• Korean Journal of Head & Neck Oncology
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• v.24 no.2
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• pp.179-183
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• 2008

Objective：To evaluate efficacy and postoperative morbidity in tonsillectomy using the harmonic scalpel vs conventional electrocautery. Materials and Methods：1) We compared intra-operative bleeding and operation time and analyzed the degree of pain, oral feeding and the ability to return to normal activities from the questionnaire. 2) Animal study：Using rats, we made each linear wound with harmonic scalpel or electrocautery, then compare the width of thermal injury area with trichrome stain. Result：Harmonic scalpel tonsillectomy had significant advantages over electrocautery tonsillectomy in terms of post operative pain, oral diet tolerance and the time of return to normal life. In addition, it increased patients’ overall satisfaction with the surgery. In animal study, it was found that the thermal injury was less severe in the wound caused by harmonic scalpel than by electrocautery. Conclusion：Harmonic scalpel tonsillectomy decreases the thermal injury of the adjacent tissue, thus it has advantages over electrocautery in post tonsillectomy morbidity.

• Investigative Magnetic Resonance Imaging
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• v.22 no.1
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• pp.37-49
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• 2018

Purpose: The effect of global inhomogeneity on quantitative susceptibility mapping (QSM) was investigated. A technique referred to as Simultaneous Unwrapping Phase with Error Recovery from inhomogeneity (SUPER) is suggested as a preprocessing to QSM to remove global field inhomogeneity-induced phase by polynomial fitting. Materials and Methods: The effect of global inhomogeneity on QSM was investigated by numerical simulations. Three types of global inhomogeneity were added to the tissue susceptibility phase, and the root mean square error (RMSE) in the susceptibility map was evaluated. In-vivo QSM imaging with volunteers was carried out for 3.0T and 7.0T MRI systems to demonstrate the efficacy of the proposed method. Results: The SUPER technique removed harmonic and non-harmonic global phases. Previously only the harmonic phase was removed by the background phase removal method. The global phase contained a non-harmonic phase due to various experimental and physiological causes, which degraded a susceptibility map. The RMSE in the susceptibility map increased under the influence of global inhomogeneity; while the error was consistent, irrespective of the global inhomogeneity, if the inhomogeneity was corrected by the SUPER technique. In-vivo QSM imaging with volunteers at 3.0T and 7.0T MRI systems showed better definition in small vascular structures and reduced fluctuation and non-uniformity in the frontal lobes, where field inhomogeneity was more severe. Conclusion: Correcting global inhomogeneity using the SUPER technique is an effective way to obtain an accurate susceptibility map on QSM method. Since the susceptibility variations are small quantities in the brain tissue, correction of the inhomogeneity is an essential element for obtaining an accurate QSM.

• Journal of Biomedical Engineering Research
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• v.24 no.3
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• pp.141-149
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• 2003

This paper proposes a method of measuring and imaging the stiffness of human soft tissue to diagnose cancers or tumors which have been difficult to detect in ultrasound B-mode imaging systems. To measure the soft tissue stiffness, sinusoidal vibrations are applied to it, and the magnitude of its mechanical vibration is determined by estimating the temporal variation of speckle pattern brightness in ultrasound B-mode images. It is verified by simulation and experiment that the proposed method can estimate the relative tissue stiffness from B-mode images with a relatively small amount of computation.

• The Journal of the Korean dental association
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• v.48 no.9
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• pp.670-679
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• 2010

Esthetic demands for dental treatment are increasing every day. The interdisciplinary relationship of the restorative treatment, periodontal therapy and other treatments such as endodontics, orthodontics and so on is more emphasized nowadays to reconstruct the hard and soft tissue foundation for the esthetic restorative treatment. This article will focus on the periodontal plastic surgery for esthetic restorative treatment. These followings will be discussed. 1. Understand the relationship between teeth and gingival scaffold for esthetics 2. Discuss the classification and treatment of gummy smile 3. Recognize the gingival margin irregularities by gingival recession and how to achieve the harmonic soft tissue margins 4. describe the hard and soft tissue augmentation for ridge augmentation.

• Journal of the Korean Institute of Telematics and Electronics
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• v.27 no.12
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• pp.1916-1924
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• 1990

In this paper attenuation effect on the measurement and the tomography of nonlinear parameter is discussed. We perform computer simulation with the method using harmonic components and the method using secondary wave components, and then estimate attenuation effect through the results and compare two measurement techniques. According to simulation result the attenuation effect is more intensive as large n and \ulcorner, and the degree of the attenuation effect is represented as error functions. In the aspect of measuremnet techniques, the method using secondary wave components is more insensitive to attenuation effect than the method using harmonic compnents. We obtain the same result in the nonlinear tomography, and show that the attenuation compensive filter is required because the whole tomogram is affected by frequency dependent attenuation(or nonlinear attenuation)

• Journal of the Korean Society for Nondestructive Testing
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• v.36 no.2
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• pp.112-120
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• 2016

The nonlinearity parameter is frequently measured as a sensitive indicator in damaged material characterization or tissue harmonic imaging. Several previous studies have employed the plane wave solution, and ignored the effects of beam diffraction when measuring the non-linearity parameter ${\beta}$. This paper presents a multi-Gaussian beam approach to explicitly derive diffraction corrections for fundamental and second harmonics under quasilinear and paraxial approximation. Their effects on the nonlinearity parameter estimation demonstrate complicated dependence of ${\beta}$ on the transmitter-receiver geometries, frequency, and propagation distance. The diffraction effects on the non-linearity parameter estimation are important even in the nearfield region. Experiments are performed to show that improved ${\beta}$ values can be obtained by considering the diffraction effects.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.18 no.2
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• pp.77-105
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• 2014

Medical imaging techniques have evolved to expand our ability to visualize new contrast information of electrical, optical, and mechanical properties of tissues in the human body using noninvasive measurement methods. In particular, electrical tissue property imaging techniques have received considerable attention for the last few decades since electrical properties of biological tissues and organs change with their physiological functions and pathological states. We can express the electrical tissue properties as the frequency-dependent admittivity, which can be measured in a macroscopic scale by assessing the relation between the time-harmonic electric field and current density. The main issue is to reconstruct spectroscopic admittivity images from 10 Hz to 1 MHz, for example, with reasonably high spatial and temporal resolutions. It requires a solution of a nonlinear inverse problem involving Maxwell's equations. To solve the inverse problem with practical significance, we need deep knowledge on its mathematical formulation of underlying physical phenomena, implementation of image reconstruction algorithms, and practical limitations associated with the measurement sensitivity, specificity, noise, and data acquisition time. This paper discusses a number of issues in electrical tissue property imaging modalities and their future directions.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.24 no.1
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• pp.13-24
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• 2015

With the development of treatment of hard and soft tissue around the implants, the implant restoration is increasingly used in the maxillary anterior region which is very important aesthetically. However, the aesthetic reconstruction of the maxillary anterior region is still challenged. Three following conditions should be fully satisfied for aesthetic prosthesis restoration; reconstruction of hard tissue, soft tissue and harmonic prosthesis. In this case report, hard and soft tissue augmentations were performed at atrophied maxillary incisor. Additionally, customized impression coping and provisional restoration were used to make the final restoration.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.25 no.1
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• pp.35-49
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• 2016

With the increasing demand for aesthetic implant dentistry, the importance of implant restoration is emphasized not only in the functional aspect but also in the aesthetic aspect. The aesthetic restoration of dental implants in the anterior maxilla is a challenge for clinicians because it requires proper harmony in three following conditions; reconstruction of hard tissue, soft tissue, and aesthetic prosthesis. The soft tissue aesthetics are dependent upon the condition of the supporting hard tissue because the osseous structure provides a framework for the development of a healthy and aesthetic soft tissue interface. Therefore, the augmentation of hard tissue is a first step and especially, optimal 3-dimensional position of implant is the most important factor in aesthetic implant restoration. The management of soft tissue is a second step, and the final step is a restoration of harmonic prosthesis using provisional restoration with proper emergence profile. This clinical report describes the procedure of bone augmentation in labial dehiscence defect, Vascularized Interpositional Periosteal-Connective Tissue (VIP-CT) flap for aesthetic anterior soft tissue, and the importance of provisional restoration and impression taking stage with customized impression coping.

• Proceedings of the KOSOMBE Conference
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• v.1989 no.05
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• pp.27-28
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• 1989

In conventional line scan angiography, flow signal has been enhanced by the time_of_flight effect while the signal from stationary tissues has been suppressed by the saturation rf pulse followed by spoiling gradients. Due to the inhomogeneous rf field and the tissue dependent T1 relaxation time, however, stationary tissues can not be suppressed completely or uniformly, and the remnant stationary signal deteriorates the resultant angiogram. Here, the complete cancellation of stationary tissues is made possible by the spectral analysis of a series of repetitive line images of the same slice. The Fourier transformation of a set of line images results in the spectrum images, where stationary tissues are collected into the dc component while arteries are included in harmonic components because of the variation of the flow velocity and the resultant flow signal in arteries according to the cardiac cycle. The summation of harmonic components excluding the dc component results in the angiogram of arteries with the complete cancellation of stationary tissues.