in subjects with narrow and flat airways than in those with broad and long airways (p < 0.01). Children who showed high adenoid-nasopharyngeal ratios on sagittal imaging, indicating moderate to severe adenoid hypertrophy, had the narrow and flat type nasopharyngeal airway (p < 0.01). Conclusions: Cone-beam computed tomography is a clinically simple, reliable, and noninvasive tool that can simultaneously visualize the entire structure and a cross section of the nasopharyngeal airway and help in measurement of adenoid size as well as airway volume in children with adenoid hypertrophy.

• Imaging Science in Dentistry
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• 제41권2호
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• pp.79-84
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• 2011

Purpose : The aim of the present study was to investigate the disagreement of cephalometric analysis depending on the reference determination of midsagittal plane on three-dimensional computed tomography. Materials and Methods : A total of 102 young women with class III dentofacial deformity were evaluated using three-dimensional computed tomography. The cranial and facial midsagittal planes were defined and the amounts of jaw deviation were calculated. The amounts of jaw deviation were compared with paired t-test (2-tailed) and Bland-Altman plot was drawn. Results : The landmark tracing were reproducible ($r{\ge}.978$). The jaws relative to the cranial midsagittal plane were 10-17 times more significantly deviated than to the facial midsagittal plane (P<.001). Bland-Altman plot demonstrated that the differences between the amounts of jaw deviation from two midsagittal planes were not normally distributed versus the average of the amounts of jaw deviation from two midsagittal planes. Conclusion : The cephalometric analyses of facial asymmetry were significantly inconsistent depending on the reference determination of midsagittal plane. The reference for midsagittal plane should be carefully determined in three-dimensional cephalometric analysis of facial asymmetry of patients with class III dentofacial deformity.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제36권2호
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• pp.78-86
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• 2010

Introduction: Cone beam computed tomography (CBCT) has various advantages and is used favorably in many fields in dentistry. Especially, CBCT is being used as basic diagnostic tool for 3-dimensional analysis in orthognathic patient. Two-dimensional cephalograms can be synthesized from CBCT digital imaging and communications in medicine (DICOM) data. In this study, conventional cephalograms and CBCT were taken simultaneously, and representative landmarks were located and analyzed in its accuracy and reproducibility. Materials and Methods: Ten patients who had orthognathic surgery in Wonkwang University Daejeon Dental Hospital participated in this study. For each patient, CBCT and conventional cephalogram was taken. By using Ondemand (Cybermad, Korea), 2-dimensional cephalograms was established on CBCT. In addition, 19 landmarks were designated and measured by 3 orthodontists twice a week. After these landmarks were transferred to a coordinate, distance of landmark and axis, standard error, distribution degree were measured, compared and analyzed. Results: Comparing the CT ceph group and conventional cephalogram group, CT ceph group had shown shorter distance of landmark and axis in S, Hinge axis, Bpt, Ba, Or, Corpus left. Standard error of the mean shows that CT ceph group has better reproducibility in Or, Corpus left, Hinge axis at X axis and Na, U1R, U1T, Bpt, PNS, Ba Corpus left, Hinge axis at Y axis. In both groups, mean error was less than 1.00 mm, no significant difference were found between CT ceph group and conventional cephalogram group in all measurements. Furthermore, comparing two groups, each 17 landmarks out of 19 had its characteristic in distribution degree. Conclusion: No significant difference were found between CBCT composed cephalographic radiograph and conventional cephalograghic radiograph, clinical application may be possible if improved.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2005년도 제25회 추계학술대회논문집
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• pp.469-474
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• 2005

전산화 단층촬영법을 이용하여 탄소/탄소 목삽입재의 밀도 분포를 평가 하였다. 전산화 단층촬영 법의 Beam hardening, 전기적 잡음 및 산란 X-ray의 영상을 토정하고 신호 대 잡음비를 높여 최적화할 때 측정된 제작된 탄소/탄소 복합재료의 밀도는 98.74%의 신뢰도 수준에서 ${\pm}0.01g/cm^3$ 분포를 갖는 것으로 평가 되었다. 전산화 단층촬영 결과의 검증은 탄소/탄소 목삽입재를 절단하며 수침법에 의한 밀도 측정과 주사전자현미경 관찰을 통하여 수행되었으며 단층촬영결과는 수침법에 의한 밀도 분포와 주사전자현미경의 결과와 일치하였다.