• International Commerce and Information Review
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• v.13 no.3
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• pp.3-29
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• 2011

The Internet has become a medium through which people engage in increasingly sophisticated transactions. Businesses and consumers now use the Internet to communicate and engage in commercial transactions creating a virtual worldwide marketplace. They fear that the determination of Internet jurisdiction could be uncertain because electronic commerce is not executed in one particular place. Until now, there are no specific rules in the model laws and conventions dealing with international jurisdiction in electronic commerce. Due to the fact that U.S. companies are at the forefront of Internet technology, litigation regarding electronic commerce in the U.S. is more advanced than anywhere else in the world This paper analysis the basic framework for personal jurisdiction and approach for determining international jurisdiction in electronic commerce cases and explain the differences of several approaches involving interactions over the Internet. According to jurisdiction approach test, the U.S. employs sliding scale, effects and targeting test in electronic commerce. In recent many research views the targeting test as a global standard for determining international electronic commerce jurisdiction. However, there is still no clear indication of conclusive test of jurisdiction determination for electronic commerce. Therefore, it is a changing and process of jurisdiction test in the U.S. cases. In Korea, there is jurisdiction related clause in Private International Law, but it may be asked whether applicable in electronic commerce. Accordingly, analysis of the precedents changing related to electronic commerce jurisdiction of U.s. is full of suggestions in Korean companies, consumers and helps an enactment of code of civil procedure that containing many group's demands.

• IMMUNE NETWORK
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• v.13 no.4
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• pp.157-162
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• 2013

Application of vaccine materials through oral mucosal route confers great economical advantage in animal farming industry due to much less vaccination cost compared with that of injection-based vaccination. In particular, oral administration of recombinant protein antigen against foot-and- mouth disease virus (FMDV) is an ideal strategy because it is safe from FMDV transmission during vaccine production and can induce antigen-specific immune response in mucosal compartments, where FMDV infection has been initiated, which is hardly achievable through parenteral immunization. Given that effective delivery of vaccine materials into immune inductive sites is prerequisite for effective oral mucosal vaccination, M cell-targeting strategy is crucial in successful vaccination since M cells are main gateway for luminal antigen influx into mucosal lymphoid tissue. Here, we applied previously identified M cell-targeting ligand Co1 to VP1 of FMDV in order to test the possible oral mucosal vaccination against FMDV infection. M cell-targeting ligand Co1-conjugated VP1 interacted efficiently with M cells of Peyer's patch. In addition, oral administration of ligand-conjugated VP1 enhanced the induction of VP1-specific IgG and IgA responses in systemic and mucosal compartments, respectively, in comparison with those from oral administration of VP1 alone. In addition, the enhanced VP1-specific immune response was found to be due to antigen-specific Th2-type cytokine production. Collectively, it is suggested that the M cell-targeting strategy could be applied to develop efficient oral mucosal vaccine against FMDV infection.

• Food Science and Industry
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• v.52 no.1
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• pp.32-39
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• 2019

The domestic food industry intends to expand overseas market. In order to succeed, in-depth research on local consumers is essential. This paper examined consumer research methodology and case studies based on sensory and consumer science for developing products targeting overseas market. Consumer research should be prece ded by overseas consumer panel construction. Then, this can be followed by application of various consumer research methodologies on new product development process. The most important consideration in this case is that application of same research methods or criteria as for domestic market could lead to significant errors in terms of reliability of results. Therefore, in order to develop successful products that accurately meet the needs of overseas consumers, careful study and consideration of the differences between markets would be essential from consumer researcher and decision-maker's sides.

• The Journal of Korean Society for Neurotherapy
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• v.22 no.3
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• pp.11-18
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• 2018

Purpose This study is to investigate the effect of sling exercise on the balance capacity of spastic diplegia cerebral palsy patient based on Bobath concept. Methods A single subject experiment was designed targeting an 8year old child with the rigid bilateral cerebral palsy. The static balance test used the 30 second Rombug test of BT4, and the dynamic balance test used the timed up and go test. Results In the 30second Rombug test of BT4, the child had a smaller median outcome than baseline and withdrawal period. In the TUG test, the walking speed in the intervention period was improved comparing to the baseline and withdrawal period. Conclusion The sling exercise based on the Bobath concept has been proved that it is an effective intervention to improve the static and dynamic balance capacity of patients with rigid bilateral cerebral palsy.

• Toxicological Research
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• v.27 no.3
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• pp.133-135
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• 2011

The FDA guidance focuses on the use of the NOAEL to establish the maximum recommended starting dose. The majority of NOAEL has been described inaccurately or incompletely in final reports for 90-days repeated dose toxicity test based on GLP (good laboratory practice) regulation. This is the most serious one of reasons for why most pharmaceutical companies targeting global markets have disregarded the final report produced from GLP facilities in Korea. The problems in deciding NOAEL reflected in the final reports are mainly due to the followings; 1) Inaccurate description or use of NOEL, NOAEL and LOAEL, 2) Insufficient and inappropriate interpretations in findings from toxicity test. This paper is intended to provide the insight into distinguishing NOAEL from NOEL and LOAEL, and into classifying findings from toxicity test. Here, the three step method is newly suggested by applying the weight-based classification to the NOEL, NOAEL and LOAEL based on the findings.

• Journal of Korean Biological Nursing Science
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• v.18 no.3
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• pp.185-191
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• 2016

Purpose: The purpose of this study is to understand the effect of taking calcium/vitamin D supplements and performing Taekkyeon exercises on the frailty of the elderly targeting a vulnerable senior social group. Methods: A total of 124 people aged 65 and older consisting of 60 persons in the experimental group, and 64 persons in the control group participated in this study, and this study is a non-equivalent control group pre/post-test design quasi-experimental study. This study analyzed the homogeneity between the experimental group and the control group using a chi-square test and t-test while analyzing the difference in the degree of frailty and bone density with the practice of Taekkyeon and a calcium agent using t-test and GEE. Results: The study results showed that the frailty and bone density of the experimental group significantly improved. Conclusion: Through this study, it was confirmed that calcium/vitamin D intake and Taekkyeon exercises were an effective intervention which strengthened the elderly's physical condition.

• Spatial Information Research
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• v.18 no.1
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• pp.1-10
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• 2010

Even after many constructions of test-beds to verify R&D results, there is no standard to set up a consistent and systematic test-bed master plan. Therefore, this research derives standards of a u-city test-bed master plan. To verify these standards, the research constructs the potential U-City master plan targeting Cheongna district in Incheon. Standards of a test-bed master plan which is suggested by this research will bring strengths to construct a test-bed such as clear construction procedures from presenting directions of planning, saving cost, effective management of equipments, and so on.

• Proceedings of the Korea Concrete Institute Conference
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• 2004.11a
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• pp.509-512
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• 2004

This research is targeting that estimate the effect on cement concrete pavement with type of chloride deicers. In order to this study objective, when chloride deicers were spread on road surface, thermal characteristics test was conducted. Also, skid resistance test according to types and concentration of chloride deicier, road surface conditions were investigated. As a test results, thermal characteristics with kind of chloride deicier could know that sodium chloride(NaCl) is exothermic reactive material, calcium chloride$(CaCl_2)$ is endothermic reactive material. And, in case of mixed salt of the calcium and sodium chloride, it could know that can change to the exothermic or endothermic reaction according to dosage ratios. Skid value by British Pendulum Tester(BPT) has shown that it is seldom difference between the types($CaCl_2$, NaCl, mixed salt) and solution concentrations(0.5, 0.8, 1.0, 4.0, $10\%$) of chloride deicier comparing with tap water except mixed salt($10\%$ solution concentration).

• Parasites, Hosts and Diseases
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• v.54 no.3
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• pp.329-334
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• 2016

Trichomoniasis caused by Trichomonas vaginalis is a common sexually transmitted disease. Its association with several health problems, including preterm birth, pelvic inflammatory disease, cervical cancer, and transmission of human immunodeficiency virus, emphasizes the importance of improved access to early and accurate detection of T. vaginalis. In this study, a rapid and efficient loop-mediated isothermal amplification-based method for the detection of T. vaginalis was developed and validated, using vaginal swab specimens from subjects suspected to have trichomoniasis. The LAMP assay targeting the actin gene was highly sensitive with detection limits of 1 trichomonad and 1 pg of T. vaginalis DNA per reaction, and specifically amplified the target gene only from T. vaginalis. Validation of this assay showed that it had the highest sensitivity and better agreement with PCR (used as the gold standard) compared to microscopy and multiplex PCR. This study showed that the LAMP assay, targeting the actin gene, could be used to diagnose early infections of T. vaginalis. Thus, we have provided an alternative molecular diagnostic tool and a point-of-care test that may help to prevent trichomoniasis transmission and associated complications.

• Journal of Fashion Business
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• v.3 no.3
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• pp.15-26
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• 1999

The purpose of the study was to investigate brand images and fashion leaderships of women's wear manufacturers targeting middle-aged women or older women. Thus, this study was to be an exploratory study to investigate clothing behavior of elderly female consumers and search apprel niche-market for them. The questionnaire consists of questions on brand images, fashion leadership, and merchandise assortment. The subjects were to evaluate their brand images and rated on 5 point Likert-type scales of 29 adjectives. The fashion leadership of these brands was evaluated by the degree of fashion trends adopted on 7 aspects including fashion images, silhouettes, fabrics, colors, design details, accessories, and item-coordinations. For the survey, both interview and the subjects were 66 manufacturers which have national brands or designer brands. Among 44 respondents, 30 respondents were designers and the rest of them were merchandiser or shop managers. The SPSS PC+ package was used to calculate frequency, T-test, and cluster analysis. The results from survey of manufacturers targeting middle-aged women or older women are as follow: 1) The brand imges which they pursue are prestigious, practical, and elegance. 2) There were significant differences in brand images, and national brand manufacturers pursue stronger images in prestigious, chic, intelligent, competency, than designer brand manufacturers. 3) 40 brands were divided into two clusters. 36 brands were included in one cluster, and only 4 brand were belong to the other cluster. In this market, the image of feminity was grouped with the image of prestigious, chic, intelligent, competency. 4) In product planning, the adption level of fashion trends in 7 aspects was generally at medium level, but fashion trends were more adopted in fabric, color, and item-coordination.