• Title/Summary/Keyword: Testing & Evaluation Method

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Availability of CLSI method and MicroScan MICroSTREP plus panel for Antimicrobial Susceptibility Testing of α-hemolytic streptococci Isolated from Patients (환자(患者)에서 분리한 연쇄상구균(連鎖狀球菌)에 대한 CLSI방법(方法)과 MicroScan MICroSTREP plus panel의 항균제(抗菌劑) 감수성(感受性) 검사(檢査)의 유용성(有用性) 고찰(考察))

  • Kim, Sang-Ha;Kim, Sang-Ha;Kim, Young-Kwon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.11
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    • pp.4951-4958
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    • 2011
  • The purpose of this study was availability for the classical test method. The test were called CLSI(Clinical and Laboratory Standards Institute) that was disk diffusion method, the newly designed E-test(made use disk diffusion method) can estimate the MIC and modified broth microdilution method that was standardized. Those tests were observed by MicroScan MicroSTREP plus panel. Target strains were 53 strains of S.pneumoniae and 51 strains of ${\alpha}$-hemolytic streptococci which were separated from the inpatient in university hospital for 6 months from February to August, 2009. The 9 antimicrobial agent of target evaluation were cefotaxime, chloramphenicol, clindamycin, erythromycin, levofloxacin, penicillin, tetracycline, trimethoprim/sulfamethoxazole, and vancomycin. researched comparative analysis both S.pneumoniae and ${\alpha}$-hemolytic streptococci. The result of the high concordance rates in ${\alpha}$-hemolytic streptococci was recognized formally in clinical microbiology laboratory.

Synthesis and Evaluation of Ecofriendly Nontoxic Cleaning Agents (무독성 친환경 세정제의 합성 및 평가에 관한 연구)

  • Kim, Jong Cheon;Ryu, Young;Hong, Yeon Heui;Kim, Seok Chan
    • Applied Chemistry for Engineering
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    • v.25 no.5
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    • pp.548-551
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    • 2014
  • In order to reduce toxicity on the human body, four new cleaning agents (1-4) containing ester and ether functionalities have been invented. The synthesized cleaning agents's physical properties, biodegradabilities, and $LD_{50}$ values, which were conducted by Korea Testing Certification Institute by using standard method, showed excellent values. A specimen for cleaning ability was prepared by cutting in $60{\times}40mm$ size of stainless steel plate. The surface of the above specimens was treated with four different kinds of contaminants, such as cutting oil, anti-rust oil, drawing oil, and lubricating oil. Contaminated specimens were then immersed in compounds (1-4) for 1 to 5 minutes to dissolve oil in the cleaning agent. The data indicate that all compounds (1-4) exhibit good cleaning ability toward four contaminant oils. It is also confirmed that these compounds can be applicable to various industrial cleaning fields as nontoxic and biodegradable cleaning agents because of their excellent biodegradabilities and $LD_{50}$ values.

Application of Indigenous Benthic Amphipods as Sediment Toxicity Testing Organisms

  • Lee, Jung-Suk;Lee, Kyu-Tae;Kim, Dong-Hoon;Kim, Chao-Kook;Lee, Jong-Hyeon;Park, Kun-Ho
    • Ocean Science Journal
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    • v.40 no.1
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    • pp.17-24
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    • 2005
  • A series of experiments were conducted to develop standard test organisms and test protocols for measuring sediment toxicity using candidate amphipods such as Mandibulophoxus mai, Monocorophium acherusicum, Haustorioides indivisus, and Haustorioides koreanus, which are indigenous to Korea. The relevant association of test species with sediment substrates was one of the important factors in sediment bioassay. The indigenous amphipods M mai and M. acherusicum were well associated with test sediments when they were exposed to various sediment substrates from sand to mud. The tolerant limits to various physico-chemical factors affecting bioassay results such as temperature, salinity and ammonia, as well as sensitivities to reference toxicant and contaminated sediments, were investigated using M. mai and M. acherusicum in the present study. These amphipods were tolerant to relatively wide ranges of salinity $(10{\sim}30\;psu)$ and ammonia (<50 ppm), and displayed relevant sensitivity to temperature as well. They are more sensitive to Cd, the reference toxicant, when compared to the standard test species used in other countries. Field-sediment toxicity tests revealed that M. mai would be more sensitive to sediment-associated pollutants than M. acherusicum, while the sensitivity of M. acherusicum was comparable to that of Leptocheirus plumulosus, which has been used as a standard test species in the United States of America. Overall results of this first attempt to develop an amphipod sediment toxicity test protocol in Korea indicated that M. mai and M. acherusicum would be applicable in the toxicity assessment of contaminated sediments, following the further evaluation encompassing various ecological and toxicological studies in addition to test method standardization.

Optimal Thresholds from Mixture Distributions (혼합분포에서 최적분류점)

  • Hong, Chong-Sun;Joo, Jae-Seon;Choi, Jin-Soo
    • The Korean Journal of Applied Statistics
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    • v.23 no.1
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    • pp.13-28
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    • 2010
  • Assuming a mixture distribution for credit evaluation studies, we discuss estimating threshold methods to minimize errors that default borrowers are predicted as non defaults or non defaults are regarded as defaults. A method by using statistical hypotheses tests, the most powerful test and generalized likelihood ratio test, for the probability density functions which are defined with the score random variable and the parameter space consisted of only two elements such as the default and non default states is proposed to estimate a threshold. And anther optimal thresholds to maximize classification accuracy measures of the accuracy and the true rate for ROC and CAP curves are estimated as equations related with these probability density functions. Three kinds of optimal thresholds in terms of the hypotheses testing, the accuracy and the true rate are obtained from normal random samples with various means and variances. The sums of the type I and type II errors corresponding to each optimal threshold are obtained and compared. Finally we discuss about their efficiency and derive conclusions.

A Study on Connection Strength Evaluation of Wall Facing/Geogrid Using I-type Connection Device (I형 연결장치를 이용한 전면블록/지오그리드 보강재의 연결강도 평가)

  • Han, Jung-Geun;Hong, Ki-Kwon;Cho, Sam-Deok;Lee, Kwang-Wu
    • Journal of the Korean Geosynthetics Society
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    • v.8 no.3
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    • pp.45-52
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    • 2009
  • The use of geogrid-reinforced earth wall technologies has progressed rapidly over the past 10 years in Korea because these technologies have advantages such as economical efficiency, graceful appearance, and easy construction. The geogrid used in the reinforced earth wall with concrete block facing can be subjected to damage among the upper and lower blocks and at the interface between the block and the geogrid. Therefore, when design of the geogrid-reinforced soil walls the required connection strength of the geogrid to the wall facing is an issue. In this study, new connection system between facing block and geogrid is developed to improve the damages of geogrid in the existing connection systems. The new connection devices are made of steel and have I-shape. This paper describes the test method and results of the laboratory testing for determination of connection strength in connection system using the I-type connection device.

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Clinical Characteristics of Cervical and Thoracic Radiculopathies: Non-Invasive Interventional Therapy (목 및 가슴신경뿌리병증의 임상적 고찰: 비침습적 중재시술치료)

  • Roh, Hakjae;Lee, Sang-Heon;Kim, Byung-Jo
    • Annals of Clinical Neurophysiology
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    • v.10 no.2
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    • pp.83-97
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    • 2008
  • Cervical and thoracic radiculopathies are among the most common causes of neck pain. The most common causes are cervical disc herniation and cervical spondylosis in patients with cervical radiculopathy, and diabetes mellitus and thoracic disc herniation in thoracic radiculopathy. A thorough history, physical examination, and testing that includes electrodiagnostic examination and imaging studies may distinguish radiculopathy from other pain sources. Although various electrodiagnostic examinations may help evaluate radiculopathy, needle electromyography is the most important, sensitive, and specific method. Outcome studies of conservative treatments have shown varying results and have not been well controlled or systematic. When legitimate incapacitating symptoms continue despite conservative treatment attempts, more invasive spinal procedures and intradiscal treatment may be appropriate. Surgery has been shown to have excellent clinical outcomes in patients with disc extrusion and neurological deficits. However, patients with minimal disc herniation have fair or poor surgical outcomes. In addition, conventional open disc surgery entails various inadvertent surgical related risks. Although there has not yet been a non-surgical interventional procedure developed with the therapeutic efficacy of open surgery, conservative procedures can offer substantial benefits, are less invasive, and avoid surgical complications. While more invasive procedures may be appropriate when conservative treatment fails, prospective studies evaluating cervical and thoracic radiculopathies treatment options would help guide practitioners toward optimally cost-effective patient evaluation and care.

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An Experimental Study of Seismic Retrofit on the Viaduct Bridge of Rail Transit (철도 고가교 기둥의 내진성능에 관한 실험적 연구)

  • Kim, Jinho;Shin, Hongyoung;Park, Yeonjun;Hur, Jinho
    • Journal of the Korean Society for Railway
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    • v.15 no.6
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    • pp.616-622
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    • 2012
  • Earthquake damage of viaduct bridge of railroad may give rise to social loss due to transport restrictions greater than cost of structural recovery. Therefore, viaduct bridge of railroad should have ensure adequate seismic performance. But, results of seismic performance evaluation, many of seismic retrofit was required. In this study, five scale models of columns were made and four of them were reinforced by HT-A(HyperTex & perforate Aluminum) which is improved than existing method. Testing the columns by constant axial load and cyclic lateral displacements, seismic performance of columns has been verified from the result of evaluating the stiffness, ductility and energy dissipation capacity.

Evaluation of Morphology and Water Flux for Polysulfone Flat Sheet Membrane with Conditions of Coagulation Bath and Dope Solution (응고조와 도프조성에 따른 폴리술폰 평막의 모폴로지 및 수투과도 평가)

  • Woo, Seung Moon;Chung, Youn Suk;Nam, Sang Yong
    • Membrane Journal
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    • v.22 no.4
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    • pp.258-264
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    • 2012
  • In this study, to research effect of coagulation bath and composition of dope solution, polysulfone flat sheet membrane was fabricated by phase inversion method. PEG and PVP were used as additive. Concentration of polymer and additive, composition of coagulation bath was controlled to prepare flat sheet membrane. And then the morphology and water flux of prepared membrane were measured by FE-SEM and water flux testing apparatus. The highest value of water flux was measured at the membrane prepared under a 15 wt% PSF, 25 wt% PEG conditions, and water as coagulation bath. The pure water flux of the membrane composed of PSf/PEG was drastically decreased with increasing amount of DMAc. We confirmed that change of amount in additive and composition in coagulation bath influence the morphology and water flux performance of the membrane.

A Study of the Construction of Comprehensive Flight Testing Infrastructure to Increase Aviation Safety (항공안전 증진을 위한 비행종합시험 인프라 구축 방안 연구)

  • Kim, Seung-Han;Kim, Gyou-Beom;Yim, Jae-Hyun
    • Journal of Convergence for Information Technology
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    • v.10 no.9
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    • pp.147-153
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    • 2020
  • As demand for drone test flight is rapidly increasing, it is difficult for Goheung Aviation Center alone to meet the test flight demand. Newly developed drones or modified existing aircraft carry potential flight risks due to unpredictable flight performance or poor pilot skill when performing test flights outside the test site. Therefore, it is necessary to ensure sufficient test flight space for the safety verification of manned and unmanned aircraft. Therefore, this study analyzed the status of domestic flight test site and chapter 5 of ICAO DOC 9184-AN / 902 Part 1 (Airport Planning Manual). And to build a comprehensive flight test infrastructure, the methodology for preliminary evaluation of candidate sites for flight test sites and a method for evaluating infrastructure test sites was presented.

Response of coal rock apparent resistivity to hydraulic fracturing process

  • Song, Dazhao;Wang, Enyuan;Qiu, Liming;Jia, Haishan;Chen, Peng;Wei, Menghan
    • Geomechanics and Engineering
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    • v.14 no.6
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    • pp.581-588
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    • 2018
  • In order to explore the comprehensive evaluation means of the extent of hydraulic fracturing region in coal seams, we analyzed the feasibility of detecting the response of coal rock direct current (DC) apparent resistivity to hydraulic-fracturing using Archie's theory, and conducted experimental researches on the response of DC resistivity in the hydraulic fracturing process using small-scale coal rock samples. The results show that porosity and water saturation are the two factors affecting the apparent resistivity of coal rock while hydraulic fracturing. Water has a dominant effect on the apparent resistivity of coal rock samples. The apparent resistivity in the area where water flows through is reduced more than 50%, which can be considered as a core affect region of hydraulic fracturing. Stress indirectly impacts the apparent resistivity by changing porosity. Before hydraulic fracturing, the greater axial load applied, the more serious the rupture in the samples, resulting in the greater apparent resistivity. Apparent resistivity testing is a potential regional method to evaluate the influence range of hydraulic fracturing in coal seams.