• 생약학회지
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• 제1권3호
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• pp.93-99
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• 1970

There have been reported by several workers for the isolation and determination of the amine derivatives as Metbylephedrine Hydrochloride and Ephedrine Hydrochloride adopting neutralization method, steam distillation method, non-aqous titration method, ion-exchange resin method, titration method after acetylation, colorimetric method, gravimetric method, iodine titration method and gas chromatography. Those methods mentioned in above, can be practically applied for the sample which is not mixed one mith the other amine compounds. Presently, it has not shown on the isolative determination of the mixed sample of amine derivatives. In this paper, it is discussed on the isolative determination of Methylephedrine Hydrochloride as the tertiary amine compound and Ephedrine Hydrochloride as the secondary amine compound. According to the results of the experiment, it could be summarized as follows: 1. There is no time-variation on the color reaction of Methylephedrine Hydrochloride and Ephedrine Hydrochloride with the color reagent, bromcresolgreen. And Methylephedrine Hydrochloride and Ephedrine Hydrochloride, respectively, can be determined spectrophotometrically by means oft his color reaction. 2. For the isolation of Methylephedrine Hydrochloride and Ephedrine Hydrochloride from the mixed sample, Methylephedrine Hydrochloride can be eluted by chloroform, while Ephedrine Hydrochloride by the mixed solvent of chloroform and ethylalcohol (2:1), from the celite column adsorbed at pH6.4 followed by extraction with ether undersodium hydroxide alkali re action. 3. When the sample is mixed with quinine hydrochloride, dihydrocodeine bitartate, and noscapine, these mixed compounds can be eliminated by means of stram distillation. 4. When the sample is mixed with chlorpheniramine maleate, dextromethorphan hydrobromide and diphenhydramine hydrochloride, the mixed compounds can be eliminated by means of steam distillation and celite adsorption column chromatography, In conclusion, the isolative determination method for Methylephedrine Hydrochloride and Ephedrine Hydrochloride studied in this paper, indicates with the excellent reproducibility and accuracy.

• 한국컴퓨터정보학회논문지
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• 제25권5호
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• pp.11-18
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• 2020

본 연구는 컨베이어 시스템에서 딥러닝을 이용한 배출구 막힘 판단 기술에 대하여 제안한다. 제안 방법은 산업 현장의 CCTV에서 수집한 영상을 이용하여 배출구 막힘 판단을 위한 다양한 CNN 모델들을 학습시키고, 성능이 가장 좋은 모델을 사용하여 실제 공정에 적용하는 것을 목적으로 한다. CNN 모델로는 잘 알려진 VGGNet, ResNet, DenseNet, 그리고 NASNet을 사용하였으며, 모델 학습과 성능 테스트를 위하여 CCTV에서 수집한 18,000장의 영상을 이용하였다. 다양한 모델에 대한 실험 결과, VGGNet은 99.89%의 정확도와 29.05ms의 처리 시간으로 가장 좋은 성능을 보였으며, 이로부터 배출구 막힘 판단 문제에 VGGNet이 가장 적합함을 확인하였다.

• 한국통신학회논문지
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• 제40권1호
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• pp.165-170
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• 2015

본 논문은 3D 위치 정보를 산출하기 위한 기압고도계 및 기준국을 이용한 절대 고도 측정 정확도 향상에 관한 연구이다. GPS와 같은 위성 항법 시스템이 신뢰성이 있는 절대 고도를 제공하지 못하는 점과 기압 고도계가 변화하는 대기압의 특성상 절대 고도 정보를 제공하지 못한다는 문제점을 인식하고, 이를 개선하기 위해 새로운 기법을 제안하였다. 제안된 기법을 검증하기 위해 RTK를 활용한 기준국을 지정하고 시중에 판매하는 압력 센서 및 EVK 단말기를 활용하였으며, 실내 외에서의 사람의 이동으로 인한 고도 변화 실험과 차량을 이용한 이동 실험을 통해 검증하였다. 이 논문의 결과는 기준국을 이용하는 기존의 2D 측위 시스템을 간단히 3D 측위 시스템으로 확장할 수 있는 저가 솔루션을 제공할 수 있음을 보였다.

• 한국지능시스템학회논문지
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• 제26권6호
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• pp.464-470
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• 2016

본 논문은 개선된 얼굴검출 알고리즘과 눈의 개폐 빈도수로부터 운전자의 졸음을 판단하는 방법을 제안한다. 이를 위해 기존의 Viola-Jones 알고리즘과 얼굴의 공간적 상관관계를 이용하여 얼굴, 눈, 코, 입을 검출한다. 여기서, 얼굴의 공간적 상관관계는 7가지 특징에 기반한 DFP(Detect Face Part)에 의해 수행된다. Caltect 얼굴 데이터베이스에 실험을 한 결과, 특히 코 영역에 대한 검출률은 기존 Viola-Jones 알고리즘과 비교하여 13.78% 증가된 검출률을 보여주고 있다. 그리고, SVM(Support Vector Machine)과 PERCLOS(Percentage Closure of Eyes)을 사용해 시간에 따른 눈 개폐상태의 누적 값으로 운전자의 졸음 판단을 분석한다. 실험결과 93.28%의 운전자 졸음판단률을 얻어 제안된 방법의 유용성을 확인하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제27권10호
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• pp.1411-1416
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• 2014

Gender selection is important in livestock industries; for example, female calves are required in the dairy industry. Sex-sorted semen is commonly used for the production of calves of the desired gender. However, assessment of the sex ratio of the sorted semen is tedious and expensive. In this study, a rapid, cost effective and reliable method for determining the sex ratio was developed using a multiplex real-time polymerase chain reaction (PCR) assay. In this assay, the X and Y chromosome-specific markers, i.e., bovine proteolipid protein (PLP) gene and sex-determining region Y (SRY) were simultaneously quantified in a single tube. The multiplex real-time PCR assay was shown to have high amplification efficiencies (97% to 99%) comparable to the separated-tube simplex real-time PCR assay. The results obtained from both assays were not significantly different (p>0.05). The multiplex assay was validated using reference DNA of known X ratio (10%, 50%, and 90%) as templates. The measured %X in semen samples were the same within 95% confidence intervals as the expected values, i.e., >90% in X-sorted semen, <10% in Y-sorted semen and close to 50% in the unsorted semen. The multiplex real-time PCR assay as shown in this study can thus be used to assess purity of sex-sorted semen.

• Journal of Biosystems Engineering
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• 제40권3호
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• pp.165-177
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• 2015

Purpose: Accurate monitoring of soil strength is a key technology applicable to various precision agricultural practices. Soil strength has been traditionally measured using a cone penetrometer, which is time-consuming and expensive, making it difficult to obtain the spatial data required for precision agriculture. To improve the current, inefficient method of measuring soil strength, our objective was to develop and evaluate an in-situ system that could measure horizontal soil strength in real-time, while moving across a soil bin. Methods: Multiple cone-shape penetrometers were horizontally assembled at the front of a vertical plow blade at intervals of 5 cm. Each penetrometer was directly connected to a load cell, which measured loads of 0-2.54 kN. In order to process the digital signals from every individual transducer concurrently, a microcontroller was embedded into the measurement system. Wireless data communication was used between a data storage device and this real-time horizontal soil strength (RHSS) measurement system travelling at 0.5 m/s through an indoor experimental soil bin. The horizontal soil strength index (HSSI) measured by the developed system was compared with the cone index (CI) measured by a traditional cone penetrometer. Results: The coefficient of determination between the CI and the HSSI at depths of 5 cm and 10 cm ($r^2=0.67$ and 0.88, respectively) were relatively less than those measured below 20 cm ($r^2{\geq}0.93$). Additionally, the measured HSSIs were typically greater than the CIs for a given numbers of compactor operations. For an all-depth regression, the coefficient of determination was 0.94, with a RMSE of 0.23. Conclusions: A HSSI measurement system was evaluated in comparison with the conventional soil strength measurement system, CI. Further study is needed, in the form of field tests, on this real-time measurement and control system, which would be applied to precision agriculture.

• 한국경영과학회지
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• 제26권1호
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• pp.97-108
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• 2001

Design and evaluation of AGV-based material handling systems are very complicated due to the randomness and the large number of variables involved Vehicle travel time is a key parameter for designing and evaluating AGV systems. Although loaded travel time is relatively easy to estimate, determination of empty vehicle travel time is difficult due to the inherent randomness of material handling systems. Most previous studies assume that the empty vehicle travel time is the same as the loaded travel time or assume very specific environments. This paper presents new vehicle travel time models for AGV-based material transport systems. The research effort is focused on the estimation of empty vehicle travel time under various vehicle dispatching policies. Simulation experiments are used to verify the proposed travel time models.

• 한국항행학회논문지
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• 제11권3호
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• pp.239-251
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• 2007

본 논문은 기존 이동통신 단말기에서 Network-Assisted GPS 기반 위치측위방법의 개선에 관한 것으로서 이동통신 단말기가 전원이 켜져 있는 동안에는 항상 주기적으로 GPS 측위를 수행하도록 구현하고, 측위 된 위치 값을 단말기 내부 메모리에 저장하여 관리하게 구현함으로써 측위시간 단축 및 in-building 진입여부를 용이하게 판단할 수 있도록 구현하였으며, 이때 이동통신 단말기가 주기적 위치측위를 수행함으로써 발생하는 배터리 소모량을 최소화하기 위해 GPS 가시 환경 여부, 이동통신단말기의 이동성에 따라 GPS 측위 주기를 유연하게 조정함으로써 대기시간을 최대화 하는 방안을 제안했다. GPS 가시환경 및 음영환경을 구분하기 위하여 20초 동안 GPS 측위가 불가능하면 음영지역으로 정의 했다. 그리고, 단말기의 이동 여부에 따라 GPS 측위 주기를 조절하기 위해 5회 누적된 위치 정보를 이용한 누적 속도가 0.5 ~ 0.8m/sec 이하이면 정지상태로 정의했다. 이를 바탕으로 가시지역 및 음영지역에서 정지상태에서 GPS 측위 주기를 본 논문에서 제시한 주기로 설정한 경우 실제 단순 주기적인 GPS 위치 측위 대비 단말기 전류 소모량이 20 ~ 30% 이상 감소함을 확인했다.

• 한국경영과학회:학술대회논문집
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• 대한산업공학회/한국경영과학회 2000년도 춘계공동학술대회 논문집
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• pp.5-8
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• 2000

Vehicle travel time (empty travel time pius loaded travel time) is a key parameter for designing AGV-based material handling systems. Especially, the determination of empty vehicle travel time is difficult because of the stochastic nature of the empty vehicle locations. This paper presents a method to estimate vehicle travel times for AGV-based material transport systems. The model considers probabilistic aspects for the travel time and vehicle location under random vehicle selection rule and nearest vehicle selection rule. The estimation of empty travel time is of major effort. Simulation experiments are used to verify the proposed travel time model, and the simulation results show that the presented model provides reasonable travel time estimations.

• 한국수정란이식학회지
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• 제24권3호
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• pp.225-230
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• 2009

Sex-sorting of sperm is an assisted reproductive technology (ART) used by the livestock industry for the mass production of animals of a desired sex. The standard method for sorting sperm is the detection of DNA content differences between X and Y chromosome-bearing sperm by flow cytometry. However, this method has variable efficiency and therefore requires verification by a second method. We have developed a sex determination method based on quantitative real-time polymerase chain reaction (qPCR) of the porcine amelogenin (AMEL) gene. The AMEL gene is present on both the X and the Y chromosome, but the length and sequence of its noncoding regions differ between the X and Y chromosomes. By measuring the threshold cycle (Ct) of qPCR, we were able to calculate the relative frequency of X chromosome. Two sets of AMEL primers were used in these studies. One set (AME) targeted AMEL gene sequences present in both X and Y chromosome, but produced PCR products of different lengths for each chromosome. The other set (AXR) bound to AMEL gene sequences present on the X chromosome but absent esholthe Y-chromosome. Relative product levels were calculated by normalizing the AXR fluorescence to the AME fluorescence. The AMEL method accurately predicted the sex ratios of boar sperm, demonstrating that it has potential value as a sex determination method.