• Title/Summary/Keyword: The weight reduction design

Search Result 690, Processing Time 0.026 seconds

Optimization of Process Variables for Grinding of Ibuprofen using Response Surface Methodology (반응표면분석법을 이용한 이부프로펜의 분쇄공정변수의 최적화)

  • Sim, Chol-Ho
    • Korean Chemical Engineering Research
    • /
    • v.51 no.6
    • /
    • pp.685-691
    • /
    • 2013
  • Ibuprofen, non-steroidal anti-inflammatory drugs; NSAIDs, is a highly crystalline substance with the pharmaceutical properties of poor solubility and low bioavailability. The size reduction of ibuprofen is needed to improve the solubility. The objective of this study is to optimize the grinding condition of ibuprofen. Grinding of ibuprofen was carried out using a planetary mill. Grinding parameters were optimized using Box-Behnken experimental design method. The physical characteristics of ground ibuprofen were investigated for the particle size by particle size analyzer, for the crystal size by X-ray diffraction (XRD), and for the tensile strength by tensile/compression tester. The optimum conditions for the milling of ibuprofen were 290 rpm of the revolution number of mill, 24.6 g of the weight of sample, and 10 minutes of grinding time. The measured value of the particle size of ground ibuprofen at these optimum conditions was $13.5{\mu}m$. The results showed that the crystal size of ibuprofen was reduced by the planetary milling process. In case the relative density of the tablets formulated of ground ibuprofen was range of 0.85~0.90, the tensile strength of them was range of 1$2{\sim}14Kg_f/cm^2$.

절수의 시기 및 방법의 차이가 수도의 생육수량과 기타 실용형질에 미치는 영향

  • 이창구
    • Journal of the Korean Professional Engineers Association
    • /
    • v.1 no.1
    • /
    • pp.18-25
    • /
    • 1968
  • Higher yield in rice paddies is greatly dependent on adequately balanced and timely supply of water. A majority of rice paddy in Korea is generally irrigated by rainfall, but in many cases it has to be supplemented by artificial irrigation for optimum rice culture. Although the water requirement of rice plant is for higher Than that of athec crops, submerged condition of rice paddy is not Necessarily required. The moisture requirement of rice plant varies with its growing stages, and it is possible to increase the irrigation efficiency through reduction of water loss due to percolation in rice paddies. An experimental plots were set up by means of sandomized block design with three duplication; (a) All time submerged, (b) Economically controlled, and (c) Extremely controlled. Three different irrigation periods Were (a) Initial sage, (b) Inter-stage, and (c) Yast stage. The topsoil of the three plots were excavated to the depth of 30 cm and then compacted with clay of 6 cm thickness. There after, they were piled up with the excavated top soils, leveled and cored with clay of 6 cm thickness around footpath in order to prevent leakage. The results obtained from the experiments are as follows, 1. There is no difference among the three experiments plots in terms of physical and chemical conditions, soil properties, and other characteristics. 2. Culm length and ear length are not affected by different irrigation methods. 3. There is no difference in the mature rate and 1, 000 grain weight of rice for the three plots. 4. The control plot which was irrigated every three days shows an increased yield over the all the time submerged plot by 17.8 percent. 5. The clay lined plot whose water holding capacity was held 5 days long, needs only to be irrigated every 7 days. 6. The clay lined plot shows an increased yield over the untreated plot ; over all-the-time submerged plot by 18 percent ; extremely controlled plot by 18 percent, and economically controlled plot by 33 percent. 7. It may be saved in water requirement about one Thirds.

  • PDF

Numerical Investigation of the Progressive Failure Behavior of the Composite Dovetail Specimens under a Tensile Load (인장하중을 받는 복합재료 도브테일 요소의 점진적인 파손해석)

  • Park, Shin-Mu;Noh, Hong-Kyun;Lim, Jae Hyuk;Choi, Yun-Hyuk
    • Composites Research
    • /
    • v.34 no.6
    • /
    • pp.337-344
    • /
    • 2021
  • In this study, the progressive failure behavior of the composite fan blade dovetail element under tensile loading is numerically investigated through finite element(FE) simulation. The accuracy of prediction by FE simulation is verified through tensile testing. The dovetail element is one of the joints for coupling the fan blade with the disk in a turbofan engine. The dovetail element is usually made of a metal material such as titanium, but the application of composite material is being studied for weight reduction reasons. However, manufacturing defects such as drop-off ply and resin pocket inevitably occur in realizing complex shapes of the fan blade made by composite materials. To investigate the effect of these manufacturing defects on the composite fan blade dovetail element, we performed numerical simulation with FE model to compare the prediction of the FE model and the tensile test results. At this time, the cohesive zone model is used to simulate the delamination behavior. Finally, we found that FE simulation results agree with test results when considering thermal residual stress and through-thickness compression enhancement effect.

Analysis of Variables Influencing the Pressure Build-up and Volume Expansion of Kimchi Package (김치포장의 압력 및 부피 변화에 영향을 미치는 인자의 분석)

  • 이동선;최홍식;박완수
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.28 no.2
    • /
    • pp.429-437
    • /
    • 1999
  • A mathematical model was established for estimating changes in pressure and volume of permeable kimchi packages. The model comprises the CO2 gas production from kimchi and permeation of O2, CO2 and N2 through the permeable film or sheet. Using the developed model, the effects of various packaging variables on the pressure and volume changes were analyzed for rigid and flexible packag es of kimchi(3% salt content) at 15oC, and then effect of storage temperature was also looked into. In case of rigid pack of 400g, using the plastic sheet of high CO2 permeability and initial vacuumizing can help to relieve the problem of pressure build up. The lower fill weight can further reduce the pressure, but will result in higher packaging cost. For the flexible package of 3 kg, highly permeable films such as low density polyethylene(LDPE) and polypropylene can reduce the volume expansion. Higher ratio of CO2 permeability to O2 and N2 permeabilities are effective in reducing the volume expansion. Increased surface area cannot contribute to reduction of volume expansion for highly permeable flexible packages of kimchi. For the impermeable packages, pressure and volume at over ripening stage (acidity 1.0%) increase with decreased temperature, while those at optimum ripening stage(acidity 0.6%) change little with temperature. Pressure of permeable rigid LDPE package increases with tem perature at any ripening stage, and temperature affects the volume of flexible LDPE package very slightly. Experimental verification of the present results and package design with economical consid eration are needed as a next step for practical application.

  • PDF

Mechanical and durability of geopolymer concrete containing fibers and recycled aggregate

  • Abdelaziz Yousuf, Mohamed;Orhan, Canpolat;Mukhallad M., Al-Mashhadani
    • Computers and Concrete
    • /
    • v.30 no.6
    • /
    • pp.421-432
    • /
    • 2022
  • Recently, the interminable ozone depletion and the global warming concerns has led to construction industries to seek for construction materials which are eco-friendly. Regarding this, Geopolymer Concrete (GPC) is getting great interest from researchers and scientists, since it can operate by-product waste to replace cement which can lead to the reduction of greenhouse gas emission through its production. Also, compared to ordinary concrete, geopolymer concrete belongs improved mechanical and durability properties. In spite of its positive properties, the practical use of geopolymer concrete is currently limited. This is primarily owing to the scarce structural, design and application knowledge. This study investigates the Mechanical and Durability of Geopolymer Concrete Containing Fibers and Recycled Aggregate. Mixtures of elastoplastic fiber reinforced geopolymer concrete with partial replacement of recycled coarse aggregate in different proportions of 10, 20, 30, and 40% with natural aggregate were fabricated. On the other hand, geopolymer concrete of 100% natural aggregate was prepared as a control specimen. To consider both strength and durability properties and to evaluate the combined effect of recycled coarse aggregate and elastoplastic fiber, an elastoplastic fiber with the ratio of 0.4% and 0.8% were incorporated. The highest compressive strength achieved was 35 MPa when the incorporation of recycled aggregates was 10% with the inclusion of 0.4% elastoplastic fiber. From the result, it was noticed that incorporation of 10% recycled aggregate with 0.8% of the elastoplastic fiber is the perfect combination that can give a GPC having enhanced tensile strength. When specimens exposed to freezing-thawing condition, the physical appearance, compressive strength, weight loss, and ultrasonic pulse velocity of the samples was investigated. In general, all specimens tested performed resistance to freezing thawing. the obtained results indicated that combination of recycled aggregate and elastoplastic fiber up to some extent could be achieved a geopolymer concrete that can replace conventional concrete.

Design of Heuristic Decision Tree (HDT) Using Human Knowledge (인간 지식을 이용한 경험적 의사결정트리의 설계)

  • Yoon, Tae-Tok;Lee, Jee-Hyong
    • Journal of the Korean Institute of Intelligent Systems
    • /
    • v.19 no.4
    • /
    • pp.525-531
    • /
    • 2009
  • Data mining is the process of extracting hidden patterns from collected data. At this time, for collected data which take important role as the basic information for prediction and recommendation, the process to discriminate incorrect data in order to enhance the performance of analysis result, is needed. The existing methods to discriminate unexpected data from collected data, mainly relies on methods which are based on statistics or simple distance between data. However, for these methods, the problematic point that even meaningful data could be excluded from analysis due that the environment and characteristic of the relevant data are not considered, exists. This study proposes a method to endow human heuristic knowledge with weight value through the comparison between collected data and human heuristic knowledge, and to use the value for creating a decision tree. The data discrimination by the method proposed is more credible as human knowledge is reflected in the created tree. The validity of the proposed method is verified through an experiment.

Apparent or Standardized Ileal Digestibility of Amino Acids of Diets Containing Different Protein Feedstuffs Fed at Two Crude Protein Levels for Growing Pigs

  • Adebiyi, A.O.;Ragland, D.;Adeola, O.;Olukosi, O.A.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.28 no.9
    • /
    • pp.1327-1334
    • /
    • 2015
  • The current study determined the apparent or standardized ileal digestibility of amino acids (AID or SID of AA) in growing pigs fed diets containing three protein feedstuffs with different fiber characteristics at two dietary crude protein (CP) levels. Twenty boars ($Yorkshire{\times}Landrace$) with average initial body weight of $35({\pm}2.6)kg$ were fitted with a simple T-cannula at the distal ileum. These pigs were offered six diets containing soybean meal (SBM), canola meal (CM) or corn distillers dried grains with solubles (corn-DDGS) that were either adequate (19%) or marginal (15%) in CP using a triplicated $6{\times}2$ Youden Square Design. Except for Met, Trp, Cys, and Pro, AID of AA was greater (p<0.05) in the SBM diet compared with the CM diet. Apparent ileal digestibility for Gly and Asp was greater (p<0.05) in the SBM diet compared with the corn-DDGS diet. The AID of Ile, Leu, Phe, Val, Ala, Tyr, and Asp was greater (p<0.05) in the corn-DDGS diet compared with the CM diet. Standardized ileal digestibility of AA was greater (p<0.05) in the SBM diet compared with the CM diet for all AA except Trp and Pro. The SID of Ile, Leu, Val, Ala, Tyr, and Asp was greater (p<0.05) in the corn-DDGS diet compared with the CM diet. It was concluded that protein feedstuff affects ileal AA digestibility and is closely related to dietary fiber characteristics, and a 4-percentage unit reduction in dietary CP had no effect on ileal AA digestibility in growing pigs.

Impact Energy Absorbing Capability of Metal/Polymer Hybrid Sheets (금속/폴리머 접합강의 충격 특성에 대한 실험적 연구)

  • Kong, Kyungil;Kwon, O Bum;Park, Hyung Wook
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.41 no.2
    • /
    • pp.137-142
    • /
    • 2017
  • Recently, the reduction of vehicle weight has been increasingly studied, in order to enhance the fuel efficiency of passenger cars. In particular, the seat frame is being studied actively, owing to considerations of driver safety from external impact damage. Therefore, this study focuses on high strength steel sheet (SPFC980)/polymer heterojunction hybrid materials, and their performance in regards to impact energy absorption. The ratio of impact energy absorption was observed to be relatively higher in the SPFC980/polymer hybrid materials under the impact load. This was found by calculating the equivalent flexural rigidity, which is the bending effect, according to the Castigliano theorem. An efficient wire-web structure was investigated through the simulation of different wire-web designs such as triangular, rectangular, octagonal, and hexagonal structures. The hexagonal wire-web structure was shown to have the least impact damage, according to the simulations. This study can be utilized for seat frame design for passengers' safety, owing to efficient impact absorption.

A Study on the Miniaturization of Angle Head Spindle Case for Cutting in Narrow Spaces (협소 공간 절삭가공용 앵글 헤드 스핀들 케이스 소형화에 대한 연구)

  • Sung, Chul Hoon;Han, Sung Gil;Kim, Sung Hoon;Song, Chul Ki
    • Journal of the Korean Society of Manufacturing Process Engineers
    • /
    • v.18 no.6
    • /
    • pp.98-105
    • /
    • 2019
  • In order to improve the fuel economy and dynamic behavior of automobiles, the weight reduction tendency of automobile parts is obvious. Also, in order to maximize assembly and maintenance convenience, various parts are integrated and modularized. Multi-piece methods require many manufacturing processes and become a factor of lowering the strength of parts. It is advantageous to overcome the disadvantages by integrally manufacturing to reduce the processing steps and ensure the strength of the parts. However, when it is necessary to process in a narrow space inside the part, it is impossible to process with the existing spindle. The angle head spindle is only a component of a machine tool, but it is a core part that requires high technology and is highly utilizable in products requiring high precision machining. Therefore, various and continuous studies needs for angle head spindles in areas such as vibration absorption, operational safety, excellent dimensional stability, and strength. In this paper, we propose an optimal design for angle head spindle by performing structural analysis and shape optimization for angle head spindle gear and case.

Effect of Foliar and Root Application of Silicon Against Rice Blast Fungus in MR219 Rice Variety

  • Abed-Ashtiani, Farnaz;Kadir, Jugah-Bin;Selamat, Ahmad-Bin;Hanif, Ahmad Husni Bin-Mohd;Nasehi, Abbas
    • The Plant Pathology Journal
    • /
    • v.28 no.2
    • /
    • pp.164-171
    • /
    • 2012
  • Rice blast disease caused by Magnaporthe grisea (Hebert) Barr [teleomorph] is one of the most devastating diseases in rice plantation areas. Silicon is considered as a useful element for a large variety of plants. Rice variety MR219 was grown in the glasshouse to investigate the function of silicon in conferring resistance against blast. Silica gel was applied to soil while sodium silicate was used as foliar spray at the rates of 0, 60, 120, 180 g/5 kg soil and 0, 1, 2, 3 ml/l respectively. The treatments were arranged in a completely randomized design. Disease severity and silicon content of leaves were compared between the non-amended controls and rice plants receiving the different rates and sources of silicon. Silicon at all rates of application significantly (${\alpha}$ = 0.05) reduced the severity of disease with highest reduction (75%) recorded in treatments receiving 120 g of silica gel. SEM/EDX observations demonstrated a significant difference in weight concentration of silicon in silica cells on the leaf epidermis between silicon treated (25.79%) and non treated plants (7.87%) indicating that Si-fertilization resulted in higher deposition of Si in silica cells in comparison with non-treated plants. Application of silicon also led to a significant increase in Si contents of leaves. Contrast procedures indicated higher efficiency of silica gel in comparison to sodium silicate in almost all parameters assessed. The results suggest that mitigated levels of disease were associated with silicification and fortification of leaf epidermal cells through silicon fertilization.