A Study on the Stiffness Estimation in Soft Tissue Using Speckle Brightness Variance Tracking

초음파 의료영상에서 스페클의 시간적 밝기 변화를 이용한 연조직의 stiffness를 추정하는 방법에 대한 연구

  • 안동기 (대진대학교 전자 및 통신공학과) ;
  • 박정만 (대진대학교 물리학과) ;
  • 권성재 (대진대학교 전자 및 통신공학과) ;
  • 정목근 (대진대학교 전자 및 통신공학과)
  • Published : 2003.06.01

Abstract

This paper proposes a method of measuring and imaging the stiffness of human soft tissue to diagnose cancers or tumors which have been difficult to detect in ultrasound B-mode imaging systems. To measure the soft tissue stiffness, sinusoidal vibrations are applied to it, and the magnitude of its mechanical vibration is determined by estimating the temporal variation of speckle pattern brightness in ultrasound B-mode images. It is verified by simulation and experiment that the proposed method can estimate the relative tissue stiffness from B-mode images with a relatively small amount of computation.

본 논문에서는 초음파 의용 영상시스템의 B-모드 영상으로 잘 관찰되지 않는 암이나 종양을 진단하기 위하여 인체 연조직의 탄성계수를 측정하여 영상화하는 방법을 제안하였다. 연조직의 단단함을 측정하기 위하여 조직에 정현파 진동을 인가하고 연조직의 기계적인 진동의 크기를 초음파 영상의 스페클 밝기의 시간적 변화를 추정하여 구하였다. 제안한 방법은 B-모드 영상에서 비교적 적은 계산량으로 쉽게 조직의 단단함을 추정할 수 있음을 시뮬레이션과 실험으로 검증하였다

Keywords

References

  1. IEEE Trans. Ultrason. Ferroelect Freq. v.42 no.5 Theoretical bounds on strain estimation in elastography I.Cespedes;M.Insana;J.Ophir
  2. Ultrason. Imaging v.13 Elastography: A Quantitative method for imaging the elasicity of biological tissues J.Ophir;I.Cespedes;H.Ponnekanti;Y.Yazdi;X.Li
  3. Performance optimization in elastography: Multicompression with temporal stretching v.18 T.Varghese;J.Ophir
  4. Theoretical analysis and verification of ultrasound displacement and strain imaging v.41 no.3 A.R.Skovoroda;S.Y.Emilianov;M.A.Lubinski;A.P.Sarvazyan;M.O'Donnell
  5. IEEE Trans. Ultrason. Ferroelect. Freq. v.46 no.1 Speckle tracking methods for ultrasonic elasticity imaging using short-time correlation M.A.Lubinski;S.Y.Emilianov;M.O'Donnell
  6. Int. J. Imaging Syst. Tech. v.8 Theory and application of sonoelasticity imaging L.Gao;K.J.Parker;S.K.Alam;D.Rubens;R.M.Lerner
  7. J. of Acoustic Soc. of Amer. v.97 no.6 Sonoelasticity Imaging: Theory and Experimental Verification L.Gao;K.J.Parker;S.K.Alam;R.M.Lerner
  8. J of KOSOMBE v.18 no.4 In vivo Doppler based measurement of bending vibration velocity in liver vibrated by low frequency signal M.K.Park;Y.S.Jang
  9. IEEE UFFC Ultrasonic Symposium In vivo demonstration of acoustic radiation Force impulse Imaging in the thyroid Abdomen and Breast K.Nightingale;M.S.Soo;R.Nightingale;R.Bentley;G.Trahey
  10. Proc. IEEE Ultrason. Symp Ultrasound simulated Vibro-Acoustography J.F.Greenleaf;M.Fatemi
  11. Wave motion in elastic solids K.F.Graff
  12. J. of KOSOMBE v.5 no.1 Ultrasonic tissue characterization by digital spectrum analysis technique C.E.Kwack;B.G.Min;C.W.Lee;B.I.Choi;C.W.Kim
  13. IEEE Trans. Ultrason. Ferroelect. Freq. v.44 no.6 Phantom materials for elatography T.J.Hall;M.F.Insana;T.A.Krouskop