• Radiation Oncology Journal
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• v.4 no.1
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• pp.75-80
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• 1986

Heterotopic bone formation is a complication which occurs in 0.6 to $61.7\%$ of patients after total hip replacement arthroplasty. We reviewed 4 patients (8 hips) who received postoperative irradiation on their hi ps for prevention of heterotopic bone formation in the Department of Therapeutic of Therapeutic Radiology, Seoul National University versify Hospital from January 1981 through August 1985. Radiation therapy was started 6 to 10 days postoperatively with the dosage of 2,000 cGy given in 10 fractions. As a result, 7 hips had Grade 0 and 1 hip had Grade 1 heterotopic ossification according to modified Blocker system. Our result and review of the literatures strongly support that the postoperative radiotherapy is effective for prevention of heterotopic bone formation in high risk group.

• Child Health Nursing Research
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• v.24 no.4
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• pp.517-526
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• 2018

Purpose: This study compared nursing frequency, nursing time, and nursing intervention priorities depending on the method of neonatal induced hypothermia. Methods: We observed 15 neonatal subjects receiving therapeutic hypothermia for 3 days each. Forty-five nurses experienced with nursing neonatal patients under therapeutic hypothermia provided responses about nursing intervention priorities. Analyses with the chi-square, the Fisher exact test, the paired t-test, the Wilcoxon signed rank test, and the Wilcoxon rank-sum test were performed on the data using SAS version 9.4. Results: The frequency of nursing activities was higher for selective head therapeutic hypothermia (SHTH) than for systemic therapeutic hypothermia (STH), and nursing time was also significantly longer. In terms of nursing intervention priorities, there were priority differences in "risk for ineffective thermoregulation" and "risks for impaired skin integrity" for SHTH compared to STH. Conclusion: Since SHTH for neonatal therapeutic hypothermia requires more nursing time and frequent nursing activities than STH, STH is therefore recommended if the therapeutic efficacy is similar. Appropriate nursing personnel should be allocated for neonatal SHTH nursing. Nurses should be aware of nursing interventions for therapeutic hypothermia as the priorities are different for different methods of neonatal therapeutic hypothermia.

• Journal of Society of Preventive Korean Medicine
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• v.4 no.2
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• pp.25-56
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• 2000

Trace element are involved in enzymatic activities, immunological reactions. physiological mechanisms. Deficiency in some trace elements, such as iron and iodine. is still an important health problem, The role of trace elements deficiency is suspected in various clinical situations and is now confirmed by well designed supplementation studies. However, the importance of trace elements as chinese herbal constituents is not sufficiently appreciated by the oriental medical profession, although in recent years a significant increase of new finding on their essential character in chinese herbal medicine occurred. It is well known that herbal medicine contains a variety of trace elements which would show therapeutic effects with active components in herbal medicine . In china, recent work showed some positive correlation between trace element and traditional chinese medicine (TCM) in terms of therapeutic effects even if their role in therapeutic effects is still obscure. In korea, not much attention has been on the therapeutic importance of trace element contained in herbal medicine Here, the therapeutic effects of trace element in TCM were reviewed and summarized. 1. Iron, copper, zinc and manganese are mainly contained in TCM. In addtion, chromium, magnesium, molybdenum, nickel, alminium, cobalt, arsenic and selenium has been studied for their therapeutic effects 2. Zinc, is decreased in patients who have deficiency of kindney(腎虛) and chronic disease. Fe is decreased in patients who have deficiency of blood(血虛). However copper is increased in patients who have chronic disease and hepatic disease.3 Iron concentration is high in herbs used for tonifying and nourishing yin or blood(補陰補血藥) Zinc concentration is high also in herb used for tonifying kidiney and vital essence(補腎補精藥). In addition. copper concentration Is high in herb used for replenishing qi(補氣藥) 4 In herbal drugs, the therapeutic substances in TCM are not only organic but also inorganic. It seems that trace elements would be one of components in herb for its therapeutic effects. This indicates that therapeutic effects of TCM should be extended not only to herb itself, bur also to trace elements contained in herb.

• BMB Reports
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• v.44 no.6
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• pp.359-368
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• 2011

Polycystic kidney disease (PKD) is a common genetic disorder in which extensive epithelial-lined cysts develop in the kidneys. In previous studies, abnormalities of polycystin protein and its interacting proteins, as well as primary cilia, have been suggested to play critical roles in the development of renal cysts. However, although several therapeutic targets for PKD have been suggested, no early diagnosis or effective treatments are currently available. Current developments are active for treatment of PKD including inhibitors or antagonists of PPAR-${\gamma}$, TNF-${\alpha}$, CDK and VEGF. These drugs are potential therapeutic targets in PKD, and need to be determined about pathological functions in human PKD. It has recently been reported that the alteration of epigenetic regulation, as well as gene mutations, may affect the pathogenesis of PKD. In this review, we will discuss recent approaches to PKD therapy. It provides important information regarding potential targets for PKD.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.712-713
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• 2017

Clinically applicable light emitting diode (LED) has been widely investigated because of relatively low heat generation, low cytotoxicity, and non-invasiveness compared to other therapeutic methods. Therefore, we investigated the therapeutic effects of several wavelengths of light emitting diode against human cervical cancer cells and analyzed the individual inhibitory effect for the cancer cell proliferation. In the experiment, prepared HeLa cells were exposed by red, green and blue light-emitting diode for 10 minutes each. Relatively short-wavelength light-emitting diode (blue) showed stronger therapeutic effects than relatively long-wavelength light-emitting diodes.

• The Journal of Korean Society for Radiation Therapy
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• v.1 no.1
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• pp.79-83
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• 1985

Carcinoma of the breast has been treated by surgery followed by irradiation of the chest wall and regional lymphatics treatment planning of the breast cancer is required that lung must be spared as much as possible. However megavoltage irradiation of the internal mammary chain results in high dose to underlying heart, esophagus and spinal cord. Electron beam can be used for the irradiation of the internal mammary chain instead of megavoltage beam. We studied dose distribution of single anterior electron field, compared with traditional treatment methods. 12 and 15MeV electron beam with bolus has good dose distribution to spare underlying lung tissue and other organs.

• Asian-Australasian Journal of Animal Sciences
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• v.23 no.5
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• pp.672-679
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• 2010

Diabetes mellitus is a worldwide epidemic with high mortality. As concern over this disease rises, the number and value of research grants awarded by the National Research Foundation of Korea (NRF) have increased. Diabetes mellitus is classified into two groups. Type 1 diabetes requires insulin treatment, whereas type 2 diabetes, which is characterized by insulin resistance, can be treated using a variety of therapeutic approaches. Hyperglycemia is thought to be a primary factor in the onset of diabetes, although hyperlipidemia also plays a role. The major organs active in the regulation of blood glucose are the pancreas, liver, skeletal muscle, adipose tissue, intestine, and kidney. Diabetic complications are generally classified as macrovascular (e.g., stroke and heart disease) or microvascular (i.e., diabetic neuropathy, nephropathy, and retinopathy). Several animal models of diabetes have been used to develop oral therapeutic agents, including sulfonylureas, biguanides, thiazolidinediones, acarbose, and miglitol, for both type 1 and type 2 diseases. This review provides an overview of diabetes mellitus, describes oral therapeutic agents for diabetes and their targets, and discusses new developments in diabetic drug research.

• Radiation Oncology Journal
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• v.18 no.1
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• pp.46-50
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• 2000

A 70 years old female patient with thyroid cancer received palliative radiation therapy for neck swelling and hemoptysis. She had a cardiac pacemaker under her chest due to complete AV block since 8 years ago. We present clinical detail and review previously reported articles.

• The Journal of Korean Society for Radiation Therapy
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• v.6 no.1
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• pp.89-93
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• 1994

Authors have measured virtual source distance of electron beam from CL/1800 medical linear accelerator, with newly designed method. Beam scanning was performed with the direction of beam axis in the air. Compared results between this study and well established in phantom measurement shows good agreement with in experimental error. And we have found that build-up cap plays very important role in air measurement because of charge build up. The method of in-air measurement of virtual source distance is very easy to set-up and generate accurate results.

• International Journal of Advanced Culture Technology
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• v.5 no.1
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• pp.26-31
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• 2017

In this study, Emotion-DNA is constructed in the same way asthat the human DNA constructs the human body. Emotion-DNA is copied and translated in the same way as that the human DNA copies and translates itself. We made an attempt to embody the mind by Emotion-DNA like the symbols "A, T, G, C, U" that make up the chromosome of the human body. This is a diagram of the flow of emotions that the human body operates by literary works. These schemes present new directions for the therapeutic analysis of literary works and for the creation of therapeutic literary works. In this study, we analyzed the nominal Emotion-syllables as a framework of the structuring of emotional DNA. As a result, through the structuring of the emotional DNA, it was judged that the therapeutic action of the human body, which is included in the Rated Sijo among the literary works, can be more concrete and powerful than the works of other genres.