• 제목/요약/키워드: Temporal Properties

검색결과 342건 처리시간 0.023초

Photoresponsive Hydrogels as Drug Delivery Systems

  • Abueva, Celine DG.;Chung, Phil-Sang;Ryu, Hyun-Seok;Park, So-Young;Woo, Seung Hoon
    • Medical Lasers
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    • 제9권1호
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    • pp.6-11
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    • 2020
  • Hydrogels have been developed and used in tissue engineering and regenerative medicine to deliver therapeutics to injured or diseased tissue because of their versatility and properties that can be tailored to match the natural extracellular matrix. Hydrogels can be made with a variety of physical and chemical properties combined with light responsiveness ideal for applications in different fields of medicine that require the spatiotemporal control of therapeutics. Light, as a stimulus, is relatively inexpensive, contact-free, noninvasive with high spatial resolution and temporal control, convenient and easy to use, and allows deep tissue penetration that is relatively harmless. Photoresponsive hydrogels are ideal candidates for on-demand drug delivery systems that are capable of sustained and controlled drug release, minimizing the side effects, and ensuring the activity and efficient delivery of drugs to the target tissue.

Modal tracking of seismically-excited buildings using stochastic system identification

  • Chang, Chia-Ming;Chou, Jau-Yu
    • Smart Structures and Systems
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    • 제26권4호
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    • pp.419-433
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    • 2020
  • Investigation of structural integrity has been a critical issue in the field of civil engineering for years. Visual inspection is one of the most available methods to explore deteriorative components in structures. Still, this method is not applicable to invisible damage of structures. Alternatively, system identification methods are capable of tracking modal properties of structures over time. The deviation of these dynamic properties can serve as indicators to access structural integrity. In this study, a modal tracking technique using frequency-domain system identification from seismic responses of structures is proposed. The method first segments the measured signals into overlapped sequential portions and then establishes multiple Hankel matrices. Each Hankel matrix is then converted to the frequency domain, and a temporal-average frequency-domain Hankel matrix can be calculated. This study also proposes the frequency band selection that can divide the frequency-domain Hankel matrix into several portions in accordance with referenced natural frequencies. Once these referenced natural frequencies are unavailable, the first few right singular vectors by the singular value decomposition can offer these references. Finally, the frequency-domain stochastic subspace identification tracks the natural frequencies and mode shapes of structures through quick stabilization diagrams. To evaluate performance of the proposed method, a numerical study is carried out. Moreover, the long-term monitoring strong motion records at a specific site are exploited to assess the tracking performance. As seen in results, the proposed method is capable of tracking modal properties through seismic responses of structures.

SPECTROSCOPIC ADMITTIVITY IMAGING OF BIOLOGICAL TISSUES: CHALLENGES AND FUTURE DIRECTIONS

  • Zhang, Tingting;Bera, Tushar Kanti;Woo, Eung Je;Seo, Jin Keun
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • 제18권2호
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    • pp.77-105
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    • 2014
  • Medical imaging techniques have evolved to expand our ability to visualize new contrast information of electrical, optical, and mechanical properties of tissues in the human body using noninvasive measurement methods. In particular, electrical tissue property imaging techniques have received considerable attention for the last few decades since electrical properties of biological tissues and organs change with their physiological functions and pathological states. We can express the electrical tissue properties as the frequency-dependent admittivity, which can be measured in a macroscopic scale by assessing the relation between the time-harmonic electric field and current density. The main issue is to reconstruct spectroscopic admittivity images from 10 Hz to 1 MHz, for example, with reasonably high spatial and temporal resolutions. It requires a solution of a nonlinear inverse problem involving Maxwell's equations. To solve the inverse problem with practical significance, we need deep knowledge on its mathematical formulation of underlying physical phenomena, implementation of image reconstruction algorithms, and practical limitations associated with the measurement sensitivity, specificity, noise, and data acquisition time. This paper discusses a number of issues in electrical tissue property imaging modalities and their future directions.

Development of Communication Protocol Verification Tool for Vital Railway Signaling Systems

  • Hwang, Jong-Gyu;Jo, Hyun-Jeong;Lee, Jae-Ho
    • Journal of Electrical Engineering and Technology
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    • 제1권4호
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    • pp.513-519
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    • 2006
  • As a very important part in development of the protocol, verifications for developed protocol specification are complementary techniques that are used to increase the level of confidence in the system functions by their specifications. Using the informal method for specifying the protocol, some ambiguity may be contained therein. This indwelling ambiguity in control systems can cause the occurrence of accidents, especially in the case of safety-critical systems. To clear the vagueness contained in the designed protocol, we use the LTS (Labeled Transition System) model to design the protocol for railway signaling. And then, we verify the safety and the liveness properties formally through the model checking method. The modal ${\mu}$-calculus, which is an expressive method of temporal logic, has been applied to the model checking method. We verify the safety and liveness properties of Korean standard protocol for railway signaling systems. To perform automatic verification of the safety and liveness properties of the designed protocol, a communication verification tool is implemented. The developed tools are implemented by C++ language under Windows XP. It is expected to increase the safety and reliability of communication protocol for signaling systems by using the developed communication verification tool.

유효가뭄지수(EDI)를 이용한 한반도 미래 가뭄 특성 전망 (Projection of Future Changes in Drought Characteristics in Korea Peninsula Using Effective Drought Index)

  • 곽용석;조재필;정임국;김도우;장상민
    • 한국기후변화학회지
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    • 제9권1호
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    • pp.31-45
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    • 2018
  • This study implemented the prediction of drought properties (number of drought events, intensity, duration) using the user-oriented systematical procedures of downscaling climate change scenarios based the multiple global climate models (GCMs), AIMS (APCC Integrated Modeling Solution) program. The drought properties were defined and estimated with Effective Drought Index (EDI). The optimal 10 models among 29 GCMs were selected, by the estimation of the spatial and temporal reproducibility about the five climate change indices related with precipitation. In addition, Simple Quantile Mapping (SQM) as the downscaling technique is much better in describing the observed precipitation events than Spatial Disaggregation Quantile Delta Mapping (SDQDM). Even though the procedure was systematically applied, there are still limitations in describing the observed spatial precipitation properties well due to the offset of spatial variability in multi-model ensemble (MME) analysis. As a result, the farther into the future, the duration and the number of drought generation will be decreased, while the intensity of drought will be increased. Regionally, the drought at the central regions of the Korean Peninsula is expected to be mitigated, while that at the southern regions are expected to be severe.

저비용 수제 연신레오미터 개발 및 성능 평가 (Development and performance evaluation of a low-cost custom-made extensional rheometer)

  • 김시현;박한별;김정현
    • 한국가시화정보학회지
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    • 제21권1호
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    • pp.110-118
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    • 2023
  • Characterizing the extensional rheological properties of non-Newtonian fluids is crucial in many industrial processes, such as inkjet printing, injection molding, and fiber engineering. However, educational institutions and research laboratories with budget constraints have limited access to an expensive commercial extensional rheometer. In this study, we developed a custom-made extensional rheometer using a CO2 laser cutting machine and 3D printer. Furthermore, we utilized a smartphone with a low-cost microscopic lens for achieving a high spatial resolution of images. The aqueous polyethylene-oxide (PEO) solutions and a Boger fluid were prepared to characterize their extensional properties. A transition from a visco-capillary to an elasto-capillary regime was observed clearly through the developed rheometer. The extensional relaxation time and viscosity of the aqueous PEO solutions with a zero-shear viscosity of over 300 mPa·s could be quantified in the elasto-capillary regime. The extensional properties of the solutions with relatively small zero shear viscosity could be calculated using a smartphone's slow-motion feature with increasing temporal resolution of the images.

Direct Comparison of Optical Properties from Graphene Oxide Quantum Dots and Graphene Oxide

  • Jang, Min-Ho;Ha, Hyun Dong;Seo, Tae Seok;Cho, Yong-Hoon
    • Applied Science and Convergence Technology
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    • 제24권4호
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    • pp.111-116
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    • 2015
  • The graphene oxide (GO) and graphene oxide quantum dots (GOQDs), which have gained research interest as new types of light-emitting materials, were synthesized by the modified Hummers method for oxidation of graphite flake and graphite nanoparticle. The optical properties of GO and GOQDs have been compared by mean of photoluminescence (PL), PL excitation (PLE), UV-vis absorbance, and time-resolved PL. The GO have an absorption peak at 229 nm and shoulder part at 310 nm, whereas the GOQDs show broad absorption with a gradual change up without any absorption peaks. The PL emission of GOQDs and GO showed the green color at 520 nm and the red color at 690 nm, respectively. The red emission of GO showed faster PL decay time than the green emission of GOQDs. In particular, the temporal PL profile of the GO showed redshift from 560 nm to 660 nm after the pump event.

정적 연소실내 난류 예혼합화염 전파의 시뮬레이션 (Simulation of Turbulent Premixed Flame Propagation in a Closed Vessel)

  • 권세진
    • 대한기계학회논문집
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    • 제19권6호
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    • pp.1510-1517
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    • 1995
  • A theoretical method is described to simulate the propagation of turbulent premixed flames in a closed vessel. The objective is to develop and test an efficient technique to predict the propagation speed of flame as well as the geometric structure of the flame surfaces. Flame is advected by the statistically generated turbulent flow field and propagates as a wave by solving twodimensional Hamilton-Jacobi equation. In the simulation of the unburned gas flow field, following turbulence properties were satisfied: mean velocity field, turbulence intensities, spatial and temporal correlations of velocity fluctuations. It is assumed that these properties are not affected by the expansion of the burned gas region. Predictions were compared with existing experimental data for flames propagating in a closed vessel charged with hydrogen/air mixture with various turbulence intensities and Reynolds numbers. Comparisons were made in flame radius growth rate, rms flame radius fluctuations, and average perimeter and fractal dimensions of the flame boundaries. Two dimensional time dependent simulation resulted in correct trends of the measured flame data. The reasonable behavior and high efficiency proves the usefulness of this method in difficult problems of flame propagation such as in internal combustion engines.

RS 기법을 이용한 토양수분과 토양 색에 관련된 토양의 분광반사 (Spectral Reflectance of Soils Related to the Interaction of Soil Moisture and Soil Color Using Remote Sensing Technology)

  • 박종화
    • 한국농공학회지
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    • 제45권5호
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    • pp.77-84
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    • 2003
  • Recent advances in remote sensing techniques provide the potential for monitoring soil color as well as soil moisture conditions at the spatial and temporal scales required for detailed local modeling efforts. Soil moisture as well as soil color is a key feature used in the identification and classification of soils. Soil spectral reflectance has a direct relationship with soil color, as well as to other parameters such as soil moisture, soil texture. and organic matter. We evaluate the influence of seven soil properties, soil color and soil moisture, on soil spectral reflectance. This paper presents the results obtained from the ground-truth spectral reflectance measurements in the 300-1100 nm wavelength range for various land surfaces. The results suggest that the reflectance properties of soils are related to soil color, soil texture, and soil moisture. Increasing soil moisture content generally decreases soil reflectance which leads to parallel curves of soil reflectance spectra across the entire shortwave spectrum. We discuss the relationships between the soil reflectance and the Munsell Soil Color Charts which contain standard color chips with colors specified by designations for hue, value, and chroma.

Statistical Analysis of Pc1 Pulsations Observed by a BOH Magnetometer

  • Kim, Jiwoo;Hwang, Junga;Kim, Hyangpyo;Yi, Yu
    • Journal of Astronomy and Space Sciences
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    • 제37권1호
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    • pp.19-27
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    • 2020
  • Pc1 pulsations are important to consider for the interpretation of wave-particle interactions in the Earth's magnetosphere. In fact, the wave properties of these pulsations change dynamically when they propagate from the source region in the space to the ground. A detailed study of the wave features can help understanding their time evolution mechanisms. In this study, we statistically analyzed Pc1 pulsations observed by a Bohyunsan (BOH) magneto-impedance (MI) sensor located in Korea (L = 1.3) for ~one solar cycle (November 2009-August 2018). In particular, we investigated the temporal occurrence ratio of Pc1 pulsations (considering seasonal, diurnal, and annual variations in the solar cycle), their wave properties (e.g., duration, peak frequency, and bandwidth), and their relationship with geomagnetic activities by considering the Kp and Dst indices in correspondence of the Pc1 pulsation events. We found that the Pc1 waves frequently occurred in March in the dawn (1-3 magnetic local time (MLT)) sector, during the declining phase of the solar cycle. They generally continued for 2-5 minutes, reaching a peak frequency of ~0.9 Hz. Finally, most of the pulsations have strong dependence on the geomagnetic storm and observed during the early recovery phase of the geomagnetic storm.