• 보건교육건강증진학회지
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• 제30권4호
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• pp.9-16
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• 2013

Objectives: The purpose of this manuscript was to review Intersectoral Collaboration policies for Tobacco Control. Methods: The author selected the WHO Framework Convention on Tobacco Control and adopted guidelines, and reviewed intersectoral and multisectoral collaboration policy recommendations. Results: There are 11 chapters and 38 articles in the Convention. In the Demand reduction policies included price and non price measures. The author selected a few non price measures for cross sectoral collaboration examples. They are protection from exposure to tobacco emission, education and communication, banning advertising, promotion and sponsorship of tobacco products, and offering treatment to tobacco use cessation. Inter sectoral and multi sectoral approaches could increase effectiveness, and better outcome of the tobacco control policy for implementation of many different articles of FCTC. Conclusions: It is important to give a specific role in structures of different government sectors and infrastructure for intersectoral collaboration. In addition, the role of civil society is very important for implementation of tobacco control policy effectively, and governments have to support the civil society for anti-smoking activities and campaigns.

• 한국연초학회지
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• 제8권2호
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• pp.59-66
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• 1986

The Pyrolytic behavior of glycyrrhizic acid and glycyrrhetini c acid, which are natural flavorants for manufactured cigarettes was observed to find its contribution to the smoke composition. Pyrolyzates of them at 800t were identified using a gas chromatography and a mass spectrometer. According to the analysis of the pyrolytic Products, 43 different compounds were identified Among them the aromatic hydrocarbon compounds were found to be the major products.

• 한국연초학회지
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• 제6권2호
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• pp.131-139
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• 1984

The pyrolytic behavior of vanillin, a flavorant for manufactured cigarettes, was examined to find its contribution to the smoke composition. Vanillin was pyrolyzed at various temperatures (500-$900^{\circ}C$) in a stream of nitrogen. Pyrolytic products at $800^{\circ}C$ were identified with GC/MS. As increasing temperature, pyrolytic products did not appear with qualitative differences. Component analysis of the resulting products showed that 24 compounds were identified. and phenolic compounds were major products. The pyrolytic pathway of vanillin was also discussed.

• 한국연초학회지
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• 제9권2호
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• pp.77-85
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• 1987

$\alpha$, $\beta$-4.8.13-Duvatriene-1, 3-diols was identified as the major component of diterponoid extracted from Nicotiana Tabacum L. The isolated duvatriendiol was thermolyged at 300'c under a stream of nitrogen. The approximately 20 compounds were separated from the thermolyzates and the 9 compounds of them were identified with GC/MS. However, the thermolyzates identified in this study differed in distribution from the products under the condition of a different temperature or photooxidation.

• 한국연초학회지
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• 제7권1호
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• pp.75-84
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• 1985

A strain of Trichoderm sp. J-30 which strongly products cellulase to reduce the content of cellulose in the stem of leaf tobacco was isolated from leaf tobaco. The Trichoderma sp. J-30 was identified as Trochoderma voride. The cellulase from this strain was purified with the physico-chemical methods and treated in the culled stem of leaf tobacco. The results obtained were summarized as follows. 1. Optimal pH of the enzyme was at pH 5.0. 2. The enzyme shooed a higher activity at $40^{\circ}C$ and its thermal stability began to decrease at $60^{\circ}C$. 3. The enzyme activity was promoted by the metal ions such as $Ca^{2+}, Mg^{2+}, Pb^{2+}and\;Zn^{2+}.$ 4. When the culled stem of leaf tobacco was applied with the 3% of the enzyme solution at $40^{\circ}C$ for 3 days. 15 to 17% of cellulose contents decreased, 12 to 13% of total sugar increased and the filling power was increased by 10-13% in the sample.

• 한국연초학회지
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• 제23권1호
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• pp.53-59
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• 2001

To decrease of deviations from target specifications and excessive variability around targe, we exclusively designed statistical process control system involving general manager and expert tool for cigarette manufacturing process. This system is a unique programming environment for the development of total process control software including various control charts according to data type and process capability analysis. Also this system includes the statistical analysis module to analyze defective causes immediately when inferior products are made and the module to offer regular reports. This system is customized considering the manufacture environment based on the opinions of workers.

• 한국환경보건학회지
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• 제49권2호
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• pp.118-128
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• 2023

Background: The use of heated tobacco products (HTP) causes many adverse health effects. Although the use of HTP by adolescents is prevalent worldwide, research related to it is very limited. There is a considerable lack of research related to the current HTP use rather than ever-HTP use. In particular, research related to predictive factors for current HTP use in adolescents is scarce. Objectives: The purpose of this study was to analyze related characteristics according to the current use of HTP among South Korean adolescents. Methods: This was a cross-sectional study that used data from the Seventeenth Korean Youth Risk Behavior Web-based Survey (KYRBWS). A total of 54,848 students in 2021 were included in this study. Chi-square-test, multiple logistic regression analysis, and chi-square test for trend were used for analyzing related characteristics according to use of HTP. Results: Overall, 715 (1.3%) students responded as having used HTP during the last 30 days among the 54,848 students. It was found that residence type, subjective body type recognition, subjective health recognition, alcohol use, habitual drug experience, close friend current smoking, and conventional cigarette smoking were significantly associated characteristics with the current use of heated tobacco products. Comparing 'very thin recognition' with 'very fat recognition', the adjusted odds ratio (OR) was 1.93 (95% confidence interval [CI]: 1.29~2.87) for current use of HTP. Additionally, comparing 'very unhealthy recognition' with 'very healthy recognition', the aOR was 3.82 (95% CI: 2.40~6.07) for current use of HTP. Conclusions: Based on these results, residence type, subjective body type recognition, subjective health recognition, alcohol use, habitual drug experience, close friend current smoking, and conventional cigarette smoking were associated with significantly increased odds of current HTP use. Therefore, the results of this study can provide useful evidence about adolescent behaviors in predicting current HTP use.

• 생명과학회지
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• 제34권5호
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• pp.320-332
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• 2024

본 연구는 연소담배와 비교해 서로 다른 가열담배(heated tobacco products, HTPs) 사용 시 혈역학적 지표들의 급성 반응을 비교하고, 급성 HTPs 에어로졸 노출이 심장 자율신경조절(cardiac autonomic regulation, CAR)에 미치는 영향을 탐색하려는 목적으로 수행되었다. 또한, 서로 다른 연초 스틱 간 급성 심혈관 효과의 비교 검증을 목표로 하위연구를 설계했다. 외관상 건강한 남성 흡연자 16명은 개방표지, 무작위 교차시험으로, 최소 48시간 세척기간과 함께 비-흡연(non-smoking, NS), 담배 흡연 및 서로 다른 두 가지 HTPs 사용 세션을 각각 수행했다. 하위연구는 NS와 함께 서로 다른 두 가지 연초 스틱 간 급성 심혈관 효과를 비교하기 위해, 참여자 중 8명을 대상으로 실시되었다. 수축기와 확장기 혈압 및 CAR을 반영하는 심박변이도(heart rate variability, HRV)가 각 세션 시작 전, 제품 사용 중 그리고 사용 후 30분까지 평가되었다. NS 동안 혈역학적 변화는 통계적 차가 없었으나, HTPs 에어로졸에 급성 노출은 담배 연기와 상응하는 수축기와 확장기 혈압의 유의한 증가를 초래했으며, 이들 지표에서 HTPs 기기 간 통계적 차는 없었다. 연소담배와 HTPs 사용 후 통계적으로 유의한 심장 교감신경활동(cardiac sympathetic nerve activity, CSNA)의 급성 증가와 심장 미주신경 긴장도(cardiac vagal tone, CVT)의 급격한 저하가 나타났다. 사용 기기와 독립적으로 HTPs 사용에 따른 CSNA와 CVT 반응은 연소담배와 통계적 차가 없었다. 서로 다른 두 가지 연초 스틱은 NS와 비교해 혈역학적 지표들의 유의한 증가를 유도했으나, 연초 스틱 간 통계적 차는 없었다. CVT는 두 가지 연초 스틱 사용에 따라 유의하게 감소했으며, 연초 스틱의 종류에 따라 CVT 저하에 통계적 차가 있었다. 이상의 결과들은 HTPs 에어로졸 노출이 사용 기기와 독립적으로 연소담배와 동등한 급성 심혈관 효과를 유도할 수 있으며, 연초 스틱의 종류에 따라 급성 CAR 저하가 강화될 수 있음을 시사한다.

• 한국환경성돌연변이발암원학회지
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• 제22권2호
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• pp.97-105
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• 2002

Nowadays a huge variety of products that aim to assist to quit smoking or reduce addictive symptoms are developed and manufactured with safety evaluation, but the safety of the most recent products of interest which do not contain tobacco and nicotine, and shape cigarettes is not evaluated and guaranteed relatively. This study was carried out to evaluate the single and repeated dose inhalation toxicity and genotoxicity of H menthol (Nicotine free-tobacco free) herbal cigarettes provided by Cigastop Ltd. in ICR mice. In this study, doses which we determined to expose to mice were 40 cigarettes for 6 hours a day to mice in single dose and 20 (high dose), 10 (middle dose) and 5 cigarettes (low dose) a day for 28 days in repeated dose inhalation toxicity, in vivo chromosome aberration test and micronucleus test. The particulate substances from H menthol herbal cigarettes also were gathered and used in the Salmonella typhimurium/microsome assay (Salmonella test; Ames test). We could find neither significant changes between control and treatment groups nor dose-response effects of test material at all except serum Ca level of female middle dose treatment group in repeated dose inhalation toxicity test. In conclusion, H menthol herbal cigarettes, when applied clinically intended dose we used, might not show any toxic and/or mutagenic effect.

• 한국연초학회지
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• 제19권2호
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• pp.159-161
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• 1997

A study on the optimal drying condition by a vacuum drying oven was done using shredded tobacco lamina and commercial cigarettes ('This'). Changes in the mass of the experimental material were monitored for about 50 hrs at 6 different temperatures (5$0^{\circ}C$~10$0^{\circ}C$, 1$0^{\circ}C$ stepwise) while continuously operating a vacuum pump. After 30 hrs, small amount of samples from each material were taken sequentially to monitor changes in moisture content using a Karl-Fischer method (Metrohm KF 701 Titrino). Absolute moisture contents calculated from the measurements indicated an ideal data distribution could be obtained by drying at temperatures between 7$0^{\circ}C$~8$0^{\circ}C$. Results from cigarette products which contains humectant and tobacco lamina without it were compared.