• The Korean Journal of Pain
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• v.20 no.2
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• pp.100-105
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• 2007

Background: Ginseng has been used to manage various types of pain in folk medicine. This study characterized the effect of treatment with intrathecal ginsenosides, the active components of ginseng in a postoperative pain model. Methods: Male Sprague-Dawley rats were implanted with lumbar intrathecal catheters. An incision was made in the plantar surface of the hindpaw. Withdrawal thresholds following the application of a von Frey filament to the wound site were measured. To determine the role of the opioid or GABA receptors following treatment with the ginsenosides, naloxone, bicuculline (a $GABA_A$ receptor antagonist), and saclofen (a $GABA_B$ receptor antagonist) were administered intrathecally 10 min before the delivery of the ginsenosides and the changes of the withdrawal thresholds after application of the von Frey filament were Observed. Results: Treatment with the intrathecal ginsenosides increased the withdrawal threshold in a dose dependent manner. Pre-treatment with intrathecal naloxone reversed the antinociceptive effect of the ginsenosides. However, pre-treatment with intrathecal bicuculline and saclofen failed to have an effect on the activity of the ginsenosides. Conclusions: These results suggest that ginsenosides are effective to alleviate the postoperative pain evoked by paw incision. The opioid receptor, but not GABA receptors, may be involved in the antinociceptive action of the ginsenosides at the spinal level.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.6
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• pp.4067-4076
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• 2015

This study aims to examine the trend in household catastrophic medical expenditure according to the healthcare coverage types and its associated factors based on the raw data of the Korean Health Panel over the years 2008 to 2011. Correspondence analysis was used to investigate the trend in the incidence rates of annual catastrophic medical expenditure and generalized estimating equation to examine the factors influencing the incidence of catastrophic medical expenditure. The annual mean incidence rates of household catastrophic medical expenditure were 25.1%, 15.4%, 10.1%, 5.4% and 3.2% in the threshold levels of 10%, 15%, 20%, 30%, and 40% respectively. The incidence rate of household catastrophic medical expenditure was higher when the total annual household income was lower, the education level of the householder was lower, the healthcare coverage type was National Health Insurance, the householder had disability, the age of the householder was older, the number of household members was smaller, the subjective health status of household members was lower, and the prevalence rate of the chronic disease of the household was higher(p<0.05). Therefore, a policy for vulnerable households with older or patient members of chronic diseases should be established.

• Food Science of Animal Resources
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• v.32 no.4
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• pp.396-403
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• 2012

This study was conducted in order to investigate the effect of storage temperature abuse on the freshness of refrigerated and frozen spent hen's meat. After a room temperature storage condition, two different storage temperature were followed: refrigeration and frozen storage. All parts of the spent hen's meats were thawed at 4 d intervals up to 3 times (2, 6, and 10 d) for 24 h. The level of bacteria on the different parts of the refrigerated and frozen meats was higher than 6 Log CFU/g under the following storage conditions: refrigerated - breast, 12 h; leg, 6 h; wing, 12 h at the $1^{st}$ analysis, frozen - breast, 12 h at the $2^{nd}$ analysis; leg, 24 h at the $1^{st}$ analysis; wing, 12 h at the $1^{st}$ analysis. The pH value for the leg meat was higher than breast and wing meats. In the color measurements, under the room temperature storage condition, lightness and redness values decreased but the yellowness increased in refrigerated meats (p<0.05). The K-value regarding refrigerated leg meats exceeded 60%, which is the threshold value to evaluate the degree of freshness, during the $1^{st}$ analysis (p<0.05). The VBN value of refrigerated leg meat was the highest and reached up to 96.93 mg%. Thus, studies regarding the possible decline in quality according to the change of storage temperature could be used in order to establish a basic database for the quality control of spent hen meat being traded with other countries.

• Journal of the Korea institute for structural maintenance and inspection
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• v.24 no.1
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• pp.8-15
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• 2020

In the present paper, as a way of reducing heavyweight impact sounds, in particular, among floor impact sounds which have come to the forefront as a social issue recently, a floor joist slab is proposed that is expected to bring an effect of reducing heavyweight impact sounds through a shift in the natural frequency by installing a floor joist on a flat-type slab to increase the rigidity of the floor slab, differently from the existing method that increases the thickness of floor slab, and the heavyweight impact sound characteristics depending on the floor joist height and interval are interpretively analyzed. As a result of the analysis, though a trend is shown where the sound pressure level decreases as the slab thickness of floor joist increases, and as no difference is shown when thickness is above a certain value, it is thought that there is a threshold for the effect of an increase in floor thickness on blockage of heavyweight impact sounds. Also, as an increase in floor rigidity resulting from an increase in the floor joist height and a decrease in the interval does not lead to a consistent increase in the performance of blocking heavyweight impact sounds, it is thought that a different floor joist height and interval should be applied to each type of house to expect optimum performance of blocking heavyweight impact sounds, and an increase of 100mm in the floor joist height or a decrease of about 100mm in the interval is expected to bring an effect of reducing heavyweight impact sounds by about 1dB to 2dB.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.10
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• pp.415-424
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• 2019

In this paper, a minimum rotation radius was designed and fabricated to overcome the threshold so that elderly or disabled people who have difficulty moving can move and transfer safely and conveniently in a narrow room. In the indoor environment, where the sedentary culture develops, this study aimed to provide convenience for passengers with fracture diseases, geriatric diseases, and other knee and waist diseases. First, links, seats, armrests, covers, motors, batteries, chargers, controllers, etc. were attached to the frame so that they could be moved and lifted indoors. The product design and structure were designed considering the user's environment and physical characteristics, and IoT functions were added. A driving experiment was performed to confirm the operating performance of the manufactured indoor moving and lifting wheelchair. The performance tests, such as continuous running time, turning radius, maximum actuator load, maximum lift height, sound pressure level, minimum sensing distance of the driving aid sensor, interworking of server and app programs, device compatibility, and duty cycle error rate, were performed. As a result of the test, the built-in wheelchair could achieve the performance test target of each item and operate successfully.

• Journal of Environmental Impact Assessment
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• v.28 no.5
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• pp.457-470
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• 2019

This study aims to present the characteristics of marine physics, water quality, and sediment quality around offshore wind farm near the Gochang and Buan sea areas through the analysis of monitoring data. The relationships between suspended solid and wave height as well as suspended solid and flow velocity were analyzed. We found that Correlation Coefficient values of 0.61~0.69 between wave height and suspended solid, and suspended solid concentration reaches 75 mg/L or higher when wave height of more than 1m occurred in the spring (1 month). The water quality index (WQI) was used to identify the status of the water quality in the study area. Most of the measured points were rated first grade (very good). The variation of chlorophyll-a was relatively hight compared to the other criteria, indicating that it is a major factor affecting the quality index. In the sediment column, all heavy metals were detected below the Threshold Effects Level(TEL), and ignition loss and grain size show a positive correlation.

• Journal of the Korean Society of Hazard Mitigation
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• v.11 no.2
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• pp.113-125
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• 2011

In this study, recent trends of the annual precipitation, the annual maximum precipitation of different durations and the rain days over several thresholds(i.e. 0, 10, 20, 40, 60 and 80 mm/day) according to the different local features were analyzed using daily precipitation data of 59 weather stations between 1973 and 2009. To analyze the variability according to the regional characteristics, 59 weather stations were classified by elevations, latitudes, longitudes, river basins, inland or shore(east sea, south sea, west sea) area and the level of urbanization. Results demonstrated that overall trend of variables increases except rain day. Results according to the regional characteristics showed that the increase trend becomes stronger with elevation increase. The increase trend of Han river basin is largest and that of Youngsan river basin is smallest. Also the increase trend becomes stronger with latitude increase and that of East coast is larger than that of South coast since it may be caused by the regional difference of elevation. The increase trend of urban area is larger than that of rural area. Overall trend showed that increase trend becomes stronger with elevation and latitude increase.

• Journal of Korea Water Resources Association
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• v.51 no.12
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• pp.1181-1194
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• 2018

This study suggests a novel approach of estimating stream flow discharge using the Synthetic Aperture Radar (SAR) images taken from 2015 to 2017 by European Space Agency Sentinel-1 satellite. Fifteen small to medium sized rivers in the Han River basin were selected as study area, and the SAR satellite images and flow data from water level and flow observation system operated by the Korea Institute of Hydrological Survey were used for model construction. First, we apply the histogram matching technique to 12 SAR images that have undergone various preprocessing processes for error correction to make the brightness distribution of the images the same. Then, the flow estimation model was constructed by deriving the relationship between the area of the stream water body extracted using the threshold classification method and the in-situ flow data. As a result, we could construct a power function type flow estimation model at the fourteen study areas except for one station. The minimum, the mean, and the maximum coefficient of determination ($R^2$) of the models of at fourteen study areas were 0.30, 0.80, and 0.99, respectively.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.04a
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• pp.62-62
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• 2019

Bacterial leaf blight(BLB), caused by X. oryzae pv. oryzae(Xoo), is one of the most destructive diseases of rice due to its high epidemic potential. Understanding BLB resistance at a genetic level is important to further improve the rice breeding that provides one of the best approaches to control BLB disease. In the present investigation, a collection of 192 accessions was used in the genome-wide association study (GWAS) for BLB resistance loci against four Korean races of Xoo that were represented by the prevailing BLB isolates under Xoo differential system. A total of 192 accessions of rice germplasm were selected on the basis of the bioassay using four isolated races of Xoo such as K1 and K2. The selected accessions was used to prepare 384-plex genotyping by sequencing (GBS) libraries and Illumina HiSeq 2000 pairedend read was used for GBS sequencing. GWAS was conducted using TASSEL 5.0. The TASSEL program uses a mixed linear model (MLM). The results of the bioassay using a selected set of 192 accessions showed that a large number of accessions (93.75%) were resistant to K1 race and K2 resistant germplasm proportion remained between 66.67. The genotypic data produced SNP matrix for a total of 293,379 SNPs. After imputation the missing data was removed, which exhibited 34,724 SNPs for association analysis. GWAS results showed strong signals of association at a threshold of [-log10(P-value)] more than 5 (K1 and K2) for nine of the 39 SNPs, which are plausible candidate loci of resistance genes. These SNP loci were positioned on rice chromosome 2, 9, and 11 for K1 and K2 races. The significant loci detected have also been illustrated and make the CPAS markers for NBS-LRR type disease resistance protein, SNARE domain containing protein, Histone deacetylase 19, NADP-dependent oxidoreductase, and other expressed and unknown proteins. Our results provide a better understanding of the distribution of genetic variation of BLB resistance to Korean pathogen races and breeding of resistant rice.

• Korean Journal of Remote Sensing
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• v.37 no.3
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• pp.503-514
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• 2021

Rice production with adequate level of area is important for decision making of rice supply and demand policy. It is essential to grasp rice cultivation areas in advance for estimating rice production of the year. This study was carried out to classify paddy rice cultivation in Gimje-si using sentinel-1 SAR (synthetic aperture radar) and UAV imagery in early July. Time-series Sentinel-1A and 1B images acquired from early May to early July were processed to convert into sigma naught (dB) images using SNAP (SeNtinel application platform, Version 8.0) toolbox provided by European Space Agency. Farm map and parcel map, which are spatial data of vector polygon, were used to stratify paddy field population for classifying rice paddy cultivation. To distinguish paddy rice from other crops grown in the paddy fields, we used the decision tree method using threshold levels and random forest model. Random forest model, trained by mainly rice cultivation area and rice and soybean cultivation area in UAV image area, showed the best performance as overall accuracy 89.9%, Kappa coefficient 0.774. Through this, we were able to confirm the possibility of early estimation of rice cultivation area in Gimje-si using UAV image.