• Fire Science and Engineering
• /
• v.33 no.4
• /
• pp.16-27
• /
• 2019

A burning test was conducted on the smoke and combustion gases generated from cypress wood treated with sodium silicate, 3-aminopropyltrimethoxysilane sol, 3-(2-aminoethylamino)propylmethyldimethoxysilane sol, and 3-(2-aminoethylamino) propyltrimethoxysilane sol. The silicone compound sol was applied to each of the cypress wood specimens three times with a brush. The smoke and combustion generation gas were analyzed using a cone calorimeter (ISO 5660-1) and the smoke was also evaluated by applying new smoke risk assessment method. The smoke performance index (SPI) of the cypress treated with silicone compound increased 1.66 to 8.42 times and the smoke growth index (SGI) was 11.8 to 88.2%, respectively. The smoke intensity (SI) is expected to be 1.0~50.5% lower than that of the base specimens, resulting in lower smoke and fire hazards. The third maximum carbon monoxide (CO_peak) concentration of the specimens treated with silicone compounds was 22.5~33.3% lower than that of the base specimens. On the other hand, it produced potentially fatal toxicity that was 1.48~1.72 times higher than the US Occupational Safety and Health Administration (OSHA) acceptance standard (PEL). Cypress wood itself produced a high carbon monoxide concentration, but the silicon compound played a role in reducing this level.

• The Journal of the Korea Contents Association
• /
• v.18 no.1
• /
• pp.370-380
• /
• 2018

The purpose of this study is to analyze the program according to the local characteristics of the elderly welfare center and to present the development direction of the elderly welfare center in the future. The questionnaire was administered to 344 elderly welfare centers nationwide and 304 questionnaires were used for analysis. Based on the regional characteristics of the elderly welfare center, three types were derived and analyzed. The results of this study are as follows: First, the projects which showed difference according to the regional characteristics of the elderly welfare center were the functional recovery program, counseling, emotional support, and community welfare program. Second, it was found that the elderly welfare centers had different programs according to their areas. The results showed that the elderly welfare centers had different programs, group programs, self-help groups, beauty services, employment support education, economic education, retirement preparation education, home helper service, generation integration program, mobile welfare business and regional cooperation project. Based on these results, it is suggested that the development direction of the elderly welfare center is necessary to develop the program of the elderly welfare center according to the characteristics of the region and it is necessary to guarantee autonomy so that the elderly welfare center can operate the program.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.34 no.8
• /
• pp.1143-1150
• /
• 2005

Antioxidative activities of 5 common edible seaweeds in Korea, three brown algae (seaweed fusiforme, sea mustard, sea tangle), one green algae (sea lettuce) and one red algae (laver), were examined. The antioxidative activities of ethanol extracts from these seaweeds were examined by measuring of inhibition rates against iron-induced linoleate peroxidation, DPPH (1,1-diphenyl -2-picrylhydrazyl) radical generation and MDA-BSA (malondialdehyde-bovine serum albumin) conjugation. Sea lettuce ethanol extract showed the strongest anti-oxidative activity among them, especially in inhibition against conjugation of lipid peroxide and protein. Second to sea lettuce, laver and sea tangle ethanol extracts showed high DPPH radical scavenging activity and inhibition against MDA-BSA conjugation. However, seaweed fusiforme and sea mustard ethanol extracts did not show antioxidative activities. Sea mustard contained the highest total flavonoids (11.33 mg/g dry wt) and sea lettuce contained the highest total polyphenol (8.97 mg/g dry wt) among these seaweeds. In addition, there was strong positive correlation between the antioxidative activity and total polyphenol content in these seaweeds, suggesting polyphenol compounds may contribute to antioxidative effect of seaweeds. From these data, it is suggested to consume much of seaweeds such as sea lettuce, laver and sea tangle to prevent age-related chronic diseases, and also develope neutraceutical products using polyphenol rich fraction from sea lettuce.

• Archives of Pharmacal Research
• /
• v.18 no.6
• /
• pp.449-453
• /
• 1995

The search for patinum (II)-based compounds with improved therapeutic properties was prompted to design and synthesize a new family of water-soluble, third generation cis-diamminedichlorplatinum (II) complexes linked to uracil and uridine. Six heretofore undescribed uracil and uridine-platinum (II) complexes are ; [N-(2-aminoethyl)uracil-5-carboxamide]dichloroplatinum (II)(3a), [N-2(2-aminoethyl)uracil-6-carboxmide]dichloroplatinum (II) (3b),[5-(2-aminorthyl)carbamoyl-2',3',5',-tri-O-acetyluridine] dichloroplatinum (II) (6b), [5-(2-aminoethyl)-carbamoyl]-2',3',5',-tri-O-acetyluridine] dichloroplatinum (II) (6b), [5-(2-aminoethyl)carbamoylu-ridine]dihloroplatinum (II) (7a), [6-(2-aminoethyl)carbamoyluridine]dichloroplatinum (II) (7b). These analogues were prepared from the key starting materials, 5-carboxyuracil (1a) and 6-carboxyuracil (1b) which were reacted with ethylenediamine to afford the respective N-(2-aminoethyl)uracil-5-carboxmide (2a) land N-(2-aminoethyl)uracil-6-carboxamide (2b). The cisplatin complexes 3a and 3b were obtained through the reaction of the respective 2a and 2b ficiently introduced on the .betha.-D-ribose ring via a Vorbruggen-type nucleoside coupling procedure with hexamethyldisilazane, trimethylchlorosilane and stannicchloride under anhydrous acetonitfile to yield the sterospecific .betha.-anomeric 5-carboxy-2',3',5'-tri-O-acetyluridine (4a) and 6-carboxy-2',3',5'-tri-O-acetyluridine (4b), respective 5-(2-aminoethyl)carbamoyl-2',3',5'-tri-O-acetyluridine (5a) and 6-(2-aminoethyl)carbamoyl-2',3',5'-tri-O-acetyluridine (5b). The diamino-uridines 5a and 5b were reacted with potassium tetrachloroplatinate (II) to give the novel nucleoside complexes, 6a and 6b respectively which were deacetylated into the free nucleosides, 7a and 7b by the treatment with CH/sub 3/ONa. The antitumor activities were evaluated against three cell lines (K-562, FM-3A and P-388).

• YAKHAK HOEJI
• /
• v.52 no.2
• /
• pp.137-146
• /
• 2008

Even though driving under the influence of drug (DUID) is a worldwide problem, we, Korea has no regulation system yet except for alcohol, and there are little cases reported related to DUID. In order to investigate the type of abused drugs for drivers in Korea, we tried to analyze controlled and non-controlled drugs in alcohol-positive blood samples. 275 whole bloods, which were positive for alcohol on the roadside test, were collected from the police for two months ($Nov.{\sim}Dec.$ 2006). The analytical strategy was constituted of three steps: First, alcohol in blood samples were confirmed and quantified by gas chromatography. Second, controlled drugs were screened by $Evidence_{investigator}\;^{TM}$ (Randox, U.K.) as preliminary test. It was based on immunoassay by biochip array analyzer. Nine groups of drug abuse were screened: amphetamines, methamphetamines, cannabis, cocaine, opiates, barbiturates, methadone, benzodiazepines I (oxazepam) & II (lorazepam). Finally, confirmation of these drugs was performed by GC-MS. Blood samples were extracted by solid-phase extraction by $RapidTrace^{TM}$ (Zymark, U.S.A.). After trimethylsilyl (TMS) derivatization, eluates were analyzed to GC-MS. Total 49 drugs were investigated in this study including controlled drugs, antidepressants, 1st generation antihistamines, dextromethorphan, nalbuphine, ketamine, etc. For rapid detection, we developed the automated identification system. It was made up a new software, "DrugMan", modified Chemstation data analysis menu and newly developed macro modules. A series of peak selection, identification and reporting of the results were performed automatically by this system. Concentrations of alcohol in 275 blood samples were ranged from 0.011 to 0.249% (average, 0.119%). Among 149 blood samples, just six samples (4.0%) were showed positive results to the immunoassay: one methamphetamine and five benzodiazepines group I. By GC-MS confirmation, only benzodiazepines were detected and methamphetamine was not detected from immunoassay positive blood sample. Besides these drugs, 5 chlorpheniramines, dextromethorphan, diazepam, doxylamine, ibuprofen, lidocaine and topiramate were also detected in whole bloods by GC-MS. Conclusively, the frequency of drug abuse for Korean drivers was relatively low. There was none case which illegal drug was detected. However these results were limited to alcohol positive blood samples, so it is necessary to analyze more samples including alcohol negative blood.

• Korean journal of communication and information
• /
• v.47
• /
• pp.120-147
• /
• 2009

The purpose of this paper is to promote bilateral friendly relations, the elements that hinder Hate Korea wave's(Kenkanryu) status and an analyzation of the characteristics of its causes and solutions for it. The Hate Korea wave is to be discussed in the fountain Hate Korea wave 2ch(2channel, ni channeru) acquaintances of information and representation to analyze the causes of this Japanese anti-Korean thinking. All of society should be aware of the differences and see what we have in common. I researched discussions of 2ch information and the content of other similar media. The expression was very violent. However, there was both general awareness of a gap between criticism and support. The gap was about what is not unusual on the Internet and not to be greatly concerned about. I also compares anti-Korean's awareness to Korea with general Japanese's, and finds that there are gap between them. For example by analyzing general Japanese's awareness we can find 18% of people who criticize the Hate Korea wave or have positive image of Korea. futhermore the proportion of anti-Korean contents in internet is not very high, so we don't have to worrying about the phenomenon seriously. but because of the following three points, there are sufficient needs to concern about the phenomenon constantly. First, sources of Hate Korea wave are traditional media. Second, the consumers of Hate Korea wave are mainly young generation who will make future relation of two countries. And last, Hate Korea wave include potential power to explode when certain conditions are met.

• Journal of the Korean Association of Geographic Information Studies
• /
• v.7 no.4
• /
• pp.77-87
• /
• 2004

It is important for hydrographers to extract the accurate cross section of a river for the hydrographical analysis of the topography. Aerial photographs were used to extract the cross section of a river for the advantages of the accuracy and economical efficiency in this study, while the direct measurement has been used in existing studies. An ortho-rectified photo map using imageries taken by the PKNU 2 (High-resolution, multi-spectral, aerial photographic system developed by our laboratory) was generated using the surveyed data and a digital map. The cross section of a river that was obtained from the ortho-rectified by the surveyed Kinematic data of GPS was compared with the result using ImageStation stereo-plotter of corp. Z/I Imaging. As a result of this study, the RMSE in the ortho-rect process using the surveyed GPS data was lowered as from 5.5788 pixels (about 2m) to 2.84 (about 1m) in comparison with it in the process using a digital map. The surveyed kinematic GPS in extraction of the cross section of a river was excellent as 6.6cm of the planimetric and precision in the confidence level of 95%. The correlation coefficient between the result from the using stereo-plotter and the extraction of cross section of a river using aerial photos was 0.8 hydrographical acquisition of it using PKNU 2 imagery will be possible.

• Journal of the Korean Data and Information Science Society
• /
• v.24 no.1
• /
• pp.117-124
• /
• 2013

Association rule of data mining techniques is the method to quantify the relationship between a set of items in a huge database, andhas been applied in various fields like internet shopping mall, healthcare, insurance, and education. There are three primary interestingness measures for association rule, support and confidence and lift. Confidence is the most important measure of these measures, and we generate some association rules using confidence. But it is an asymmetric measure and has only positive value. So we can face with difficult problems in generation of association rules. In this paper we apply the similarity measures by probabilistic interestingness measure (PIM) with all marginal proportions (AMP) to solve this problem. The comparative studies with support, confidences, lift, chi-square statistics, and some similarity measures by PIM with AMPare shown by numerical example. As the result, we knew that the similarity measures by PIM with AMP could be seen the degree of association same as confidence. And we could confirm the direction of association because they had the sign of their values, and select the best similarity measure by PIM with AMP.

• International Journal of Oral Biology
• /
• v.36 no.3
• /
• pp.117-122
• /
• 2011

Endothelial cells are a vital constituent of most mammalian organs and are required to maintain the integrity of these tissues. These cells also play a major role in angiogenesis, inflammatory reactions, and in the regulation of thrombosis. Angiogenesis facilitates pulp formation and produces the vessels which are essential for the maintenance of tooth homeostasis. These vessels can also be used in bone and tissue regeneration, and in surgical procedures to place implants or to remove cancerous tissue. Furthermore, endothelial cell regeneration is the most critical component of the tooth generation process. The aim of the present study was to stimulate endothelial regeneration at a site of acute cyclophosphamide (CP)-induced endothelial injury by treatment with human umbilical cord-derived endothelial/mesenchymal stem cells (hEPCs). We randomly assigned 16 to 20-week-old female NOD/SCID mice into three separate groups, a hEPC ($1{\times}10^5$ cells) transplanted, 300mg/kg CP treated and saline (control) group. The mice were sacrificed on days 5 and 10 and blood was collected via the abdominal aorta for analysis. The alanine transaminase (ALT), aspartate aminotransferase (AST), serum alkaline phosphatase (s-ALP), and albumin (ALB) levels were then evaluated. Tissue sections from the livers and kidneys were stained with hematoxylin and eosin (HE) for microscopic analysis and were subjected to immunohistochemistry to evaluate any changes in the endothelial layer. CP treatment caused a weight reduction after one day. The kidney/body weight ratio increased in the hEPC treated animals compared with the CP only group at 10 days. Moreover, hEPC treatment resulted in reduced s-ALP, AST, ALT levels compared with the CP only group at 10 days. The CP only animals further showed endothelial injuries at five days which were recovered by hEPC treatment at 10 days. The number of CD31-positive cells was increased by hEPC treatment at both 5 and 10 days. In conclusion, the CP-induced disruption of endothelial cells is recovered by hEPC treatment, indicating that hEPC transplantation has potential benefits in the treatment of endothelial damage.

• Child Health Nursing Research
• /
• v.19 no.1
• /
• pp.29-38
• /
• 2013

Purpose: This study was done to develop a cell phone addiction scale for Korean parents of young children, and to evaluate the reliability and validity of the developed scale. Methods: The scale was developed through construction of a conceptual framework, generation of initial items, verification of content validity, selection of secondary items, preliminary study, and extraction of final items. Participants were 465 parents and 178 children. Data were analyzed using item analysis, factor analysis, criterion related validity, internal consistency, and split-half reliability. Results: Twenty items were categorized into three factors explaining 60.3% of total variance. Factors were named as withdrawal - 4 items, loss of control - 9 items, and persistence - 7 items. Scores for the scale were significantly correlated with self-control, impulsiveness, cell phone use, and cell phone addiction of children as measured by a scale for Korean children. Cronbach's alpha coefficient for the 20 items was .94, and Guttman coefficient was .87. Scale scores identified children as high risk users, at risk users, or average users by standard scores. Conclusion: The results suggest that the cell phone addiction scale for Korean parents is a reliable and valid instrument to measure cell phone addiction in young children.