• 제목/요약/키워드: ToMV

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MCNP-code를 이용한 의료용 선형가속기의 타깃 재질에 따른 광자선 특성 분석 (Analysis of the Photon Beam Characteristics by Medical Linear Accelerator According to Various Target Materials using MCNP-code)

  • 이동연;박은태;김정훈
    • 한국방사선학회논문지
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    • 제11권4호
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    • pp.197-203
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    • 2017
  • 의료용 선형가속장치의 두부 구성요소 중 광자 발생의 원인이 되는 타깃에 대한 연구로써, 타깃의 재질에 따른 광자를 분석하여 타깃 재질 별 발생하는 광자특성에 대한 기초자료를 제시하고자 한다. 본 연구에서는 몬테카를로 방식을 바탕으로 한 MCNPX를 사용하여 타깃 재질에 따른 6, 15 MV의 광자 특성을 비교분석하였다. 타깃 재질 별 평균에너지는 6 MV에서 1.69 ~ 1.84 MeV, 15 MV에서는 3.38 ~ 3.56 MeV로 분석되었다. Flux는 6 MV에서 $1.64{\times}10^{-5}{\sim}1.80{\times}10^{-5}{\sharp}/cm^2/e$, 15 MV는 $1.76{\times}10^{-4}{\sim}1.85{\times}10^{-4}{\sharp}/cm^2/e$로 계산되었다. 결과를 분석하면, 타깃 재질이 고원자번호일수록 평균에너지와 Flux가 증가하는 것으로 평가다. 본 연구를 바탕으로 광자의 물리적 특성에 대한 기초적인 자료를 제시할 수 있었으며, 추후 타깃 선정 시 경제성, 효율성은 물론 물리적 측면을 고려할 수 있어 적절한 선택을 할 수 있을 것으로 판단된다.

전류방식기법에 의한 다치론이계의 구성에 관한 연구 (A Study on the Synthesis of Multivalued Logic System Using Current-Mode Techniques)

  • 한만춘;신명철;박종국;최정문;김락교;이래호
    • 전기의세계
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    • 제28권1호
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    • pp.43-52
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    • 1979
  • Recently, interest in multivalued(MV) logic system has been increased, despites the apparent difficulties for practical application. This is because of the many advantages of the MV compared with the 2-valued logic systems, such as; (a) higher speed of arithmetical operation on account of the smaller number of digits required for a given data, (b) better utilization of data transmission channels on account of the higher information contents per line, (c) potentially higher density of information storage. This paper describes a MV switching theory and experimental MV logic elements based on current-mode logic technique. These elements tried were a 3-stable pulse generator, a ternary AND, a ternary OR, a MT circuit and a ternary inverter. Tristable flops which are indispensable for constituting a ternary shift register are synthesized using these gates. A BCD to TCD decoder, and vice versa, are proposed by using a ternary inverter and some binary gates. Thus, the feasibility of a large scale MV digital system has been demonstrate.

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$1{\sim}30MHz$ 광대역 전력선 통신을 위한 고압 배전선의 임피던스 특성 측정 및 해석 (Impedance measurement and analysis of overhead medium voltage power lines for broad band power line communication (BPLC))

  • 박영진;이재조;김관호;이원태
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2005년도 제36회 하계학술대회 논문집 C
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    • pp.2345-2347
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    • 2005
  • In this paper, impedance characteristics of overhead medium-voltage (MV) power lines is reported for power line communication (PLC) over an MV power line network. For analysis, a two-port equivalent network model of MV power lines is derived. By applying the transmission line theory, reflection behavior and impedance of power lines are investigated. For verification, impedance of power lines is measured at a test field for an MV PLC. The results show that impedance of MV power lines is between $200{\Omega}$ and $300{\Omega}$ and converges to a half of their characteristic impedance.

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User experience of MV2000-MT (SU:M2)® as a Mechanical Ventilator: A Comparative Clinical Study on Usability, Safety, and Medical Staff Satisfaction

  • Jeon, Soeun;Kim, Hae Kyu;Lee, Dowon;Kim, Hyae Jin;Park, Eun Ji
    • 대한의용생체공학회:의공학회지
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    • 제40권6호
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    • pp.260-267
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    • 2019
  • In the present study, we aimed to demonstrate that MV2000-MT(SU:M2)® (MV, MEK-ICS, Paju, Korea), a domestic ventilator, is not inferior in terms of usability, safety, and medical staff satisfaction as compared to Hamilton G5 (G5, Hamilton Medical AG, Rhäzuns, Switzerland). A total of 39 patients who applied MV (group M) or G5 (group H) were included in the study sample. Usability was evaluated by the following factors: the number of alarm errors, replacement requirement of breathing circuit, replacement requirement of a right-angle connector, and ease of ventilator weaning. For safety evaluation, the number of ventilator replacements due to malfunction of the ventilator was evaluated. Items for medical staff satisfaction survey were as follows: the number of MV and G5 uses, hardware, and software assessment. In the usability evaluation, the replacement requirement of the right-angle connector was lower in Group M than in Group H (mean ± standard deviation, Group M: 7.39 ± 6.72, Group H: 14.19 ± 10.24, p = 0.021); however, the evaluations of other parts were not significantly different between the two groups. The number of ventilator replacements due to a malfunction of the ventilator did not differ between two groups. The number of MV and G5 uses was 3.0 [3.0-4.0] and 10.0 [5.0-10.0] (median [interquartile range], p < 0.001). Overall, the mean medical staff satisfaction score of Hamilton G5 was higher than that of MV2000-MT(SU:M2)®. The usability of MV is comparable to that of G5. However, medical staff satisfaction with Hamilton G5 was higher than that with MV2000-MT(SU:M2)®, and this difference could be due to the difference in the number of uses. In order to improve the penetration rate of the domestic mechanical ventilator, it is necessary to find ways to increase familiarity of medical staff with domestic mechanical ventilators.

Mevatron KD 8067 선형가속기의 23 MV 광자선의 특성 (Characteristics of 23 MV Photon Beam from a Mevatron KD 8067 Dual Energy Linear Accelerator)

  • 김옥배;최태진;김영훈
    • Radiation Oncology Journal
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    • 제8권1호
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    • pp.115-124
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    • 1990
  • 고 에너지 23MV광자선의 특성 중 임상적용에 중요한 심부선량 백분율, 조직-최대선량비 (TMR), 산란-최대선량비 (SMR), 표면선량 및 출력선량 보정계수등의 변수가 이온전리 (IC-10)함 및 평행 평판전리 (PS-033)함에 의해 측정 조사되었다. 명목상의 23 MV X-선에 대한 가속에너지는 $18.5\pm0.5$ MV로 측정되었다. Mevatron KD 8067의 23 MV X-선의 중심선속의 반가층이 기하학적인 좁은 선속으로 측정되었으며 반가층의 두께는 $24.5\;g/cm^2$이었다. 조직-최대선량비는 심부선량백분율표에서 구해졌으며, 실측치와 비교한 결과 각 조사면의 크기와 깊이에서 약간의 차이를 보였으나 평균 $0.7\pm0.5$의 오차를 나타내고 있어 계산에 의한 TMR 값과 잘 일치함을 보였다. 조사면 $0\times0\;cm^2$의 TMR 값은 zero 조사면의 유효감약계수에 의한 값과, 각 조사면의 조직-최대 선량비로 부터 비선형최소자승법에 의해 구해진 유효선흡수계수 및 반가층 측정에 의한 유효선흡수 계수에 의한 값들로 비교되었으며, $\mu=0.0283{\pm}0,0002cm^{-1}$을 보였고, 세 방법 모두 오차범위내에서 잘 일치됨을 보였다. 한편, 불규칙 조사면의 선량계산에 이용될 SMR은 조사면의 반경 50cm까지 계산되어 대형 조사 면에서도 선량율 산출이 이루어지도록 하였다. Mevatron KD 8067의 23 MV X-선의 조직 표면선량은 SSD 100 cm, 1$10\times10\;cm^2$의 조사면에서 최대조직선량율의 $9.6\%,\;25\times25\;cm^2$에서는 $25.4\%$를 보였다.

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10 MeV의 전자선이 텅스텐 표적에 충돌하여 생성되는 광자선 스펙트럼의 계산 (Calculation of Photon Spectra from the Tungsten Target for 10 MeV Electron Beam)

  • 이정옥;정동혁;문성록;강정구;김승곤
    • 한국의학물리학회지:의학물리
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    • 제10권1호
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    • pp.55-62
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    • 1999
  • 방사선치료에 이용되는 X-선의 특성을 고찰하기 위하여, 몬테칼로 방법을 이용하여 텅스텐 표적에 입사한 6, 10, 15 MeV 의 전자선에 의해 발생되는 X-선의 에너지분포와 평균에너지를 계산하였다. 빔의 반경의 함수로서 계산된 광자의 평균에너지는 6, 10, 15 MV에 대하여 각각, 1.4-1.6, 2.1-2.5, 2.8-3.3 MeV 범위로서 반경에 크게 의존하지 않고 거의 일정하였다. 표적과의 수직거리 100 cm에서 구해진 6, 10, 15 MV X-선의 에너지분포를 이용하여, 몬테칼로 계산으로 깊이선량율을 계산하였다. 이 중 10 MV에 대한 것을 측정값과 비교하였다. 계산된 10 MV X-선의 깊이선량율은 표면영역을 제외하고 깊이의 증가에 따라 측정값보다 낮게 나타났다. 그 이유는 실제 X-선의 에너지분포에는 편평화여과기에 의한 빔경화효과가 포함되어 있는 반면, 본 연구에서 수행한 몬테칼로 계산결과에는 이 효과가 포함되어 있지 않기 때문으로 생각된다.

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A Novel Recombinant BCG Vaccine Encoding Eimeria tenella Rhomboid and Chicken IL-2 Induces Protective Immunity Against Coccidiosis

  • Wang, Qiuyue;Chen, Lifeng;Li, Jianhua;Zheng, Jun;Cai, Ning;Gong, Pengtao;Li, Shuhong;Li, He;Zhang, Xichen
    • Parasites, Hosts and Diseases
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    • 제52권3호
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    • pp.251-256
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    • 2014
  • A novel recombinant Bacille Calmette-Guerin (rBCG) vaccine co-expressed Eimeria tenella rhomboid and cytokine chicken IL-2 (chIL-2) was constructed, and its efficacy against E. tenella challenge was observed. The rhomboid gene of E. tenella and chIL-2 gene were subcloned into integrative expression vector pMV361, producing vaccines rBCG pMV361-rho and pMV361-rho-IL2. Animal experiment via intranasal and subcutaneous route in chickens was carried out to evaluate the immune efficacy of the vaccines. The results indicated that these rBCG vaccines could obviously alleviate cacal lesions and oocyst output. Intranasal immunization with pMV361-rho and pMV361-rho-IL2 elicited better protective immunity against E. tenella than subcutaneous immunization. Splenocytes from chickens immunized with either rBCG pMV361-rho and pMV361-rho-IL2 had increased $CD4^+$ and $CD8^+$ cell production. Our data indicate recombinant BCG is able to impart partial protection against E. tenella challenge and co-expression of cytokine with antigen was an effective strategy to improve vaccine immunity.

Use of Gelatin Particle Agglutination Test for the Detection of Cymbidium mosaic virus in Cattleya Plants

  • Han, Jung-Heon;Jeong, Hyoo-Won;La, Yong-Joon
    • The Plant Pathology Journal
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    • 제17권6호
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    • pp.325-328
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    • 2001
  • Gelatin particle agglutination test (GPAT) was used to detect Cymbidum mosaic virus (CymMV) in Cattleya plants. Gelatin particles were coated with purified anti-CymMV immunoglobulin of 25-100 $\mu\textrm{g}$/ml and were subjected to several different concentrations of purified CyMfV as well as varying dilutions of orchid leaf extracts. The GPAT detected purified CymMV up to a minimum concentration of 10 $\mu\textrm{g}$/ml. CymMV was detected from crude sap extract of infected Cattleya leaves and roots up to 1:51,200 and 1:25,600 dilutions, respectively. However, the optimum range of leaf and root sap dilutions was between 50-100. Non-specific reactions were not encountered from any of the healthy orchid plants tested. The entire GPAT process was completed within 2-3 hours. This test was found to be very useful for the detection of CymMV in orchids because it is sensitive, economical, and easy to perform.

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Resistance of SOD2-transgenic petunia line to oxidative stress

  • Lee, Su-Young;Han, Bong-Hee;Kim, Yeong-Tae;Kim, Jin-Seog
    • Journal of Plant Biotechnology
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    • 제37권4호
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    • pp.562-566
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    • 2010
  • SOD2-transgenic $T_3$ petunia line (A2-36-2-1-1-35) was treated with different levels of methyl viologen (MV) to determine its resistance to oxidative stress. Four (4) levels of MV (0, 100, 200, and $400\;{\mu}M$) were applied. The SOD2-transgenic $T_3$ petunia line exhibited a very significant oxidative stress resistance at the highest MV concentration ($400\;{\mu}M$) treatment compared to non-transgenic plant. RNA and protein expression of SOD2 transgene and higher parenchyma cell density in the transgenic petunias exhibiting resistance to oxidative stress proves its contribution to the expression of its resistance to oxidative stress.

Ultradense 2-to-4 decoder in quantum-dot cellular automata technology based on MV32 gate

  • Abbasizadeh, Akram;Mosleh, Mohammad
    • ETRI Journal
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    • 제42권6호
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    • pp.912-921
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    • 2020
  • Quantum-dot cellular automata (QCA) is an alternative complementary metal-oxide-semiconductor (CMOS) technology that is used to implement high-speed logical circuits at the atomic or molecular scale. In this study, an optimal 2-to-4 decoder in QCA is presented. The proposed QCA decoder is designed using a new formulation based on the MV32 gate. Notably, the MV32 gate has three inputs and two outputs, which is equivalent two 3-input majority gates, and operates based on cellular interactions. A multilayer design is suggested for the proposed decoder. Subsequently, a new and efficient 3-to-8 QCA decoder architecture is presented using the proposed 2-to-4 QCA decoder. The simulation results of the QCADesigner 2.0.3 software show that the proposed decoders perform well. Comparisons show that the proposed 2-to-4 QCA decoder is superior to the previously proposed ones in terms of cell count, occupied area, and delay.