• Title/Summary/Keyword: Tic

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TIC SYMPTOM EXACERBATION ASSOCIATED WITH STREPTOCOCCAL INFECTION IN TOURETTE'S DISORDER (A군 연구균 감염이후 Antistreptolysin-O 혈중 농도 증가가 뚜렛씨 장애의 증상악화에 미치는 영향에 대한 임상 연구)

  • Joung, Yoo-Sook
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.9 no.2
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    • pp.209-217
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    • 1998
  • Object:The purpose of this study was to investigate that infection with group $A[{\beta}]$ hemolytic streptococcus may associate the mechanisms that cause or exacerbate the tic symptoms in some cases of Tourette's disorder Method:Fourteen cases with abrupt worsening of tics participated in this study:10 males,4 females. The subjects were divided into two groups composing of the group with increasing level of ASO titer and the group with normal level of ASO titer. The subjects were administered Yale Global Tic Severity Scale(YGTSS). Result:The global severity scores and overall TS impairment rating scores of YGTSS in the group with increasing level of ASO titer were more higher than in the group with normal level of ASO titer Conclusion:These results suggest that increasing level of ASO titer, resulting from group $A[{\beta}]$ hemolytic streptococcal infection has affected worsening the tic symptoms in Touette's disorder.

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Seasonal and Regional Concentrations of Chemical Composition in Rainwater in Daegu Area (대구지역의 빗물 중 화학적 성분의 계절별 및 지역별 농도분포)

  • Song, Hee-Bong;Lee, Eun-Kyeong;Jung, Dong-Sook;Kim, In-Ok;Lee, Myeong-Sug;Kwon, Byoung-Youne;Lee, Kyoung-Chool
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.5
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    • pp.522-526
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    • 2006
  • To investigate the characteristics of rainwater in Daegu area, parameters such as pH, electrical conductivity, TOC, TIC and TC were analyzed on 34 samples from January to December 2005. Results revealed that higher values were measured in winter than in summer. Furthermore samples that originated from industrial and commercial areas had higher chemical concentrations and conductivity as compared with those from residential and reference areas. Seldom acid-rain occurrence was recorded(27.2%) as compared with non-acid precipitation(72.8%) incidence. Also higher organic carbon fraction(TOC) was detected(72.5%) than inorganic form(TIC)(27.5%) in terms of component ratio with TC. During frequent rainfalls, the concentration of chemicals was decreased to a degree. Conversely, lower rate of rainfall gave out higher chemical values. Thereby the improvement of air qualify in 2005 compare with 2003 report was influenced by the environment authorities' efforts to reduce air pollutions and various factors by the depression of the region's economy.

Association of Pre- and Perinatal Risk Factors With Tourette Syndrome or Chronic Tic Disorders in a Korean School-Age Population

  • Wooseok Choi;Soon-beom Hong;Johanna Inhynag Kim;Jung Lee;Soomin Jang;Yebin D Ahn;You Bin Lim;Sumin Kim;Mee Rim Oh;Bung-Nyun Kim
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.34 no.1
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    • pp.37-44
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    • 2023
  • Objectives: Tic disorders are highly heritable; however, growing evidence suggests that environmental factors play a significant role in their pathogenesis. Studies on these factors have been inconsistent, with conflicting results. Therefore, this study aimed to examine the associations of pre- and perinatal exposure to Tourette syndrome (TS) or chronic tic disorders (CTD) in Korean school-aged children. Methods: This case-control study used data from a large prospective cohort study. The primary outcome was TS/CTD diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) criteria and Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean Version. Demographic, pre-, and perinatal information was obtained from the maternal questionnaires. Data between the TS/CTD and control groups were compared using the chi-squared or Student's t-test, as appropriate. Two-step logistic regression analyses were used to test the association between TS/CTD and pre- and perinatal risk factors. Results: We included of 223 children (78 with TS/CTD and 145 controls). Significant differences in the demographic data between the two groups were observed. The male sex ratio, mean parental age, parental final education level, and family history of tics were included as confounders. In the final adjusted multivariable model, TS/CTD was significantly associated with antiemetic exposure during pregnancy (odds ratio [OR]=16.61, 95% confidence interval [CI] 1.49-185.22, p=0.02) and medically assisted reproduction (OR=7.89, 95% CI 2.28-27.28, p=0.01). Conclusion: Antiemetic exposure and medically assisted reproduction are significantly associated with the risk of TS/CTD. These results should be replicated in future prospective and gene-by-environment studies.

A Case of Antipsychotic-Regression Syndrome in Haloperidol Treated Tourette's Syndrome (Haloperidol로 치료한 Tourette 장애에서 발생한 항정신병약물-퇴행 증후군 1례)

  • Jeong, Hee-Yeon;Cho, Hyun-Ju;Kwon, Young-Joon;Park, In-Joon;Jin, Hyuk-Hee
    • Korean Journal of Biological Psychiatry
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    • v.5 no.1
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    • pp.134-137
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    • 1998
  • Authors report a case of separation anxiety disorder, which developed as a side effect during haloperidol treatment of Tourette syndrome(TS). In this case, 14 years old boy developed attention deficit symptoms during his infancy. At 4th grade of primary school, he developed vocal tic, motor tic, and coprolalia. With 5mg/day of haloperidol treatment his symptoms of TS were subsided. During the treatment, he developed features of separation anxiety disorder, including dependence, pleading, clinging, and sadness. Symptoms of attention deficit and separation anxiety disorder were improved by 25mg/day of imipramine treatment. During haloperidol treatment of TS, careful observation may be needed whether separation anxiety disorder-like symptom develops.

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Efficient AMBA Based System-on-a-chip Core Test With IEEE 1500 Wrapper (IEEE 1500 래퍼를 이용한 효과적인 AMBA 기반 시스템-온-칩 코아 테스트)

  • Yi, Hyun-Bean;Han, Ju-Hee;Kim, Byeong-Jin;Park, Sung-Ju
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.45 no.2
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    • pp.61-68
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    • 2008
  • This paper introduces an embedded core test wrapper for AMBA based System-on-Chip(SoC) test. The proposed test wrapper is compatible with IEEE 1500 and can be controlled by ARM Test Interface Controller(TIC). We use IEEE 1500 wrapper boundary registers as temporal registers to load test results as well as test patterns and apply a modified scan test procedure. Test time is reduced by simultaneously performing primary input insertion and primary output observation as well as scan-in and scan-out.

Memory retrieval with a DNA computing (DNA 연산을 이용한 기억 인출 시뮬레이션)

  • Kim Joon-Shik;Lee Eun-Seok;Noh Yung-Kyun;Zhang Byoung-Tak
    • Proceedings of the Korean Information Science Society Conference
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    • 2006.06a
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    • pp.34-36
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    • 2006
  • 본 연구는 특정 사물을 계속 접하면서 그 사물에 대한 기억 강도가 의식적 노력 없이도 점점 강화되는 암묵적 기억 인출과정 associative memory retrieval의 DNA 연산 가능성을 논한다. 예를 들어 한 표적 단어에 대한 노출이 이를 관찰하는 시스템에게 그 단어의 기억 강도를 강화시키는 반면, 그와 유사한 다른 단어는 천천히 감소되고 나머지 가장 다른 단어는 일찍 잊혀지는 현상을 생각할 수 있다. 이들 단어들과 알파벳 철자들을 DNA 염기서열로 표현하고 simulated annealing을 통하여 결합 결과를 얻는다. Ridge regression 형태의 supervised 학습을 통하여 한 가지 표적 단어가 많이 생성되도록 DNA 조각들의 개수 분포를 변화시켜 진행한다. 실험 예로 'tic' 'tac' 'toe' 세 가지 단어를 그 아이템으로 정하여 계속 자극받는 표적 단어의 갯수가 증가함을 DNA annealing 시뮬레이션을 통하여 확인할 수 있다. 또한 'tac' 과 't' 와 'c'를 공유하는 'tic' 의 감소 점도가 't'만을 공유하는 'toe' 보다 느림을 확인할 수 있다. 위의 실험들을 통해 연합기억associative memory의 암묵적 인출과정을 분자 층위에서 표현할 수 있음을 확인 할 수 있다.

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Development of a CAE Tool for P/M Compaction Process and Its Application (금형압축성형공정 해석용 CAE 프로그램 개발 및 적용)

  • Chung Suk-Hwan;Kwon Young-Sam
    • Journal of Powder Materials
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    • v.11 no.5
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    • pp.399-411
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    • 2004
  • Crack generation during die compaction and distortion during sintering have been critical problems for the conventional pressing and sintering process. Until now, trial and error approach with engineers' industrial experiences has been only solution to protect the crack generation and distortion. However, with complexity in shape and process it is very difficult to design process conditions without CAE analysis. We developed the exclusive CAE software (PMsolver/Compaction) for die compaction process. The accuracy of PMsolver is verified by comparing the finite element simulation results with experimental results. The simplified procedures to find material properties are proposed and verified with iron based powder and tungsten carbide powder. Based on the accurate simulation result by PMsolver, the optimal process conditions are designed to get uniform density distribution in a powder compact after die compaction process by using a derivative based optimization scheme. In addition, the effect of non-uniform density distribution in a powder compact on distortion during sintering is shown in case of the fabrication of tungsten carbide insert.