• 한국의사학회지
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• 제18권2호
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• pp.245-255
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• 2005

The researcher categorized the acupuncture methods mentioned in DongUiBoGam according to the form, and examined how to select and use the acupuncture points explained in the Acupuncture/Moxibustion prescription. By comparing the original text to the Acupuncture/Moxibustion prescriptions, it was established that the various acupuncture points in these Acupuncture/Moxibustion prescriptions all had individual meaning. Also, it showed that DongUiBoGam didn't indicate a particular acupuncture point but allowed a possibility for selection according to the patient's condition and the skill of the practitioner.

• 한국전통의학지
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• 제15권1호
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• pp.49-55
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• 2006

Objective: <千金方(Qianjinfang)> which documents a great amount of prescription of Acupuncture and moxibustion bikes an important role during the development of acupuncture and moxibustion. Thus, it have given rise us to the research-situation of Tang Dynasty China of previous period. This study was to outline the rules of choosing acupoints as well as the prescriptions of contemporary times in reference with <千金方(Qianjinfang)>, and to discuss the conception of acupuncture and moxibustion in <千金方(Qianjinfang)>. Method: Based on <千金方(Qianjinfang)>, the parameters were categorized to a certain scope, syndromes in different type were classified. Also numbers of acupoints, route of meridians locations, utilities of special acupoints even prescription methods were statistically analyzed in reference with <千金方(Qianjinfang)>. Results & Conclusion: Acupuncture prescription in <千金方(Qianjinfang)> was mostly presented by single acupoint and this was basic prescription of its rule of choosing acupoints. Choosing acupoint for the majority of various diseases started from choosing meridians with the disorder, but no rules for choosing acupoints was clear. There was basically various methods in choosing acupoints, but little were used by Biao-Ii meridian choosing method (表裏經配穴.) In the high frequency of use, wu-shu acupoints was higher used than other specific acupoints (特定穴). While wu-shu acupoints treated the major parts of the diseases, shu-mo acupoints were strictly used on system. Consequently : The theoretical basis originating the choosing rules of the acupoints and prescriptions was shown in <千金方(Qianjinfang)> as representative clinical reference, through which it was valuable to analyze the prescription rule and specificity of the acupoints.

• 한국한의학연구원논문집
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• 제18권1호
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• pp.25-34
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• 2012

Objective : This study was carried out with focus on written by Joh, Taek-seung (曺澤承) and Joh, Byeong-who(曺秉矦) in the relation of father and son in 1933. This book is a medical book including rare data, which has never been reported to academic circles all this while. Method : First, this study looked into the authors of this book and its history of publication. Further, this study analyzed the composition and contents of this book. Lastly, this study summed up the meaning of this book from the standpoint of medical history. Result : The authors were Confucian doctors who were active in the latter era of the Joseon Dynasty and also in the period of Japanese colonial rule. They lived in Haenam district of Jeonlanam-do, and cured its neighboring local residents while studying. They published the book of by putting together their own medical experiences. The authors suggested their remedial prescription according to gender and age whereas Zhang Zhongjing(張仲景) suggested the remedial prescription according to Six-Meridian Pattern Identification & Syndrome Differentiation(六經辨證). In addition, the authors of gave weight to the relationship with internal damage. Additionally, the authors not only thought much of the relationship between internal damage and external damage but also thought of the weakness and strength of the healthy qi, and the new and the old of a disease as an important clue to medical treatment. It seems that such contents was influenced by (東醫寶鑑). Conclusion : shows the results of the research on which was spontaneously conducted in Joseon.

• 동의생리병리학회지
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• 제21권1호
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• pp.209-213
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• 2007

In the recent, increased concern has been focused on the pharmacology and clinical utility of herbal extracts and derivatives as a drug or adjunct to chemotherapy and immunotherapy. Salicis Radicis Cortex, A decoction has been mainly used for improvement of ozena and a diuretic effect in oriental medicine, but there was no study on the molecular mechanism of Salicis Radicis Cortex as an immunomodulator. Here we investigated the role of the aqueous extract of Salicis Radicis Cortex in the expression of inflammatory mediators, surface molecule, and related receptors in vitro and in vivo. In murine macrophage RAW 264.7 cells and peritoneal macrophages of C57BL/6N mice, water extract of Salicis Radicis Cortex increased the production of secretary TNF-alpha and Nitric oxide, and the expression level of CD14, LPS co-receptor and CD86, co-stimulatory molecule compared to negative natural extract ex vivo. Moreover, i.p. injection of water extract of Salicis Radicis Cortex significantly increased the secretion level of IFN-gamma and TNF-alpha, IL-2, IL-4 and IL-5 in serum of mice in vivo. Taken together, these results suggest that Salicis Radicis Cortex may regulate the immune response by secreting Th1 and Th2 types of cytokines in vivo and the possibility of its as natural immunostimulator.

• 한국한의학연구원논문집
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• 제5권1호
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• pp.59-72
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• 1999

Vibrio are become prevailing if superficial temperature of ocean is raised and their activities of area are expanded and most of ocean creatures(fishes, oysters etc) are polluted with vibrio. The one who has taken these poluted fishes and aysters uncooked caused foodpoisoning and diarrhea from Vibrio. Frequencies of these diseases breakout is disposed in westsea shore of Korea. According to ancient and traditional Korean medical book -${\ulcorner}$Bangyak Happyeon${\lrcorner}$(Collection of Local Medicines, 1884) - and their single prescribes, we carried out experiment check the activities of natural medicinal effects on Vibrio parahemolyticus. The prescriptions of trial materials are processed from extraction boiling water and 80% methanol and followed freeze dried and adsorbed to every discs in dosage of 10mg. Gentamycin of 10mg were used for control. The result of compound prescription displayed special diseases in antimicrobial activities of boiling water and MeOH extraction compared with control. In compound prescription, extraction MeOH of Sashinhwan(clear zone : 17mm) presented extraordinaire antimicrobial activity. In single prescription, extraction of boiling water(clear zone : 16mm) and MeOH(clear zone : 18mm) of Fructus Chebulae presented extraordinaire antimicrobial activity. The MBC of Fructus Chebulae extracts was expressed in boiling water(1.28mg/ml) and MeOH(0.64mg/ml).

• 한국의사학회지
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• 제17권2호
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• pp.111-127
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• 2004

This paper is mainly on the rsearch of the prescriptions of "Sanbeon-bang(刪 繁方)". For the research of prescription, investigated "Sanbeon-bang" from the side of symptoms of a disease, number of drugstuffs, table of contents, drugstuffs and acupuncture and moxibustion. With these investigation, made out a few tables, and with these tables made an attempt to understand the whole prescriptions of "Sanbeon-bang". "Sanbeon-bang" is of rich contents in internal medicine. Among internal medicine, related to Oro-Yukgeuk-Chilsang(五勞-六極-七傷) was most abundant. So we can guess "Sanbeon-bang" was a medical book specialized in exhaustion syndromes. It also deals with the Samcho-syndromes, as investigate from medical comments, has the perfect system of prescription in relative. From the investigation of the combination of drugstuffs, ascertained that, the number of simple prescription composed of one drugstuff was 38, combinational prescription composed of two drugstuffs was 9, minor prescription composed of three to five drugstuffs was 47, midum prescription composed of six to ten drugstuffs was 95, major prescription composed of eleven to twenty drugstuffs was 45, and mixed prescription composed over twenty drugstuffs was 1. Mentionable unique prescriptions in internal use were the forms of keeping in mouth. In external use they were fumigants, suppositories, powdered medicines, spraying the granular medication into the nasal cavity and eyedrops. And were abundant in soft extract(ointment) and plaster. In addition, there were the recordings of 18 types of cellulitis, types of incurable cellulitis and curing an illness by a charm. By the way, when comparing "Sanbeon-bang" with "Cheongeum-bang", all of which was quoted a lot in "Oedaebiyo-bang", "Cheongeum-bang" rather took medical comments of "Sanbeon-bang" than prescription. Although there were some prescriptons in "Sanbeon-bang" at the same category, "Cheongeum-bang" took another prescriptions which are more complexed than those of "Sanbeon-bang". In the same way, when comparing "Cheongeum-bang" with "Sonjinin-Cheongeum-bang(孫眞人千金方)", which didn't go through the correction of GyojeongUiseoguk of Bug-Song goverment, "Cheongeum-bang" often didn't take the prescriptions of "Sonjinin-Cheongeum-bang". Hence we can guess, "Cheongeumyo-bang" may have added a lot of prescriptions when undergoing the correction of of GyojeongUiseoguk. The total number of species of drugstuffs in "Sanbeon-bang" from the investigation was 284. The plant drugs were 208 species, the animal were 31 species, the minerals were 19 species and the other were 26 species. The prescriptions related to acupuncture and moxibustion in "Sanbeon-bang" were only moxibustional prescriptions. Which appeared one time per exhaustion and steaming of bone syndrome, Oro-Yukgeuk-Chilsang and Samcho syndrome. Appeared six times in muscle syndromes. But I cannot imagine the original form of acupuncture and moxibustion in "Sanbeon-bang" for deficiency of data.

• 혜화의학회지
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• 제14권1호
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• pp.167-177
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• 2005

In oriental medicine, Ostericum koreanum Radix & Aralia contientalis Radix are frequently used materials for strenthing lumbar and knees. Bang-Yak-Hap-Pyun(方藥合編) is widely used for clinical herbal prescription book. In Bang-Yak-Hap-Pyun, Ostericum koreanum Radix is used 1.2g~6g. and Aralia contientalis Radix is used 1.6g~4.8g. The most important fact is that the prescription used Ostericum koreanum Radix & Aralia contientalis Radix at the same time is 11. The number of prescription Ostericum koreanum Radix & Aralia contientalis Radix in Bang-Yak-Hap-Pyun is total 41. 5 in sang-tong(上統), 22 in jung-tong(中統), 14 in ha-tong(下統). The group of mostly used disease is about low back pain, knee pain, C.V.A., facail palsy, commom cold, numbness. The ratio of Ostericum koreanum Radix in Bang-Yak-Hap-Pyun is 3.03%~15.63%. And the ratio of Aralia contientalis Radix is 3.57%~12.00%. The mostly quoted medical literature what prescription included Ostericum koreanum Radix & Aralia contientalis Radix in Bang-Yak-Hap-Pyun is Dong-Yi-Bo-Gam. Man-Byeong-Hoi-Choon, and Hwa-Je-Gook-Bang.

• 한국한의학연구원논문집
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• 제9권2호
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• pp.131-148
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• 2003

This study was performed to evaluate the acute oral toxicity of an oriental medical prescription for obesity treatment, SH21-B, in Sprague-Dawley rats and Beagle dogs. SH21-B was administered in rats at does of 0mg/kg, 2,000mg/kg, and 5,000mg/kg. And also SH21-B was administered in Beagle dogs at does of 150mg/kg, 300mg/kg, and 600mg/kg. The rats and dogs of both sexes were observed daily for 14 days after single oral administration. Two female rats, one administered at 2,000mg/kg and the other administered at 5,000mg/kg, died, but no dead animal was observed among male rats. Therefore LD50 in the female rat is observed to be 8,710mg/kg, and MLD(Minimum Lethal Dose) of the male rat is observed to be more than 5,000mg/kg. Among dogs, no dead animal was observed up to 600mg/kg and MLD is observed to be more than 600mg/kg.

• 한국의사학회지
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• 제24권1호
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• pp.97-110
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• 2011

Rhinitis, inflammation of the nasal cavity caused by the disease in our country that a recent trend is the rapidly increasing number of patients. It causes multiple complications and interfere with daily life and social life in case of being viewed as a mild cold. The rhinitis treatment for symptomatic therapy in modern medicine is staying because the situation is exposing the limitations. so traditional medicine is trying to find a solution but that is not easy. In modern medicine, rhinitis is defined as a set of histological lesions and clinical symptoms, but traditional medicine has developed in dealing with each symptoms in disease. The treatment that doesn't distinguish any treatment in growing numbers of patients does not seem to validate, because doctors treat without considering the difference of recognition. Looking at the symptoms for each, I found that each symptoms and causes are varied according to doctors and era. In spite of considering all of that in treatment, it was ignored or underestimated in modern medicine. Furthermore, in traditional medicine, they just conjugated certain period theory and only had limited treatment by a lack of integrated awareness about definition and mechanism. In addition, in case of mentioning about the causes of prescription in each medical books, there were not enough explain about pathological states. Therefore, these causes should be made to further the research about the validity, pathogenesis and treatment. We can see that theory could be established and modified by the accumulation of clinical experience, observations through classification by each of the causes, prescription and treatment. In traditional medicine simply does not pay attention only to nasal inflammation, such as the impact of Meridian and organs considered to have focused on the fundamental treatment. This increased immune resistance to the modern rhinitis patients may offer new therapeutic approaches. I hope this paper would be helpful to find the treatment with uncovered theory in modern medicine.

• 대한한의학방제학회지
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• 제19권1호
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• pp.23-34
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• 2011

Objectives : Yiemyo-San(二妙散) is a basic oriental medicinal prescription used in basically musculoskeletal pain. Way down to posterity, Yiemyo-San has been combined with various prescriptions to treat a variety of diseases. the purpose of In this study is to investigate indications and etiology of indication using Yiemyo-San. Methodes : For prescriptions combining Yiemyo-San in Dongyeubogam(東醫寶鑑), the name of prescriptions, configuration herbs and indication were investigated and prescriptions were classified according to etiology of indication. Results : the numbers of prescriptions combining Yiemyo-San in Dongyeubogam were 45. Yiemyo-San was used frequently in musculoskeletal disease such as beriberi, amyotrophy, gout and arthritis(36%). In addition, it was applied to an internal diseases, ENT diseases and headache. it was used frequently in pathological condition due to supyeol(濕熱)(45%). Yiemyo-San was combined with various prescriptions as a primary prescription at 51% and as a secondary prescription at 49%. Conclusions : When Yiemyo-San is combined with other prescription, it may be used in various disease as well as musculoskeletal disease due to supyeol. combined with various prescriptions as a primary prescription at 51% and as a secondary prescription at 49%. Conclusions : When Yiemyo-San is combined with other prescription, it may be used in various disease as well as musculoskeletal disease due to supyeol.