• Proceedings of the Korean Society for Applied Microbiology Conference
• /
• 2005.06a
• /
• pp.54-62
• /
• 2005

While genomics (the set of experimental and computational tools that allows the blueprints of life to be read) opens the doors to a more rational approach to the design and use of living cells to bring about desirable chemical transformations, genomics is, by itself, insufficient. We need tools that allow us to relate genomic and molecular information to cellular physiology and then to the response of a population of cells. We propose the development of hybrid computer cellular models. In such models genomics and chemical detail for a cellular subsystem (e.g. pathogenesis) is embedded in a coarse-grain cell model. Such a construct allows the quantitative and explicit linkage of genomic detail to cell physiology to the extracellular environment. To illustrate the principles involved we are constructing a model for a minimal cell. A minimal cell is a bacterial cell with the fewest number of genes necessary to sustain life as a free living microbe.

• Journal of Distribution Science
• /
• v.15 no.2
• /
• pp.15-20
• /
• 2017

Purpose - This paper aims to suggest a delivery constrained internet shopping optimization problem (DISOP) which must be solved for online recommendation system to provide a customized service considering cost and delivery conditions at the same time. Research design, data, and methodology - To solve a (DISOP), we propose a multi-objective formulation and a solution approach. By using a commercial optimization software (LINDO), a (DISOP) can be solved iteratively and a pareto optimal set can be calculated for real-sized problem. Results - We propose a new research problem which is different with internet shopping optimization problem since our problem considers not only the purchasing cost but also delivery conditions at the same time. Furthermore, we suggest a multi-objective mathematical formulation for our research problem and provide a solution approach to get a pareto optimal set by using numerical example. Conclusions - This paper proposes a multi-objective optimization problem to solve internet shopping optimization problem with delivery constraint and a solution approach to get a pareto optimal set. The results of research will contribute to develop a customized comparison and recommendation system to help more easy and smart online shopping service.

• Journal of Korean Library and Information Science Society
• /
• v.3
• /
• pp.79-88
• /
• 1976

In Ecorea Lrynasty, the authority all officers a compulsary obligatic.~ to learn the Nyo-I~.'z~\ulcorneruzngd er the custody of a super1 iscr o; Letters wino -1 a\ulcorner the ~ejponsible officer to train ci~ril senants. The Nyo-Kjli ilg was possible to interpret the pious love of ci I illans to the~re lders as a mutual ethics between the parental ber~ec;~lc nce and the filial piety of inferiors which n-as far superior to the traditional cthic; that was laid on an firm obligation of inieri~rs to tEei:- elders. The filial piety as a lovc for elders mean2 a mutual harrn~n:a~n d show\ulcorner a berieiolent conduct as an influence of a political morality. Thc heaer-o!erLt conduct was developed as a political morality of Confucius originated from the filial piety of Confucius based on a moral policj . Such a kenerolent conduct is to become a main spring to effect a mutual tie betn-een the king and his people as a national system of the Confucian theory. In i*

• Journal of Arbitration Studies
• /
• v.12 no.1
• /
• pp.171-205
• /
• 2002

ADR (Alternative Dispute Resolution) is a system to settle disputes without having to pursue a judgment through the courts; it provides an alternative to conventional judicial proceedings. As such, ADR is available to resolve a wide range of disputes, ranging from minor disagreements between neighbors to contracts involving millions of dollars. One can say there has been “efficient resolution of a dispute” only when it has been settled rapidly and finally to the satisfaction of all parties concerned, inexpensively and in a transparent manner. In this respect, ADR may well be regarded as the most efficient method to resolve disputes. In order to establish and disseminate ADR as a practical dispute-settlement procedure, first, governmental financial support is necessary, rather than having to depend upon fees collected from the disputing parties. At the same time, various inducement policies also are required. The most important factor is to make people aware of the fact that ADR is a low-cost, speedy system and more practical compared with other procedures. Second, cooperation from legal circles, lawyers in particular, is absolutely necessary. If disputes become serious, the general public normally seeks out lawyers for advice. Third, disputing parties have to be convinced of the benefits of ADR, secure in the knowledge that ADR will provide them not only with economic benefit but also a satisfactory result. Diverse ADR procedures should be developed and implemented to facilitate participation in a comfortable atmosphere with a mutually friendly relationship. The most important factor in achieving the wider use of ADR, which is attracting more attention of late, is the expectation that it will bring a satisfactory resolution to the related parties in dispute. The trend of seeking a new dispute-settlement method also reflects the changing sense of values in society today. Therefore, one specific method is not suitable for all kinds of disputes. A proper system should offer different approaches according to the pattern and type of dispute and the parties concerned. In selecting a dispute-resolution system, several factors have to be considered - the relationship between the parties, their financial situations, the necessity of maintaining confidentiality, urgency for settlement, etc. In the light of all these, it is desirable for the disputing parties to select the most appropriate of the available systems, not blindly turning to the courts, if and when a dispute arises.

• Journal of Arbitration Studies
• /
• v.18 no.1
• /
• pp.71-96
• /
• 2008

Arbitration is fundamentally a matter of contract, whereby contractual parties may only be required to submit a dispute to arbitration pursuant to their formal agreement. However, there are several important exceptions to this rule that have developed under common law notions of implied consent. These doctrines may serve either to benefit or to harm a nonsignatory to an arbitral agreement because either (1) the nonsignatory may compel a signatory to the agreement to arbitrate a dispute or (2) the nonsignatory may be compelled to arbitrate a dispute despite never having signed an arbitration agreement. The Court has a long-standing domestic policy of favoring arbitration, and these doctrines reflect that policy. 1. incorporation by reference An arbitration clause may apply to a party who is a nonsignatory to one agreement containing an arbitration clause but who is a signatory to a second agreement that incorporates the terms of the first agreement. 2. assumption An arbitration clause may apply to a nonsignatory who has impliedly agreed to arbitrate. Under this theory, the nonsignatory's conduct is a determinative factor. For example, a nonsignatory who voluntarily begins arbitrating the merits of a dispute before an arbitral tribunal may be bound by the arbitrator's ruling on that dispute even though the nonsignatory was not initially required to arbitrate the dispute. 3. agency A nonsignatory to an arbitration agreement may be bound to arbitrate a dispute stemming from that agreement under the traditional laws of agency. A principal may also be bound to arbitrate a claim based on an agreement containing an arbitration clause signed by the agent. The agent, however, does not generally become individually bound by executing such an agreement on behalf of a disclosed principal unless there is clear evidence that the agent intended to be bound. 4. veil piercing/alter ego In the corporate context, a nonsignatory corporation to an arbitration agreement may be bound by that agreement if the agreement is signed by its parent, subsidiary, or affiliate. 5. estoppel The doctrine of equitable estoppel is usually applied by nonsignatory defendants who wish to compel signatory plaintiffs to arbitrate a dispute. This will generally be permitted when (1) the signatory must rely on the terms of the contract in support of its claims against the nonsignatory, or (2) the signatory alleges that it and the nonsignatory engaged in interdependent misconduct that is intertwined with the obligations imposed by the contract. Therefore, this article analyzed these doctrines centering around case-law in America.

• Clinical and Experimental Reproductive Medicine
• /
• v.32 no.4
• /
• pp.337-346
• /
• 2005

Objective: The oligosaccharide moieties of glycoproteins and proteoglycans have a vital function in blastocyst differentiation. Concanavalin (ConA), a lectin, is known to bind on the preimplantation embryos, especially on blastocyst. In this study, we investigated whether ConA can modulate the trophoblast development and about the regulating mediator. Also, we investigated whether expansion is enough for hatching procession of the mouse blastocyst. Method: Embryos were collected at 72 h post hCG injection and chemicals were treated after 24 h (96 hr post hCG injection). ConA or calcium ionophore A23187 were exposed to blastocyst and than analysis the developmental process for 48 hr. Intracellular free-$Ca^{2+}$ concentration in trophectoderm was measured with confocal laser microscope after exposing to ConA or calcium ionophore A23187. ConA-pretreated blastocyst exposed to the calcium ionophore A23187 and then analyzed the developmental process. Otherwise ouabain was treated to the blastocyst to block the $Na^+/K^+$-ATPase activity. Results: In contrast to the control blastocyst, the ConA-exposed blastocysts developed beyond the expansion stage with significantly high rate (90.4%) at 12 h post administration. ConA induced an increase the intracellular $Ca^{2+}$ concentration in trophectoderm. Calcium ionophore A23187 also stimulated expansion of blastocyst. Most of the control blastocysts developed to the hatching stage at 144 h post hCG injection. However, strongly 65% of the ConA-exposed embryos were arrested at expanded stage at same time point. The developmental progression rates to hatching stage of both ConA- and calcium ionophore A23187-expose blastocysts were significantly lower than that of the control. However ConA-pretreated embryos developed to the hatching stage like control embryos. Ouabain showed a tendency to delayed the progress to expansion stage but did not inhibit the development to the hatching stage. Conclusion: ConA-mediated expansion is the result of the increase of intracellular free-calcium in blastocyst stage embryo. It is suspected that expansion of the blasocyst is a essential indirect factor in hatching and the calcium may triggering the cellular mechanisms for the both expansion and hatching progression.

• Journal of Korean Physical Therapy Science
• /
• v.4 no.1
• /
• pp.315-327
• /
• 1997

The purpose of this thesis is to investigate the application of a medical cure with a mixture of the merit of a hydrotherapy, as a kind of a physical therapy, and the remedy efficacy of mugwort, which uses in a chinese medical treatment in order to remove an unpleasant smell of HOT Pack and its tube to use in hospital. The usability of mugwort and the degree of its preference was obtained through question naires sent to 120 students including 50 students of the department of physical therapy. And the feeling, at the moment a HOT Pack Tube was opened, was investigated through 74-physical therapists. This research is to investigate the effect of the remedy to add a mugwort-pack in a HOT Pack tube using already in hospital. The results of this study are as following : The efficacy of a mugwort-pack to get rid of an unpleasant smell got better than that of a HOT Pack and its tube. As most of physical therapy laboratory lies to a basement of a hospital, the efficacy to remove a particular offensive smell of a basement got better than that of a HOT Pack using in a common hospital. Also, the degree of patients' preference on a HOT Pack to add with mugwort got to be higher and increased gradually. I can't see the definite difference of a medical remedy, but, I suppose that the visible feeling was of much help for the effect of patients's remedy.

• Proceedings of the IEEK Conference
• /
• 2003.07c
• /
• pp.2649-2652
• /
• 2003

In this Paper, an Audio-Visual Teaching aid (AVTA) for use in a classroom and with Internet is presented. A system, which was designed and tested, consists of a wireless Microphone system, Text to Speech conversion Software, Noise filtering circuit and a Computer. An IBM compatible PC with sound card and Network Interface card and a Web browser and a voice and text messenger service were used to provide slightly delayed text and also voice over the internet for remote teaming, while providing scrolling text from a real time lecture in a classroom. The motivation for design of this system, was to aid Korean students who may have difficulty in listening comprehension while have, fairly good reading ability of text. This application of this system is twofold. On one hand it will help the students in a class to view and listen to a lecture, and on the other hand, it will serve as a vehicle for remote access (audio and text) for a classroom lecture. The project provides a simple and low cost solution to remote learning and also allows a student to have access to classroom in emergency situations when the student, can not attend a class. In addition, such system allows the student in capturing a teacher's lecture in audio and text form, without the need to be present in class or having to take many notes. This system will therefore help students in many ways.

• Journal of Environmental Impact Assessment
• /
• v.16 no.1
• /
• pp.79-87
• /
• 2007

The performance of a stream water quality analysis model depends upon many factors attributed to the geological characteristics of a watershed as well as the distribution behaviors of pollutant itself on a surface of watershed. Because the model run has to import the pollution load from the watershed as a boundary condition along an interface between a stream water body and a watershed, it has been used to introduce a pollution delivery coefficient to behalf of the boundary condition of load importation. Although a nonlinear regression model (NRM) was developed to cope with the limitation of a conventional empirical way, this an up-to-date study has also a limitation that it can't be applied where the pollution load washed off (assumed at a source) is less than that delivered (observed) in a stream. The objective of this study is to identify what causes the limitation of NRM and to suggest how we can purify the process to evaluate a pollution delivery coefficient using many field observed cases. As a major result, it was found what causes the pollution load delivered to becomes bigger than that assumed at the source. In addition, the pollution load discharged to a stream water body from a specific watershed was calculated more accurately.

• Journal of Information Technology Applications and Management
• /
• v.11 no.2
• /
• pp.29-43
• /
• 2004

As the development of an information technique, gradually, mobile device is going to be miniaturized and operates at high speed. By such the requirements, the devices using a flash memory as a storage media are increasing. The flash memory consumes low power, is a small size, and has a fast access time like the main memory. But the flash memory must erase for recording and the erase cycle is limited. JFFS is a representative filesystem which reflects the characteristics of the flash memory. JFFS to be consisted of LSF structure, writes new data to the flash memory in sequential, which is not related to a file size. Mounting a filesystem or an error recovery is achieved through the sequential approach. Therefore, the mounting delay time is happened according to the file system size. This paper proposes a MJFFS to use a multi-checkpoint information to manage a mass flash file system efficiently. A MJFFS, which improves JFFS, divides a flash memory into the block for suitable to the block device, and stores file information of a checkpoint structure at fixed interval. Therefore mounting and error recovery processing reduce efficiently a number of filesystem access by collecting a smaller checkpoint information than capacity of actual files. A MJFFS will be suitable to a mobile device owing to accomplish fast mounting and error recovery using advantage of log foundation filesystem and overcoming defect of JFFS.