• 통합자연과학논문집
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• 제15권3호
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• pp.123-129
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• 2022

Schwann cells play a critical role for myelination in peripheral nerve system. It also plays an important role in nerve protection and regeneration. In peripheral nerve damage, regeneration is induced by the migration and proliferation of Schwann cells which were promoted by suppressing the oxidative stress. In this study, Human placental extract was prepared by homogenization and estimated its efficacy in RSC96 cells. Placental extract exhibited a protective effect against hydrogen peroxide-induced oxidative stress in RSC96 cells, confirmed by MTT assay. Furthermore, placental extract decreased intracellular ROS against oxidative stress, confirmed by DCFH-DA assay. Autophagy was visualized with Cyto-ID staining to confirm the autophagy activity of placental extracts. The activity of autophagy was confirmed by immunoblot analysis of autophagy flux-associated proteins such as LC3 conversion and SQSTM1 degradation. Thus, we confirmed the antioxidant effect of placental extract to protect RSC96 cells from oxidative stress, and observed that it activated autophagy and restored autophagy flux.

• International journal of advanced smart convergence
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• 제13권1호
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• pp.180-184
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• 2024

Since COVID-19, many foreign tourists have visited Korea for medical tourism. When statistical data were checked from 2022, after COVID-19, the number of foreign patients visiting Korea for two years was 24.8 million, an increase of 70.1% from 2020. It was confirmed that it has achieved a 50% level compared to 2019 (Statistics Office, 2023). Therefore, to create a development plan by linking medical tourism and wellness tourism, the purpose of this study is to find the link between medical tourism and wellness tourism as big data and present a development plan. In this research method, medical tourism, and wellness tourism for two years from 2022 to 2023 from the post-COVID period as big data are set as central keywords to compare text data to find common points. When analyzing wellness tourism and medical tourism, it was confirmed that most wellness tourism had a greater frequency than medical tourism. This confirmed that wellness tourism occupies a larger pie than medical tourism. As a result, when checking the word frequency, it was confirmed that wellness tourism and medical tourism share a lot as complex tourism products, and when checking 2-gram, to attract many medical tourists, it is necessary to combine medical tourism clusters and wellness tourism according to each other's characteristics among local governments.

• 대한화장품학회지
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• 제48권3호
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• pp.213-223
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• 2022

본 연구에서는 과도한 산화 스트레스에 따른 각종 염증 질환과 피부 노화를 예방하기 위해 수영 지상부(aerial parts of Rumex acetosa L.) 추출물의 항염증, 항산화 효과를 확인하였다. ABTS assay를 시행한 결과 농도 의존적으로 radical 소거능이 증가함을 확인하였다. 활성산소종(reactive oxygen species, ROS) 억제능은 DCF-DA assay를 통하여 확인하였고, 농도 의존적인 ROS 생성억제를 확인하였다. ROS에 따른 세포 핵 손상 억제 효과는 DAPI staining을 통하여 확인하였다. 또한 iNOS, COX-2의 mRNA 발현 수준은 qPCR을 통하여 농도 의존적으로 억제함을 확인하였다. iNOS, COX-2의 단백질 수준을 western blotting을 통해 확인한 결과, iNOS는 모든 농도에서 유의하게 감소하였으며, COX-2는 800 ㎍/mL에서 유의하게 감소하였다. iNOS에 의해 생성된 NO의 생성 억제 효과는 NO assay로 확인하였으며 농도 의존적으로 NO가 감소하였다. 또한, MAPKs 신호전달 경로 중 ERK와 JNK의 인산화를 억제하였다. 따라서 Rumex acetosa L.은 MAPKs 경로를 통한 항염증 효과와 항산화 효과를 보여 항염증 및 항산화 화장품 원료로 사용될 수 있는 가능성이 있다.

• 한국태양에너지학회 논문집
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• 제33권6호
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• pp.47-53
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• 2013

In order to reduce the energy consumption of the building, much effort is being made. The problems are that excessive solar radiation in summer and the heat loss in winter by the increase of window area. To prevent this problems, government limited the window area ratio or the performance of windows in new buildings. In order to reduce energy consumption of the existing buildings, the window film insulation is spotlight because the window film insulation was simple to installation. This study confirmed the performance of the window film insulation and affect to heating & cooling load of buildings. The impact of the window film insulation coating was confirmed by experiment. And this study confirmed the annual heating & cooling load by simulation. As a results, the surface temperature of coated window was higher than the surface temperature of existing window. The window film insulation was increased surface temperature of window. And this study confirmed that the increased surface temperature was slightly affected the room air temperature through experiment of the insulation box. The results of the heating and cooling load by simulation, this study confirmed that the case of coated window film insulation decreased cooling load in summer and increased heating load in winter. Also the annual total heating & cooling load was increased a little in the case of coated the window film insulation.

• Journal of Korea Trade
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• 제26권7호
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• pp.185-202
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• 2022

Purpose - As overseas direct purchase transactions using e-commerce increase, the scale and scope of international trade are diversified, and the transaction volume using online platforms in e-commerce is increasing. The e-commerce market share will become more important because it is not only a medium connecting B2C, but also because it will expand the scope of trade. This study aims to reveal the factors that influence purchase intention according to Korean-Chinese consumers in e-commerce. In addition, the study has comprehensively confirmed the influence between each factor in the e-commerce environment by integrating and analyzing the characteristic factors of online information sources and platforms in one structural equation. Finally, the study confirmed that there is a significant difference in the influence relationship between Korean and Chinese consumers. Through this, the study will contribute to content production in the e-commerce market according to the target market and the expansion of the mutual entry of Korea and China. Design/methodology - This study aims to confirm the mediating effect of the details of the online information source characteristics and platform characteristics when the perceived quality affects purchase intention. It is confirmed that the factors affecting Korean and Chinese consumers differ. Findings - It was confirmed that differences exist according to the group of Korean or Chinese consumers for the entire research model. In the case of Korean consumers, the mediating factors when perceived quality affects purchase intention are expertise, reliability, entertainment, informativity, and convenience; in the case of Chinese consumers, the factors are expertise and informativity. Originality/value - This study proved that Korean and Chinese consumers cannot be regarded as having the same characteristics, and therefore, strategies aimed at each e-commerce market should be differentiated. In addition, although previous studies on online information sources and platform characteristics were not integrated, this study confirmed a significant influence relationship among the factors that could affect purchase intention in the actual e-commerce environment.

• 한국태양에너지학회 논문집
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• 제35권1호
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• pp.61-68
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• 2015

The advanced counties effort to the supplement of the zero energy buildings for the global building energy saving. In the middle of the development of passive technology, the government has to effort to the energy saving of buildings by enhanced performance of the window thermal insulation. By the method of enhanced performance of window thermal insulation, the use of vacuum double glazing saves the energy consumption in building. This glazing has low U-value(heat transmission coefficient) than normal double glazing. The vacuum glazing enhanced thermal insulation performance by vacuum space of between the glass and glass. For this vacuum glazing, pillar maintain the space between glass and glass. But this structure cause the raising the heat transmission coefficient in pillar approaching glass. This study confirmed the U-value by the test method of thermal resistance for windows and doors. Also this study confirmed the variation of heat transmission coefficient by the structure of vacuum glazing. And this study measured the surface temperature of the vacuum glazing about pillar approaching glass and vacuum space in cool chamber and hot box. That result, this study confirmed U-value of $0.422W/m^2{\cdot}K$ of vacuum glazing. Also this study confirmed U-value of $0.300{\sim}0.422W/m^2{\cdot}K$ by various the structure of vacuum glazing. And this study confirmed the heat flow in pillar approaching glass.

• 보존과학회지
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• 제38권4호
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• pp.314-326
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• 2022

Investigation of conservation status, optical survey, infrared thermography, and ultrasonic examination were performed on Avalokitesvara Bodhisattva mural and Buddhist Monk Bodhidharma mural to determine the conservation status and physical properties. As a result of investigation of conservation status, the types of damage are largely divided into the wall and finishing layer damage, painting layer degradation, damage due to restoration materials, stains and contamination, and biological damage. As a result of the optical survey, drawing, stains, and repainted site were confirmed. Result of the infrared thermography, the delamination of the finishing layer was confirmed, and some locations and shapes of the wooden lath inside the wall were identified. The result of the 3D scanning, the deviation, and the separation of the wall was confirmed. As a result of ultrasonic examination, it was confirmed that the physical properties of the mural were identified and the ultrasonic speed was relatively low due to physical damage such as delamination and exfoliation of the finishing layer and cracking. Ultrasonic speed values were also high in some wall cracks or delamination, and it was confirmed by the infrared thermography results that the wooden lath inside the wall was located in those parts. It was possible to understand that the wooden lath inside the walls affects the ultrasonic speed during the ultrasonic examination. Therefore, management through periodic inspection of the relevant elements is necessary, and a countermeasure for damage that may occur in the future should be prepared along with intensive monitoring of the major damage identified in this diagnosis result.

• 동국한의학연구소논문집
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• 제5권
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• pp.167-186
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• 1996

This study aimed to evaluate the protective effect of the MeoH extract of Ikhwangsan against galactosamine-induced hepatotoxicity. In the experiments, after treated with Ikhwangsan methanol extract to the rats for 15days and then induced hepatotoxicity with galactosamine for 2days. Then content of glutathione, level of lipid peroxide and activity of GOT GPT in the hepatic tissue, activity of GOT GPT ${\gamma}$-GTP ALP and ratio albumin/globulin in serum were measured. The results were obtained as followed : 1. The content of hepatic glutathione was significantly reduced by galactosamine. The test group which have been pre-treated by Ikhwangsan was confirmed considerably increased. 2. The level of hepatic lipid peroxide was increased by galactosamine. The test group which have been pre-treated by Ikhwangsan was confirmed considerably reduced. 3. The activity of GOT GPT in the hepatic tissue was significantly constrained by galactisamine. The test group which have been pre-treated by Ikhwangsan was confirmed considerably increased. 4. The activity of GOT GPT in serum was increased by galactosamine. The test group which have been pre-treated by Ikhwangsan was confirmed considerably reduced. 5. The activity of ${\gamma}$-GTP in serum was increased by galactosamine. The test group which have been pre-treated by Ikhwangsan was reduced. 6. The activity of ALP in serum was increased by galactosamine. The test group which have been pre-treated by Ikhwangsan was confirmed considerably reduced. 7. The ratio albumin/globulin in serum was reduced by galactosamine. The test group which have been pre-treated by Ikhwangsan was increased.

• 한국전기전자재료학회논문지
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• 제28권6호
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• pp.390-395
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• 2015

Molded insulation materials are widely used from large electric power transformer apparatus to small electrical machinery and apparatus. In this study, by adding MgO with the average particle of several tens nm and the excellent thermal conductivity into molding material, we improved the problem of insulation breakdown strength decrease according to rising temperature in overload or in bad environmental condition. We confirmed the life evaluation by using the insulation breakdown and inverse involution to investigate the electrical characteristics of nano-composites materials. By using a scanning electron microscope, it is confirmed that MgO power with the average particle size of several tens nm is distributed and the filler particles is uniformly distributed in the cross section of specimens. And it is confirmed that the insulation breakdown strength of Virgin specimens is rapidly decreased at the high temperature area. But it is confirmed that the insulation breakdown strength of specimens added MgO slow decreased by thermal properties in the high temperature area improved by the contribution of the heat radiation of MgO and the suppression of tree. The results of life prediction using inverse involution, it is confirmed that the life of nano-composites is improved by contribution of MgO according to the predicted insulation breakdown strength after 10 years of specimens added 5.0 wt% of MgO is increased about 2.9 times at RT, and 4.9 times at $100^{\circ}C$ than Virgin specimen, respectively.

• 무역상무연구
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• 제57권
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• pp.243-282
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• 2013

This study aims to develop the research model about the factors that have impact on uTradeHub users' acceptance and resistance to innovation. The followings show the research hypotheses and the results of test. i) The result of H1 empirical analysis confirmed that relative advantage and task adaptedness of e-Trade have more impact on acceptance of innovation than on resistance to it. And also perceived risk and complicity of e-Trade have more impact on resistance of innovation than on acceptance to it. ii) The result of H2 analysis confirmed that the characteristics of foreign trading companies (support by CEO and IT infra maturity) has more impact on acceptance of innovation than on resistance to it. iii) The result of H3 analysis confirmed that characteristics of uTradeHub user' resistance has more impact on resistance of innovation than on acceptance to it. And also, it was confirmed that acceptance of innovation has more impact on the diffusion of e-Trade than resistance to innovation. iv) The result of H4 analysis confirmed that the difference of the degree and factors that has impact on the user's resistance and acceptance by adoption stage of e-Trade. This study has significance in that it arranges the concept and stages of e-Trade systematically and, unlike other studies, it goes beyond the acceptance and diffusion of e-Trade to the inclusion of resistance together in the model.