• The Journal of Korean Medical History
• /
• v.22 no.1
• /
• pp.31-45
• /
• 2009

Eui Bang Shin Gam("醫方新鑑") is a classic on oriental medicines written by Shin Oh (新塢) Han Byung Lyun (韓秉璉) in 1913. It was written under the base of the writer's own experience as well as in the light of 36 other classics on oriental medicines such as Dong Eui Bo Gam ("東醫寶監"), Eui Hak Yip Mun ("醫學入門"), and Kyung Ak Jeon Seo ("景岳全書"). In an attempt to avoid difficult theories and list only the essential informations and formulas for clinical purposes, it attained its own characteristics of not only reorganizing Dong Eui Bo Gam in a pragmatic way but also explaining diseases classified in western medicines in oriental medicines' point of view as well as suggesting medicine formulas regarding such explanations. As a result, it is a complete and efficient medical classic through which one can gain knowledge in both classic oriental medicines and combination of western and oriental medicines. Its special features are making a separate chapter for cholera and Lao Zhai (勞瘵), which is also a contagious disease, and trying in the chapter to explain the diseases in words of oriental medicines; listing details of nine major epidemic and matching them with the diseases known in oriental medicines; and recording a case of enforcing sterilization and preventive injection against contagious diseases. The basic medical theory in Eui Bang Shin Gam are the yin-yang theory, the thesis of fire and water, the thesis of the exterior and the interior, Yun Qi Lun (運氣論), and four institutions of human body. In explaining the basic theories, the writer emphasized strengthening the yang of the body, under the influence of the thoughts of Zhang Ga Bin (張介賓). Since he put the importance of diagnosis first, the first chapter is about diagnosis. There are five different ways of diagnosing a patient mentioned in the book, and acupuncture, pulse, and medicines was considered crucial.

• Journal of Korean Medical classics
• /
• v.22 no.2
• /
• pp.337-347
• /
• 2009

"Dong-uisusebowon("東醫壽世保元")", written by Ijema(李濟馬), is about the treatment and prevention of diseases according to the four constitutions, Soeum, Soyang, Taeeum and Taeyang. He presents a precise pathogenic mechanism along with specific treatment methods of the Ulgwang(鬱狂) Syndrome which are Seungbo(升補) and Ikgiseung-yang[益氣而升陽] in comparing Mang-yang(亡陽) and Ulgwang Syndromes. However, in the case of the Mang-yang Syndrome, he merely presents formulas without mentioning details of the treatment methods. In this study, the formulas of the Mang-yang Syndrome and Ulgwang Syndrome were thoroughly compared and analyzed, leading to the conclusion that the concept of the Ikgi(益氣) method matches that of the Bojung-ikgitang(補中益氣湯) of Idongwon(李東垣), consisted of ingredients such as Ginseng, Radix Astragali, Radix Angelicae Gigantis, Rhizoma Atractylodis Macrocephalae etc,, and the concept of Seung-yang matches that of Gyejitang(桂枝湯). Furthermore, we have examined the addition of Radix Aconti Lateralis Preparata[附子] to the Ikgiseung-yang[益氣而升陽] method to be aimed at restoring the Yanggi(陽氣). Lastly, through comparison of formulas according to the progress of the Mang-yang Syndrome and Ulgwang Syndrome, we have presented a more detailed explanation of the concept of each treatment methods: the Mang-yang Syndrome focuses more on Seung-yang(升陽), Ulgwang leans more towards Ikgi(益氣).

• Journal of Oriental Physiology
• /
• v.14 no.2 s.20
• /
• pp.99-116
• /
• 1999

This study was undertaken to define the expression rule of six vital substances for human life(六氣) in Meridians and the rule of following of three ${\breve{U}}m$ and three Yan. In order to investigate the expression rule of six vital substances for human life(六氣), incident(標)-fundamental(本) and Ki of middle energizer(中氣) of three ${\breve{U}}m$ and three Yang(三陰三陽) were reviewed. 1, The rule of following is formed centering around fundamental Ki(本氣) between incident(標) and fundamental(本). And in case the ${\breve{U}}m$ and Yang (陰陽) disposition of incident(標) and fundamental(本) is different, whether the ${\breve{U}}m$ and Yang(陰陽) disposition of incident(標) and fundamental(本) is same as those of Ki of middle energizer(中氣), is the key point in following fundamental and activating of the vital energy(氣化). 2. As twelve channels(十二經脈) have not only fundamental Ki(本氣) but also Ki of middle energizer(中氣) at the same time, in expression of six vital substances for human life(六氣), if the fundamental Ki(本氣) is stronger, fundamental Ki(本氣) can be expressed or if the fundamental Ki(本氣) is weaker, Ki of middle energizer(中氣) can be expressed. 3. Twelve channels which is connected with each other through the relation of the interior and the exterior can be regarded as a system, in which Wind(風) and Fire(火), Dryness(燥) and Dampness(濕), Cold(寒) and Heat(熱) maintain balance through mutual control. 4. We can see that in the disease caused by the unbalance of six vital substances for human life(六氣), expression of six pathogenic factor and controlment of six vital substances for human life(六氣) are made up after the following one in the rule of following(從化規律).

• Proceedings of the Botanical Society of Korea Conference
• /
• 1998.07a
• /
• pp.10-18
• /
• 1998

For improvement of plants in disease resistance, it is most important to elucidate the mechanism to perceive and respond to the signal molecules of invaders. A model system with pea and its pathogen, Mycosphaerella pinodes, showed that the fungal elicitor induced defense responses in all plant species tested but that the suppressor of the fungus blocked or delayed the expression of defense responses and induced accessibility only in the host plant. In the world, many researchers believe that the pathogens` signals are recognized only on the receptors in the plasma membranes. Though we found that the ATPase and polyphosphoinositide metabolism in isolated plasma membranes responded to these fungal signals, we failed to detect specific actions of the suppressor in vitro on these plasma membrane functions. Recently, we found that ATPase (NTPases) and superoxide generating system in isolated cell wall were regulated by these fungal signals even in vitro, especially, by the suppressor in a strictly species-specific manner and also that the cell wall alone prepared an original defense system. The effects of both fungal signals on the isolated cell wall functions in vitro coincide perfectly with those on defense responses in vivo. In this treatise, we discuss the key role of the cell wall, which is plant-specific and the most exterior organelle, in determining host-parasite specificity and molecular target for improvement of plants.

• Journal of Korean Medical classics
• /
• v.29 no.2
• /
• pp.13-29
• /
• 2016

Objectives : The purpose of this study is to investigate the concept of the Chukbu(尺膚) diagnosis in Huangdineijing(黃帝內經) and explain the characteristic of Chukbu(尺膚) diagnosis and causes of its clinical applicational decline. It will help the application of the Chukbu(尺膚) diagnosis to clinical treatment. Methods : The Sikuquanshu(四庫全書) database and Traditional Chinese Medical(TCM) books web database were used. The related contents of the Chukbu(尺膚) diagnosis in Huangdineijing (黃帝內經) and its annotation books were analyzed. The mentions on the Chukbu(尺膚) diagnosis in other medical books were examined. Results & Conclusions : The Chukbu(尺膚) diagnosis is important in the diagnostic system of the Huangdineijing(黃帝內經). The Chukbu(尺膚) diagnosis is composed of inspection and palpation. Its characteristic is something different compared to that of the Chongumaek(寸口脈) diagnosis; it relatively diagnoses condition of exterior disease(表病). The causes of its clinical applicational decline are relative inconvenience, limits of feudal society, and development of Zangfubianzheng(臟腑辨證) in that era.

• Herbal Formula Science
• /
• v.17 no.1
• /
• pp.45-59
• /
• 2009

To beef up natural immunity, we have used Bojoongikgitang which has been known to treat enervation in the oriental medicine. This study is analyzed out structure material and the chief virtue of a prescription through Literature Study on Bojoongikgitang and Clinical Application. And this study is investigated to make sure of the necessity and additional symptoms in using Bojoongikgitang. The results are as follows : 1. It is regarded that the structure materials of Bojoongikgitang consist of Astragali Radix one jeon(錢) five poon(分), Ginseng Radix, Atractylodis Macrocephalae Rhizoma, Glycyrrhizae Radix one jeon for each, Citri Pericarpium, Angelicae Gigantis Radix five poon for each, Cimicifugae Rhizoma, Bupleuri Radix three poon for each. 2. The necessity symptoms in using Bojoongikgitang are a pale complexion, drowsy eyes(目無精光), vigorless, lethargy, sluggish talk. 3. The fittest prescriptions prior to the necessity symptoms in using Bojoongikgitang are Bojoongikgitang added Paeoniae Radix Alba, Scutellariae Radix in fever, exterior heat, mild fever, Bojoongikgitang added Ephedrae Radix, Tritici Fructus Levis, Aconiti Iateralis Preparata Radix in spontaneous sweating, spontaneous sweating by yang deficiency, Bojoongikgitang added Paeoniae Radix Alba, Scutellariae Radix in feeling the pulse like a flood, largeness and weakness, scatter and largeness, flood and largeness for diagnosis respectively. Bojoongikgitang Entering the heart channel by culturing the blood prescription in vexation, vexation and anxiety, Soongihwajoongtang in headache, DossiBojoongikgitang in rigor, Bojoongikgitang annexed Saengmaecsan in thirst, Daninsamtang or Jojoongikgitang in asthma, asthma by congestion of the upwardness, Eeegongsan in light eating, eschewing food, losing one's appetite, Ikweeseungyangtang in deficiency failing to control blood and blood collapsey. 4. To treat a functional disease is superior to organic one in using Bojoongikgitang.

• Animal Bioscience
• /
• v.37 no.4
• /
• pp.576-590
• /
• 2024

Objective: The objective of this study was to identify genes associated with 305-day milk yield (MY) and fat yield (FY) that also influence the adaptability of the Thai multibreed dairy cattle population to tropical conditions. Methods: A total of 75,776 imputed and actual single nucleotide polymorphisms (SNPs) from 2,661 animals were used to identify genomic regions associated with MY and FY using the single-step genomic best linear unbiased predictions. Fixed effects included herd-year-season, breed regression, heterosis regression and calving age regression effects. Random effects were animal additive genetic and residual. Individual SNPs with a p-value smaller than 0.05 were selected for gene mapping, function analysis, and quantitative trait loci (QTL) annotation analysis. Results: A substantial number of QTLs associated with MY (9,334) and FY (8,977) were identified by integrating SNP genotypes and QTL annotations. Notably, we discovered 17 annotated QTLs within the health and exterior QTL classes, corresponding to nine unique genes. Among these genes, Rho GTPase activating protein 15 (ARHGAP15) and catenin alpha 2 (CTNNA2) have previously been linked to physiological traits associated with tropical adaptation in various cattle breeds. Interestingly, these two genes also showed signs of positive selection, indicating their potential role in conferring tolerance to trypanosomiasis, a prevalent tropical disease. Conclusion: Our findings provide valuable insights into the genetic basis of MY and FY in the Thai multibreed dairy cattle population, shedding light on the underlying mechanisms of tropical adaptation. The identified genes represent promising targets for future breeding strategies aimed at improving milk and fat production while ensuring resilience to tropical challenges. This study significantly contributes to our understanding of the genetic factors influencing milk production and adaptability in dairy cattle, facilitating the development of sustainable genetic selection strategies and breeding programs in tropical environments.

• Journal of the Korean Wood Science and Technology
• /
• v.42 no.2
• /
• pp.163-171
• /
• 2014

Environmental issues about indoor air quality have been increased and focused on volatile organic compounds (VOCs) caused cancer, asthma, and skin disease. Reducing VOCs has been attempted in many different methods such as using environmentally friendly materials and air cleaner or purifier. Charcoal is well known material for absorbing VOCs. Therefore, carbonized board from medium density fiberboard has been developed. We assumed that the source of carbonized boards can be any type of wood-based panels. In this study, carbonized boards were manufactured from oriented strand board (OSB) at 400, 600, 800, and $1000^{\circ}C$. Each carbonized OSB (c-OSB) was evaluated and determined physiomechanical characteristics such as exterior defects, dimensional shrinkage, modulus of elasticity, and bending strength. No external defects were observed on c-OSBs at all carbonizing conditions. As carbonizing temperature increased, less porosity between carbonized wood fibers was observed by SEM analysis. The higher rate of dimensional shrinkage was observed on c-OSB at $1000^{\circ}C$ (66%) than c-OSB at 400, 600, and $800^{\circ}C$ (47%, 58%, and 63%, respectively). The densities of c-OSBs were lower than original OSB, but there was no significant different among the c-OSBs. The bending strength of c-OSB increased 1.58 MPa (c-OSB at $400^{\circ}C$) to 8.03 MPa (c-OSB at $1000^{\circ}C$) as carbonization temperature increased. Carbonization temperature above $800^{\circ}C$ yielded higher bonding strength than that of gypsum board (4.6 MPa). In conclusion, c-OSB may be used in sealing and wall for decorating purpose without additional artwork compare to c-MDF which has smooth surface.

• Journal of Sasang Constitutional Medicine
• /
• v.18 no.2
• /
• pp.113-124
• /
• 2006

1. Objectives Sasang Constitutional Medicine is based on difference of Nature & Emotion(性情). The mind is held in high value to characteristics of each constitution's symptoms and prescriptions. This study is for psychotheraphy with Herbal medicines, Acupuncture and Moxibustion in Sasang Constitutional Medicine. 2. Methods Comparing with ${\ulcorner}$DongYi Soose Bowon Gabobon${\Ircorner}$ and ${\ulcorner}$DongYi Soose Bowon ShinChukbon${\Ircorner}$, we research the principle of human's organization which is connected with their talent and will. 3. Results and Conclusions (1) Sasang Constitutional Medicine consider human being more than disease in medical science. A Human being works up to take a reasonable in modern societies, as making friends, a practice of his daily life, mentality. (2) Psychotheraphy is as important as each constitution's symptoms and prescriptions on clinical medicine (3) Taeyangin should be moderate when expressing their sorrow & anger(哀怒) and take a step backward for a real purpose(恒心). (4) Soyangin should be moderate when expressing their sorrow & anger(哀怒) and watch the interior for a real purpose(恒心). (5) Taeumin should be moderate when expressing their happiness & pleasantness(喜樂) and watch the exterior for a real purpose(恒心). (6) Soeumin should be moderate when expressing their happiness & pleasantness(喜樂) and go one step forward for a real purpose(恒心).

• Journal of Biomedical Engineering Research
• /
• v.31 no.5
• /
• pp.395-400
• /
• 2010

Hypertension is the chronic disease that the 16% of total population are suffering, and it needs to be studied to find alternative treatment because of the tolerance and side effect of medications that may bother some patients. in this paper, we verified practicality of implantable electrical stimulator that can readily change stimulus magnitude and frequency. And this device is possible to stimulate baroreflex or parasympathetic nerve. Therefore we performed in vitro tests and animal experiment for device's operating conditions. This device consist of implantable electrical stimulator and extracorporeal control/monitoring system. Stimulator was designed to make 1Hz~100Hz pulses and it can change continuous or periodic pulse train type. And this device can control stimulator's function and monitor stimulator's status and patients' blood pressure at exterior of body using ZigBee module as wireless telecommunication. We verified that stimulator have error rate under 5% at 50mm depth of organs and, stimulator makes high-efficiency energy with closer position of two electrodes. Also we can confirm the performance of device that decreasing blood pressure and heart rate of a rat by electrical stimulation.