• Title/Summary/Keyword: Test and evaluation

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Antibacterial Activity of Platycarya strobilacea Extract and Stability of the Extract-containing Cream (굴피나무 추출물의 항균 활성 및 추출물을 함유한 크림의 안정성 분석)

  • Yang, Hee-Jung;Kim, Eun-Hee;Kang, Sung-Tae;Park, Soo-Nam
    • Microbiology and Biotechnology Letters
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    • v.37 no.2
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    • pp.170-175
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    • 2009
  • The extract of Platycarya strobilacea is known to possess a wide range of pharmacological activities including anti-inflammatory, anti-fungal, and anti-cancer properties. We have reported that the ethyl acetate fraction of Platycarya strobilacea (PS-ET fraction) has high potential as an antioxidant agent (J. Soc. Cosmet. Scientists Korea 34(4) 275, 2008). In this study, antibacterial activity of the fraction and stability of the cream containing 0.2% PS-ET fraction were investigated for the application to cosmetics. Antibacterial activity of PS-ET fraction against various skin pathogenic bacteria (Propionibacterium acnes, Staphylococcus aureus, and Pityrosporum ovale) was measured by minimum inhibitory concentration (MIC). MIC values of PS-ET fraction on P. acnes, S. aureus, and P. ovale were 0.13%, 0.06% and 0.25%, respectively. The results showed that the antibacterial activity of the fraction was the highest in the S. aureus. For the stability evaluation, pH and viscosity of the cream containing 0.2% PS-ET fraction were measured. The results showed that pH changes of the cream containing PS-ET fraction was lower than the control cream without PS-ET fraction. And the PS-ET fraction could repress the decrease of viscosity of the cream against sunlight treatment. These results suggest that the fraction of Platycarya strobilacea has high potential as bactericide against the skin pathogenic bacteria and could be added to improve the stability of cosmetic products.

The Effects of Trunk Stabilization Training on a Stroke Patient's Postural Control and Activities of Daily Living: A Sing Subject Design (뇌졸중 환자의 체간안정화 훈련이 자세조절과 일상생활동작에 미치는 영향: 단일사례연구)

  • Nam, Ju-Hyeon;Shim, Gyeong-Bo;Gwak, Seong-Won
    • The Journal of Korean society of community based occupational therapy
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    • v.4 no.1
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    • pp.75-84
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    • 2014
  • Objective : This study intends to suggest an effective clinical intervention method for stroke patients by applying a trunk stabilization training program to a single stroke patient and investigating and analyzing the effects of the program on postural control and activities of daily living. Methods : The subject of this study was a 75 year-old female stroke patient hospitalized in C Hospital located in Gyeongju, Gyeongsangbuk-do. As for the research design, A-B-A reversal design was used with a single subject design; and the research period was a total of five weeks from April 21, 2014 to May 23, 2014. As for the research process, a total of 15 sessions were carried out including three sessions of baseline(A), nine sessions of an intervention period(B), and three sessions of maintenance(A'); and the trunk stabilization program was applied during the intervention period. To evaluate the participant's postural control and activities of living life, the Postural Assessment Scale for Stroke(PASS) and the modified Barthel Index(MBI) were used. Visual analysis was used in which collected data were plotted on a graph, using Microsoft Office Excel 2013. Results : In the postural control test, the mean scores improved from 11.7 in the baseline phase to 14.8 in the intervention phase and 15.3 in the maintenance phase. In the evaluation of activities of daily living, the score improved from 66(medium dependence) during the baseline period to 80(low dependence) after intervention and at the maintenance phase. Conclusion : It was found that the trunk stabilization training program showed effects on the stroke patient's postural control or alignment, and furthermore a beneficial improvement in the patient's performing the activities of daily living, as well.

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Consideration of Shoulder Joint's Image with the Changed Tube Angle of the Shoulder Oblique Projection in Supine Position (Supine 자세에서 Shoulder oblique촬영시 Tube angle 변화에 따른 Shoulder joint에 대한 고찰)

  • Seo, Jae-Hyun;Choi, Nam-Gil
    • Journal of radiological science and technology
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    • v.31 no.2
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    • pp.109-114
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    • 2008
  • There is a standard shoulder oblique method (Grashey method) available to view the shoulder joint. This method projects AP view of the shoulder joint so that the Humerus head's subuxation or joint degeneration can be easily visualized. However, in this view, the patients, with supine or sitting or erect position, have to keep their body obliquely. Whereas, the patients who are not well or operated, usually feel very uncomfortable to keep their body in this position and hence, we need other persons' help and much efforts will be needed to get the good quality shoulder joint view. Therefore, we thought of examining a method which shows the joint well by angling the tube to Medio-Lateral direction and without keeping the patients' one side upward in supine position. For this study, total 15 subjects with no history of neurological or psychiatric illness, were recruited for examinations. They consisted of 9 males and 6 females. Statistic group analysis was performed with ANOVA test. Scores of the evaluation of the experts were $1.10{\pm}0.54$ at $25^{\circ}$, $2.50{\pm}0.50$ at 30^{\circ}$, $2.85{\pm}0.36$ at $35^{\circ}$ and $2.33{\pm}0.47$ at $40^{\circ}$, respectively, and they were significant(p<0.05, Table 1). Joint space of the Humerus head and Scapula were well distinguished at $35^{\circ}$, $30^{\circ}$ and $40^{\circ}$ with the almost same score. However, the degree of distortion at $40^{\circ}$ was more severe than that at $30^{\circ}$. Ultimately, $30-35^{\circ}$ views were shown to yield good quality shoulder oblique images. In conclusion, this method may be very useful for the patients who are uncomfortable and for the emergency patients. In order to get similar or comparable view, the same X-tube angle is recommended to be used before and after the operation. Therefore, we hope that this new angled method seems to be efficient.

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Experimental Study on the Effect of Filter Layers on Pumping Capacity and Well Efficiency in an Unconfined Aquifer (자유면대수층에서 필터층이 취수량 및 우물효율에 미치는 영향에 대한 실험적 연구)

  • Song, Jae-Yong;Lee, Sang-Moo;Choi, Yong-Soo;Jeong, Gyo-Cheol
    • The Journal of Engineering Geology
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    • v.27 no.4
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    • pp.405-416
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    • 2017
  • This study evaluated a model unconfined aquifer comprising a sand or gravel layer, a filter layer, a pumping well, and an observation well. The model was employed in step drawdown tests and then used to assess the permeability of each test tank. The optimal yield and well efficiency were then calculated. Evaluation of yield by step in sand layer filters of equal thickness gave optimized watering rates of 22.03 L/min in the double filter and 19.71 L/min in the single filter. The double filter's yield was 115.0% that of the single filter. A comparison of double and single filters, each 10 cm thick, showed the double filter to have a maximum yield of 182.7%. Yields for the gravel layer were 73.56 L/min for a double filter and 65.47 L/min for a single filter of the same thickness; the former value is 112.3% of that of the latter. Comparison of double and single filters with 10-cm-thick gravel layers revealed that the double filter had a maximum yield of 160.9%. Results for sand wells showed the double filter to have a maximum efficiency of 70.4% and the single filter to have a minimum efficiency of 37.1%. Gravel-layer well efficiencies were >66.5% for both double and single filters (each 30 cm thick), but only 22.5% for a 10-cm-thick single filter. This study confirms that permeability improved as the filter material became thicker; it also shows that a double filter has a higher yield and well efficiency than a single filter. These results can be applied to the practical design of wells.

Comparative Evaluation of Neighborhood Parks in Korea and China based on the Place Attachment Model (장소애착 모델에 근거한 한국·중국 근린공원의 비교평가)

  • Yang, Lei;Lee, Shiyoung
    • Journal of the Korean Institute of Landscape Architecture
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    • v.45 no.3
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    • pp.21-29
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    • 2017
  • In this study of visitor place attachment to parks, Scannel and Gilford considered the dimensions of place attachment, and proposed the theoretical framework of PPP(Place, Person, Process) that should be systematically studied from the perspective of person, place and psychological processes. According to Scannel's theoretical basis, this paper puts forward the hypothesis of a structure model of place attachment. In the model, the five independent variables of people, places, cognition, emotion, and behavior have influenced the dependent variable of place attachment. The questionnaire was conducted on 18 neighborhood parks in Kunming, China, and the residents of the 5 neighborhood parks in Daejeon, South Korea. A total of 1,645 valid samples of the questionnaire survey were collected. Through confirmatory factor analysis(CFA) results of the inspection of the various elements, it was shown that the reliabilities of 6 latent variables, such as people, places, cognition, affection, behavior and place attachment, which were composed with the observed variables(30 observed variables in Daejeon, 19 observed variables in Kunming), were all above 0.7 and the data were fit for this study. The hypothesis test results found that the physical environment of the neighborhood parks such as a comfortable environment, pleasant road and convenient facilities would increase the rate of visitors coming back. From the park management perspective, to increase the amount of visitors to the park, the park should increase visibility, provide more organized, varied activities and meetings, or special exhibitions according to the particular characteristics of the individual park, to increase awareness of the park. From the park visitors' psychological perspective, visitors are seeking to enjoy the park facilities and environment not only to bring physical relaxation, but also to bring about a psychological cure. With the commonality of attachment structure between the two countries, to improve the place attachment of neighborhood park visitors, collecting regularly visitor feedback will facilitate the sustainable development of neighborhood park attachment.

The Evaluation of Resolution Recovery Based Reconstruction Method, Astonish (Resolution Recovery 기반의 Astonish 영상 재구성 기법의 평가)

  • Seung, Jong-Min;Lee, Hyeong-Jin;Kim, Jin-Eui;Kim, Hyun-Joo;Kim, Joong-Hyun;Lee, Jae-Sung;Lee, Dong-Soo
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.1
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    • pp.58-64
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    • 2011
  • Objective: The 3-dimensional reconstruction method with resolution recovery modeling has advantages of high spatial resolution and contrast because of its precise modeling of spatial blurring according to the distance from detector plane. The aim of this study was to evaluate one of the resolution recovery reconstruction methods (Astonish, Philips Medical), compare it to other iterative reconstructions, and verify its clinical usefulness. Materials and Methods: NEMA IEC PET body phantom and Flanges Jaszczak ECT phantom (Data Spectrum Corp., USA) studies were performed using Skylight SPECT (Philips) system under four different conditions; short or long (2 times of short) radius, and half or full (40 kcts/frame) acquisition counts. Astonish reconstruction method was compared with two other iterative reconstructions; MLEM and 3D-OSEM which vendor supplied. For quantitative analysis, the contrast ratios obtained from IEC phantom test were compared. Reconstruction parameters were determined by optimization study using graph of contrast ratio versus background variability. The qualitative comparison was performed with Jaszczak ECT phantom and human myocardial data. Results: The overall contrast ratio was higher with Astonish than the others. For the largest hot sphere of 37 mm diameter, Astonish showed about 27.1% and 17.4% higher contrast ratio than MLEM and 3D-OSEM, in short radius study. For long radius, Astonish showed about 40.5% and 32.6% higher contrast ratio than MLEM and 3D-OSEM. The effect of acquired counts was insignificant. In the qualitative studies with Jaszczak phantom and human myocardial data, Astonish showed the best image quality. Conclusion: In this study, we have found out that Astonish can provide more reliable clinical results by better image quality compared to other iterative reconstruction methods. Although further clinical studies are required, Astonish would be used in clinics with confidence for enhancement of images.

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A study on Evaluating Validity of SNR Calculation Using a Conventional Two Region Method in MR Images Applied a Multichannel Coil and Parallel Imaging Technique (다중채널코일과 병렬영상기법 이용 시 두영역측정법을 사용한 신호대잡음비 측정의 문제점)

  • Choi, Kwan-Woo;Son, Soon-Yong;Min, Jung-Whan;Kwon, Kyung-Tae;Yoo, Beong-Gyu;Lee, Jong-Seok
    • Journal of radiological science and technology
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    • v.38 no.4
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    • pp.403-410
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    • 2015
  • The purpose of this study was to investigate the problems of a signal to noise ratio measurement using a two region measurement method that is conventionally used when using a multi-channel coil and a parallel imaging technique. As a research method, after calculating the standard SNR using a single channel head coil of which coil satisfies three preconditions when using a two region measurement method, we made comparisons and evaluations after calculating an SNR by using a two region measurement method of which method is problematic because it is used without considering the methods recommended by reputable organizations and the preconditions at the time of using a multi-channel coil and a parallel imaging technique. We found that a two region measurement method using a multi-channel coil and a parallel imaging technique shows the highest relative standard deviation, and thus shows a low degree of precision. In addition, we found out that the difference of SNR according to ROI location was very high, and thus a spatial noise distribution was not uniform. Also, 95% confidence interval through Blend-Altman plot is the widest, and thus the conformity degree with a two region measurement method using the standard single channel head coil is low. By directly comparing an AAPM method, which serves as a standard of a performance evaluation test of a magnetic resonance imaging device under the same image acquisition conditions, an NEMA method which can accurately determine the noise level in a signal region and the methods recommended by manufacturers of a magnetic resonance imaging device, there is a significance in that we quantitatively verified the inaccurate problems of a signal to noise ratio using a two region measurement method when using a multi-channel coil and a parallel imaging technique of which method does not satisfy the preconditions that researchers could overlook.

Evaluation of Dosimetric Characteristics of Small Field in Cone Versus Square Fields Based on Linear Accelerators(LINAC) for Stereotactic Radiosugery(SRS) (선형가속기를 기반으로 한 뇌정위 방사선 수술 시 전용 콘과 정방형 소조사면의 선량 특성에 관한 고찰)

  • Yoon, Joon;Lee, Gui-Won;Park, Byung-Moon
    • Journal of radiological science and technology
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    • v.33 no.1
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    • pp.61-66
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    • 2010
  • In this paper we evaluated small field dose characteristics of exclusive cone fields versus square fields for stereotactic radiosugery (SRS) which is based on linear accelerators (LINAC). For this test, we used a small beam detector (stereotactic fields detector : SFD) with a 6 MV photon beam and a water phantom system (IBA, Germany). Percentage depth dose (PDD) was measured for different field sets (cones : ${\Phi}1\;cm$, ${\Phi}2\;cm$, ${\Phi}3\;cm$ ; square fields : $1{\times}1\;cm^2$, $2{\times}2\;cm^2$, $3{\times}3\;cm^2$) at a source skin distance (SSD) of 100 cm. We measured the point depths at 1.5 cm, 5 cm, 10 cm, 20 cm, and 30 cm. The output factors were measured under the same geometrical conditions of the PDD and normalized at the maximum dose depth. To analyze the penumbra, we measured the dose profile with 95 cm of SSD, 5 cm of depth for each field sizes (${\Phi}1\;cm$, ${\Phi}3\;cm$, $1{\times}1\;cm^2$, and $3{\times}3\;cm^2$) using SFD. We obtained the values for every 1 mm interval in the physical field (90%) and 0.5 mm interval in the penumbra region (20 to 80%). The PDD variation of exclusive cones and square fields were 4.3 to 7.9% lesser than the standard field size ($10{\times}10\;cm^2$. The variation of PDD was reduced while the field size was increased. To compare the beam quality, we analyzed the $PDD_{20,10}$ and the results showed under the 1% of variations for all experiments except for ${\Phi}1\;cm$ cone and $1{\times}1\;cm^2$ fields. Output factors of exclusive cone were increased 3.1~4.6% than the square fields, and the penumbra region of exclusive cone was reduced 20% as compared to the square fields. As the previous researches report, it is very important for SRS and SFD that precise dosimetry in small beam fields. In this paper, we showed the effectiveness of exclusive cone, compared to square field. And we will study on the various detector characteristics for small beam fields.

Effect of Sargassum sagamianum Extract on Shelf-life and Improved Quality of Morning Bread (비틀대 모자반(Sargassum sagamianum) 추출물이 모닝빵의 저장성 및 품질에 미치는 영향)

  • Kim, Min-Ji;Kim, Koth-Bong-Woo-Ri;Lee, Chung-Jo;Kwak, Ji-Hee;Kim, Dong-Hyun;SunWoo, Chan;Jung, Seul-A;Kang, Ju-Youn;Kim, Hyun-Jee;Choi, Jung-Su;Choi, Ho-Duk;Ahn, Dong-Hyun
    • Korean Journal of Food Science and Technology
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    • v.43 no.6
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    • pp.723-728
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    • 2011
  • This study was performed to test the effect of Sargassum sagamianum extract (SSE) on shelf-life and improved quality in bread with 0.25, 0.5 and 0.75% added SSE. Bread with added SSE had reduced total microbial counts by 2 log cycles and mold cell counts by 3 log cycles. No changes in moisture content or pH occurred from days 3 to 9. In addition, bread with SSE had a lower yield of malonaldehyde than that of the control as shown by the TBARS assay. Yellowness increased in bread with added SSE, whereas lightness and redness decreased. In the sensory evaluation, taste, total preference, inner shape, and color of the bread containing 0.25 and 0.5% SSE were preferred. These results suggest that the adding 0.25 and 0.5% SSE to bread improved shelf-life and quality.

Antioxidant capacity and Raw 264.7 macrophage anti-inflammatory effect of the Tenebrio Molitor (갈색거저리(Tenebrio Molitor)의 항산화능과 Raw 264.7 대식세포의 항염증 효과)

  • Yu, Jae-Myo;Jang, Jae-Yoon;Kim, Hyeon-Jeong;Cho, Yong-Hun;Kim, Dong-in;Kwon, O-jun;Cho, Yeong-Je;An, Bong-Jeun
    • Food Science and Preservation
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    • v.23 no.6
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    • pp.890-898
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    • 2016
  • The purpose of this paper is to investigate potential anti-inflammatory and anti-oxidant effects of Tenebrio molitor. Macrophage cell response by outside stimulation leads expression of pro-inflammatory cytokines, such as tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$), interleukin-6 (IL-6), $interleukin-1{\beta}$ ($IL-1{\beta}$), and trigger expression of genes which are affected by inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), resulting in formation of inflammatory factors like nitric oxide (NO) and Prostaglandin $E_2$ (PGE2). Cell viability was determined by MTT assay. In order to investigate anti-inflammatory agents, the inhibitory effects on the production of lipopolysaccharide (LPS)-induced NO in RAW 264.7 cells were examined. T. Molitor significantly decreased the production of NO in a dose-dependent manner, and also reduced the expression of iNOS, a COX-2 protein. As a result, the levels of protein such as $PGE_2$, iNOS, COX-2 and MARKs were significantly reduced compared to non-treated group in T. Molitor water extract (TDW) treated group. Also, antioxidant effect of T. Molitor were investigated using DPPH, ABTS+ and superoxide anion radical scavenging activity tests in cell-free system. Antioxidant activity of T. molitor was found low in the DPPH radical scavenging test while high in the ABTS+ and superoxide anion radical scavenging activity tests. These results show that TDW could be an effective anti-pro-inflammatory and anti-oxidant agent.