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The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients

  • Yang, Chae Eun (Institute for Human Tissue Restoration, Department of Plastic and Reconstructive Surgery, Severance Hospital, Yonsei University College of Medicine) ;
  • Park, Eun Kyung (Department of Pediatric Neurosurgery, Severance Children's Hospital, Yonsei University College of Medicine) ;
  • Lee, Myung Chul (Department of Plastic and Reconstructive Surgery, Konkuk University School of Medicine) ;
  • Shim, Kyu Won (Department of Pediatric Neurosurgery, Severance Children's Hospital, Yonsei University College of Medicine) ;
  • Kim, Yong Oock (Institute for Human Tissue Restoration, Department of Plastic and Reconstructive Surgery, Severance Hospital, Yonsei University College of Medicine)
  • Received : 2016.12.20
  • Accepted : 2017.02.07
  • Published : 2017.03.20

Abstract

Background: In evaluation of craniosynostosis patients in terms of neurodevelopmental delay, positron emission tomography computed tomography (PET-CT) scan can be used to assess brain abnormalities through glucose metabolism. We aimed to determine the unnecessity of PET-CT in this study. Methods: Thirty-eight patients diagnosed with craniosynostosis who underwent distraction osteogenesis from October, 2010 to November, 2013 were reviewed. Magnetic resonance imaging (MRI) and PET-CT scan were carried out for evaluation of the brain structure and function, whereas X-ray and CT scan were taken for evaluation of the skull. Results: Nine patients reported abnormal MRI findings which were not significant, and five patients showed local problem on brain on PET-CT scan. No correlation was found among them. Conclusion: PET-CT evaluation of possible abnormal brain findings do not affect surgical planning or require additional therapy. Preoperative PET-CT scan is not the essential study to get any etiologic information of the disease consequences or to establish the treatment plan.

Keywords

References

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  1. Intracranial pressure, brain morphology and cognitive outcome in children with sagittal craniosynostosis vol.36, pp.4, 2020, https://doi.org/10.1007/s00381-020-04502-z