• Korean Journal of Ecology and Environment
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• v.39 no.4 s.118
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• pp.424-434
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• 2006

This study investigates bacteria-zooplankton grazing link and factors affecting their grazing relationship at trophically different two sites (Paldang Dam and Kyungan Stream) of Lake Paldang Ecosystem from April to December, 2005. Zooplankton were divided into two size groups; microzooplankton (MICZ) : 60-200 ${\mu}m$ and macrozooplankton (MACZ): >200 ${\mu}m$), and their grazing rates on bacteria were conducted for each size group separately. Bacterial abundance and seasonal change pattern were similar between two sites. MICZ, mostly rotifers (e.g., Brachionus, Keratella, Polyathra) were numerically dominant at both sites, while carbon biomass was highest in cladocerans. Zooplankton biomass was higher at the Kyungan Steam site compared to Paldang Dam site, and their high biomass during spring decreased as they were passing through the storm events in summer season at both sites. Zooplankton clearance rate (CR) was high in spring and autumn while low in summer at Paldang Dam site. However, zooplankton CR was high during the summer at Kyungan Stream site. Bacterial C-flux was high in spring and autumn when MACZ (esp. cladecerans) developed at a high biomass level at both sites. Overall, MACZ community CR and carbon flux (C-flux) were higher than those of MICZ, and the degree of difference between them was higher at Kyungan Stream site. Short hydraulic residence time and physical disturbance caused by summer storm event appeared to affect the zooplankton grazing on bacteria at both sites. The results of this study indicate that bacteria are potentially important carbon source of zooplankton, and that both biotic (e.g,, prey and predator taxa composition and abundance) and physical parameters appear to alter energy transfer in the planktonic food web of this river-reservoir hybrid system.

• Archives of Pharmacal Research
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• v.24 no.2
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• pp.126-135
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• 2001

Quinacrine (QU), a phospholipase-A2 (PLA-2) inhibitor has been used clinically as a chemotherapeutic adjuvant. To understand the mechanisms leading to its chemotherapeutic effect, we have investigated QU-induced apoptotic signaling pathways in human cervical squamous carcinoma HeLa cells. In this study, we found that QU induced cytochrome c-dependent apoptotic signaling. The release of pro-apoptotic cytochrome c was QU concentration- and time-dependent, and preceded activation of caspase-9 and -3. Flow cytometric FACScan analysis using fluorescence intensities of $DiOC_6$/ demonstrated that QU-induced cytochrome c release was independent of mitochondrial permeability transition (MPT), since the concentrations of QU that induced cytochrome c release did not alter mitochondrial membrane potential (${\blacktriangle}{\Psi}_m$). Moreover, kinetic analysis of caspase activities showed that cytochrome c release led to the activation of caspase-9 and downstream death effector caspase-3, Caspase-3 inhibitor (Ac-DEVD-CHO) partially blocked QU-induced apoptosis, suggesting the importance of caspase-3 in this apoptotic signaling mechanism. Supplementation with arachidonic acid (AA) sustained caspase-3 activation induced by QU. Using inhibitors against cellular arachidonate metabolism of lipooxygenase (Nordihydroxyguaiaretic Acid, NDGA) and cyclooxygenase (5,8,11,14-Eicosatetraynoic Acid, ETYA) demonstrated that QU-induced apoptotic signaling may be dependent on its role as a PLA-2 inhibitor. Interestingly, NDCA attenuated QU-induced cytochrome c release, caspase activity as well as apoptotic cell death. The blockade of cytochrome c release by NDCA was much more effective than that attained with cyclosporin A (CsA), a MPT inhibitor. ETYA was not effective in blocking cytochrome c release, except under very high concentrations. Caspase inhibitor z-VAD blocked the release of cytochrome c suggesting that this signaling event is caspase dependent, and caspase-8 activation may be upstream of the mitochondrial events. In summary, we report that QU induced cytochrome c-dependent apoptotic signaling cascade, which may be dependent on its role as a PLA-2 inhibitor. This apoptotic mechanism induced by QU may contribute to its known chemotherapeutic effects.

• Korea journal of population studies
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• v.26 no.2
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• pp.63-90
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• 2003

This study aims to discover patterns of Korean women's life course in terms of their life time sequence of family roles and economic activity. Primary factors for the change and diversity of family-work role sequence are also examined. Data used in this study is the Fourth Survey of Korean Women's Economic Activity which was conducted by Korean Institute of Women Development (KIWD) in 2002. According to the main results, five distinctive patterns of life course are to be disentangled for ever married women: First, doing simultaneously family and work roles with no maternal leave (13.7%); second, reentry into labor market after maternal leave (M type, 18.6%); third, no reentry into labor market after maternal leave (latent M type, 26.9%); fourth, first job entry after child rearing (23.5%); and finally, no work experience (17.3%). The relative composition of the respective life course has changed over marriage cohorts. M type including latent M type became a dominant life pattern among married women since marriage cohorts of 1980 and later. The share of married women who begin to work first after maternal role or have no work experience has declined with recent marriage cohorts. It is also noted that the share of women with simultaneous family and work roles has increased among marital cohorts of 1990 and later. Marriage cohort differences being controlled, life patterns significantly differ by women's educational level, existence of role model of working mother at growth, women's own and husbands' gender role attitude, and family economy. Finally, some policy concerns for gender role division of family and work are raised.

• Journal of the Korean earth science society
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• v.30 no.6
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• pp.734-743
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• 2009

In order to examine how climatological condition can influence on urban scale particulate air pollutants, single and cross spectrum analysis have been performed to daily mean concentrations of particulate matters ($PM_{10}$) in Busan together with the climatological variables over the Asian dust source regions. Single power spectrum analysis of $PM_{10}$ concentrations in Busan shows that, aside from the typical and well-known periodicities, 3-4 year of peak periodicity of power spectrum density was identified. In cross spectrum analysis, this 3-4 year periodicity is found to have a strong positive correlation with the wind speed and pressure, and negative with the temperature and relative humidity, which is rather consistent with both characteristics of air mass during the Asian dust event whose periodicities have been recorded inter-annually over the Korean urban cities. Over the Asian dust source regions, $PM_{10}$ vs. precipitation shows no significant periodicity from the time series of precipitation data, but the periodicity of EDI (Effective Drought Index) shows some interannual variabilities ranging from 2 to 4 years over the various source regions, suggesting that, rather than precipitation itself, the EDI could be more closely associated with the occurrence frequency of Asian dust and interannual variability of urban particle concentrations in Korean cities.

• Fire Science and Engineering
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• v.34 no.3
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• pp.134-140
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• 2020

Nuclear power plants (NPPs) in Korea are required to be maintained using a defense in-depth approach to prevent leakage of radioactive substances outside the plant and allow safe shutdown in the event of a fire. Periodic testing must be conducted to ensure that the fire protection facilities perform as required by the laws for various nuclear reactor types. In June 2017, for the first time in Korea, a nuclear plant, Kori Unit 1, was permanently shut down. It was prepared for decommissioning in accordance with the fire protection regulations imposed by the regulatory body. However, a standard protocol is necessary for systematically establishing the fire protection program for decommissioning of NPPs in the future. Therefore, the nuclear legal systems of countries with many operating nuclear power plants, such as the United States, Japan, Canada, and various European countries, were reviewed and guidelines for establishing a fire protection program for decommissioning NPPs was suggested; the fire protection requirements stated by Reg Guide 1.191 (Decommissioning fire protection program for NPPs during decommissioning and permanent shutdown) were used as a model. Suggestions for establishing legal regulations to optimize fire protection programs and secure basic technology for decommissioning NPPs were also made.

• Journal of Korea Water Resources Association
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• v.37 no.10
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• pp.857-868
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• 2004

Since the self-purification capacity of rivers in Korea is significantly controlled by environmental maintenance flow supplied by upstream reservoirs during drought season, it is obviously important to operate the river and reservoir systems considering not only water quantity aspect but also conservation of downstream water quality and ecosystem. In this study, an unsteady river water quality model KORIVl- WIN was developed as a tool for evaluating the impact. of reservoir operations on the downstream water quality. The model parameters were calibrated and verified using field data obtained in Geum River on September and October of 2002, respectively. Intensive data sampling was performed on November 22, 2003 to investigate the effect of a short-term flushing discharge of Daecheong Reservoir, which increased outflow from 30 $m^3$/s to 200 $m^3$/s for 6 hours, on downstream water quality. The model performance was evaluated by comparing simulated results with observed data including hydraulics, biochemical oxygen demand(BOD$_{5}$), nitrogen and phosphorus species during the flushing event. It showed very good performance in predicting the travel time of flushing flow and water quality variations of dissolved forms of nitrogen and phosphorus species, while revealed large deviations for BOD$_{5}$ possibly due to missing the effect of organic matters resuspension from river bottom sediment during the wave front passage.

• Journal of Preventive Medicine and Public Health
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• v.22 no.3 s.27
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• pp.355-367
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• 1989

This study examined the physical and mental health factors affecting the industrial accidents of 142 injured and 1,212 uninjured workers in the shipbuilding industry from 1986 to 1988. The results acquired from the Todai Health Index (THI) and from analysis of the health examination were as follows: 1. Among the personal characteristics of the workers, the educational level of injured workers was significantly lower than that of the uninjured workers. 2. Among the physical characteristics, vision and $R\ddot{o}hrer$ Index of the injured workers were lower than those of the uninjured workers, and the difference was statistically significant. On the other hand, the differences in height, weight, hearing function, hematocrit, blood pressure, urine test, and X-ray findings were not statistically significant between the injured and uninjured workers. 3. The score of the THI questionnaire on the physical and mental health of the injured workers was higher than that of the uninjured workers, and the difference was statistically significant. 4. Form the THI score, the industrial workers had complained more about mental health than physical health and there was a statistically singinficant relation with the industrial accidents. 5. The relative risk expressed in terms of the odds ratio was 2.9 for poorer vision, 2.7 for a lower educational level, 2.2 for a higher THI score and 1.6 for overdrinking. 6 Educational level, vision, and the THI score were selected as significant factors influencing industrial accidents based on a log-linear model. According to the results of this model by logistic analysis, the odds ratio of industrial accidents was 1.8 for a lower educational level, 1.7 for poorer vision, and 1.6 for a higher THI score. 7 By event history analysis with the dependent variable as the duration of work at the time of the industrial accident, educational level, age, $R\ddot{o}hrer$ Index and THI score were the statistically significant variables selected, and the hazard rate of industrial accident occurrence was 0.24 for a lower educational level, 0.92 for age, 0.99 for a lower $R\ddot{o}hrer$ Index and 2.72 for a higher THI score. As we have seen, educational level and THI score were the most significant factors affecting the hazard rate of industrial accidents. Vision, $R\ddot{o}hrer$ Index, age, and drinking behavior were also statistically significant variables influencing industrial accidents. Therefore, in order to prevent industrial accidents, it is necessary to establish a health management plan for industry which can objectively evaluate not only the physical but also the mental health of the workers. If we use this type of study as a prospective study design, we can determine the relative risk of physical and mental health factors on industrial accidents. Furthermore, it is expected that this type of study will provide workers at high risk with more precise basic data for a health managment plan for industrial accident prevention.

• The Journal of Korean Medical History
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• v.26 no.1
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• pp.41-53
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• 2013

In this paper, King Kyung-Jong's strange diseases which had been exacerbated by the Sinim-Sahwa(辛壬士禍) are researched and discussed. The subject will be described mostly based on health and medical records from "The Daily Records of Royal Secretariat of Chosun Dynasty(承政院日記)" and "The Annals of the Choson Dynasty(朝鮮王朝實錄)". Sinim-Sahwa had occurred for two years. It is thought that the beginning of it was 'a controversy on a proclamation of a crown prince, Yeon Ing Goon'. At the first year of Kyung-Jong's ruling, August 21, the No-Ron demanded a king's heir be decided as soon as possible, the king asked Yeon Ing Goon as his successor because of his 'strange diseases'. In October of the same year, the conflict between No-Ron and So-Ron parties reached its peak after a dispute about 'regency from behind the veil for the crown prince' at that time. Kyung-jong added that he had a mysterious and heavy disease and there was little hope to recover from it. Some opposing courtiers emphasized the king was in his good health and there weren't any actual diseases he suffered. But Kyung-Jong stubbornly persisted the diseases he had were so heavy that he couldn't get well readily. In detail, he announced his disease had so deeply rooted in internal organs that he could feel some kind of heat and fire arousal form his heart, then rage and resent soaring. Eventually, on 16th, the No-Ron party followed the king's demand, thus the king's health and illness condition itself was gradually getting off the subject. It seems that Kyung-jong's strange diseases was hwa-byung(火病). His symtoms are similar to the symtoms of hwa-byung. Environment he lived, was enough to cause hwa-byung. as a result, Sinim-Sahwa was the event what his hwa(火) was erupted.

• Journal of the Korean Society for Nondestructive Testing
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• v.21 no.1
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• pp.80-90
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• 2001

The aim of this study is to develop the methodology which enables to identify the mechanical properties of element such as stress intensity factor by using the AE parameters. Considering the multivariate and nonlinear properties of AE parameters such as ringdown count, rise time, energy, event duration and peak amplitude from fatigue cracks of machine element the principal component regression(PCR) and artificial neural network(ANN) models for the estimation of stress intensity factor were developed and validated. The AE parameters were found to be very significant to estimate the stress intensity factor. Since the statistical values including correlation coefficients, standard mr of calibration, standard error of prediction and bias were stable, the PCR and ANN models for stress intensity factor were very robust. The performance of ANN model for unknown data of stress intensity factor was better than that of PCR model.

• Journal of Navigation and Port Research
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• v.32 no.6
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• pp.499-503
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• 2008

As the conference result of MEPC in IMO, development of ballast water management system corresponding to newly established ballast water management standard (D2 regulation) of shipping is being made an active progress over the whole world. The ballast water management system should treat particular material of more than $10{\mu}m$ in high capacity of more than 500t per hour in the event of filtration process. Also, it is very difficult to develop a practical management system since a limited element which a narrow space of the ship should be designed in the minimal volume is assumed. Therefore, the study promoted a study on the next generation auto back wash media filter to overcome such a limited element. Also, the study performed pressure and flux measurement test followed by thickness of each filter medium for filtration by each size to grasp a relation between absorption and pressure at the time of vacuum filtration and mechanical analysis and turbidity change observation of filtered water after vacuum filtration.