• 한국정보과학회논문지:소프트웨어및응용
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• 제35권3호
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• pp.189-196
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• 2008

본 논문은 복잡한 실시간 환경에서 인간의 의사결정을 대체하는 자율적인 에이전트의 구축을 위하여 필수적인 지식베이스의 형성과정을 제안하며, 지식베이스의 형성과정에 대한 방법론을 실질적인 응용 도메인에서 검증한다. 한국형 헬기의 두뇌역할을 수행하는 생존체계장비가 실시간 전장 환경에서 여러 개의 센서로부터 수신하는 위협 데이타를 분석하고, 위협 데이타의 특성과 위협간의 상호 연관성을 컴파일 과정을 통하여 귀납적 모델로 정형화한다. 규범화된 상황-행동 규칙은 헬기가 복잡한 전장 환경에서 실시간 추론 시간을 줄이며, 자율적으로 위협에 대처할 수 있는 능력을 갖추도록 할 것이다. 제안한 방법론의 검증을 위하여 한국형 헬기의 위협을 실험적으로 분류하였으며, 컴파일 과정이 위협을 성공적으로 탐지할 수 있음을 보여주었다.

• 한국항행학회논문지
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• 제11권2호
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• pp.203-208
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• 2007

정보시스템에서 다루는 정보 및 정보시스템은 조직의 기능을 유지함과 동시에 임무를 완수하는데 필요한 중요 자원이므로, 정보의 비인가된 누출, 변경, 손실 혹은 정보시스템의 침해로부터 파생되는 문제점은 경제적 손실뿐만 아니라 조직의 지속성 차원에서도 중요한 의미를 갖게 된다. 경쟁관계에서의 생존을 위해 신속성, 정확성 측면에서 중요한 역할을 수행하여 온 정보시스템에 치명적 오류 혹은 침해가 발생하는 경우, 해당 정보시스템에 의존하고 있는 조직의 생존성은 지대한 영향을 받을 수 있다. 따라서 각 조직은 중요 정보시스템을 안전하게 보호하기 위해 상당한 투자를 아끼지 않고 있으며, 이러한 노력은 몇 가지 특징들을 나타내면서 발전되어 왔다. 이러한 중요 정보시스템을 보호하기 위해서는, 먼저 누가 정보시스템에 대해 위협을 가할 수 있는지를 파악하여야 하며, 위협을 야기하는 위협원의 특징에 따라 보안대책을 수립하여야 한다. 본 논문에서는 중요 정보시스템에 위협을 가할 수 있는 위협원들을 식별하고, 이들의 특징을 정리하였으며, 위협원의 위험성을 가시적으로 표시하기 위해 가중치를 부여하는 방법을 제안하였다.

• 융합보안논문지
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• 제15권2호
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• pp.43-55
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• 2015

교육망의 보안 인프라는 통합관리시스템을 기준으로 다양한 정보보호시스템의 보안 이벤트를 수집하고 분석을 통하여 위협을 관리하고 대응한다. 이러한 체계는 관리자에게 유용하고 자세한 정보를 제공하지만, 다양한 위협 상황과 동시 다발적인 위협에 대해서 효과적인 대응 프로세스와 관리체계를 제공하지 못하고 있는 문제점을 많이 가진 교육망에 대한 해결방안으로 관리자에게 다양하고 세부적인 정보 제공보다는 관리자가 초기 위협에 신속하게 대응할 수 있도록 관리기술과 다양한 보안 이벤트들의 처리 스케줄링을 통해서 통합보안관리가 가능하도록 보안 에이전트를 제안 개발하였다.

• 한국재난정보학회 논문집
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• 제1권1호
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• pp.3-26
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• 2005

In recent years, there is growing concern about the potential use of biological agents in war or acts of terrorism accompanied an increased realization that rapid preparedness and response are needed to prevent or treat the human damage that can be caused by these agents. The threat is indeed serious, and the potential for devastating numbers of casualties is high. The use of agents as weapons, even on a small scale, has the potential for huge social and economic disruption and massive diversion of regional and national resources to combat the threat, to treat primary disease, and to clean up environmental contamination. Biological weapons are one of weapons of mass destruction (or mass casualty weapons, to be precise. since they do not damage non-living entities) that are based on bacteria, viruses, rickettsia, fungi or toxins produced by these organisms. Biological weapons are known to be easy and cheap to produce and can be used to selectively target humans, animals, or plants. Theses agents can cause large numbers of casualties with minimal logistical requirements (in wide area). The spread of disease cannot be controlled until there is awareness of the signs of infection followed by identification of agents; and if the organism is easily spread from person to person, as in the case of smallpox, the number of casualties could run into the tens of thousands. Biological weapons could be used covertly, there can be a lot of different deployment scenarios. A lot of different agents could be used in biological weapons. And, there are a lot of different techniques to manufacture biological weapons. Terrorist acts that make use of Biological Agents differ in a number of ways from those involving chemicals. The distinction between terrorist and military use of Biological Weapon is increasingly problematic. The stealthy qualities of biological weapons further complicate the distinction between terrorism and war. In reality, all biological attacks are likely to require an integrated response involving both military and civilian communities. The basic considerations when public health agencies establish national defence plan against bioterrorism must be 1) arraying various laws and regulations to meet the realistic needs, 2)education for public health personnels and support of concerned academic society, 3)information collection and cooperative project with other countries, 4)Detection and surveillance(Early detection is essential for ensuring a prompt response to biological or chemical attack, including the provision of prophylactic medicines, chemical antidotes, or vaccines) and 5) Response(A comprehensive public health response to a biological or chemical terrorist event involves epidemiologic investigation, medical treatment and prophylaxis for affacted persons, and the initiation of disease prevention or environmental decontamination measures). The purpose of this paper is providing basic material of preparedness and response for biological terrorism in modern society.

• 유통과학연구
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• 제14권6호
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• pp.53-63
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• 2016

Purpose - This study examines the effects of the influence strategies on sales representative and headquarter trust, and investigates how sales representative trust plays a mediating role in the relationship between influence strategies and headquarter trust. For these purposes, a structural model which consists of several constructs was developed. In this model, influence strategies that consist of relational influence strategies (information exchange, recommend, promise) and mandatory influence strategies (legal plea, request, threat) were proposed to affect the sales representative trust and in turn, increase the headquarter trust. Thus, this study proposed that sale representative trust plays a core mediating role in the relationship between relational and mandatory influence strategies and headquarter trust in B2B food materials distribution context. Research design, data, and methodology - For these purposes, the authors collected the data from 208 B2B specialized complex agents. We used the 2,200 B2B specialized complex agents which trade with CJ, Ottogi, and Daesang firms and supply food materials to restaurant, school cafeteria, supermarket and traditional market as a sample frame. Once we identified 330 B2B specialized complex agent owners, CEOs, and/or Directors who had agreed to participate in this study, we dropped off a questionnaire at each B2B specialized complex agent and explained the purpose of this study. The survey was conducted from October 1, 2015 to December 15, 2015. A total of 230 questionnaires were collected. Of these collected questionnaires, 28 questionnaires excluded since they had not been fully completed. The data were analyzed using frequency test, reliability test, measurement model analysis, and structural equation modeling with SPSS and SmartPLS 2. Results - First, information exchange, recommendation, and promise of relational influence strategies had positive effects on sales representative trust. The threat of mandatory influence strategies had a negative effect on sales representative trust, but legal plea and request did not have a significant effect on sales representative trust. Second, information exchange and recommendation of relational influence strategies had positive effects on headquarter trust, but promise did not. Also, legal plea, request, and threat of mandatory influence strategies did not have a significant effect on headquarter trust. Third, this findings show that sales representative trust plays a partial mediator between information exchange and headquarter trust, and threat and headquarter trust, and a full mediator between promise and headquarter trust, and recommendation and headquarter trust. Conclusions - The aim of this study was to examine the effects how diverse dimensions of relational and mandatory influence strategies relate to sales representative trust and headquarter trust. To do so, we integrated the influence strategies and the trust transfer theory to hypothesize that various influence strategies increase sales representative and headquarter trust. The findings of this study suggest that headquarter firms should establish and enforce proper influence strategies guidelines to make clear what proper actions sales representatives should implement in relationship with B2B specialized complex agents. Also, relational and mandatory influence strategies must be regarded as a long-term and ongoing strategy that eventually build a long-term orientation with B2B specialized complex agents and guarantee a company's sustainable growth and success.

• 융합보안논문지
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• 제17권2호
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• pp.53-68
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• 2017

오늘날 정보공유는 점차 지능화, 고도화되어 나타나고 있는 사이버공격을 효과적으로 예방할 수 있는 수단으로 인식되어 미국, EU, 영국, 일본 등 전세계적으로 국가적 차원의 사이버 위협정보 공유체계를 구축하고 있다. 특히 미국은 지난 2015년 12월 "사이버위협정보공유법(CISA)"을 제정하는 등 오래전부터 위협정보 공유를 위한 법 제도 기반 마련, 수행체계 구축 이행을 추진해오고 있다. 우리나라는 국가사이버안전센터와 한국인터넷진흥원을 중심으로 각각 공공, 민간분야에서 사이버 위협정보를 수집, 공유하고 있으며 관련 법 제도의 도입 시행을 통한 일원화된 정보공유 절차의 마련과 수행체계 구축을 추진 중에 있으나, 사이버 위협정보 공유 과정에서 발생할 수 있는 기업 또는 개인의 민감정보 유출문제, 정보수집 관리 주체에 대한 신뢰, 효용성 등의 문제의 우려도 제기되고 있는 실정이다. 본 논문에서는 미국과 우리나라의 사이버 위협정보 공유 현황의 비교 분석을 통해 향후 우리나라의 성공적인 사이버 위협정보 공유 체계정착이 이루어지는데 필요한 요구사항 및 시사점을 도출해보고자 한다.

• Journal of Microbiology and Biotechnology
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• 제29권1호
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• pp.1-10
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• 2019

Gram-negative pathogens, such as Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii, pose a serious threat to public health worldwide, due to high rates of antibiotic resistance and the lack of development of novel antimicrobial agents targeting Gram-negative bacteria. The outer membrane (OM) of Gram-negative bacteria is a unique architecture that acts as a potent permeability barrier against toxic molecules, such as antibiotics. The OM is composed of phospholipids, lipopolysaccharide (LPS), outer membrane ${\beta}-barrel$ proteins (OMP), and lipoproteins. These components are synthesized in the cytoplasm or in the inner membrane, and are then selectively transported to the OM by the specific transport machines, including the Lol, BAM, and Lpt pathways. In this review, we summarize recent studies on the assembly systems of OM components and analyze studies for the development of inhibitors that target these systems. These analyses show that OM assembly machines have the potential to be a novel attractive drug target of Gram-negative bacteria.

• Natural Product Sciences
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• 제28권3호
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• pp.93-104
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• 2022

Methicillin-resistant Staphylococcus aureus (MRSA) is a serious threat to the global healthcare system. Ineffective and resistance to antibiotic treatments have increased morbidity and mortality rates worldwide. New and effective antibiotics are needed to combat against bacterial resistance. Endophytic fungi are crucial reservoirs of novel bioactive metabolites. In particular, the secondary metabolites show promising therapeutic potential, notably, antibacterial. This review discussed the emerging potential of endophytic fungi as anti-MRSA agents. The ecological sources of endophytic fungi were discussed with the synthesis of bioactive metabolites. The mode of antibacterial actions was elucidated to give a better understanding of the mechanisms involved. This review may serve as an important reference for future discovery and developments of anti-MRSA agents from endophytic fungi.

• 한국군사과학기술학회지
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• 제25권2호
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• pp.210-217
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• 2022

Chemical warfare agents(CWA) such as nerve agents and vesicating agents show lethality by skin contamination. Skin protection, therefore, is one of the top priorities to deal with the growing threat from CWA. In an attempt to develop the most effective topical skin protectant(TSP), candidate substances including PFPE(perfluorinated polyether), PTFE(polytetrafluoroethylene), glycerin, and polysaccharides were evaluated in forms of various formulations against nerve agent simulant DMMP(dimethylmethyl phosphonate) penetration. The protective efficacy of the formulation against DMMP penetration was estimated as the onset time of color change of the KM9 chemical agent detection paper. Based on this study, it was found that several PFPE- and glycerin-based formulations exhibit remarkably superior efficacy as a protective cream. This protective cream is expected to be used as TSP for military application after further research.

• 대한의생명과학회지
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• 제24권2호
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• pp.55-63
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• 2018

Microbes and their toxins can be bioweapons that bioterrorists use them to commit bioterrorism and biocrime. Due to the potential and relative ease of the bioattack, life-threat pathogenic agents (bacteria, viruses, and toxins) as bioweapon revealed the need for a new field of microbial forensics. Microbial forensics is a new scientific discipline combining microbiology and forensic science, which is focused on characterization of evidence from a bioterrorism, biocrime, and an inadvertent release of biothreat agents. The sophisticated analytical tool and knowledge of microbial forensics can provide investigative leads and help determine who was responsible for the biocrime, the source of the bioweapon, and how and where the bioweapon was produced. Among the fields of microbial forensics, this paper will briefly describe evidence collection, handling, packaging, transportation, storage, analytical methods of evidence, and review microbial forensics as a response to bioterrorism and biocrime.