• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.20 no.9
• /
• pp.2981-2990
• /
• 1996

Dual solutions for steady natural convection of air between two horizontal concentric cylinders are numerically investigated in the range of $D_i$/TEX>/L(=diameter of inner cylinder/gap width)$\leq$10. It is found that, when the Rayleigh number based on the gap width exceeds a certain critical value, a new flow pattern forming two counter-rotating eddies in the half of the annulus can be realized, which is different from the crescent-shaped flow commonly observed. In the new flow pattern, the fluid near the top of the hot inner cylinder moves downward. This solution is found for D$_{i}$/L.geq.0.3, but not for$D_i$/TEX>/L$\leq$0.2. As $D_i$/TEX>/L increase, the critical Rayleigh number is decreased, and tends to a finite limit.t.

• Biomolecules & Therapeutics
• /
• v.21 no.6
• /
• pp.423-434
• /
• 2013

The adoption of oligonucleotide aptamer is well on the rise, serving an ever increasing demand for versatility in biomedical field. Through the SELEX (Systematic Evolution of Ligands by EXponential enrichment), aptamer that can bind to specific target with high affinity and specificity can be obtained. Aptamers are single-stranded nucleic acid molecules that can fold into complex three-dimensional structures, forming binding pockets and clefts for the specific recognition and tight binding of any given molecular target. Recently, aptamers have attracted much attention because they not only have all of the advantages of antibodies, but also have unique merits such as thermal stability, ease of synthesis, reversibility, and little immunogenicity. The advent of novel technologies is revolutionizing aptamer applications. Aptamers can be easily modified by various chemical reactions to introduce functional groups and/or nucleotide extensions. They can also be conjugated to therapeutic molecules such as drugs, drug containing carriers, toxins, or photosensitizers. Here, we discuss new SELEX strategies and stabilization methods as well as applications in drug delivery and molecular imaging.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 1998.03a
• /
• pp.88-93
• /
• 1998

The service life of tools in metal forming process is to a large extent limited by wear, fatigue fracture and plastic deformation. In warm forging processes wear is the predominant factor for operating lives of tools. To predict tool life by wear, Archard's wear model is generally applied. Usually hardness of die is considered to be a function of temperature in Archard's wear model. But hardness of die is a function of not only temperature but also operating time of die. To consider softening of die by repeated operations, it is necessary to express hardness of dies by a function of temperatures and operating time. By experiment of reheating of dies, die softening curves were obtained. Finally modified Archard's wear model in which hardness of die was expressed as a function of main tempering curve was proposed.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
• /
• 2006.11a
• /
• pp.209-212
• /
• 2006

Line heating with water cooling is generally adapted process in the shipyards for the forming hull surface. The purpose of this paper is to develop a model of thermal deformation in water cooling process after the line heating. In order to simulate the cooling process, heat transfer analysis was performed by assuming the effects of water cooling as a negative heat-source. Experiment for the line heating with water cooling was performed for 9 models of plates in order to verify the cooling model. By using the suggested model for the water cooling process, it could be observed that the present method predict the plate deformations in the line heating more accurately.

• Textile Coloration and Finishing
• /
• v.20 no.4
• /
• pp.31-42
• /
• 2008

Tricrecyl phosphate(TCP)-containing polyurea microcapsules were prepared by interfacial polymerization using aromatic 2,4-toluene diisocyanate(TDI) and ethylenediamine(EDA) as wall forming materials. The effects of the protective colloids of polyvinylalcohol(PVA) and gelatin were investigated through experimentation. The mean size of prepared polyurea microcapsules was smaller and the surface morphology of the microcapsule prepared by the PVA as protective colloid was much smoother than the gelatin. As the concentration of protective colloid increased, the wall membrane of the polyurea microcapsules became more stable, the thermal stability of the wall membrane increased, the mean particle size became smaller, and the particle distribution was more uniform. PET containg microTCPs have a higher activation energy of decomposition, higher char content and lower heat of combustion.

• Design & Manufacturing
• /
• v.2 no.1
• /
• pp.39-43
• /
• 2008

There occur not only many problems in the injection process but also low quality productivity due to the injection conditions of various injection factors. Injection molding process factors such as molding temperature, injection pressure, flow rate and flow velocity, must be controlled properly in filling and packing phases in the injection molding process. In this study, effects of these factors on the injection molding were investigated through the flow analysis for the holding pressure affecting cooling time. Results of this study would be helpful to setting of holding pressure for optimization of forming condition in order to reduce cooling time in injection molding.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2002.10a
• /
• pp.641-645
• /
• 2002

In case of aluminum-cased battery, The ratio of height and base of square is generally above the ten times, square-shaped and problem of non-axis symmetry. It is typical model to set up the analysis method of finite element. The reliable analysis of finite element method is suggested, which is used to investigate the possibility that multi-stage deep drawing and ironing used currently is replaced by backward impact extrusion favorable in the respect of cost production and productivity. The influence of parameter was analyzed and compared, which was considered to analyze the process of large deformation plasticity such as extrusion. Die and billet was made as the same shape of finite element model. The results of experiment show good forming without the rupture and wrinkles with the optimum velocity 100mm/sec obtained by analysis.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.5 no.2
• /
• pp.186-190
• /
• 2004

By this time, a mold with nano size pattern was produced using a fabrication of X-ray lithography method and in a m icro size's case it was produced using fabrication of Deep UV lithography. In this paper, we produced mold with 400 $\mu{m}$depth pattern using a new technology of SLS(Selective Laser Sintering) Rapid Prototyping method. In addition to enhance strength and thermal stability, we produced Ni structure with a thickness of 300 $\mu{m}$ on a surface of mold using electro forming method.

• 전기의세계
• /
• v.21 no.1
• /
• pp.13-16
• /
• 1972

Dynamic Programming is regarded as a very powerful tool for solving nonlinear optimization problem subject to a number of constraints of state and control variables, but has definite disadvantages that it requires much more computing time and consumes much more memory spaces than other technigues. In order to eliminate the above-mentioned demerits, this paper suggests a news technique called Multiple Dynamic Programming. The underlying principles are based on the concept of multiple passes that, instead of forming fin lattices in time-state plane as adopted in the conventional Dynamic Programming, the Multiple Dynamic Programming constitutes, at the first pass, coarse lattices in the feasible domain of time-state plane and determines the optimal state trajectory by the usual method of Dynamic Programming, and at the second pass again constitutes finer lattices in the narrower domain surrounded by both the upperand lower edges next to the lattice edges through which the first pass optimal trajectory passes and determines the more accurate optimal trajectory of state, and then at the third pass repeats the same processes, and so on. The suggested technique insures remarkable curtailment in amounts of computer memory spaces and conputing time, and its applicability has been demonstrated by a case study on the hydro-thermal power coordination in Korean power system.

• Journal of the Korean Ceramic Society
• /
• v.41 no.7
• /
• pp.497-502
• /
• 2004

A hybrid coextrusion and lamination process has been developed to fabricate macrochanneled bioceramic scaffolds. This process was mainly composed of three steps (i.e., coextrusion of thermoplastic compound, lamination, and thermal treatment), forming unique pore channels in dense bioceramic body. Pore channels were formed by removing carbon black material, while calcium phosphate or Tetragonal Zirconia Polycrystals (TZP) with a calcium phosphate coating layer were used as dense body. Two kinds of pore structures were fabricated; that is, the pore channels were formed in uni- or three-directional array. Such macrochanneled bioceramic scaffolds exhibited the precisely controlled pore structure (pore size, porosity, and interconnection), offering excellent mechanical properties and cellular responses.