• Journal of Veterinary Clinics
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• v.20 no.2
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• pp.207-211
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• 2003

This investigation aimed to determine the relative merit of osseointegration in immediate and delayed implantation in the dog mandible using radiography and bone scintigraphy. five adult mongrel dogs with a mean weight of 8.5 kg were used in this investigation. During the entire study period. all dogs were fed with a soft commercial diet and water ad libitum to minimize functional loading of the implant. Twenty titanium alloy systems 4 mm in diameter and 10 mm in length blasted with calcium phosphate were prepared for insertion. The second and third left mandibular premolars in each dog were extracted for the delayed implant insertion. Twelve weeks later, the second and third right mandibular premolars were extracted for the immediate implant insertion. Before the delayed and immediate implantation procedures and 0, 4, 8, and 12 weeks after the insertions, radiography and bone scintigraphy were conducted. Bone scans were obtained using a large field of view gamma camera equipped with a collimator about 3 hours after intravenous injection of Tc-99m-MDP to the dogs. All the dogs were evaluated weekly for inflammation, necrosis, and other of the bone or sort tissue. Significant macroscopic lesions were not detected. Radioisotope scintigraphy with Tc-99m-MDP hat proved to be a reliable method for measuring increased bone activity at specific skeleton tissue sites. In conclusion, osseointegration in peri-implant bone did not differ significantly between the immediate and delayed implant procedures during the experimental period. The immediate implant may be an alternative treatment of implant insertion in animals.

• Journal of radiological science and technology
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• v.30 no.3
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• pp.245-250
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• 2007

This research measured the shielding rates of apron 0.25 and 0.5 mmPb for X-ray energy in diagnosis radiation system and gamma-ray energy of $^{99m}Tc$-MDP and $^{18}F$-FDG. X-ray energies were measured on effective energy of $26.2{\sim}45.6\;keV$ when additional filtering plate of 0, 2 mmAl is used within the range of tube voltage $40{\sim}120\;kVp$, and at this time, apron 0.5 mmPb has shown about 5.5% of increase in its shielding rate over 0.25 mmPb at the highest quality. Besides, the aprons of the two types have shown high shielding rate of over 90% for direct X-ray and spatial dose rate. And, in case 0.25 and 0.5 mmPb aprons were used at 140keV of $^{99m}Tc$-MDP, the shielding effects were between 30 and 53%, and at high energy of 511 keV, $^{18}F$-FDG, the shielding effects of apron, $1.3{\sim}3.6%$, were very small.

• The Korean Journal of Nuclear Medicine
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• v.34 no.5
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• pp.433-435
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• 2000

A 6000-year-old male with carcinoma of the prostate and cerebral infarction underwent a Tc-99m MDP bone scintigraphy for the evaluation of skeletal metastases. Bone scintigraphy (Fig. 1) showed multiple areas of increased uptake of Tc-99m MDP in the skull, spine, and ribs representing skeletal metastases. Two different patterns of uptake occurred in the skull region (Fig. 1A-C); one represents bony metastasis and the ether represents cerebral infarction. The shape, size, location, intensity, and border of the increased uptake differed between the two lesions. An oval-shaped pattern with smaller size, greater intensity and more sharply defined border in the frontal region was consistent with bony metastasis. A rectangular-shaped pattern with larger size, lesser intensity and relatively indistinct border in the temporo-parieto-occipital region was consistent with cerebral infarction. Increased uptake of bone-seeking radiotracers in cerebral infarction has been reported previously.$^{1-4)}$ A suggested mechanism by which bone-seeking radiotracers accumulate in the necrotizing cerebral tissue is an alteration of the blood-brain barrier induced during cerebral infarction, which results in entry of the radiotracers into the extracellular space of the brain.$^{4)}$ Brain CT (Fig. 2) performed 7 days before and one month after the bone scintigraphy revealed lesions on the right temporo-parieto-occipital region consistent with acute hemorrhagic and chronic cerebral infarction, respectively.

• 대한핵의학회:학술대회논문집
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• 2000.05a
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• pp.71.2-71.2
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• 2000

• Nuclear Medicine and Molecular Imaging
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• v.43 no.2
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• pp.154-155
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• 2009

A 45-year-old man presented with fatigue and weight loss underwent a Tc-99m MDP bone scan because of increased serum alkaline phosphatase. Delayed images at 4 hours demonstrated diffuse increased activity throughout both lobes of the thyroid in the absence of activity of the stomach and salivary glands. Thyroid laboratory indices and a Tc-99m pertechnetate thyroid scan suggested Graves' hyperthyroidism.

• The Korean Journal of Nuclear Medicine
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• v.16 no.2
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• pp.85-89
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• 1982

Patients with diffusely increased uptake in both kindeys("hot kidney") on the $^{99m}Tc-MDP$ bone imagings were evaluated. Total incidence of the "hot kidney" was 2.7% (56/2053). Among 56 patients with "hot kidney", the most common diseases were malignancies (30), and the remainders were composed of renal diseases(11) and other disease group(16). We report the possible factors for the "hot kidney" with brief review of some literatures.

• The Korean Journal of Nuclear Medicine
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• v.20 no.1
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• pp.45-52
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• 1986

In osteoarthritis of knee, sensitive and reproducible methods of evaluation are of particular importance in unicompartmental surgery, in which choice of technique and prognosis depend on accurate preoperative knowledge of distribution and extent of disease. The various diagnostic modalities for evaluation of osteoarthritic knee are present but it is known that $^{99m}Tc-MDP$ scintigraphy is the most sensitive and noninvasive method. The authors made a comparative study of scintigraphic findings and radiographic findings of 54 cases of osteoarthritic knees at Kyung Hee University Hospital from May' 83 to August' 85. The results were as follow: 1) $^{99m}Tc-MDP$ scintigraphy appeared more sensitive not only in detection of abnormal compartment but also in evaluation of severity of the diseased compartment compared to radiography. 2) We suggest that bone scintigraphy is most sensitive for preoperative information of extent and severity of the disease related to surgical technique and prognosis.

• The Korean Journal of Nuclear Medicine
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• v.20 no.1
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• pp.17-24
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• 1986

Authors enumerate various malignant and benign cases which showed soft tissue uptake of $^{99m}Tc-MDP$. We hope it might be a help in understanding and interpreting bone scans. Among 10,361 $^{99m}Tc-MDP$ bone scans underwent from April, 1981 to March, 1986, 344 (3.3%) showed abnormal soft tissue uptake, which included 126 malignancies, 5 benign tumors, and 153 nontumorous diseases. Neuroblastoma(23.3%) and malignant fibrous histiocytoma(22.2%) showed highest positive uptake rate among various malignancies. We also illustrated typical cases according to possible mechanisms.

• The Korean Journal of Nuclear Medicine
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• v.27 no.2
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• pp.256-260
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• 1993

Thirteen patients received a coralline hydroxyapatite sphere as a buried integrated ocular implant after enucleation surgery. The implant was modified by multiple drillings, 1 mm in diameter, to the center of the sphere to allow more rapid host tissue ingrowth. $^{99m}Tc$-MDP planar and tomographic bone scintigraphies were performed at various intervals after implantation (from 100 to 742 days after operation) to assess vascularization of the implant. All patients showed hot uptakes in the implants. These patients underwent a secondary drilling for the final motility peg application. The confirmation of vascular ingrowth was done by inspection of bleeding at the time of bleeding at the time of drilling from the center of the implant. Bleeding from the drilled implant was noted in all patients. In cnclusion, hot uptake in the implanted ocular hydroxyapatite implant accurately reflect vascular ingrowth into the implant.

• The Korean Journal of Nuclear Medicine
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• v.29 no.1
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• pp.73-78
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• 1995

[ $^{99m}Tc$ ]-MDP bone scan was performed in 31 patients with primary malignant bone tumors, 22 patients with osteogenic sarcoma, 5 patients with chondrosarcoma and 4 patients with Ewing's sarcoma. The findings were classified by isotope intensity of accumulation in tumor as grade 1 to 3, overall pattern of isotope distribution in tumor as grade 1 to 3, and distortion of bony outline as grade 1 to 3. Histologic classifications were cor related with scan findings in 22 patients with osteogenic sarcoma. The results were as follows 1) In 22 patients with osteogenic sarcoma, markedly increased isotope intensity higher than sacroiliac joint with patchy areas of decreased intensity and severe bony distortion were found in 16 patients. The correlations between histologic classification and scan findings were not discovered. 2) In 5 patients with chondrosarcoma, mildly increased isotope Intensity with patchy areas of increased intensity and mild bony distortion were found in 4 patients.. 3) In 4 patients with Ewing's sarcoma, markedly increased homogenous intensity with moderate bony distortion were found in 3 patients. Conclusively there were common findings in each 3 primary malignant bone tumors and $^{99m}Tc$-MDP bone scan was complemented with radiologic studies in differentiating primary malignant bone tumors.