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Synthesis and Characterization of Poly(L-lactic acid-co-glycine-L-lactic acid) and Poly - ( L-1actic acid-co-gl ycine-L-methyl 1actic acid) (생체분해성 고분자의 합성 및 물성에 관한 연구(II) -Poly (L-lactic acid-co-glycine-L-lactic acid) 와 Poly- (L-lactic acid-co-glycine-L-methyl lactic acid))

  • Sung, Yong-Kiel;Song, Dae-Kyung;Park, Kyung-Hee
    • Journal of Biomedical Engineering Research
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    • v.9 no.2
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    • pp.225-232
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    • 1988
  • Poly (L- lactic acid-co-glycine-L-lactic acid) and Poly (L-lactic acid-co-glycine-L- methyl lactic acid ) have been prepared by ring opening polymerization. The monomer 6, 6-dimethyl morpho-line-2, 5-dione was synthesized by the bromoisobutylation of 2-bromoisobutyryl bromide with glycin e. L-lactide, 6-methyl morpholine-2, 5-diode. and 6, 6-dimethyl morpholine-2, 5-diode have been used as starting materials for polydepsipeptides. The synthesized monomers and copolymers have been identified by NMR and FT-lR spa- ctrophotometer. The thermal propert ies and glass transition temperature(Tg) of the copolymers have been measured by differential scanning calorimetry. The Tg values of poly(L-lactic acid co-glycine-L-lactic acid) system are increased from $53^{\circ}C\; to\; 107^{\circ}C$ with increasing the mole fraction of 6-methyl morpholine-2, 5-diode. And the Tg values of poly(L-lactic acid co-glycine-L-methyl lactic acid) system are increased from $53^{\circ}C\;to\;138^{\circ}C$ with increasing the mole fraction of 6. 6-dimethyl morpholine-2, 5-diode The thermal stability of poly (L-lactic acid-co-glycine-L-methyl lactic acid) is slightly greta text than that of poly(L-lactic acid-co-glycine-L-lactic acid) due to the methyl group.

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A Study of Home-furnishing Products Strategy through the Consumption Tendency Analysis of Single Household (1인 가구의 소비성향 분석을 통한 홈퍼니싱 제품전략 연구)

  • Kim, Taesun
    • Journal of the Korea Furniture Society
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    • v.27 no.3
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    • pp.237-245
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    • 2016
  • Single households currently account for 26.5% of all households and their number is expected to continue to rise, reaching 34.5% by 2035. An analysis of the consumption trends and needs of single households shows that they are rising as a new consumer group with a focus on investment on the individual and favouring: small but high-tech products: efficient use of limited resources: safety and peace of mind: self-improvement and leisure. Products which meet such demands are having an impact on the growth of home-furnishing market. An analysis of companies in Korea's home-furnishing market, with examples like the lifestyle company IKEA, shows a variety of brands such as SPA brand, furniture specialist, distributor and character products. And yet most are OEM products which lack differentiated product lines and compete with similar display and distribution structure. We needs the Single household consumption tendency of home-furnishing market and differentiation strategy through product analysis. In order to increase the value of companies in the home-furnishing market, in addition to differentiated design, product competitiveness must aspire to higher customer satisfaction with easy assembly, innovation in logistics, innovative sales methods such as virtual-reality simulation for products and space, individually-tailored furniture for the needs of single household and products which combine smart technology. For home-grown home-furnishing brands to have competitiveness, they must leverage on the strengths of the industry, offering differentiated and competitive products in a wider range of areas with convergence functions as well as differentiation in consumer interface and application of advancing technology; in-depth product research is called for.

The Effect of Other Customer Perceptions on Male Customers' Store Attitude and Behavioral Response in Fashion Store (남성 소비자의 패션 점포 내 다른 고객 특성 지각이 점포 태도와 행동에 미치는 영향)

  • Kim, Boram;Lee, Yuri;Kim, Yunjeong
    • Journal of the Korean Society of Clothing and Textiles
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    • v.40 no.1
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    • pp.41-55
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    • 2016
  • This study analyzed the influence of other customers' perception (similarity, physical attraction, and suitable behavior) of the fashion retail environment on male customers' store attitude and behavioral response. In addition, comparing the effect of store type, this study comprehensively provides the effect of other customers' perception in fashion retailing. In order to investigate research questions, an online survey was conducted and 220 responses were analyzed using AMOS 18.0. The results of this research were as follow. First, the dimensions of physical attraction and suitable behavior of other customers influenced toward target customer's fashion store attitude. Second, the effect of store attitude towards the perceiver's behavioral response was proven. Third, customers established their store attitude by other customers' physical attraction in luxury stores, while others' behavior was meaningful in SPA store. Fourth, other customer's similarity dimension did not influence the male customers' store attitude. This study contributes to a comprehensive understanding of other customer's effect in fashion stores by examining different store types. In addition, managers may establish a customer portfolio strategy and training based on this research.

Livestock-associated methicillin-resistant Staphylococcus aureus in Korea: antimicrobial resistance and molecular characteristics of LA-MRSA strains isolated from pigs, pig farmers, and farm environment

  • Back, Seung Hyun;Eom, Hong Sik;Lee, Haeng Ho;Lee, Gi Yong;Park, Kun Taek;Yang, Soo-Jin
    • Journal of Veterinary Science
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    • v.21 no.1
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    • pp.2.1-2.14
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    • 2020
  • The emergence of livestock-associated (LA)-methicillin-resistant Staphylococcus aureus (MRSA) in livestock animal has become a significant zoonotic concern. In the present study, we investigated nationwide prevalence of LA-MRSA across pork production chain including pig farms, slaughterhouses, and retail markets. A total of 40 MRSA strains were isolated during the investigation and the overall prevalence of MRSA was 3.4% (n = 37), 0.6% (n = 2), and 0.4% (n = 1) in pig farms, slaughterhouses, and retail markets, respectively. Multilocus sequence typing analyses revealed that the 2 most significant clonal lineages in pork production chain in Korea were ST398 (n = 25) and ST541 (n = 6). All of the 40 MRSA isolates were further characterized to investigate key genotypic and phenotypic correlates associated with the emergence and spread of clonal complex 398 (CC398; ST398, and ST541) LA-MRSA. Although the prevalence of swine-associated MRSA was still relatively low and mostly restricted to pig farms, multidrug-resistant CC398 LA-MRSA isolates with new spa types (t18102 and t18103) were identified as a major clonal lineage. The CC398 LA-MRSA strains tended to exhibit increased levels of multiple drug resistance (MDR) phenotype compared with non-CC398 MRSA strains. Of note, in comparison with non-CC398 MRSA isolates, CC398 LA-MRSA isolates exhibited significantly enhanced tetracycline (TET) and zinc resistance. These findings suggested that co-selection pressure associated with MDR phenotype, especially TET resistance, and zinc resistance may have played a significant role in the emergence and persistence of CC398 LA-MRSA in pig farms in Korea.

Analysis of Operating and Maintenance Parameters for Agricultural Pipeline System Using EPANET (EPANET을 이용한 농업용 관수로 시스템의 운영 및 유지관리 인자 분석)

  • Kim, Nam Do;Kim, Sun Joo;Kwon, Hyung Joong;Kim, Phil Shik;Park, Hyun Jun
    • Journal of The Korean Society of Agricultural Engineers
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    • v.59 no.4
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    • pp.17-26
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    • 2017
  • In this study, EPANET model which is using on the pipe network analysis was applied to Haenam irrigation district has provided irrigation water by pipeline system about 1,125ha and then have built pipe network to study area and supply performance evaluation of existing structure was analyzed by SPA (Single Period Analysis) in EPANET. As model results of simulation average ratio of maximum supply quantity/irrigation water requirements(base demand) was analyzed by 2.63. It means also that was analyzed as being capable of ensuring the water supply capacity. It was provided the necessary information for the maintenance facility through analyzed hydraulic behaviors in the pipeline inside such as flow velocities, pressures and hydraulic grade lines. It was satisfied with the allowable design criteria that was compared analyzed results with presented allowable design standards at agricultural production infra improvement project planning and design (Pipeline design standard). In order to analyze efficiency promotions of irrigation water, using Extended Period Simulation it was compared supply quantity with irrigation water requirements while pumps set operating pattern in 24 hours, then efficiency promotions of irrigation water was determined through analyzed oversupply water quantity and occurrence time by branch lines. According to results for oversupply quantity in Haenam district by time and end of branch lines efficiency promotions of irrigation water was suggested from 0.33 % to 37.59 %. To draw reasonable operating rules for water use and through this research, it is expected to be helpful for efficient water use and operational management of agricultural pipeline system to the current agricultural irrigation.

Geochemical Characteristics of Groundwater in Korea with Different Aquifer Geology and Temperature -Comparative Study with Granitic Groundwater (대수층 지질 및 온도에 따른 국내 지하수의 지구화학적 특징 -화강암질암내 지하수와의 비교연구)

  • 이종운;전효택;전용원
    • Journal of the Korean Society of Groundwater Environment
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    • v.4 no.4
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    • pp.212-222
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    • 1997
  • Geochemistry of metasedimentary groundwaters and spar waters has been studied in comparison with that of granitic groundwaters in Korea. Metasedimentary groundwaters show $Ca^{2+]$-${HCO_3}^-$ type at depth and low sodium concentrations compared with granitic groundwaters, which is due to the lack of plagioclase in their aquifer mineralogy and, therefore, the predominant reaction of calcite dissolution. According to factor analysis, metasedimentary groundwaters at 100~300 m depth are represented by 1) the dissolution of calcite and Mg-carbonates, 2) transformation of kaolinite to illite, and 3) the presence of sodium as not the product of plagioclase dissolution but a artificial pollutant. Discriminant function between the granitic and metasedimentary groundwaters shows a good discriminating ability with 81.8%, and groundwaters of volcanic aquifer, which has abundant plagioclase, are included in the granitic group by this function. Spa water samples show the result of active water-rock interaction due to high temperature.

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Validity of bag urine culture for predicting urinary tract infections in febrile infants: a paired comparison of urine collection methods

  • Kim, Geun-A;Koo, Ja-Wook
    • Clinical and Experimental Pediatrics
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    • v.58 no.5
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    • pp.183-189
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    • 2015
  • Purpose: Catheter urine (CATH-U) and suprapubic aspiration (SPA) are reliable urine collection methods for confirming urinary tract infections (UTI) in infants. However, noninvasive and easily accessible collecting bag urine (CBU) is widely used, despite its high contamination rate. This study investigated the validity of CBU cultures for diagnosing UTIs, using CATH-U culture results as the gold standard. Methods: We retrospectively analyzed 210 infants, 2- to 24-month-old, who presented to a tertiary care hospital's pediatrics department between September 2008 and August 2013. We reviewed the results of CBU and CATH-U cultures from the same infants. Results: CBU results, relative to CATH-U culture results (${\geq}10^4$ colony-forming units [CFU]/mL) were widely variable, ranging from no growth to ${\geq}10^5CFU/mL$. A CBU cutoff value of ${\geq}10^5CFU/mL$ resulted in false-positive and false-negative rates of 18% and 24%, respectively. The probability of a UTI increased when the CBU bacterial count was ${\geq}10^5/mL$ for all infants, both uncircumcised male infants and female infants (likelihood ratios [LRs], 4.16, 4.11, and 4.11, respectively). UTIs could not be excluded for female infants with a CBU bacterial density of $10^4-10^5$ (LR, 1.40). The LRs for predicting UTIs based on a positive dipstick test and a positive urinalysis were 4.19 and 3.11, respectively. Conclusion: The validity of obtaining urine sample from a sterile bag remains questionable. Inconclusive culture results from CBU should be confirmed with a more reliable method.

In Vivo Measurement of Site-Specific Peritoneal Solute Transport Using a Fiber-Optic-based Fluorescence Photobleaching Technique

  • Lee, Donghee;Kim, Jeong Chul;Shin, Eunkyoung;Ju, Kyung Don;Oh, Kook-Hwan;Kim, Hee Chan;Kang, Eungtaek;Kim, Jung Kyung
    • Journal of the Optical Society of Korea
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    • v.19 no.3
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    • pp.228-236
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    • 2015
  • Fluorescence recovery after photobleaching (FRAP) is a well-established method commonly used to measure the diffusion of fluorescent solutes and biomolecules in living cells or tissues. Here a fiber-optic-based FRAP (f-FRAP) system was developed, and validated using macromolecules in water and agarose gels of different concentrations. We applied f-FRAP to measure the site-specific diffusion of fluorescein (NaFluo) in peritoneal membranes (PMs) on the liver, cecum, and kidney of a living rat during peritoneal dialysis. Diffusion of fluorescein in PM varied in a time-dependent manner according to the type of organ ($D_{PM\;on\;Liver}/D_{NaFluo}=0.199{\pm}0.085$, $D_{PM\;on\;Cecum}/D_{NaFluo}=0.292{\pm}0.151$, $D_{PM\;on\;Kidney}/D_{NaFluo}=0.218{\pm}0.110$). The proposed method allows direct quantitative measurement of the three-dimensional diffusion in local PM in vivo, which was previously inaccessible by peritoneal function test methods such as peritoneal equilibration test (PET) and standardized PM assessment (SPA). f-FRAP is promising for local and dynamic assessments of peritoneal pathophysiology and the mass transport properties of PMs, presumed to be affected by variation of tissue structures over different organs and functional changes of the PM with years of peritoneal dialysis.

The Effects of Interpersonal Relationship Stress on Job Attitude and Turnover Intention: Focused on Hotel Employees in Food and Beverage Department (대인관계 스트레스가 직무태도와 이직의도에 미치는 영향: 호텔 식음료 종사원을 대상으로)

  • Baek, Jong-Chul;Shin, Hyoung-Chul;Kang, Hee-Seog
    • Culinary science and hospitality research
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    • v.24 no.3
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    • pp.133-143
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    • 2018
  • The purposes of this study was to investigate how interpersonal relationship stress had the impact on job attitude and turnover intention. To perform this study, total 420 questionnaire were distributed to regular hotel employees from October 16th to November 26th in 2017. Unworkable data were excluded, and final 344 usable responses were obtained for an empirical analysis. Frequency analysis, exploratory factor analysis, reliability analysis, correlation analysis and regression analysis were measured by using SPSS 18.0, respectively. For the study structure, interpersonal relationship stress primarily concentrated on the boss/staff/colleague/customer stress. Job attitude was divided into organization commitment and job satisfaction. Transfer intention was a single factor. The results of this study were shown as follows: Hypothesis 1, boss/customer stress have a negative effect on organization commitment and boss/colleague/customer stress have a negative effect on job satisfaction. Hypothesis 2, boss/customer stress have a positive effect on transfer intention. Hypothesis 3, tissue commitment have a negative effect on transfer intention. This results of this study have shown that stress management of employee is a source of management result in hotel business. This study have given to the hotel's human resource management and internal marketing for the practical implication and academical use.

Induction of In Vitro Vitellogenin Synthesis by Bisphenol, Nonylphenol and Octylphenol in Chinese Minnow(Phoxinus oxycephalus) Hepatocytes

  • Park, Chang-Beom;Kim, Byung-Ho;Na, Oh-Soo;Choi, Young-Chan;Lee, Young-Don;Baek, Hae-Ja;Kim, Hyung-Bae;Akihiro Takemura
    • Animal cells and systems
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    • v.7 no.3
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    • pp.227-235
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    • 2003
  • Bisphenol A (BPA), nonylphenol (NP), and 4-tert-octylphenol (OP) are known endocrine disrupting chemicals (EDCs) with estrogenic activity in fish. This study compared the effects of BPA, NP and OP on in vitro vitellogenin (VTG) synthesis in primary cultures of hepatocytes of the Chinese minnow Phoxinus oxycephalus. The VTG secreted into the culture medium was measured using enzyme-linked immunosorbent assay (ELISA), which we developed in this study using an antibody prepared from homogenates of Chinese minnow egg. VTG synthesis was induced by estradiol-17$\beta$ ($E_2$) and phenols (BPA, NP and OP) treatment. $E_2$ at concentrations of 10$^{-6}$ M or higher increased VTG levels significantly (P < 0.05). Exposure to 10^5\;M\;BPA\;or\;10^-4$M NP and OPinduced in vitro VTG synthesis (P < 0.01). However, $10^-3$ M BPA, NP or OP did not induce VTG synthesis. These results suggest that SPA has the highest estrogenic potential in Chinese minnow hepatocytes. Tamoxifen, an anti-estrogen, drastically blocked the production of VTG by phenols (BPA, NP and OP) suggesting that phenols (BPA, NP and OP) may act via binding to estrogen receptor (ER) in Chinese minnow hepatocytes.