• Title/Summary/Keyword: The Next generation

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The Estimation of Selection Response for Growth Traits in 31-month Old of Pacific abalone, Haliotis discus hannai (31개월령 북방전복, Haliotis discus hannai의 성장형질에 대한 선발반응 추정)

  • Park, Jong-Won;Park, Choul-Ji;Lee, Jeong-Ho;Noh, Jae-Koo;Kim, Hyun-Chul;Hwang, In-Joon;Kim, Sung-Yeon
    • The Korean Journal of Malacology
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    • v.28 no.4
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    • pp.335-342
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    • 2012
  • This study was conducted to estimation the selection response for growth-related traits in 31-month old of Pacific abalone, Haliotis discus hannai were born in 2008. In overall mean of surveyed traits and standard deviation showed $76.31{\pm}7.247$ mm of shell length, $49.48{\pm}5.307$ mm of shell width and $40.96{\pm}6.80$ g of total weight. The effect of sex and maturity were statistically significant in all traits include out a condition factor (p < 0.01). And In effect of sex, female were higher than male in all traits excepting condition factor, significantly. In correlation between breeding value and phenotypic value by each traits, showed rank correlation coefficient and simple correlation coefficient, which represented low positive correlation. A hopeful genetic improvement to the next generation showed 6.96 mm of shell length, 4.47 mm of shel width and 12.93 g of total weight. Therefor, It is considered that if considering properly selection intensity and selection ratio, efficient improvement could be made.

Studies on Cu Dual-damascene Processes for Fabrication of Sub-0.2${\mu}m$ Multi-level Interconnects (Sub-0.2${\mu}m$ 다층 금속배선 제작을 위한 Cu Dual-dmascene공정 연구)

  • Chae, Yeon-Sik;Kim, Dong-Il;Youn, Kwan-Ki;Kim, Il-Hyeong;Rhee, Jin-Koo;Park, Jang-Hwan
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.36D no.12
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    • pp.37-42
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    • 1999
  • In this paper, some of main processes for the next generation integrated circuits, such as Cu damascene process using CMP, electron beam lithography, $SiO_2$ CVD and RIE, Ti/Cu-CVD were carried cut and then, two level Cu interconnects were accomplished. In the results of CMP unit processes, a 4,635 ${\AA}$/min of removal rate, a selectivity of Cu : $SiO_2$ of 150:1, a uniformity of 4.0% are obtained under process conditions of a head pressure of 4 PSI, table and head speed of 25rpm, a oscillation distance of 40 mm, and a slurry flow rate of 40 ml/min. Also 0.18 ${\mu}m\;SiO_2$ via-line patterns are fabricated using 1000 ${\mu}C/cm^2$ dose, 6 minute and 30 second development time and 1 minute and 30 second etching time. And finally sub-0.2 ${\mu}$ twolevel metal interconnects using the developed processes were fabricated and the problems of multilevel interconnects are discussed.

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CNVDAT: A Copy Number Variation Detection and Analysis Tool for Next-generation Sequencing Data (CNVDAT : 차세대 시퀀싱 데이터를 위한 유전체 단위 반복 변이 검출 및 분석 도구)

  • Kang, Inho;Kong, Jinhwa;Shin, JaeMoon;Lee, UnJoo;Yoon, Jeehee
    • Journal of KIISE:Databases
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    • v.41 no.4
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    • pp.249-255
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    • 2014
  • Copy number variations(CNVs) are a recently recognized class of human structural variations and are associated with a variety of human diseases, including cancer. To find important cancer genes, researchers identify novel CNVs in patients with a particular cancer and analyze large amounts of genomic and clinical data. We present a tool called CNVDAT which is able to detect CNVs from NGS data and systematically analyze the genomic and clinical data associated with variations. CNVDAT consists of two modules, CNV Detection Engine and Sequence Analyser. CNV Detection Engine extracts CNVs by using the multi-resolution system of scale-space filtering, enabling the detection of the types and the exact locations of CNVs of all sizes even when the coverage level of read data is low. Sequence Analyser is a user-friendly program to view and compare variation regions between tumor and matched normal samples. It also provides a complete analysis function of refGene and OMIM data and makes it possible to discover CNV-gene-phenotype relationships. CNVDAT source code is freely available from http://dblab.hallym.ac.kr/CNVDAT/.

The Biological Functions of Plant Long Noncoding RNAs (식물의 긴비암호화 RNA들의 생물학적 기능)

  • Kim, Jee Hye;Heo, Jae Bok
    • Journal of Life Science
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    • v.26 no.9
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    • pp.1097-1104
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    • 2016
  • With the development of next generation sequencing (NGS), large numbers of transcriptional molecules have been discovered. Most transcripts are non -coding RNAs (ncRNAs). Among them, long non-coding RNAs (lncRNAs) with more than 200 nucleotides represent functional RNA molecule that will not be translated into protein. In plants, lncRNAs are transcribed by RNA polymerase II (Pol II) or Pol III, Pol VI and Pol V. After transcription of these lncRNAs, more RNA processing mechanisms such as splicing and polyadenylation occurs. The expression of plant lncRNAs is very low and is tissue specific. However, these lncRNAs are strongly induced by specific external stimuli. Because different external stimuli including environmental stresses induce a large number of plant lncRNAs, these lncRNAs have been gradually considered as new regulatory factors of various biological and development processes such as epigenetic repression, chromatin modification, target mimicry, photomorphogenesis, protein relocalization, environmental stress response, pathogen infection in plants. Moreover, some lncRNAs act as precursor of short RNAs. Although a large number of lncRNAs have been predicted and identified in plants, our current understanding of the biological function of these lncRNAs is still limited and their detailed regulatory mechanisms should be elucidated continuously. Here, we reviewed the biogenesis and regulation mechanisms of lncRNAs and summarized the molecular functions unraveled in plants.

The Header Compression Scheme for Real-Time Multimedia Service Data in All IP Network (All IP 네트워크에서 실시간 멀티미디어 서비스 데이터를 위한 헤더 압축 기술)

  • Choi, Sang-Ho;Ho, Kwang-Chun;Kim, Yung-Kwon
    • Journal of IKEEE
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    • v.5 no.1 s.8
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    • pp.8-15
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    • 2001
  • This paper remarks IETF based requirements for IP/UDP/RTP header compression issued in 3GPP2 All IP Ad Hoc Meeting and protocol stacks of the next generation mobile station. All IP Network, for real time application such as Voice over IP (VoIP) multimedia services based on 3GPP2 3G cdma2000. Frames for various protocols expected in the All IP network Mobile Station (MS) are explained with several figures including the bit-for-bit notation of header format based on IETF draft of Robust Header Compression Working Group (ROHC). Especially, this paper includes problems of IS-707 Radio Link Protocol (RLP) for header compression which will be expected to modify in All IP network MS's medium access layer to accommodate real time packet data service[1]. And also, since PPP has also many problems in header compression and mobility aspects in MS protocol stacks for 3G cdma2000 packet data network based on Mobile IP (PN-4286)[2], we introduce the problem of solution for header compression of PPP. Finally. we suggest the guidelines for All IP network MS header compression about expected protocol stacks, radio resource efficiency and performance.

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A Study on Applicability of Hydrofluoroethers as CFC-Alternative Cleaning Agents (CFC 대체 산업세정제로의 HFEs의 적용가능성 연구)

  • Min, Hye-Jin;Shin, Jin-Ho;Bae, Jae-Heum;Kim, Hong-Gon;Lee, Hyun-Joo
    • Clean Technology
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    • v.14 no.3
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    • pp.184-192
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    • 2008
  • Fluoride-type cleaning agents such as 2,2,2-trifluoroethanol (TFEA) and hydrofluoroethers (HFEs) do not destroy ozone in the stratosphere and have low global warming potential compared to hydrofluorocarbons(HFCs) and hydrochlorofluorocarbons (HCFCs). Especially, HFEs which have no flash point are paid attention as next generation type of cleaning agents for chlorofluorocarbons (CFCs) since they are safe in handling and have excellent penetration ability compared to hydrocarbon cleaning agents with low flash point. Here, the physical properties and cleaning abilities of fluoride-type cleaning agents such as TFEA, HFE-7100, HFE-7200, HFE-476mec, HFE-449mec-f, AE-3000 and AE-3100E and silicide-type cleaning agents such as trifluoroetoxytrimethylsilane (TFES) and hexamethyldisilazane (HMDS) were measured and compared with those of ozone destruction substances such as CFC-113 and 1,1,1-trichloroethane. They were also compared with toxic methylene chloride (MC) and isopropyl alcohol (IPA) which are now being used as an alternative cleaning agents. As a result, TFEA and HFEs had lower cleaning ability for removal of various soils compared to chloride-type cleaning agents, but they showed excellent cleaning ability fur fluoride-type soils. TFES and HMDS also showed excellent cleaning ability for silicide-type soils.

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Visible Light Communication Based Wide Range Indoor Fine Particulate Matter Monitoring System (가시광통신 기반 광역 실내 초미세먼지 모니터링 시스템)

  • Shakil, Sejan Mohammad Abrar;An, Jinyoung;Han, Daehyun;Chung, Wan-Young
    • Journal of the Institute of Convergence Signal Processing
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    • v.20 no.1
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    • pp.16-23
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    • 2019
  • Fine particulate matter known as PM 2.5 refers to the atmospheric particulate matter that has a diameter less than 2.5 micrometer identified as dangerous element for human health and its concentration can provide us a clear picture about air dust concentration. Humans stay indoor almost 90% of their life time and also there is no official indoor dust concentration data, so our study is focused on measuring the indoor air quality. Indoor dust data monitoring is very important in hospital environments beside that other places can also be considered for monitoring like classrooms, cements factories, computer server rooms, petrochemical storage etc. In this paper, visible light communication system is proposed by Manchester encoding technique for electromagnetic interference (EMI)-free indoor dust monitoring. Important indoor environment information like dust concentration is transferred by visible light channel in wide range. An average voltage-tracking technique is utilized for robust light detection to eliminate ambient light and low-frequency noise. The incoming light is recognized by a photo diode and are simultaneously processed by a receiver micro-controller. We can monitor indoor air quality in real-time and can take necessary action according to the result.

VANET Privacy Assurance Architecture Design (VANET 프라이버시 보장 아키텍처 설계)

  • Park, Su-min;Hong, Man-pyo;Shon, Tae-shik;Kwak, Jin
    • Journal of Internet Computing and Services
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    • v.17 no.6
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    • pp.81-91
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    • 2016
  • VANET is one of the most developed technologies many people have considered a technology for the next generation. It basically utilizes the wireless technology and it can be used for measuring the speed of the vehicle, the location and even traffic control. With sharing those information, VANET can offer Cooperative ITS which can make a solution for a variety of traffic issues. In this way, safety for drivers, efficiency and mobility can be increased with VANET but data between vehicles or between vehicle and infrastructure are included with private information. Therefore alternatives are necessary to secure privacy. If there is no alternative for privacy, it can not only cause some problems about identification information but also it allows attackers to get location tracking and makes a target. Besides, people's lives or property can be dangerous because of sending wrong information or forgery. In addition to this, it is possible to be information stealing by attacker's impersonation or private information exposure through eavesdropping in communication environment. Therefore, in this paper we propose Privacy Assurance Architecture for VANET to ensure privacy from these threats.

Layered Double Hydroxide Nanoparticles for Bio-Imaging Applications (LDH 나노입자 기반의 바이오 이미징 소재)

  • Jin, Wenji;Ha, Seongjin;Lee, Dongki;Park, Dae-Hwan
    • Korean Chemical Engineering Research
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    • v.57 no.4
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    • pp.445-454
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    • 2019
  • Layered double hydroxides (LDHs) nanoparticles have emerged as novel nanomaterials for bio-imaging applications due to its unique layered structure, physicochemical properties, and good biocompatibility. Bio-imaging is one of the most important fields for medical applications in clinical diagnostics and therapeutics of various diseases. Enhanced diagnostic techniques are needed to realize new paradigm for next-generation personalized medicine through nanoscale materials. When nanotechnology is introduced into bio-imaging system, nanoparticle probes can endow imaging techniques with enhanced ability to obtain information about biological system at the molecular level. In this review, we summarize structural features of LDH nanoparticles with current issues of bio-imaging system. LDH nanoparticle probes are also discussed through in vitro as well as in vivo studies in various bio-imaging techniques including fluorescence imaging, magnetic resonance imaging (MRI), positron emission tomography (PET), and computed X-ray tomography (CT), which will have the potential in the development of the advanced nanoparticles with high sensitivity and selectivity.

SNP Markers Useful for the Selection of Yellow-fleshed Peach Cultivar (황육계 복숭아 품종 선발용 SNP 마커)

  • Kim, Se Hee;Kwon, Jung-hyun;Cho, Kang Hee;Shin, Il Sheob;Jun, Ji Hae;Cho, Sang-Yun
    • Korean Journal of Plant Resources
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    • v.34 no.5
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    • pp.443-450
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    • 2021
  • Peach flesh color is commercially important criteria for classification and has implications for nutritional quality. To breed new yellow-fleshed peach cultivar many cross seedlings and generations should be maintained. Therefore it is necessary to develop early selection molecular markers for screening cross seedlings and germplasm with economically important traits to increase breeding efficiency. For the comparison of transcription profiles in peach varieties with a different flesh color expression, two cDNA libraries were constructed. Differences in gene expression between yellow-fleshed peach cultivar, 'Changhowon Hwangdo' and white-fleshed peach cultivar, 'Mibaekdo' were analyzed by next-generation sequencing (NGS). Expressed sequence tag (EST) of clones from the two varieties was selected for nucleotide sequence determination and homology searches. Putative single nucleotide polymorphisms (SNPs) were screened from peach EST contigs by high resolution melting (HRM) analysis, SNP ID ppa002847m:cds and ppa002540m:cds displayed specific difference between 17 yellow-fleshed and 21 white-fleshed peach varieties. The SNP markers for distinguishing yellow and white fleshed peach varieties by HRM analysis offers the opportunity to use early selection. This SNP markers could be useful for marker assisted breeding and provide a good reference for relevant research on molecular mechanisms of color variation in peach varieties.