• Radiation Oncology Journal
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• 제37권1호
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• pp.1-12
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• 2019

Despite recent innovation in treatment techniques and subsequently improved outcomes, the majority of glioblastoma (GBL) have relapses, especially in locoregional areas. Local re-irradiation (re-RT) has been established as a feasible option for recurrent GBL of all ages with safety, tolerability, and effectiveness both in survival and quality of life regardless of fractionation schedule. To keep adverse effects under acceptable range, cumulative dose limit in equivalent dose at 2 Gy fractions by the linear-quadratic model at α/β = 2 for normal brain tissue (EQD2) with narrow margin should be observed and single/hypofractionated re-RT should be undertaken very carefully to recurrent tumor with large volume or adjacent to the brainstem. Promising outcome of re-operation (re-Op) plus re-RT (re-Op/RT) need to be validated and result from re-RT with temozolomide/bevacizumab (TMZ/BV) or new strategy is expected. Development of new-concept prognostic scoring or risk group is required to select patients properly and make use of predictive biomarkers such as O(6)-methylguanine-DNA methyltransferase (MGMT) promotor methylation that influence outcomes of re-RT, re-Op/RT, or re-RT with TMZ/BV.

• 기독교교육논총
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• 제63권
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• pp.13-37
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• 2020

중국 우한에서 발생한 코로나바이러스(COVID-19)의 전파력과 치사율에 주목한 WHO는 글로벌 비상사태를 선언했으나, 효과적인 치료제를 확보하지 못한 채 상황이 악화되자 팬데믹으로 상향 조정했다. 사회적 거리두기와 자가 격리 및 여행 제한에 따른 경제위기 때문에 자유무역 중심 세계 경제체제 붕괴와 세계화의 퇴조가 거론되고 있다. 팬데믹에 제대로 대처하지 못한 정치리더십이 도전받고, 사회는 비접촉과 부동성 문화로 급속히 전환 중이다. 교육 분야에서는 탈학교화라는 개념이 디지털 매체를 통해 물리적 공간에서 현실화하고 있다. 교회교육 역시 심각한 위기에 처했다. COVID-19 팬데믹 상황에서 교회들은 팬데믹에 관한 신앙 및 신한적 성찰, 온라인 예배와 체계적인 신앙교육, 그리고 비대면 중심의 목회까지 포괄하는 이른바 뉴노멀을 기대하고 있다. 포스트 코로나 시대에 교회교육은 급변하는 주변 상황에 부응해서 적극적으로 대안을 모색하면서 의미 있는 기독교적 가치에 초점을 맞춘 교육신학을 새롭게 재구성해야 한다. 아울러서 오프라인과 온라인을 결합한 모바일(또는 온라인) 교회학교를 운영하는 한편, 비대면과 면대면 학습을 혼용하는 학습방식(Blended Learning)을 도입하고, 교회학교와 홈스쿨링을 결합해서 교회와 가정이 교육의 책임을 분담할 필요가 있다.

• Journal of Chest Surgery
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• 제29권2호
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• pp.136-146
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• 1996

Studies on normal human embryos and on malformed human hearts have been two main sources of the information on the developmental cardiology, Recent advances in the biological technology has opened a new era and descriptive embryology is being shifted into dynamic developmental biology. In this review, we discuss the current understanding on the cardiac embryology relevant to clinical practices of pediatric cardiology. Classical cardiac embryology starts with understanding on five segments of a straight heart tube : the sinus venosus, the primitive atria, the embryonic left ventricle, the embryonic right ventricle and the truncus arteriosus. Key steps in the normal morphogenetic process are the complex spiral septation of ventriculoarterial junction and two jumping connections : between the embryonic right atrium and embryonic right ventricle, and between the embryonic left ventricle and the aorta. Only after these two steps are successfully completed, the third fetal stage tak s place, when myocardial growth and remodeling take place There are two outstanding progresses on the cardiac embryology during recent five-year period. One is immunohistochemical mapping of the conduction system in the developing heart and the other is the understanding on the neural crest cell migration followed by molecular detection of the microdeletion of chromosome 22. A balanced progress of classical morphological studies, modern biological technics and advanced clinical medicine is an urgent task for doctors and scientists dealing with children with sick hearts.

• 대한생식의학회:학술대회논문집
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• 대한불임학회 2003년도 제45차 추계학술대회
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• pp.21-30
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• 2003

As a result of the technological advance provided by intracytoplasmic sperm injection (ICSI) in 1992, the evaluation and treatment of the infertile male has changed significantly. Many men who were previously thought to be irreversibly infertile have the potential to initiate their own biologic pregnancy. However, not all men having impaired semen parameter are ideal candidates for ICSI for numerous reasons including a lack of addressing the underlying problem causing the male infertility, unknown genetic consequences, and cost-effectiveness issues. In this era of ICSI, the fundamental approach to the male with suspected subfertility is unchanged and is based on a history, physical examination, and focused laboratory testing. The urologist should approach the patient with an intent to identify remediable causes of subfertility given the specific clinical situation. For instance, should a gentleman have his varicocele repaired or vasectomy reversed, or should he proceed directly with ICSI? If no factors can be improved in a timely manner, then ICSI should be considered using the available sperm. Examples of recent advances include the diagnosis and treatment of ejaculatory duct obstruction, indications and techniques for performing testis biopsy, and technique for sperm harvesting. In addition, potential genetic causes of male subfertility should be diagnosed and discussed with the patient. Cystic fibrosis gene mutation, karyotype abnormallities, and Y-chromosome microdeletions all have recently been identified as causative for male infertility in otherwise phenotypically normal men. With recently evolved diagnostic and therapeutic techniques now available for the infertile couple, even the most severe male factor problems in patients previously considered irreversibly infertile are now potentially treatable. The physician should be aware of the availability and limitations of these new and exciting reproductive technologies because they will allow him to provide timely and more effective therapy for the infertile couple. An understanding of these advances by all physicians is important as we progress into the $21^{st}$ century

• 한국경제지리학회지
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• 제23권3호
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• pp.197-208
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• 2020

본 연구에서는 한국사회의 계층갈등의 지형을 규명하고 불평등의 전개양상에 대한 체계적인 분석을 통해 공감사회에 관한 틀을 마련함으로써 코로나 시대의 극복방안을 제시하고자 한다. 분석결과, 계층에 대한 객관적 차원뿐만 아니라 주관적 차원인 삶에 대한 만족도와 계층의식은 비례하며, 계층적 지위일치의 구성은 양극화를 보여준다. 왜곡된 분배구조와 사회가치에 의해 소득 및 자산격차가 심화되고 있으며 교육격차와 계층의 구조화로 사회이동의 가능성을 굴절시키고 있는 것이다. 이러한 문제는 기회균등이나 제도적 공정성만으로는 치유하기 어려우며, 문화적 가치체계에 대한 냉철한 진단과 과감한 개혁이 필요하다. 코로나 위기극복과정을 통해 과거로 회귀하는 것은 옳지 않으며 잘못된 의식과 관행을 바로 잡아 국가와 사회구성원의 정합성을 재정립해야 한다. 나이가 경제와 글로벌 및 디지털 차원의 혁신과정을 통해 국가발전보다 사회발전을 우선시하고 구성원의 삶 자체를 중시하는 뉴 노멀 시대의 대전환이 요구된다. 갈등해결의 지속성은 사회적 토대로서 공동체에 관한 연대의식에 달려 있으며, 사회구성원의 신뢰와 소통에 바탕을 두는 공감사회가 필요하기 때문이다.

• 문화기술의 융합
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• 제9권3호
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• pp.167-181
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• 2023

본 연구는 코로나 19 발생 후 여행 제재가 완화된 현재의 관광행태 변화를 분석하기 위해 소셜네트워크 분석프로그램인 TEXTOM을 활용하였다. 네이버, 구글, 다음이 제공하는 블로그, 카페, 뉴스 등을 대상으로 '국내여행', '해외여행' 키워드에 대한 데이터를 수집하였다. 사회적 거리두기가 해제된 2022년 4월~12월로 수집 기간을 정하였고, 코로나19 발생 이전인 2019년과 코로나19의 영향이 가장 심각했던 2020년은 각각 1년으로 하여 2022년과 비교 분석하였다. 텍스트 마이닝을 통하여 각각 총 80개의 핵심어를 추출하고 NetDraw를 사용하여 중심성분석을 하였다. 마지막으로 CONCOR분석을 통하여 상관관계가 있는 핵심어들을 4개로 군집화하였다. 연구결과, 2022년도의 관광행태는 코로나 발생 이전으로의 관광 회복, 각자가 선호하는 테마를 중심으로 여행의 세분화, 나라별 코로나 완화정책을 우선적으로 검색해 본 후 관광지를 선택하는 관광행태를 보인다. 코로나19 이후에 새롭게 도래하는 관광생태계에 대한 관광마케팅 전략과 관광상품 개발을 위한 기초자료를 제공할 것으로 기대한다.

• The Journal of Asian Finance, Economics and Business
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• 제8권4호
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• pp.581-590
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• 2021

The purpose of the research was to investigate the characteristics of technology users, their knowledge about the technology and whether that affected technology adoption, and, through the measurement utilitarian value as a mediator, to find out whether the behavior toward mobile payment technology adoption is considered most effective during the COVID-19 pandemic, especially at this research locus, Central Java Province, Indonesian Batik SME consumers. The research methodology was quantitative with data processing using Structural Equation Modeling (SEM) with the final sample of 294 respondents' answers. To the best of the researcher's knowledge, this was an initial attempt toward a holistic and integrative approach to explain the adoption of mobile payment in Indonesia with different consumer characteristics in each region of Indonesia and varying levels of knowledge about mobile payment applications. The results show that the utilitarian value as a mediating variable only affected the relationship between the characteristics of technology users and adoption behavior. The findings of this study suggest that the stronger the knowledge of technology users, the more influential the adoption behavior of the mobile payment technology for Indonesian Batik small-, and medium-sized enterprise (SME) consumers during the COVID-19 pandemic in the new normal era.

• International Journal of Internet, Broadcasting and Communication
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• 제14권2호
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• pp.225-230
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• 2022

The intelligent home network system integrates various devices in the home into one communication network to provide information sharing, control, and operation environment between devices. This intelligent home network system operates around a home server. Home appliances in the era of the 4th industrial revolution will have numerous home servers in logical areas as the intelligent home network in the home accelerates. Therefore, the need for systematic management of home servers is emerging. We propose an agent system for efficient intelligent smart home server management. The agent system monitors the home server and operating environment for home server management of the intelligent smart home network. By referring to this monitored information, the service module of the home server is managed, and the home server is dealt with whether it is normal or not. In addition, by referring to the information collected by the service agent created in the group management server while migrating the home server, it is possible to deal with integrated meter reading, crime prevention, and topics. And when a new service is applied to the home server, it is registered in the management server and distributed to the home server through the agent, so that the intelligent smart home network can be efficiently managed.

• 무역학회지
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• 제47권1호
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• pp.63-77
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• 2022

As customer needs for eco-friendly transportation services increase, strategies of major global shipping companies are being established to meet them. Even if logistics costs increase, more and more shippers are choosing shipping companies that fulfill their social responsibilities through decarbonization, and against this backdrop, global shipping companies want to strengthen corporate social responsiveness and reduce shipping environmental costs. In the post-corona era after COVID-19, it is necessary to review the latest Green Shipping management strategies of shipping companies emerging as a new normal for the shipping and logistics industries. This study aims to explore trends in the latest Green Shipping management strategies of global shipping companies pursuing environmental load suppression in the shipping and logistics fields. Among the previous studies, some studies analyzed the green shipping policies of major shipping countries, but they did not deal with the latest policies over time, and few previous study has conducted a fact-finding analysis on the latest Green Shipping management strategies of major shipping companies at the corporate level. This study attempted to analyze securities reports by major domestic and international shipping companies and to present the latest Green Shipping management strategies by shipping companies.

• Asian Journal of Business Environment
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• 제7권2호
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• pp.17-20
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• 2017

Purpose - This paper will go deep into the analysis of Korean Cultural industry development, and the result of the analysis shows that the cultural value of cultural product, competitive product lines and mature Market Mechanism are core competences of Korean Cultural industry. Research design, data, and methodology - This is a case study in the era of knowledge based economy, Cultural industry has become a new increasing point of economic development. Cultural industry, commonly regarded as an industry with high-ended value, is occupying more important role in economic development and social welfare promotion process. Results - Moreover the increasingly important role of cultural industry will hopefully help to promote industrial upgrading process and finally become a driving force for economic growth and technological innovation. During the process of cultural development, improving core competence of Cultural industry is a key consideration to help the development of Cultural industry in a positive way. Conclusions - From the study above, we find that in order to ensure sustainable development of Cultural industry, emphasis should be put on finding and improving core competence. Core competence of Korean Cultural industry is important and inspiring to the development of Chinese Cultural industry and regional integration in the East Asian area.