• Nuclear Engineering and Technology
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• 제38권3호
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• pp.239-250
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• 2006

Computational anthropomorphic phantoms are computer models of human anatomy used in the calculation of radiation dose distribution in the human body upon exposure to a radiation source. Depending on the manner to represent human anatomy, they are categorized into two classes: stylized and tomographic phantoms. Stylized phantoms, which have mainly been developed at the Oak Ridge National Laboratory (ORNL), describe human anatomy by using simple mathematical equations of analytical geometry. Several improved stylized phantoms such as male and female adults, pediatric series, and enhanced organ models have been developed following the first hermaphrodite adult stylized phantom, Medical Internal Radiation Dose (MIRD)-5 phantom. Although stylized phantoms have significantly contributed to dosimetry calculation, they provide only approximations of the true anatomical features of the human body and the resulting organ dose distribution. An alternative class of computational phantom, the tomographic phantom, is based upon three-dimensional imaging techniques such as magnetic resonance (MR) imaging and computed tomography (CT). The tomographic phantoms represent the human anatomy with a large number of voxels that are assigned tissue type and organ identity. To date, a total of around 30 tomographic phantoms including male and female adults, pediatric phantoms, and even a pregnant female, have been developed and utilized for realistic radiation dosimetry calculation. They are based on MRI/CT images or sectional color photos from patients, volunteers or cadavers. Several investigators have compared tomographic phantoms with stylized phantoms, and demonstrated the superiority of tomographic phantoms in terms of realistic anatomy and dosimetry calculation. This paper summarizes the history and current status of both stylized and tomographic phantoms, including Korean computational phantoms. Advantages, limitations, and future prospects are also discussed.

• 대한방사선기술학회지:방사선기술과학
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• 제40권1호
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• pp.13-18
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• 2017

본 논문은 GATE (geant4 application for tomographic emission) 시뮬레이션을 이용하여 다양한 모양과 재질의 팬텀에서 CTDI (computed tomography dose index)를 평가하였다. GATE 시뮬레이션은 실린더 기둥, 타원 기둥과 육각 기둥 형태와 물, PMMA (polymethyl methacrylate), polyethylene 그리고 polyoxymethylene 재질의 다양한 지름(1 ~ 50 cm)의 팬텀을 모사하여 $CTD_{I100center}$ 값을 비교하였다. 120 kV, 200 mAs에서 실린더 기둥, 타원 기둥과 육각 기둥의 $CTDI_{100center}$ 값은 각각 11.1, 13.4 그리고 12.2 mGy이었다. 이 결과는 동일 볼륨이지만 팬텀의 형태에 따라 $CTDI_{100center}$ 값의 차이가 있음을 알 수 있다. 그리고 물, PMMA 그리고 polyoxymethylene 팬텀의 $CTDI_{100center}$ 값을 비교했을 때 물질의 밀도가 높을수록 상대적으로 $CTDI_{100center}$ 값이 낮게 측정되었다. 하지만 polyethylene의 경우 지름이 15 cm ($CTDI_{100center}$ : 35.0 mGy) 이 상에서는 PMMA 보다 $CTDI_{100center}$ 값이 증가하였다. 그리고 30 cm ($CTDI_{100center}$ : 17.7 mGy) 이 상의 지름에서는 물 보다 더 높은 $CTDI_{100center}$ 값을 보였다. 본 실험을 통해 팬텀의 재질 및 모양에 따른 $CTDI_{100center}$ 값을 GATE 시뮬레이션을 이용하여 평가하였다. CT 선량 평가시 다양한 재질 및 인체에 가까운 모양의 팬텀을 사용함으로써 좀 더 정확한 환자선량을 평가할 수 있을 것이다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2006년도 제33회 추계학술대회 발표논문집
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• pp.124-124
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• 2006

• 한국방사선학회논문지
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• 제13권5호
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• pp.773-778
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• 2019

X-선을 이용한 영상은 진단에 필수적인 요소지만 영상에서의 noise발생이 불가피하다. 이를 보완하기 위해 환자의 피폭선량은 낮추면서 영상의 질은 높여주는 total variation (TV) 알고리즘이 제시되었다. 본 연구의 목적은 시뮬레이션을 통해 부가 여과판의 두께에 따라 방사선 영상 촬영 시 영상의 화질에 미치는 영향을 확인하고, TV 알고리즘의 유용성을 평가하는 것이다. 부가 여과판의 두께변화에 따른 각 알고리즘 적용 시 Geant4 Application for Tomographic Emission (GATE) 시뮬레이션 영상을 이용하여 Polymethylmethacrylate(PMMA) 팬텀의 실제 크기, 모양과 재질을 동일하게 하고 대조도 대 잡음비 (contrast to noise ratio, CNR)과 변동계수 (coefficient of variation, COV)값을 비교하였으며 그 결과 TV 알고리즘 적용 시 CNR 값이 가장 높고 COV 값이 가장 낮다는 것을 확인할 수 있었다. 또한, 모든 알고리즘에서 0 mmAl을 사용할 경우 가장 우수한 CNR과 COV값을 얻을 수 있었다.

• Nuclear Engineering and Technology
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• 제53권6호
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• pp.1947-1954
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• 2021

In the nuclear medicine imaging, quality control (QC) process using quadrant bar phantom is fundamental aspect of evaluating the spatial resolution. In addition, QC process of gamma camera is performed by daily or weekly. Recently, Monte Carlo simulation using the Geant4 application for tomographic emission (GATE) is widely applied in the pre-clinical nuclear medicine field for modeling gamma cameras with pixelated cadmium telluride (CdTe) semiconductor detector. In this study, we modeled a pixelated CdTe semiconductor detector and quadrant bar phantom (0.5, 1.0, 1.5, and 2.0 mm bar thicknesses) using the GATE tool. Similarity analysis based on correlation coefficients and peak signal-to-noise ratios was performed to compare image qualities for various source to collimator distances (0, 2, 4, 6, and 8 cm) and collimator lengths (0.2, 0.4, 0.6, 0.8, and 1.0 cm). To this end, we selected reference images based on collimator length and source to collimator distance settings. The results demonstrate that as the collimator length increases and the source to collimator distance decreases, the similarity to reference images improves. Therefore, our simulation results represent valuable information for the modeling of CdTe-based semiconductor gamma imaging systems and QC phantoms in the field of nuclear medicine.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1979년도 하계 전자.전기연합학술발표회논문집
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• pp.164-165
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• 1979

Two dimensional kernels which reconstruct the tomographic image from the blurred one formed by simple back-projection are investigated and their performances are compared. These kernels are derived from tile point spread function of the tomographic system and have the form of a ramp filter modified by several window functions to suppress ringing in the reconstruction. Computer simulation using a computer generated phantom image data with different correction functions(kernels) has been carried out. In this simulation, filtering in frequency domain by 2-D FFT technique or in space domain by 2-D direct convolution is considered. It is found that the-computation time required for real space convolution technique is much larger than that of Fourier 2-D filtering technique in the pratical situation.

• 한국방사선학회논문지
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• 제13권3호
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• pp.453-458
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• 2019

본 연구에서는 Geant4 application for tomographic emission (GATE) 시뮬레이션 프로그램을 통해 설계 된 male adult mesh (MASH) 팬텀의 영상을 획득한 후 다양한 필터링 인자가 설정된 FNLM 노이즈 제거 알고리즘을 적용함으로써 그에 따른 영상 특성의 경향성을 알아보고자 한다. 이를 위해 GATE 시뮬레이션 프로그램을 통해 인체를 모사할 수 있는 MASH 팬텀을 설계하였다. 또한, 설계된 MASH 팬텀을 기반으로 MATLAB 프로그램을 통해 복부영상을 획득한 후 0.005의 $\sigma$ 값을 갖는 Gaussian noise를 추가하여 열화영상을 모델링하였다. 모델링 된 열화영상으로부터 제안하는 FNLM 노이즈 제거 알고리즘의 필터링 인자를 각각 0.005, 0.01, 0.05, 0.1, 0.5, 1.0 으로 설정하여 적용하였으며, 정량적 평가를 위해 FNLM 노이즈 제거 알고리즘이 적용된 영상들로부터 각각의 coefficient of variation (COV), signal to noise ratio (SNR) 그리고 contrast to noise ratio (CNR)을 측정하였다. 결과적으로, 0.05의 필터링 인자가 적용된 영상에서 가장 개선된 COV, SNR 그리고 CNR 값을 보였다. 특히, COV는 설정된 필터링 인자가 증가함에 따라 감소하였으며, 0.05 값 이후부터 거의 일정한 값을 나타내었다. 또한, SNR 및 CNR의 경우 필터링 인자가 증가함에 따라 증가하였으며, 0.05 값 이후부터 감소하는 경향을 보였다. 결론적으로, 열화 영상으로부터 FNLM 노이즈 제거 알고리즘 적용 시 적합한 필터링 인자를 설정해야 함이 증명되었다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2009년도 제38회 동계학술대회 초록집
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• pp.472-472
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• 2010

The tomography has played a key role in tokamak plasma diagnostics for image reconstruction. The Phillips-Tikhonov (P-T) regularization method was attempted in this work to reconstruct cross-sectional phantom images of the plasma by minimizing the gradient between adjacent pixel data. Recent studies about the comparison of the several tomographic reconstruction methods showed that the P-T method produced more accurate results. We have studied existing Laplacian matrix used in Phillips-Tikhonov regularization method and developed modified Laplacian matrix (Modified L). The comparison of the reconstruction result by the modified L and existing L showed that modified L produced more accurate result. The difference was significantly pronounced when a portion of plasma was reconstructed. These results can be utilized in the Edge Plasma diagnostics; especially in divertor diagnostics on tokamak a large impact is expected. In addition, accurate reconstruction results from received data in only one direction were confirmed through phantom test by using P-T method with modified L. These results can be applied to the tangentially viewing pin-hole camera diagnostics on tokamak.

• Journal of Mechanical Science and Technology
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• 제17권4호
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• pp.571-580
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• 2003

Tomography has been investigated to observe bubble behaviors in two-phase flows. A bubbly flow and an annular flow have been reconstructed by tomography methods such as an algebraic reconstruction technique (ART) and a multiplicative algebraic reconstruction technique (MART) . Computer synthesized phantom fields have been used to calculate asymmetric density distributions for limited cases of 3, 5, and 7 projection angles. As a result of comparison of two tomography methods, the MART method has shown a significant improvement in the reconstruction accuracy for analysis of the two-phase flows.

• Imaging Science in Dentistry
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• 제53권4호
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• pp.345-353
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• 2023

Purpose: The objective of this study was to propose a method for developing a clinical phantom to reproduce various diseases that are clinically prevalent in the field of dentistry. This could facilitate diverse clinical research without unnecessarily exposing patients to radiation. Materials and Methods: This study utilized a single dry skull, which was visually and radiographically examined to evaluate its condition. Existing lesions on the dry skull were preserved, and other relevant lesions were artificially created as necessary. These lesions were then documented using intraoral radiography and cone-beam computed tomography. Once all pre-existing and reproduced lesions were confirmed by the consensus of 2 oral and maxillofacial radiologists, the skull was embedded in a soft tissue substitute. To validate the process, cone-beam computed tomography scans and panoramic radiographs were obtained of the fabricated phantom. All acquired images were subsequently evaluated. Results: Most lesions could be identified on panoramic radiographs, although some sialoliths and cracked teeth were confirmed only through cone-beam computed tomographic images. A small gap was observed between the epoxy resin and the bone structures. However, 2 oral and maxillofacial radiologists agreed that this space did not meaningfully impact the interpretation process. Conclusion: The newly developed phantom has potential for use as a standardized phantom within the dental field. It may be utilized for a variety of imaging studies, not only for optimization purposes, but also for addressing other experimental issues related to both 2- and 3-dimensional diagnostic radiography.