Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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A Case of Antipsychotic-Regression Syndrome in Haloperidol Treated Tourette's Syndrome

Haloperidol로 치료한 Tourette 장애에서 발생한 항정신병약물-퇴행 증후군 1례

  • Jeong, Hee-Yeon (Department of Neuropsychiatry, College of Medicine, Soonchunhyang University) ;
  • Cho, Hyun-Ju (Department of Neuropsychiatry, College of Medicine, Soonchunhyang University) ;
  • Kwon, Young-Joon (Department of Neuropsychiatry, College of Medicine, Soonchunhyang University) ;
  • Park, In-Joon (Department of Neuropsychiatry, College of Medicine, Soonchunhyang University) ;
  • Jin, Hyuk-Hee (Department of Neuropsychiatry, College of Medicine, Soonchunhyang University)
  • 정희연 (순천향대학교 천안병원 신경정신과학교실) ;
  • 조현주 (순천향대학교 천안병원 신경정신과학교실) ;
  • 권영준 (순천향대학교 천안병원 신경정신과학교실) ;
  • 박인준 (순천향대학교 천안병원 신경정신과학교실) ;
  • 진혁희 (순천향대학교 구미병원 신경정신과)
  • Published : 1998.06.25
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Abstract

Authors report a case of separation anxiety disorder, which developed as a side effect during haloperidol treatment of Tourette syndrome(TS). In this case, 14 years old boy developed attention deficit symptoms during his infancy. At 4th grade of primary school, he developed vocal tic, motor tic, and coprolalia. With 5mg/day of haloperidol treatment his symptoms of TS were subsided. During the treatment, he developed features of separation anxiety disorder, including dependence, pleading, clinging, and sadness. Symptoms of attention deficit and separation anxiety disorder were improved by 25mg/day of imipramine treatment. During haloperidol treatment of TS, careful observation may be needed whether separation anxiety disorder-like symptom develops.

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