• Journal of information and communication convergence engineering
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• v.4 no.4
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• pp.141-146
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• 2006

In these days, wireless data services are becoming ubiquitous in our daily life because they offers several fundamental benefits including user mobility, rapid installation, flexibility, and scalability. Moreover, the requests for various multimedia services and the Quality of Service (QoS) support have been one of key issues in wireless data communications. Therefore the research relative to Medium Access Control (MAC) has been progressing rapidly. Especially a number of QoS-aware MAC schemes have been introduced to extend the legacy IEEE 802.11 MAC protocol which has not guaranteed any service differentiation. However, none of those schemes fulfill both QoS features and channel efficiency although these support the service differentiation based on priority. Therefore this paper studies a novel MAC scheme, referred to as Enhanced Distributed Coordination Function with Network Adaptation (EDCF-NA), for enhancements of both QoS and medium efficiency. It uses a smart factor denoted by ACK rate and Network Load Threshold (TH). In this paper, we study how the value of TH has effect on MAC performance and how the use of optimal TH pair improves the overall MAC performance in terms of the QoS, channel utilization, collision rate, and fairness. In addition, we evaluate and compare both the performance of EDCF-NA depending on several pairs of TH and the achievement of various MAC protocols through simulations by using Network Simulator-2 (NS-2).

• Interaction and multiscale mechanics
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• v.2 no.4
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• pp.333-352
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• 2009

We introduce a radial basis collocation method to solve axially moving beam problems which involve $2^{nd}$ order differentiation in time and $4^{th}$ order differentiation in space. The discrete equation is constructed based on the strong form of the governing equation. The employment of multiquadrics radial basis function allows approximation of higher order derivatives in the strong form. Unlike the other approximation functions used in the meshfree methods, such as the moving least-squares approximation, $4^{th}$ order derivative of multiquadrics radial basis function is straightforward. We also show that the standard weighted boundary collocation approach for imposition of boundary conditions in static problems yields significant errors in the transient problems. This inaccuracy in dynamic problems can be corrected by a statically condensed semi-discrete equation resulting from an exact imposition of boundary conditions. The effectiveness of this approach is examined in the numerical examples.

• The Korean Journal of Zoology
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• v.36 no.2
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• pp.209-222
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• 1993

The present study attempts to explore the first appearance 8nd subsequent development of %cosine hvdroxvlase (TH)-containing neurons in the rat brain from embryonic day (E) 10.5 to the neonate. To increase the senti노ivity and resolution power, a double bridge peroxidase-anti-peroxidase technique was employed for cellular localization of TH. In situ hybridization histochemistw with synthetic TH oligomer (30-mer) codinB TH was also used to detect TH mRNA. TH-containing neurons were first detected at E11.5 in the intermediate zone of prosencepha1on and mesencephalon. At this stage, TH-immunoreactive neurons were small, ovoid bee and emitted their fibres into their immediate surroundings. From this stage, TH-immunoreactive neurons increased in their number and underwent migration and cell differentiation. At E15.5, the distribution pattern of the maior groups of TH neurons was similar to that of adult catecholaminergic groups, and at E19.5 the external laver of median eminence showed TH-immunoreactive processes.

• Clinical and Experimental Pediatrics
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• v.48 no.1
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• pp.6-12
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• 2005

In the last few years, a spectrum of dendritic cells(DCs), including toll like receptors(TLRs), might play a critical role in regulating allergy and asthma. DC plays a central role in initiating immune responses, linking innate and adaptive responses to pathogen. Human peripheral blood has three non-overlapping dendritic subset that expressed various 11 TLRs. These dendritic subsets and TLR contribute significant polarizing influences on T helper differentiation, but how this comes about is less clear. A better understanding of DC immunobiology may lead to the comprehension of allergy pathophysiology to prevent early stage allergic march.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.11
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• pp.6756-6766
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• 2014

The aim of this study was to validate the influence from academic stress caused by the achievement pressure of their parents and the adjustment effect of self-differentiation. The data was collected from 257 students from the 19th of May, 2014 to the 30th of May, 2014 for freshmen and sophomores of a college in the Kyoungbook region to validate the study. The SPSS/PC 18.0 program was used for the statistical analysis. Hierarchical multiple regression analysis revealed more less influence of academic stress caused by the achievement pressure((${\beta}=.111$, p<0.05) of their parents but there was no reasonable value in validating the adjustment effect to reduce the academic stress by self-differentiation, i.e., it should be a non-linear and complex effect rather than a simple linear relationship for self-differentiation.

• Journal of Korean Home Economics Education Association
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• v.9 no.2
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• pp.17-30
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• 1997

Purpose of this study is to analyze the validity of textbook content on practical arts for the 6th curriculum, to grasp the content problems and to propose the strategy of reformation to be satisfied with consumer better than supplier. The data collected from 196 elemantary school teachers who lived in Gyungsang-namdo and analized by SPSS/PC(sup)+ package program. The statistical methods used for analysis were frequency, descriptives, validity, t-test, oneway ANOVA. The major findings can be summarised as follows： 1. The textbooks on practical arts for 3rd, 4th, 5th and 6th grades showed unbalanced division for picture, figure, table unite and evaluation type of all units doesn’t show diversity. 2. The validity of textbook contents on practical arts was found to be the highest for 3rd grade textbook and the lowest for 6th grade one. Among the validity of the evaluation items,‘differentiation with other subject’and ‘usefulness of living’showed high scores, wheres ‘fitness of child level’marked lowest score. 3. There was no significant difference Among the validity contents of teachers based on socio-demographic variables.

• Journal of Life Science
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• v.19 no.6
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• pp.735-743
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• 2009

The common word flavonoids is often used to classify a family of natural compounds, highly abundant in all higher plants, that have received significant therapeutic interest in recent years. Naringin is associated with a reduced risk of heart disease, neurodegenerative disease, cancer and other chronic diseases; however the molecular basis of this effect remains to be elucidated. Thus we attempted to elucidate the anti-allergic effect of Naringin in ovalbumin (OVA)-induced asthma model mice. The OVA-induced mice showed allergic reactions in the airways. These included an increase in the number of eosinophils in bronchoalveolar lavage (BAL) fluid, an increase in inflammatory cell infiltration into the lung around blood vessels and airways, airway luminal narrowing, and the development of airway hyper-responsiveness (AHR). The administration of Naringin before the last airway OVA challenge resulted in a significant inhibition of all asthmatic reactions. Accordingly, this study may provide evidence that Naringin plays a critical role in the amelioration of the pathogenetic process of asthma in mice. These findings provide new insight into the immunopharmacological role of Naringin in terms of its effects on asthma in mice.

• The Journal of Natural Sciences
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• v.8 no.1
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• pp.71-80
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• 1995

This experiment was conducted to investigate the effect of raising seedling methods of cold water, low night temperature, and abandoned mine on forcing culture of strawberry. The results were as follows ;1. $17^{\circ}C$ cold water alone and cold water plus 8-hour short day treatments significantly accelerated the flower bud differentiation of Nyoho cultivar to 11 and 15 days, respectively, comparing to common soil raising seedling.2. The date of flower bud differentiation of Nyoho cultivar as influenced by cold water treatment the 17th, the 13th and the 10th of September, respectively, when the seedlings were treated on the 10th of September and on the 25th and the 10th of August in 1991. In 1992, data showed that the flower bud differentiation dates were the 4th and the 2nd of September and the 29th of August when cold water treatment was done on the 10th of August and on the 25th and the 10th of July.3. The first harvest date when Nyoho cultivar was treated by cold water for 30days from Jul. 25 was Nov. 10, this implying that the harvesting day could advanced to 19 days comparing to that by the common soil raising seedling method. The resulting yield was recorded to 21.94 ton per hectare.4. Regardless of the starting date of the treatment, $13^{\circ}C$ low night temperature plus 8-plus short day treatments for 20 days required 17 days to differentiate the flower bud of Nyoho cultivar. Harvesting day could be advanced to 59 days comparing to that by the common raising seedling method when the seedling was treated on July 25, this resulting in increasing the total yield obtained by April 14 of following year to 8.25 ton per hectare.5. When the seedlings of both Nyoho and Hokowase cultivars were raised under the condition of abandoned mine, flowering and harvest date were earlier by the treatment for 20 days than that for 30 days or 40 days. The highest yiesd obtained was recorded in Nyoho cultivar or 1.88 ton per hectare.

• Clinical and Experimental Reproductive Medicine
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• v.31 no.1
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• pp.19-27
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• 2004

Objective: This study was to examine the in vitro neural cell differentiation patterns of human embryonic stem (hES) cells following treatment of various neurotrophic factors [basic fibroblast growth factor (bFGF), retinoic acid (RA), brain derived neurotrophic factor (BDNF) and transforming growth factor (TGF)-$\alpha$], particulary in dopaminergic neuron formation. Methods: The hES cells were induced to differentiate by bFGF and RA. Group I) In bFGF induction method, embryoid bodies (EBs, for 4 days) derived from hES were plated onto gelatin dish, selected for 8 days in ITSFn medium and expanded at the presence of bFGF (10 ng/ml) for another 6 days followed by a final differentiation in N2 medium for 7, 14 and 21 days. Group II) For RA induction, EBs were exposed of RA ($10^{-6}M$) for 4 days and allowed to differentiate in N2 medium for 7, 14 and 21 days. Group III) To examine the effects of additional neurotrophic factors, bFGF or RA induced cells were exposed to either BDNF (10 ng/ml) or TGF-$\alpha$ (10 ng/ml) during the 21 days of final differentiation. Neuron differentiation and dopamine secretion were examined by indirect immunocytochemistry and HPLC, respectively. Results: The bFGF or RA treated hES cells were resulted in similar neural cell differentiation patterns at the terminal differentiation stage, specifically, 75% neurons and 11% glial cells. Additionally, treatment of hES cells with BDNF or TGF-$\alpha$ during the terminal differentiation stage led to significantly increased tyrosine hydroxylase (TH) expression of a dopaminergic neuron marker, compared to control (p<0.05). In contrast, no effect was observed on the rate of mature neuron (NF-200) or glutamic acid decarboxylase-positive neurons. Immunocytochemistry and HPLC analyses revealed the higher levels of TH expression (20.3%) and dopamine secretion (265.5 $\pm$ 62.8 pmol/mg) in bFGF and TGF-sequentially treated hES cells than those in $\alpha$ RA or BDNF treated hES cells. Conclusion: These results indicate that the generation of dopamine secretory neurons from in vitro differentiated hES cells can be improved by TGF-$\alpha$ addition in the bFGF induction protocol.

• IMMUNE NETWORK
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• v.15 no.4
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• pp.199-205
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• 2015

T-bet is a critical transcription factor that regulates differentiation of Th1 cells from $CD4^+$ precursor cells. Since T-bet directly binds to the promoter of the IFN-${\gamma}$ gene and activates its transcription, T-bet deficiency impairs IFN-${\gamma}$ production in Th1 cells. Interestingly, T-bet-deficient Th cells also display substantially augmented the production of IL-2, a T cell growth factor. Exogenous expression of T-bet in T-bet deficient Th cells rescued the IFN-${\gamma}$ production and suppressed IL-2 expression. IFN-${\gamma}$ and IL-2 reciprocally regulate Th cell proliferation following TCR stimulation. Therefore, we examined the effect of T-bet on Th cell proliferation and found that T-bet deficiency significantly enhanced Th cell proliferation under non-skewing, Th1-skewing, and Th2-skewing conditions. By using IFN-${\gamma}$-null mice to eliminate the anti-proliferative effect of IFN-${\gamma}$, T-bet deficiency still enhanced Th cell proliferation under both Th1- and Th2-skewing conditions. Since the anti-proliferative activity of T-bet may be influenced by IL-2 suppression in Th cells, we examined whether T-bet modulates IL-2-independent cell proliferation in a non-T cell population. We demonstrated that T-bet expression induced by ecdysone treatment in human embryonic kidney (HEK) cells increased IFN-${\gamma}$ promoter activity in a dose dependent manner, and sustained T-bet expression considerably decreased cell proliferation in HEK cells. Although the molecular mechanisms underlying anti-proliferative activity of T-bet remain to be elucidated, T-bet may directly suppress cell proliferation in an IFN-${\gamma}$- or an IL-2-independent manner.