• Polymer(Korea)
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• v.35 no.2
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• pp.113-118
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• 2011

Solid dispersion is used to improve the solubility of water-insoluble drug. Release properties depend on the characteristics of polymer and the physicochemical properties of solid dispersion. In this study the solid dispersions of ibuprofen and cellulose acetate were prepared using spray-drying and rotary evaporation. The physicochemical properties of the solid dispersions were analyzed by SEM, XRD, DSC, and FTIR. The hydrophilicity of polymer was analyzed by measuring the contact angle of water. The results of DSC and XRD analysis demonstrated that the crystallinity of ibuprofen was changed by solid dispersion preparation. The results of contact angle showed that hydrophilicity was proportional to polymer content. Release profile showed that for solid dispersion. the release rate of ibuprofen decreased as polymer content increased in intestinal juice (pH 6.8). The dissolution rate of ibuprofen was improved with increasing polymer content in gastric juice (pH 1.2).

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.8
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• pp.2749-2763
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• 2021

The desirable result of infrared (IR) and visible (VIS) image fusion should have textural details from VIS images and salient targets from IR images. However, detail information in the dark regions of VIS image has low contrast and blurry edges, resulting in performance degradation in image fusion. To resolve the troubles of fuzzy details in dark regions of VIS image fusion, we have proposed a method of reflectance estimation for IR and VIS image fusion. In order to maintain and enhance details in these dark regions, dark region approximation (DRA) is proposed to optimize the Retinex model. With the improved Retinex model based on DRA, quasi-Newton method is adopted to estimate the reflectance of a VIS image. The final fusion outcome is obtained by fusing the DRA-based reflectance of VIS image with IR image. Our method could simultaneously retain the low visibility details in VIS images and the high contrast targets in IR images. Experiment statistic shows that compared to some advanced approaches, the proposed method has superiority on detail preservation and visual quality.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2009.03a
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• pp.185-186
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• 2009

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2010.03a
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• pp.197-198
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• 2010

• Proceedings of the Korea Technology Innovation Society Conference
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• 2000.05a
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• pp.154-173
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• 2000

Since computerized numerical controller (CNC) emerged as a result of the fusion of the electronics technology and the mechanical technology, there has been continuous evolution of CNC technology in the mechatronics industry. The industry is recently developing a new control system based on the fusion of personal computer (PC) and CNC. Upgraded PC has now integrated into CNC, making various machines possible to exchange data, software and hardware, and to greatly improve man-machine interface. The fusion of PC and CNC can form a new paradigm in technological innovation of not only control system but also whole machinery industry in near the future. Korea lagged behind the developed countries in the development of open control system with the fusion of PC. Turbo-tek, Hyundai Motor and Daewoo are leading companies, but their commercial possibility seems to be low because domestic market is too small to reap a commercial benefit. Nevertheless, the development of the system is an essential step for Korea to embark on a future technological paradigm of the machinery industry. The government needs to play some role for the development, for instance, government R&D projects, institutional building and training of related technicians.

• Journal of Astronomy and Space Sciences
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• v.20 no.4
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• pp.359-364
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• 2003

In this paper, we present multi-sensor data fusion for telematics application. Successful telematics can be realized through the integration of navigation and spatial information. The well-determined acquisition of vehicle's position plays a vital role in application service. The development of GPS is used to provide the navigation data, but the performance is limited in areas where poor satellite visibility environment exists. Hence, multi-sensor fusion including IMU (Inertial Measurement Unit), GPS(Global Positioning System), and DMI (Distance Measurement Indicator) is required to provide the vehicle's position to service provider and driver behind the wheel. The multi-sensor fusion is implemented via algorithm based on Kalman filtering technique. Navigation accuracy can be enhanced using this filtering approach. For the verification of fusion approach, land vehicle test was performed and the results were discussed. Results showed that the horizontal position errors were suppressed around 1 meter level accuracy under simulated non-GPS availability environment. Under normal GPS environment, the horizontal position errors were under 40㎝ in curve trajectory and 27㎝ in linear trajectory, which are definitely depending on vehicular dynamics.

• Nuclear Engineering and Technology
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• v.51 no.4
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• pp.1142-1153
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• 2019

This paper presents the effect of fusion procedure on the fusion performance of the thermal butt fusion in the safety class III buried HDPE piping per various tests performed, including high speed tensile impact, free bend, blunt notched tensile, notched creep, and PENT tests. The suitability of fusion joints and qualification procedures was evaluated by comparing test results from the base material and buttfusion joints. From the notched tensile test result, it was found that the fused joints have much lower toughness than the base material. It was also identified that the notched tensile test is more desirable than the high speed tensile impact and free bend tests presented in the ASME Code Case N-755-3 as a fusion qualification test method. In addition, with regard to the single low-pressure fusion joint performances, the procedure given by the ISO 21307 was determined to be better that the one specified in the Code Case N-755-3.

• Journal of Microbiology and Biotechnology
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• v.20 no.10
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• pp.1430-1435
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• 2010

Two angiostatic fusion proteins (hAE and hEA), differing in tandem connection manners, were constructed from human angiostatin (hAS) and endostatin (hES) proteins. These fusion proteins were then evaluated for synergistic antiangiogenic properties. The 65 kDa secreted fusion proteins, expressed in Pichia pastoris, were verified by both mass analysis and Western blotting assay. Luciferase reorter gene assay, using a VEGF promoter, revealed that the angiostatin-endostatin fusion protein (hAE), and its corresponding fusion gene delivery on human microvascular endothelial cells (HMEC-1), resulted in a more potent synergistic antiangiogenic effect than the endostatin-angiostatin fusion protein (hEA). These results suggest that the orientation of the fusion genes in hAS and hES might be an important factor in the development of therapeutic proteins.

• Journal of Information Processing Systems
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• v.15 no.6
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• pp.1296-1305
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• 2019

To solve the problem of poor noise suppression capability and frequent loss of edge contour and detailed information in current fusion methods, an infrared and visible light image fusion method based on variational multiscale decomposition is proposed. Firstly, the fused images are separately processed through variational multiscale decomposition to obtain texture components and structural components. The method of guided filter is used to carry out the fusion of the texture components of the fused image. In the structural component fusion, a method is proposed to measure the fused weights with phase consistency, sharpness, and brightness comprehensive information. Finally, the texture components of the two images are fused. The structure components are added to obtain the final fused image. The experimental results show that the proposed method displays very good noise robustness, and it also helps realize better fusion quality.

• Journal of the Korea Institute of Military Science and Technology
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• v.15 no.5
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• pp.676-686
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• 2012

This paper presents a sensor bias estimation method with serial fusion for asynchronous multisensory systems. Serial fusion processes the sensor measurements in a first-come-first-serve basis and it plays an essential role in asynchronous fusion in practice. The proposed algorithm generates the bias measurements using fusion estimates and sensor measurements for bias estimation, and compensates the sensor biases in fusion tracks. A simulation study indicates that the proposed algorithm has the superior performance in bias estimation and accurate tracking.