• 융합보안논문지
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• 제13권3호
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• pp.71-77
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• 2013

우리나라는 보안산업 현장에 적용할 적합한 비즈모델 분석 방법론을 발견하기 어렵고 단편적 이론은 존재하지만 종합적 분석 방법론은 희소한 실정이다. 정보보안 기업 비즈모델 분석은 외부요인과 내부요인에 관해 수집된 정보를 통합하고 포괄적으로 분석하는 정보시스템 개발이 요구된다. 비즈모델 분석을 위한 정보시스템의 소프트웨어 아키텍처는 시스템 설계의 초기 결정사항으로서 초기 결정은 설계, 개발, 테스트, 유지보수에 지속적인 영향을 미친다. 정보보안 비즈모델 분석시 BMO에 기반한 소프트웨어 아키텍쳐는 정보시스템의 목적이나 사명 수행을 지원 한다. 정보보안 비즈모델 분석을 위한 정보시스템은 여러 이해관계자들이 사명과 환경을 결정하며 그 결과가 아키텍처 기술서로 문서화 되어야 활용될 수 있다. 아키텍처 기술서는 소프트웨어 아키텍처를 결정한 근거를 제시하기 때문이다.

• The Journal of Advanced Prosthodontics
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• 제7권4호
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• pp.312-316
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• 2015

PURPOSE. This study aimed to present the clinical applicability of restorations fabricated by a new method, by comparing the bond strength of between ceramic powder with different coefficient of thermal expansion and alloys fabricated by Selective laser sintering (SLS). MATERIALS AND METHODS. Fifty Co-Cr alloy specimens ($25.0{\times}3.0{\times}0.5mm$) were prepared by SLS and fired with the ceramic ($8.0{\times}3.0{\times}0.5mm$) (ISO 9693:1999). For comparison, ceramics with different coefficient of thermal expansion were used. The bond strength was measured by three-point bending testing and surfaces were observed with FE-SEM. Results were analyzed with a one-way ANOVA (${\alpha}$=.05). RESULTS. The mean values of Duceram Kiss ($61.18{\pm}6.86MPa$), Vita VM13 ($60.30{\pm}7.14MPa$), Ceramco 3 ($58.87{\pm}5.33MPa$), Noritake EX-3 ($55.86{\pm}7.53MPa$), and Vintage MP ($55.15{\pm}7.53MPa$) were found. No significant difference was observed between the bond strengths of the various metal-ceramics. The surfaces of the specimens possessed minute gaps between the additive manufactured layers. CONCLUSION. All the five powders have bond strengths higher than the required 25 MPa minimum (ISO 9693); therefore, various powders can be applied to metal structures fabricated by SLS.

• The Journal of Advanced Prosthodontics
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• 제3권3호
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• pp.166-171
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• 2011

PURPOSE. The purpose of this study is to evaluate and compare the shear bond strength of the gingiva-colored composite resin and the tooth-colored composite resin to porcelain, metal and zirconia. MATERIALS AND METHODS. Sixty cylindrical specimens were fabricated and divided into the following 6 groups (Group 1-W: tooth-colored composite bonded to porcelain, Group 1-P: gingiva-colored composite bonded to porcelain, Group 2-W: tooth-colored composite bonded to base metal, Group 2-P: gingiva-colored composite bonded to base metal, Group 3-W: tooth-colored composite bonded to zirconia, Group 3-P: gingiva-colored composite bonded to zirconia). The shear bond strength was measured with a universal testing machine after thermocycling and the failure mode was noted. All data were analyzed using the two-way analysis of variance test and the Bonferroni post-hoc test at a significance level of 0.05. RESULTS. The mean shear bond strength values in MPa were 12.39, 13.42, 8.78, 7.98, 4.64 and 3.74 for Group 1-W, 1-P, 2-W, 2-P, 3-W and 3-P, respectively. The difference between the two kinds of composite resin was not significant. The shear bond strength of Group 1 was the highest and that of Group 3 was the lowest. The differences among Group 1, 2 and 3 were all significant (P<.05). CONCLUSION. The shear bond strength of the gingiva-colored composite was not less than that of the tooth-colored composite. Thus, repairing or fabricating ceramic restorations using the gingiva-colored composite resin can be regarded as a practical method. Especially, the prognosis would be fine when applied on porcelain surfaces.

• Asian-Australasian Journal of Animal Sciences
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• 제16권8호
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• pp.1087-1092
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• 2003

As an experimental reference population, crosses between Korean native pig and Landraces were established and information on growth traits was recorded. Animals were genotyped for 24 microsatellite markers covering chromosomes 2, 6, and 7 for partial-genome scan to identify chromosomal regions that have effects on growth traits. quantitative trait loci (QTL) effects were estimated using interval mapping by the regression method under the line cross models with a test for imprinting effects. For test of presence of QTL, chromosome-wide and single position significance thresholds were estimated by permutation test and normal significance threshold for the imprinting test were derived. For tests against the Mendelian model, additive and dominance coefficients were permuted within individuals. Thresholds (5% chromosome-wide) against the no-QTL model for the analyzed traits ranged from 4.57 to 4.99 for the Mendelian model and from 4.14 to 4.67 for the imprinting model, respectively. Partial-genome scan revealed significant evidence for 4 QTL affecting growth traits, and 2 out of the 4 QTLs were imprinted. This study demonstrated that testing for imprinting should become a standard procedure to unravel the genetic control of multi-factorial traits. The models and tests developed in this study allowed the detection and evaluation of imprinted QTL.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3383-3389
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• 2014

Background: Prostate cancer is rapidly increasing in Korea and professional societies have requested adding prostate specific antigen (PSA) testing to the National Cancer Screening Program (NCSP), but this started a controversy in Korea and neutral evidence on this issue is required more than ever. The purpose of this study was to provide economic evidence to the decision makers of the NCSP. Materials and Methods: A cost-utility analysis was performed on the adoption of PSA screening program among men aged 50-74-years in Korea from the healthcare system perspective. Several data sources were used for the cost-utility analysis, including general health screening data, the Korea Central Cancer Registry, national insurance claims data, and cause of mortality from the National Statistical Office. To solicit the utility index of prostate cancer, a face-to-face interview for typical men aged 40 to 69 was conducted using a Time-Trade Off method. Results: As a result, the increase of effectiveness was estimated to be very low, when adopting PSA screening, and the incremental cost effectiveness ratio (ICER) was analyzed as about 94 million KRW. Sensitivity analyses were performed on the incidence rate, screening rate, cancer stage distribution, utility index, and treatment costs but the results were consistent with the base analysis. Conclusions: Under Korean circumstances with a relatively low incidence rate of prostate cancer, PSA screening is not cost-effective. Therefore, we conclude that adopting national prostate cancer screening would not be beneficial until further evidence is provided in the future.

• Asian-Australasian Journal of Animal Sciences
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• 제17권12호
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• pp.1746-1750
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• 2004

The PBM ${BioSign}^{TM}$ Salmonella (PBMS) test kit based on an mmunochromatographic method was evaluated for the screening of Salmonella spp. in pure cultures, and 80, 15, and 10 artificially and naturally contaminated, and negative controlled food samples, respectively. The PBMS test involves presumptive qualitative procedures, detecting the presence of Salmonella spp. in foods within 26 h total testing period and allowing the user to release negative products 70 h earlier than the conventional methods. The PBMS test using Buffered Peptone Water and Rappaport-Vassiliadis broth was evaluated for 10 different food types for various Salmonella spp. It showed detection limits of 1 to 25 colony forming units (CFU)/25 g. No cross-reaction was observed, particularly to other gramnegative bacteria. These results indicate the PBMS test is a rapid and inexpensive procedure for the screening of Salmonella spp. present at low concentrations (1 to 25 CFU/25 g) in foods.

• 셀메드
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• 제10권4호
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• pp.30.1-30.4
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• 2020

Background: Tiryaq-e-arba is a polyherbal Unani antidote/antivenom formulation used in the management of poisoning due to snake bite, scorpion bite as well as in cold poisons since time immemorial. Objectives: Tiryaq-e-arba was not evaluated scientifically before this study carried out, therefore it was studied for antivenom activity by testing on plasma fibrinogen level in Russell's Viper envenomation in rabbits. Material &Methods: The anti-venom activity of the test drug was studied by observing its effect on plasma fibrinogen level in Russell's Viper envenomation in rabbits by the method of Netelson. Results: The plasma fibrinogen level was found to be 171±665.04 mg/100 ml of blood, 36.18±1.12 mg/100 ml of blood, 33.14±0.52 mg/100 ml of blood and 17.9±1.65 mg/100 ml of blood at 0, 1, 3 and 6 hours respectively in control animals while in the test animal it was found to be 157.13±3.44 mg/100 ml of blood, 41.13±2.69 mg/100 ml of blood, 62.09±1.65 mg/100 ml of blood and 54.39±0.73 mg/100 ml of blood respectively. The test showed that though the plasma fibrinogen level in the test lower at 0 hour but it was greater in the control animals at 1, 3 and 6 hours. The increase in plasma fibrinogen level in the test animals at 3 and 6 hours was statistically significant (P<0.001). Conclusions: The finding of the present study was that Tiryaq-e-arba possesses antivenom activity which scientifically support the Unani claim that it is Dafe-Sumoom-al-Hevan (Antivenom or Antidote) and the use of this preparation in corresponding diseases.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2063-2068
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• 2012

Aim: Liquid-based cytology is the most often used method for cervical cancer screening, but it is relatively insensitive and frequently gives equivocal results. Used as a complementary procedure, the high-risk human papillomavirus (HPV) DNA test is highly sensitive but not very specific. The human telomerase RNA gene (TERC) is the most often amplified oncogene that is observed in cervical precancerous lesions. We assessed genomic amplification of TERC in liquid-based cytological specimens to explore the optimal strategy of using this for cervical cancer screening. Methods: Six hundred and seventy-one residual cytological specimens were obtained from outpatients aged 25 to 64 years. The specimens were evaluated by the Digene Hybrid Capture 2 (HC2) HPV DNA test and fluorescence in situ hybridization (FISH) with a chromosome probe to TERC (3q26). Colposcopic examination and histological evaluation were performed where indicated. Results: The TERC positive rate was higher in the CIN2+ (CIN2, CIN3 and SCC) group than in the normal and CIN 1 groups (90.0% vs. 10.4%, p < 0.01). In comparison with the HC2 HPV DNA test, the TERC amplification test had lower sensitivity but higher specificity (90.0% vs. 100.0%, 89.6% vs. 44.0%, respectively). TERC amplification test used in conjunction with the HC2 HPV DNA test showed a combination of 90.0% sensitivity and 92.2% specificity. Conclusion: The TERC amplification test can be used to diagnose cervical precancerous lesions. TERC and HPV DNA co-testing shows an optimal combination of sensitivity and specificity for cervical cancer screening.

• 정보교육학회논문지
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• 제8권2호
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• pp.261-268
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• 2004

정부에서는 지식정보화사회에 대비하여 정보통신을 위한 인프라를 구축하고 있으며, 이와 함께 정보통신기술 교육을 강화하고 있다. 그러나 정보통신 활용 교육을 위해서는 학습자들의 정보소양 능력이 전제가 되어야 하나, 이를 위한 체계적인 교육과정과 시간이 부족하기 때문에 많은 어려움이 지적되고 있다. 본 논문에서는 이러한 문제점을 해결하기 위하여 문항반응이론을 이용한 웹 기반의 컴퓨터 개별 적응평가 시스템을 개발하였다. 학습자들은 친숙한 웹 인터페이스를 이용하여 학교 또는 가정에서 자신의 정보소양 능력을 평가해 보고, 그 결과에 따라 보충 또는 심화학습을 함으로써 원활한 ICT 활용 교육이 이루어 질 수 있을 것이다. 또한 본 시스템은 현재 추진하고 있는 초 중 고 정보통신 소양 인증제를 위한 효과적인 평가 방법이 될 수 있을 것이다.

• 정보처리학회논문지D
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• 제12D권4호
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• pp.569-582
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• 2005

인터넷을 통한 정보의 교류와 비즈니스가 활발해지면서 웹 기반 소프트웨어도 확대되고 있고 그만큼 품질 측면의 노력이 중요하다. 웹 컨텐츠의 링크나 웹 기반 프로그램을 검증하는 연구가 시도되었으나 다양한 웹 기반 구성 방법들을 커버하는 방법은 찾기 어려웠고 또한 적용 실험이 부족하다. 이 논문에서는 다양한 동적인 웹 기반 소프트웨어들을 타입별로 나누어 보고 동일한 방법으로 모델링 한 후 테스트 케이스를 생성하는 방법을 제안한다. 웹 기반 소프트웨어를 구성하는 개체들을 파악한 후 이를 개체 제어흐름 그래프(Object Control of Flow Graph)와 개체 관계 다이어그램(Object Relationship Diagram)으로 모델링 한다. 모델에서 테스트 경로를 파악하고 테스트 키 포인트를 구동하는 테스트 케이스를 찾는다. 제안한 방법으로 다섯 가지 타입의 웹 기반 소프트웨어를 적용하여 실용성을 보였으며 이제까지 제안된 방법과 어떤 차이를 보이는지 비교하였다.