• Journal of the Computational Structural Engineering Institute of Korea
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• v.25 no.2
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• pp.155-162
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• 2012

Recently, building of long span bridge is increasing and cable stayed bridges have large portion in civil projects. As the spans of bridges become longer, steel cable-stayed bridges have been constructed mainly for slim structure. But in many case, pylons are constructed by concrete for the stability of structures and the economy. Concrete is greatly influenced by the long-term behavior like creep and drying shrinkage, so analysis of stress redistribution and structural change in construction is required. In this study, as a cable stayed bridge with concrete pylon, Incheon Bridge is analyzed by nonlinear FEM analysis program RCAHEST. Through this analysis, time dependent effect of concrete pylon to whole cable stayed bridge system is studied.

• KSBB Journal
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• v.8 no.5
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• pp.424-430
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• 1993

The anti-stress effect by the treatment of vitamin C was investigated in this study. The treatment of ascorbic acid in the presence of $Cu^{2+}$ion induced strong time- and dose-dependent degradation of hitamine, and also the addition of histamine accelerated time-dependent decomposition of ascorbic acid in vitro. The treatment of ascorbic acid in $ODS^{od}/_{od}$rats, which cannot synthesize ascorbic acid, significantly decreased the urinary histamine. The protreatment of ascorbic acid, dexamethasone and promethazine inhibited the lethal effect induced by immobilization stress, but that of dimethylsulfoxide did not. The addition of ascorbic and to a culture of spleen cells of $ODS^{od}/_{od}$rats significantly increased the Con A-dependent T lymphocyte proliferation.

• Journal of the Korea Institute of Military Science and Technology
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• v.10 no.3
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• pp.16-24
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• 2007

The high-frequency analysis method of back-scattering cross section spectrum of rotating targets is established. The time history of the back-scattering cross section is calculated using a quasi-stationary approach, based on a physical optics and a physical theory of diffraction, combining an adaptive triangular beam method to consider the shadow effect. And the spectra of back-scattering cross section by the Doppler effect are analyzed applying a simple fast Fourier transform method to its time history. The numerical calculation for rotating targets, such as rotating metal plates and underwater propeller, are carried out. The time history appears to be periodic with respect to the number of wings. The backscattering cross section spectrum level and its frequency shift are dependent on the rotating speed, direction, and the shape of the targets.

• Geomechanics and Engineering
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• v.32 no.5
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• pp.495-502
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• 2023

In this study, stress relaxation tests were carried out by keeping silt type soil specimens under different strain levels. Decreases in the stress values with time data was collected to better understand the effect of the strain level on the relaxation properties of soil specimens. In addition, the stress relaxation effect on the uniaxial compressive strength (UCS) values of the specimens was investigated with a series of tests. According to the results obtained from this study, the UCS values of the silt specimens significantly vary as a result of the stress relaxation effect. The UCS values were determined to increase with an increase of relaxation strain level to a threshold value. On the other hand, the UCS values were found to be affected adversely in case of high stress levels at the initiation of the relaxation, which are close to the peak level.

• Korean Journal of Veterinary Research
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• v.30 no.4
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• pp.487-497
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• 1990

This study was carried out to observe in vitro effect of praziquantel on the tegumental changes of Heterophyopsis continua with scanning electron microscope. Metacercariae were collected from the perch, Lateolabrax japonicus, by artificial digestion technique and fed to 2-week old chickens. Adult worms were recovered from small intestine of chickens 8 days after infection. For working solutions, praziquantel was diluted with TC199 medium at concentration of 0.01, 0.1. 1 and $10{\mu}g/ml$. To each petri dish containing 10ml of solution, 5~10 worms were introduced and incubated at $37^{\circ}C$. For the scanning electron microscopy(SEM), the worms were fixed in cold 2.5% glutaraldehyde, dehydrated in a series of graded ethanol and freeze-dried. Dried specimen was mounted on stub and coated with gold and observed in an SEM. The results were as follows: 1. Severe tegumental alterations were recognized by scanning electron microscope. Bleb formation of tegument was observed in 5 minute group and most pronounced on anterior tegument of worms. The number and size of blebs increased as incubation time prolonged. 2. The surface destruction was more pronounced at ventral margin between the oral and the ventral suckers. 3. The sensory papillae were slightly affected, but destruction of tegumental spine was not recognized. 4. The effect of praziquantel on the worm was found dependent on the concentration and incubation time, however, the effect was more dependent upon the incubation time.

• Proceedings of the Optical Society of Korea Conference
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• 2006.07a
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• pp.131-132
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• 2006

• Structural Engineering and Mechanics
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• v.24 no.5
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• pp.621-639
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• 2006

Stability of a cylindrical shell subject to a uniform axial compression, which is a power function of time, is examined within the framework of small strain elasto-plasticity. The material of the shell is incompressible and the effect of the elastic unloading is considered. Initially, employing the infinitesimal elastic-plastic deformation theory, the fundamental relations and Donnell type stability equations for a cylindrical shell have been obtained. Then, employing Galerkin's method, those equations have been reduced to a time dependent differential equation with variable coefficient. Finally, for two initial conditions applying a Ritz type variational method, the critical static and dynamic axial loads, the corresponding wave numbers and dynamic factor have been found. Using those results, the effects of the variations of loading parameters and the variations of power of time in the axial load expression as well as the variations of the radius to thickness ratio on the critical parameters of the shells for two initial conditions are also elucidated. Comparing results with those in the literature validates the present analysis.

• Geomechanics and Engineering
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• v.20 no.1
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• pp.1-7
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• 2020

In structures excavated in rock mass, load progressively increases to a level and remains constant during the construction. Rocks display different elastic properties such as E_i and ʋ under different loading conditions and this requires to use the true values of elastic properties for the design of safe structures in rock. Also, rocks will undergo horizontal and vertical deformations depending on the amount of load applied. However, under constant loads, values of E_i and ʋ will vary in time and induce variations in the behavior of the rock mass. In some empirical equations in which deformation modulus of the rock mass is taken into consideration, elastic parameters of intact rock become functions in the equation. Hence, the use of time dependent elastic properties determined under constant loading will yield more reliable results than when only constant elastic properties are used. As well known, rock material will play an important role in the deformation mechanism since the discontinuities will be closed due to the load. In this study, E_i and ʋ values of intact rocks were investigated under different constant loads for certain rocks with high deformation capabilities. The results indicated significant time dependent variations in elastic properties under constant loading conditions. E_i value obtained from deformability test was found to be higher than the E_i value obtained from the constant loading test. This implies that when static values of elastic properties are used, the material is defined as more elastic than the rock material itself. In fact, E_i and ʋ values embedded in empirical equations are not static. Hence, this workattempts to emerge a new understanding in designing of safer structures in rock mass by numerical methods. The use of time-dependent values of E_i and ʋ under different constant loads will yield more accurate results in numerical modeling analysis.

• Biomedical Science Letters
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• v.10 no.4
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• pp.341-346
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• 2004

Tumor necrosis factor-α (TNF-α) or its mRNA expression are increased in acute nephrosis of various types including ischemia/reperfusion injury. This study was undertaken to determine whether pentoxifylline (PTX), an inhibitor of TNF-α production, provides a protective effect against hypoxia-induced cell injury in rabbit renal cortical slices. To induce hypoxia-induced cell injury, renal cortical slices were exposed to 100% N₂ atmosphere. Control slices were exposed to 100% O₂ atmosphere. The cell injury was estimated by measuring lactate dehydrogenase (LDH) release and p-aminohippurate (PAH) uptake. Exposure of slices to hypoxia increased the LDH release in a time-dependent manner. However, when slices were exposed to hypoxia in the presence of PTX, the LDH release was decreased. The protective effect of PTX was dose-dependent over the concentrations of 0.05∼1 mM. Hypoxia did not increase lipid peroxidation, whereas an organic hydroperoxide t-butylhydroperoxide (tBHP) resulted in a significant increase in lipid peroxidation. PTX did not affect tBHP-induced lipid peroxidation. Hypoxia decreased PAH uptake, which was significantly attenuated by PTX and glycine. tBHP-induced inhibition of PAH uptake was not altered by PTX, although it was prevented by antioxidant deferoxarnine. The PAH uptake by slices in rabbits with ischemic acute renal failure was prevented by PTX pretreatment. These results suggest that PTX may exert a protective effect against hypoxia-induced cell injury and its effect may due to inhibition of the TNF-α production, but not by its antioxidant action.

• Proceedings of the Korea Concrete Institute Conference
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• 1994.10a
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• pp.368-373
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• 1994

Recently, a large number of box girder bridges with cantilevered decks have been constructed. Especially, segmentally erected prestressed concrete box girder bridges are widely used as economic and aesthetic solutions for long span bridges. Segmental erection is a particularly attractive construction alternative in cases where continuously supported formwork is impractical or uneconomical. In segmentally erected bridges, the structural systems are changed as the construction stages are progressive and redistribution of member forces occurs due to time dependent effects of concrete and relaxation of prestressing steel. Then, in segmentally erected bridges, analysis are required at each construction states. In this study, nonlinear analysis progam of the segmentally erected prestressed concrete box girder bridges is developed in taking into account nonlinearity of material and geometry, time dependent effect of concrete and relaxation of prestressing steel.