• Journal of The Korean Society of Grassland and Forage Science
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• v.29 no.3
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• pp.197-210
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• 2009

To improve the forage quality and reduce nitrogen input, trial was conducted on the effect of seeding method, combination, and nitrogen fertilizer with WCB (whole crop barley) and leguminous plant. Present experiment was carried out by split-split design having seeding methods for main plot, combinations for sub-plot, and nitrogen fertilizers for sub-sub plot with three replications. When WCB and leguminous plant were mixed-sown, WCB showed earlier heading and maturing than those of inter-sown, and the more nitrogen delayed growth stage a little. Occurrence of BaYMV (Barley Yellow Mosaic Virus), a serious disease caused by soil fungi and decrease barley yield, was deterred by mixed-seeding as compared to inter-sown barley a little. Inter-sown WCB increased the number of spike per $m^2$ as compared to mixed-seeding showing more spikes with nitrogen increase. WCB produced much fresh and dry matter yield at mixed-seeding than inter-seeding, and had advantage with hairy vetch (HV). Increased nitrogen showed much forage yield, however, half application of it is considerable for environmental-friendly farming. Electric conductivity (EC) decreased in inter-cropping or mixed-sowing soil with WCB and leguminous crop after harvest. But, organic matter (OM) content of soil after harvesting was vice versa. Acid detergent fiber (ADF) and Neutral detergent fiber (NDF) of WCB plant were higher at mixed-seeding than those of inter-sown ones. It showed increased tendency with time progress.

• Journal of Life Science
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• v.21 no.5
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• pp.720-728
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• 2011

Garlic (Allium sativum) has been used as a source food as well as a traditional folk medicine ingredient since ancient times. Aged black garlic is a type of fermented garlic and is expected to have stronger anticancer and antioxidant activities than raw garlic. However, the mechanisms of their inhibitory effects on adipocyte differentiation and adipogenesis are poorly understood. In the present study, the effects and mechanisms of water extracts of raw garlic (WERG) and aged black garlic (WEABG) on adipocyte differentiation and adipogenesis in 3T3-L1 preadipocytes were investigated. Treatment with WEABG significantly suppressed terminal differentiation of 3T3-L1 preadipocytes in a dose-dependent manner as confirmed by a decrease in lipid droplet number and lipid content through Oil Red O staining, however WERG had no such effect. In addition, WEABG reduced accumulation of cellular triglyceride, which is associated with a significant inhibition of key pro-adipogenic transcription factors including peroxisome proliferator-activated receptor ${\gamma}$ (PPAR${\gamma}$), cytidine-cytidine-adenosine-adenosine-thymidine (CCAAT)/enhancer binding proteins ${\alpha}$ (C/EBP${\alpha}$) and C/EBP${\beta}$. Taken together, these results provide important new insight that aged black garlic might inhibit adipogenesis by suppressing the pro-adipogenic transcription factors in 3T3-L1 preadipocytes, and further studies will be needed to identify the active compounds that confer the anti-obesity activity of aged black garlic.

• Journal of agricultural medicine and community health
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• v.29 no.1
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• pp.91-100
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• 2004

Objectives: This study was conducted to compare the present community health practitioners(CHPs)'s operating activities with their activity in 1989. Methods: Data were obtained two hundred seventy eight CHPs by self-administered questionnaire regarding duty traits, job satisfaction, and others. Results: The number of CHPs was 255 in 1989 and 224 in 2000. Age of CHPs in 2000 was much higher than that in 1989, and married women was 64.9% in 1989 and 95.9% in 2000. Both the primary duty of CHPs in 1989 and that in 2000 was medical service, and others(maternal health, infant health, family planning, and tuberculosis management, etc) are decreased in 2000, and community health service was added to duty of CHPs in 2000. 55% of CHPs in 1989 satisfied with their job, whereas about 80% of CHPs in 2000 satisfied with their job. The CHPs perceived that their primary necessary duty among requisite duty are medical practice(57.7%), health education(31.4%), and community health service(10.9%), in contrast, unnecessary duty are family planning(68.8%), tuberculosis management(11.1%), infant health(6.3%) maternal health(5.6%). Conclusions: These results suggest that there are such alteration of job satisfaction, needs and obstacles in duty traits of CHFs. These trend of duty traits are major issues to be caught for the health service in primary health post.

• Journal of Nutrition and Health
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• v.16 no.3
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• pp.209-215
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• 1983

In high sodium societies, the incidence in blood pressure with childhood growth is more abrupt than the rate of rise in low sodium populations. Thus, it appears that a lower level of dietary sodium intake is required to correct established hypertension and to prevent its appearance In present work, an investigation was made to estimate the correlation between urinary sodium, potassium and creatinine excretion, weight, height, upper arm circumference, blood pressures and the number of heart rate. Sixty- four children aged 12-16 years (41 boys and 23 girls) were measured. Twenty -four-hour urinary sodium and potassium excretion averaged 132.8 mEq and 42.1 mEq in boys, 126.4 mEq and 41.3 mEq in girls. Twenty- four -hour urinary creatinine excretion averaged 795.7 mg and 744.3mg in boys and girls, respectively. Systolic and diastolic blood pressure were 117.6mmHg and 49.7mmHg in boys, 95.5mmHg and 58.2mmHg in girls. Systolic blood pressure correlated positively weight, height and urinary creatinine but diastolic blood pressure correlated positively with upper arm circumference and negatively with urinary potassium. It was concluded that urinary sodium does not explain the blood pressure.

• Korean Journal of Food Science and Technology
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• v.49 no.6
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• pp.676-684
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• 2017

The present study aimed to examine the hepatoprotective effects of ethanol extracts from steam-dried ginseng berry (SGBE) in both $\text\tiny{D}$-Galactosamine/Lipopolysaccharide ($\text\tiny{D}$-GalN/LPS)-sensitized mice and in vitro models. Our results clearly demonstrated that SGBE significantly reduced the level of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and lactate dehydrogenase in blood, and $TNF{\alpha}$ was normalized in 8 h after the treatment with $\text\tiny{D}$-GalN/LPS. Coincidently, major organs remained unimpaired when compared to $\text\tiny{D}$-GalN/LPS control group. Moreover, p38, which stimulates expression of NAFLD-associated cytokines, was markedly inhibited when treated with SGBE. In vitro analysis revealed that the main components of SGBE, linoleic acid and ginsenoside Re/Rd, may play a role in protecting liver from $\text\tiny{D}$-GalN/LPS-induced toxicity. Finally, we concluded that SGBE may be a promising therapeutic agent for preventing damage to the liver.

• Journal of Nutrition and Health
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• v.42 no.6
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• pp.577-595
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• 2009

This study aimed to reanalyze energy and nutrient intakes of 2007 Korean Nutrition and Health Examination Survey (KNHANES) using CAN-Pro 3.0, a commonly used nutrient analysis software in Korea. Food items and their codes were selected from 2007 KNHANES dietary intake file and converted to food codes of CAN-Pro 3.0 nutrient database (NDB). Of the 1,324 total food items, 1,155 items were converted by direct matching, 123 items were matched using other items in CAN-Pro 3.0 NDB and 42 items were matched using external sources. Consumption frequencies of items converted by direct matching contributed 94.5% of total consumption. Nutrient intakes of 4,091 participants of 2007 KNHANES, over 1 year old, were recalculated using CAN-Pro 3.0 NDB and compared with intakes in 2007 KNHANES dietary intake file. Intakes for energy and all nutrients except protein and Vitamin C calculated by two NDBs were significantly different by paired t-test (p < 0.001), but significantly correlated by Pearson' correlation coefficients (p < 0.001). Percent differences between the NDBs ranged from 0.3% to 15.1%, low for protein, energy, vitamin C, iron, vitamin B$_2$ (below 5%) but high for phosphorus, retinol, vitamin A, and $\beta$-carotene (over 10%). Age group, sex, and their interactions significantly influenced six nutrients (p < 0.05). Intake levels of zinc, vitamin B6, vitamin E, folate and cholesterol were not available in 2007 KNHANES but were calculated by CAN-Pro 3.0. Mean intake levels of zinc, vitamin B$_6$, vitamin E, and folate by age and sex groups revealed that some groups had mean levels below RI (Recommended Intake) or AI (Adequate Intake) levels. Intake level of cholesterol was higher than the recommended level (below 300 mg/day) in some groups, especially males. Results of the present study indicate the need for comparable and more comprehensive NDB to be used for dietary assessment of KNHANES and other researches. More rigorous evaluation of nutrients which have not been reported in KNHANES is needed.

• The Journal of Korean Society for Radiation Therapy
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• v.18 no.2
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• pp.97-103
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• 2006

The purpose of this study is to understand preliminary education. level of understanding and the degrees of educational requirement for cancer patients on radiotherapy and to present the preliminary data to development of effective and practical patients treatment programs. Based on the abovementioned results of this study. Relationship betweendegrees of knowledge and demand for educational requirement for patients who are undertaking radiotherapy could be varied with different factors such as educational background, ages, regions of treatment, experience of symptoms. In general, patients do not have enough information, on the other hand, have very high demand for educational requirement. Customized education patients by patients would not be possible in reality. However, if we could provide standard for patients and establish systematic sessions during treatment based on this study, more and better patients satisfaction and results of treatments could be achieved.

• Journal of Ginseng Research
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• v.44 no.6
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• pp.815-822
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• 2020

Background: Recently, beneficial roles of ginsenoside F2 (GF2), a minor constituent of Panax ginseng, have been demonstrated in diverse inflammatory diseases. However, its roles in alcoholic liver inflammation and injury have not been clearly understood. Here, we investigated the underlying mechanism by which GF2 ameliorated alcoholic liver injury. Methods: To induce alcoholic liver injury, C57BL/6J wild type (WT) or interleukin (IL)-10 knockout (KO) mice were orally administered with ethanol (3 g/kg) or ethanol-containing GF2 (50 mg/kg) for 2 wk. Liver injury and infiltration of macrophages and neutrophils were evaluated by serum biochemistry and immunohistochemistry, respectively. The changes of hepatic immune cells were assessed by flow cytometry and polymerase chain reaction analysis. In vitro differentiation of naïve T cells was performed. Results: GF2 treatment significantly attenuated alcoholic liver injury, in which infiltrations of inflammatory macrophages and neutrophils were decreased. Moreover, the frequencies of Foxp3⁺ regulatory T cells (Tregs) increased but IL-17-producing T (Th17) cells decreased in GF2-treated mice compared to controls. Furthermore, the mRNA expression of IL-10 and Foxp3 was significantly increased, whereas IL-17 mRNA expression was suppressed in GF2-treated mice. However, these beneficial roles of GF2 were not observed in GF2-treated IL-10 KO mice, suggesting a critical role of IL-10. Similarly, GF2 treatment suppressed differentiation of naïve T cells into Th17 cells by inhibiting RORgt expression and stimulating Foxp3 expression. Conclusion: The present study suggests that GF2 treatment attenuates alcoholic liver injury by increasing IL-10 expression and Tregs and decreasing IL-17 expression and Th17 cells.

• Korean Chemical Engineering Research
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• v.53 no.1
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• pp.31-38
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• 2015

At present, carbon dioxide ($CO_2$) emission, which causes global warming, is a major issue all over the world. To reduce $CO_2$ emission directly, commercial deployment of $CO_2$ separation processes has been attempted in industrial plants, such as power plant, oil refinery and steelmaking plant. Besides, several studies have been done on indirect reduction of $CO_2$ emission from recycle of reducing gas (carbon monoxide or hydrogen containing gas) in the plants. Unlike many competing gas separation technologies, pressure swing adsorption (PSA) and membrane filtration are commercially used together or individually to separate a single component from the gas mixture. However, there are few studies on operation of sequential separation process of multi-component gas which has more than two target gas products. In this paper, process simulation model is first developed for two available configurations: $CO_2$ PSA-CO PSA-$H_2$ PSA and $CO_2$ PSA-CO PSA-$H_2$ membrane. Operation optimization and economic evaluation of the processes are also performed. As a result, feed gas contains about 14% of $H_2$ should be used as fuel than separating $H_2$, and $CO_2$ separation should be separated earlier than CO separation when feed gas contains about 30% of $CO_2$ and CO. The simulation results can help us to find an optimal process configuration and operation condition for separation of multicomponent gas with $CO_2$, CO, $H_2$ and other gases.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.9
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• pp.1161-1166
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• 2009

The purpose of the present study was to effect of red pepper seeds powder on antioxidative defense system and oxidative damage in rats fed high fat high cholesterol diet. Rats were divided into five experimental groups which are composed of normal diet group, high fat high cholesterol diet group, high fat high cholesterol diet with 5% red pepper seeds powder supplemented group (SA group), high fat high cholesterol diet with 10% red pepper seeds powder supplemented group (SB group), and high fat.high cholesterol diet with 15% red pepper seeds powder supplemented group (SC group). Supplementation of red seed pepper groups (SA, SB, and SC groups) resulted in increased activities of hepatic glutathione peroxidase and superoxide dismutase. However, there was no significant difference in the activity of hepatic catalase among all experimental groups. Hepatic superoxide radical contents in microsome and mitochondria were significantly reduced in red pepper seeds powder supplemented groups. Hepatic hydrogen peroxide contents in mitochondria were significantly reduced 15% red pepper seeds powder supplemented group. Hepatic carbonyl values in microsome were significantly reduced in 10% and 15% red pepper seeds powder supplemented groups. Thiobarbituric acid reaction substance (TBARS) values in liver and plasma were reduced in red pepper seeds powder supplemented groups. These result suggest that red pepper seeds powder may reduce oxidative damage by the activation of antioxidative defense system in rats high fat.high cholesterol diets.