• International Journal of Oral Biology
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• v.36 no.1
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• pp.37-42
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• 2011

The working mechanism of bisphosphonate on bone cells is unclear despite its powerful inhibitory activity on bone resorption. The differentiation and activation of osteoclasts are essential for bone resorption and are controlled by the stimulatory RANKL and inhibitory OPG molecules. Teeth exhibit a range of movement patterns during their eruption to establish their form and function, which inevitably accompanies peripheral bone resorption. Hence, the mandible, which contains the teeth during their eruption processes, is a good model for revealing the inhibitory mechanism of bisphosphonate upon bone resorption. In the present study, RANKL and OPG expression were examined immunohistochemically in the mandible of rats with developing teeth after alendronate administration (2.5 mg/kg). The preeruptive mandibular first molars at postnatal days 3 to 10 showed the developing stages from bell to crown. No morphological changes in tooth formation were observed after alendronate administration. The number of osteoclasts in the alveolar bone around the developing teeth decreased markedly at postnatal days 3, 7 and 10 compared with the control group. RANKL induced strong positive immunohistochemical reactions in the dental follicles and stromal cells around the mandibular first molar. In particular, many osteoclasts with strongly positive reactions to RANKL appeared above the developing mandibular first molars at postnatal days 3 and 10. Immunohistochemical reactions with RANKL after alendronate administration were weaker than the control groups. However, the immunohistochemical reactivity to OPG was stronger after alendronate administration, at postnatal days 3 and 10. These results suggest that alendronate may decrease bone resorption by regulating the RANKL/OPG pathway in the process of osteoclast formation, resulting in a delay in tooth eruption.

• Journal of the korean academy of Pediatric Dentistry
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• v.44 no.1
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• pp.56-63
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• 2017

Delayed eruption of the first molar, without a generalized or localized cause, is usually associated with delayed development of the affected tooth. The aim of this study was to investigate the clinical features of the first permanent molar showing delayed development and eruption, and its association with developmental anomalies of other teeth. Panoramic radiographs of 40 healthy children showing delayed development and eruption of first permanent molars were analyzed. The clinical features of affected first molars and developmental anomalies of other teeth (except third molars) were evaluated. Delayed first molars were more frequent in the maxilla. The incidence of bilateral delayed development of first molars was greater than that of unilateral cases in female patients. In contrast, male patients showed unilateral delayed development of the first molar more frequently. A higher incidence of congenitally missing teeth was observed in patients with delayed first molar. In each case, delayed development or congenital absence was observed in the second molar adjacent to the delayed first molar. Overall, delayed first molar seems to be associated with congenital absence of additional teeth. Understanding the developmental mechanisms of this phenomenon requires further studies.

• Journal of the korean academy of Pediatric Dentistry
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• v.41 no.1
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• pp.85-92
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• 2014

Dentigerous cyst is the most common developmental odontogenic cyst of the jaw which is associated with unerupted teeth. Treatment modalities range from enucleation to marsupialization. Enucleation is the process in which the cyst is completely removed, and this is usually indicated for smaller lesions. Larger cysts can be treated by marsupialization, which is a process that consists of making a surgical cavity on the wall of the cyst, emptying its content and maintaining the continuity between the cyst and the oral cavity. This procedure allows decompression of the cyst, regeneration of the bone-defected area, and also lets the wall of the cyst change into normal mucosa. This technique will protect adjacent structures and will promote spontaneous eruption of succedaneous teeth previously surrounded by the cyst. These are two case reports of a 5-year-old and an 11-year-old boy with dentigerous cysts found regarding supernumerary tooth and pulpotomized mandibular primary molars, respectively. Due to the large size of the cysts, both cases were treated with marsupialization. This case report shows that in cases regarding large-sized dentigerous cysts, marsupialization can be an effective surgical technique that promotes spontaneous eruption of cyst-involved succedaneous teeth and the preservation of adjacent teeth.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.10 no.2
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• pp.9-14
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• 2001

Autotransplantation of tooth has recently become a combined method with orthodontic therapy. With the use of autotransplantation, it has become possible for orthodontists to solve complicated problems in the dental arches. Autotransplanted teeth showed the same development as their contralaterals with respect to both eruption and root growth. This indicates that autotransplantation and orthodontic treatment is a method that should be considered in case of impacted, missing, or malformed teeth. In this report two cases are presented to demonstrate that orthodontic treatment with autotransplantation can contribute to more satisfactory solution to the problem for impacted teeth.

• The Journal of the Korean dental association
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• v.50 no.6
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• pp.312-321
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• 2012

Permanent canine are very important teeth in point of function as well as esthetic. Therefore impaction of canines is a frequently encountered clinical problems. The incidence of impaction ranges between 1-3%. The cause of canine impaction can be result of ectopic position of tooth germ, defect of dental follicle, early loss or delayed exfoliation primary canine, space problem, supernumarary teeth, cyst, odontoma, Impaction frequently involves further complication such as root resorption of adjacent teeth, cyst formation and migration of the neighboring teeth. Various treatment modalities include extraction of primary canine, surgical opening and orthodontic traction, autotransplantation, surgical extraction of impacted canine.

• Journal of the korean academy of Pediatric Dentistry
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• v.24 no.4
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• pp.788-794
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• 1997

As one of the developmental disturbance in shape of teeth, a twinning has very rare frequency in permanent teeth. Because it is possible to diagnose the twinning by use of the radiograph, it is very important to detect this anomaly early by careful examining the radiographs. The twinning produces several orthodontic problem such as crowding, protrusion, ectopic eruption of adjacent teeth. Therefore it is necessary, in proper time, the extraction and orthodontic treatment should perform.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.21 no.2
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• pp.393-403
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• 1991

The purpose of this study was to evaluate the incidence and radiographic features of 1,300 cases of supernumerary teeth by means of the analysis of periapical radiograms and/or pantomograms in 69,442 persons visited the Department of Oral Radiology, School of Dentistry, Kyung Hee University during January 1980 to December 1989. This study of supernumerary teeth revealed the following features: 1. The incidence of supernumerary tooth was revealed to be 1.5% in total examined persons, and there was a higher incidence in males (74.0%) than in females (26.0%). 2. The supernumerary teeth were most frequently occurred in the 1 st decade (42.7%), followed by the 2nd decades (20.2%), the 3rd decades (14.1 %), and the 5th decades (7.2%). 3. There was a higher incidence in the maxilla (98.7%) than in the mandible (1.3%), and mesiodens (90.1 %) was the most frequently occurred. The maxillary lateral incisor region (3.1%) was next in order of frequency followed by maxillary distomolar (2.2%), and maxillary paramolar (1.5%). 4. There was a higher incidence of the impaction (82.7%) than that of the eruption (17.3%), and supernumerary tooth in lateral incisor region (87.8%) was the most frequently impacted one. 5. The inverted impaction was occurred in 63.1%, the vertical impaction in 18.1%, and the angulated impaction in 18.8%. In localization, a palatally (lingually) impacted supernumerary tooth was occurred in 85.0%, and middle impacted and buccally (labially) impacted supernumerary tooth showed the same incidence (7.5%). 6. A supplemental tooth was occurred in 3.2%, an accessory tooth in 96.8%, and a supplemental tooth was the most frequently occurred in maxillary lateral incisor and mandibular premolar region. 7. In effects of supernumerary tooth on adjacent tooth, crowding was occurred in 0.4%, diastema in 10.6%, rotation in 5.4%, eruption disturbance in 4.5%, root resorption in 2.5%, and dentigerous cyst in 2.2%.

• The Journal of the Korean dental association
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• v.49 no.4
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• pp.211-218
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• 2011

Purpose: An impacted tooth is defined as a tooth that shows delayed eruption and is expected to erupt incompletely by clinical and radiograph examination despite it reaching its expected time of eruption. The aims of this study were to investigate the clinical and radiological characteristics and treatment duration and method of impacted teeth in Korean patients. Materials and Methods: For this study we used clinical records, study models, panoramic radiographs and intraoral photographs of patients who attended Gachon University Gil Hospital Orthodontic Department between 2005 and 2008. There were 164 patients with a total number of 202 impacted teeth. Results: Male patients shows a little more prevalence than female patients (1.13:1). The under 12 age group had the highest prevalence of tooth impaction, and the over 19 age group showed the least prevalence of tooth impaction. The ratio of tooth impaction between the left to right ratio was 1.73:1 and maxilla and mandible was 1.84:1. The impacted teeth were most commonly positioned buccally (76 cases, 41.5%). Full nap closure technique (108 cases, 81.2%)was most frequently used for attachment of surgical traction hooks. Maxillary canine impaction was most commonly encountered both in male and female patients. The mean treatment period was 12.2 months and the success rate of treatment was 90.3%. The canine tooth shows the longest treatment time and highest failure rate. The ankylosis was the major cause of failure. Conclusion: Impacted teeth most commonly show in left side maxilla in the under 12 age group. And it is most commonly positioned buccally. The mean treatment period was 12.2 months, and the success rate of treatment was 90.3%.

• Journal of the korean academy of Pediatric Dentistry
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• v.42 no.3
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• pp.257-263
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• 2015

Impacted teeth occur at higher frequencies in permanent than primary dentition. The most frequently affected teeth are the maxillary and mandibular third molars, whereas it is quite uncommon for the mandibular first molar to be impacted. Treatment methods for impacted teeth include continuous examination for independent eruption, surgical exposure, subluxation after surgical exposure, orthodontic traction, and surgical repositioning. If all of these treatments fail, tooth extraction may be considered. In the first case study, an 8-year-old boy was treated with surgical exposure, after which he was fitted with an obturator. His mandibular first molar then erupted successfully. In the second case, we treated a 12 year-old boy using orthodontic traction. This study describes children with tooth eruption disorders of the mandibular first molar in mixed dentition, and reports acceptable results regarding treatment of the impacted teeth.

• The Journal of the Korean dental association
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• v.10 no.6
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• pp.339-346
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• 1972